Peripherin Antibody, clone 7C5 | EMD Millipore MAB5380 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Peripherin Antibody, clone 7C5

catalog :

MAB5380

quantity :

300 µL

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

7C5

The same clone is also sold as:

Novus Biologicals: NB300-220-0.1ml
Invitrogen: MA5-33100
LifeSpan Biosciences: LS-C204573
Rockland Immunochemicals: 900-301-E11
Abnova: MAB3348
OriGene: TA309213

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - frozen section

citations: 5

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - frozen section; mouse; 1:75; loading ...; fig 1c	Peng X, Studholme K, Kanjiya M, Luk J, Bogdan D, Elmes M, et al. Fatty-acid-binding protein inhibition produces analgesic effects through peripheral and central mechanisms. Mol Pain. 2017;13:1744806917697007 pubmed publisher
immunocytochemistry; human; 1:250	Liu Q, Spusta S, Mi R, Lassiter R, Stark M, Hoke A, et al. Human neural crest stem cells derived from human ESCs and induced pluripotent stem cells: induction, maintenance, and differentiation into functional schwann cells. Stem Cells Transl Med. 2012;1:266-78 pubmed publisher
immunohistochemistry - frozen section; rat	Buniel M, Glazebrook P, Ramirez Navarro A, Kunze D. Distribution of voltage-gated potassium and hyperpolarization-activated channels in sensory afferent fibers in the rat carotid body. J Comp Neurol. 2008;510:367-77 pubmed publisher
	Takanami K, Sakamoto H, Matsuda K, Satoh K, Tanida T, Yamada S, et al. Distribution of gastrin-releasing peptide in the rat trigeminal and spinal somatosensory systems. J Comp Neurol. 2014;522:1858-73 pubmed publisher
	Yuan A, Sasaki T, Kumar A, Peterhoff C, Rao M, LIEM R, et al. Peripherin is a subunit of peripheral nerve neurofilaments: implications for differential vulnerability of CNS and peripheral nervous system axons. J Neurosci. 2012;32:8501-8 pubmed publisher

product information

Catalog Number :

MAB5380

Subcategory :

Neuroscience

Product Name :

Anti-Peripherin Antibody, clone 7C5

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P41219

Host Name :

Mouse

Antigen :

Peripherin

Clone :

7C5

Conjugate :

Culture Supernatant

Isotype :

IgG1κ

Product Description :

Anti-Peripherin Antibody, clone 7C5

Cross Reactivity :

Bovine;Human;Pig;Rat

Background :

Peripherin is a ~57kDa intermediate filament subunit found initially in sensory neurons of the peripheral nervous systems. Subsequently it was found in some sensory and other neurons of the central nervous system and also in PC12 cells. Peripherin is also expressed in certain neuroendocrine tumors and in the insulin producing cells of the pancreas. Peripherin belongs to the Class III family of intermediate filament subunits which includes vimentin, glial fibrillary acidic protein (GFAP) and desmin. Antibodies to peripherin can be used in identifying, classifying, and studying neurons throughout the nervous system. Peripherin is also a good diagnostic marker for ballooned axons seen in Lou Gehrig's disease (Amyotrophic lateral sclerosis) and some neuronally derived tumors. Autoantibodies to peripherin are frequently seen in the sera of patients with diabetes. Peripherin is not related to peripherin/RDS, a protein of the photoreceptor outer membrane mutations of which are causative of certain forms of slow retinal degeneration.

Immunogen :

Recombinant rat peripherin.

Specificity :

Peripherin, class III neuronal intermediate filament protein. By western blot, the antibody detects a band migrating at approximately 57 kDa corresponding to peripherin; reactive with human, bovine, porcine and rat peripherin by western blot, other species not tested.

Package Size :

300 µL

Uses :

Western Blotting;Immunohistochemistry

Storage :

Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.