Prion Protein Antibody, clone 2G11 | EMD Millipore MAB5542 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Prion Protein Antibody, clone 2G11

catalog :

MAB5542

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2G11

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

product information

Catalog Number :

MAB5542

Subcategory :

Neuroscience

Product Name :

Anti-Prion Protein Antibody, clone 2G11

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P23907

Host Name :

Mouse

Antigen :

Prion Protein

Clone :

2G11

Conjugate :

Purified

Isotype :

IgG2aκ

Product Description :

Anti-Prion Protein Antibody, clone 2G11

Cross Reactivity :

Rat;Human;Sheep;Mouse

Background :

The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. Alternative splicing results in multiple transcript variants encoding the same protein.

ALT Names :

CD230 antigen ;major prion protein ;prion protein;prion protein (p27-30) ;prion protein PrP;prion-related protein

Immunogen :

KLH conjugated synthetic linear peptide corresponding to the C-terminus.

Specificity :

Cat. # MAB5542 recognizes the C-terminus of Prion Protein.

Package Size :

100 μg

Uses :

Immunohistochemistry (Paraffin);Western Blotting

Storage :

Stable for 1 year at 2-8ºC from date of receipt.