Tau Antibody, Caspase Cleaved (truncated at Asp421) | EMD Millipore MAB5430 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Tau Antibody, Caspase Cleaved (truncated at Asp421)

catalog :

MAB5430

quantity :

100 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

tau-C3

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry

citations: 6

Published Application/Species/Sample/Dilution	Reference
western blot; mouse	Hu X, Li X, Zhao M, Gottesdiener A, Luo W, Paul S. Tau pathogenesis is promoted by AÎ²1-42 but not AÎ²1-40. Mol Neurodegener. 2014;9:52 pubmed publisher
	Kiprowska M, Stepanova A, Todaro D, Galkin A, Haas A, Wilson S, et al. Neurotoxic mechanisms by which the USP14 inhibitor IU1 depletes ubiquitinated proteins and Tau in rat cerebral cortical neurons: Relevance to Alzheimer's disease. Biochim Biophys Acta Mol Basis Dis. 2017;1863:1157-1170 pubmed publisher
	Tucker B, Mullins R, Streb L, Anfinson K, Eyestone M, Kaalberg E, et al. Patient-specific iPSC-derived photoreceptor precursor cells as a means to investigate retinitis pigmentosa. elife. 2013;2:e00824 pubmed publisher
	Garringer H, Murrell J, Sammeta N, Gnezda A, Ghetti B, Vidal R. Increased tau phosphorylation and tau truncation, and decreased synaptophysin levels in mutant BRI2/tau transgenic mice. PLoS ONE. 2013;8:e56426 pubmed publisher
	Noble W, Garwood C, Stephenson J, Kinsey A, Hanger D, Anderton B. Minocycline reduces the development of abnormal tau species in models of Alzheimer's disease. FASEB J. 2009;23:739-50 pubmed publisher
	Ramalho R, Viana R, Castro R, Steer C, Low W, Rodrigues C. Apoptosis in transgenic mice expressing the P301L mutated form of human tau. Mol Med. 2008;14:309-17 pubmed publisher

product information

Catalog Number :

MAB5430

Subcategory :

Neuroscience

Product Name :

Anti-Tau Antibody, Caspase Cleaved (truncated at Asp421)

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P10636

Host Name :

Mouse

Antigen :

Tau

Clone :

tau-C3

Conjugate :

Purified

Isotype :

IgG1

Product Description :

Anti-Tau Antibody, Caspase Cleaved (truncated at Asp421)

Cross Reactivity :

Human

Immunogen :

Peptide corresponding to the C-terminus of tau truncated as aspartic acid 421.

Specificity :

Reacts with Tau, caspase cleaved (truncated at Asp421). The antibody shows no reactivity with full length tau nor other tau C-terminal truncations. The antibody stains amyloid beta treated neurons and brain tissue in Alzheimer's disease, more specifically it stains a subset of neurofibrillary tangles, tau-containing neuritic plaques and neuropil threads.

Package Size :

100 µg

Uses :

ELISA;Western Blotting;Immunohistochemistry

Storage :

Maintain at 2-8°C in undiluted aliquots for up to 6 months after date of receipt.