Nicastrin Antibody | EMD Millipore MAB5556 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Nicastrin Antibody

catalog :

MAB5556

quantity :

100 µL

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

9C3

The same clone is also sold as:

BioLegend: 852301, 852302

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry, immunoprecipitation

citations: 12

Published Application/Species/Sample/Dilution	Reference
western blot; rat; 1:1000	Lundgren J, Ahmed S, Schedin Weiss S, Gouras G, Winblad B, Tjernberg L, et al. ADAM10 and BACE1 are localized to synaptic vesicles. J Neurochem. 2015;135:606-15 pubmed publisher
western blot; human	Inoue M, Hur J, Kihara T, Teranishi Y, Yamamoto N, Ishikawa T, et al. Human brain proteins showing neuron-specific interactions with Î³-secretase. FEBS J. 2015;282:2587-99 pubmed publisher
	Guix F, Sannerud R, Berditchevski F, Arranz A, HorrÃ© K, Snellinx A, et al. Tetraspanin 6: a pivotal protein of the multiple vesicular body determining exosome release and lysosomal degradation of amyloid precursor protein fragments. Mol Neurodegener. 2017;12:25 pubmed publisher
	Chun Y, Park Y, Oh H, Kim T, Yang H, Park M, et al. O-GlcNAcylation promotes non-amyloidogenic processing of amyloid-Î² protein precursor via inhibition of endocytosis from the plasma membrane. J Alzheimers Dis. 2015;44:261-75 pubmed publisher
	Schedin Weiss S, Inoue M, Teranishi Y, Yamamoto N, Karlstrom H, Winblad B, et al. Visualizing active enzyme complexes using a photoreactive inhibitor for proximity ligation--application on ?-secretase. PLoS ONE. 2013;8:e63962 pubmed publisher
	Hong I, Kang T, Yoo Y, Park R, Lee J, Lee S, et al. Quantitative proteomic analysis of the hippocampus in the 5XFAD mouse model at early stages of Alzheimer's disease pathology. J Alzheimers Dis. 2013;36:321-34 pubmed publisher
	Frykman S, Teranishi Y, Hur J, Sandebring A, Yamamoto N, Ancarcrona M, et al. Identification of two novel synaptic ?-secretase associated proteins that affect amyloid ?-peptide levels without altering Notch processing. Neurochem Int. 2012;61:108-18 pubmed publisher
	Hur J, Teranishi Y, Kihara T, Yamamoto N, Inoue M, Hosia W, et al. Identification of novel ?-secretase-associated proteins in detergent-resistant membranes from brain. J Biol Chem. 2012;287:11991-2005 pubmed publisher
	Frånberg J, Karlstrom H, Winblad B, Tjernberg L, Frykman S. gamma-Secretase dependent production of intracellular domains is reduced in adult compared to embryonic rat brain membranes. PLoS ONE. 2010;5:e9772 pubmed publisher
	Frykman S, Hur J, Frånberg J, Aoki M, Winblad B, Nahalkova J, et al. Synaptic and endosomal localization of active gamma-secretase in rat brain. PLoS ONE. 2010;5:e8948 pubmed publisher
	Kim J, Kleizen B, Choy R, Thinakaran G, Sisodia S, Schekman R. Biogenesis of gamma-secretase early in the secretory pathway. J Cell Biol. 2007;179:951-63 pubmed
	Haberkant P, Schmitt O, Contreras F, Thiele C, Hanada K, Sprong H, et al. Protein-sphingolipid interactions within cellular membranes. J Lipid Res. 2008;49:251-62 pubmed

product information

Catalog Number :

MAB5556

Subcategory :

Neuroscience

Product Name :

Anti-Nicastrin Antibody

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

Q92542

Host Name :

Mouse

Antigen :

Nicastrin

Clone :

9C3

Conjugate :

Ascites

Isotype :

IgG2b

Product Description :

Anti-Nicastrin Antibody

Cross Reactivity :

Human;Mouse;Rat

Immunogen :

Synthetic peptide corresponding to the C terminal 18 a.a. of mouse Nicastrin. Due to sequence similarity, it is expected that the antibody will react with most mammals.

Specificity :

Nicastrin.

Package Size :

100 µL

Uses :

Immunoprecipitation;Western Blotting;Immunocytochemistry

Storage :

Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.