Glutamate Receptor 3 Antibody, clone 3B3 | EMD Millipore MAB5416 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Glutamate Receptor 3 Antibody, clone 3B3

catalog :

MAB5416

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3B3

The same clone is also sold as:

Invitrogen: 32-0400

reactivity :

human, mouse, rat, rhesus macaque

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, immunohistochemistry - free floating section

citations: 23

Published Application/Species/Sample/Dilution	Reference
western blot; rat; 1:500	Peng X, Lister A, Rabinowitsch A, Kolaric R, Cabeza de Vaca S, Ziff E, et al. Episodic sucrose intake during food restriction increases synaptic abundance of AMPA receptors in nucleus accumbens and augments intake of sucrose following restoration of ad libitum feeding. Neuroscience. 2015;295:58-71 pubmed publisher
western blot; rat; 1:2000	Choi T, Jung S, Nah J, Ko H, Jo S, Chung G, et al. Low levels of methyl Î²-cyclodextrin disrupt GluA1-dependent synaptic potentiation but not synaptic depression. J Neurochem. 2015;132:276-85 pubmed publisher
immunohistochemistry - free floating section; rhesus macaque; 1:100	Kooijmans R, Self M, Wouterlood F, Belien J, Roelfsema P. Inhibitory interneuron classes express complementary AMPA-receptor patterns in macaque primary visual cortex. J Neurosci. 2014;34:6303-15 pubmed publisher
western blot; human; 1:1000	Tucholski J, Pinner A, Simmons M, Meador Woodruff J. Evolutionarily conserved pattern of AMPA receptor subunit glycosylation in Mammalian frontal cortex. PLoS ONE. 2014;9:e94255 pubmed publisher
western blot; human; 1:1000	Tucholski J, Simmons M, Pinner A, Haroutunian V, McCullumsmith R, Meador Woodruff J. Abnormal N-linked glycosylation of cortical AMPA receptor subunits in schizophrenia. Schizophr Res. 2013;146:177-83 pubmed publisher
immunohistochemistry - frozen section; rat; 1:30	Zhang J, Diamond J. Distinct perisynaptic and synaptic localization of NMDA and AMPA receptors on ganglion cells in rat retina. J Comp Neurol. 2006;498:810-20 pubmed
immunocytochemistry; rat; 1:200	King A, Chung R, Vickers J, Dickson T. Localization of glutamate receptors in developing cortical neurons in culture and relationship to susceptibility to excitotoxicity. J Comp Neurol. 2006;498:277-94 pubmed
immunohistochemistry; rat; 1:400 western blot; rat; 1:250-1:500	Talos D, Fishman R, Park H, Folkerth R, Follett P, Volpe J, et al. Developmental regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid receptor subunit expression in forebrain and relationship to regional susceptibility to hypoxic/ischemic injury. I. Rodent cerebral white matter and cortex. J Comp Neurol. 2006;497:42-60 pubmed
	Borroni B, Stanic J, Verpelli C, Mellone M, Bonomi E, Alberici A, et al. Anti-AMPA GluA3 antibodies in Frontotemporal dementia: a new molecular target. Sci Rep. 2017;7:6723 pubmed publisher
	Minbay Z, Serter Kocoglu S, Gok Yurtseven D, Eyigor O. Immunohistochemical localization of ionotropic glutamate receptors in the rat red nucleus. Bosn J Basic Med Sci. 2017;17:29-37 pubmed publisher
	Jacob A, Weinberg R. The organization of AMPA receptor subunits at the postsynaptic membrane. Hippocampus. 2015;25:798-812 pubmed publisher
	Zonouzi M, Renzi M, Farrant M, Cull Candy S. Bidirectional plasticity of calcium-permeable AMPA receptors in oligodendrocyte lineage cells. Nat Neurosci. 2011;14:1430-8 pubmed publisher
	Goel A, Xu L, Snyder K, Song L, Goenaga Vazquez Y, Megill A, et al. Phosphorylation of AMPA receptors is required for sensory deprivation-induced homeostatic synaptic plasticity. PLoS ONE. 2011;6:e18264 pubmed publisher
	Incontro S, Ramírez Franco J, Sánchez Prieto J, Torres M. Membrane depolarization regulates AMPA receptor subunit expression in cerebellar granule cells in culture. Biochim Biophys Acta. 2011;1813:14-26 pubmed publisher
	Yamazaki M, Fukaya M, Hashimoto K, Yamasaki M, Tsujita M, Itakura M, et al. TARPs gamma-2 and gamma-7 are essential for AMPA receptor expression in the cerebellum. Eur J Neurosci. 2010;31:2204-20 pubmed publisher
	Jarius S, Wandinger K, Horn S, Heuer H, Wildemann B. A new Purkinje cell antibody (anti-Ca) associated with subacute cerebellar ataxia: immunological characterization. J Neuroinflammation. 2010;7:21 pubmed publisher
	Montgomery K, Kessler M, Arai A. Modulation of agonist binding to AMPA receptors by 1-(1,4-benzodioxan-6-ylcarbonyl)piperidine (CX546): differential effects across brain regions and GluA1-4/transmembrane AMPA receptor regulatory protein combinations. J Pharmacol Exp Ther. 2009;331:965-74 pubmed publisher
	Sun X, Wolf M. Nucleus accumbens neurons exhibit synaptic scaling that is occluded by repeated dopamine pre-exposure. Eur J Neurosci. 2009;30:539-50 pubmed publisher
	Sim H, Hu B, Viapiano M. Reduced expression of the hyaluronan and proteoglycan link proteins in malignant gliomas. J Biol Chem. 2009;284:26547-56 pubmed publisher
	Gainey M, Hurvitz Wolff J, Lambo M, Turrigiano G. Synaptic scaling requires the GluR2 subunit of the AMPA receptor. J Neurosci. 2009;29:6479-89 pubmed publisher
	Gao C, Wolf M. Dopamine alters AMPA receptor synaptic expression and subunit composition in dopamine neurons of the ventral tegmental area cultured with prefrontal cortex neurons. J Neurosci. 2007;27:14275-85 pubmed
	Kim M, Chiego D, Bradley R. Ionotropic glutamate receptor expression in preganglionic neurons of the rat inferior salivatory nucleus. Auton Neurosci. 2008;138:83-90 pubmed
	Flores Otero J, Xue H, Davis R. Reciprocal regulation of presynaptic and postsynaptic proteins in bipolar spiral ganglion neurons by neurotrophins. J Neurosci. 2007;27:14023-34 pubmed

product information

Catalog Number :

MAB5416

Subcategory :

Neuroscience

Product Name :

Anti-Glutamate Receptor 3 Antibody, clone 3B3

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P42263

Host Name :

Mouse

Antigen :

Glutamate Receptor 3

Clone :

clone 3B3

Conjugate :

Purified

Isotype :

IgG1κ

Product Description :

Anti-Glutamate Receptor 3 Antibody, clone 3B3

Cross Reactivity :

Human;Mouse;Rat;Monkey

Background :

AMPA receptors mediate fast synaptic current at most excitatory synapses, with stoichiometry characterized by subtype composition.There are four types of AMPA selective GluR subunits (GluR1, GluR2, GluR3 and GluR4). Tetrameric or pentameric combinations of different subunits contributes to the functional diversity of AMPA receptors. The insertion or removal of GluR1/GluR4 oligomeric channels from postsynaptic membranes appears to be LTP/LTD activity dependent while GluR2/GluR3 oligomers are continuously cycling. Millipore’s anti-GluR2/3 antibody is useful for localizing expression of GluR2/GluR3 receptor assemblies in the PSD.

ALT Names :

AMPA-selective glutamate receptor 3;Glutamate receptor ionotropic, AMPA 3;glutamate receptor 3;glutamate receptor C;glutamate receptor subunit 3;glutamate receptor, ionotrophic, AMPA 3

Immunogen :

Fusion protein, N-terminus of GluR3

Specificity :

Reacts with Glutamate Receptor 3 (GluR3). No cross reactivity with GluR2.

Package Size :

100 μg

Uses :

Western Blotting;Immunocytochemistry;Immunohistochemistry;Immunohistochemistry (Paraffin)

Storage :

Stable for 1 year at from date of receipt.