This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
EMD Millipore
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
product type :
antibody
product name :
Nestin Antibody, clone 10C2, Alexa Fluor® 488 conjugate
catalog :
MAB5326A4
quantity :
100 µL
clonality :
monoclonal
host :
mouse
conjugate :
AF488
clone name :
reactivity :
human
application :
immunocytochemistry
citations: 1
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; ; loading ...; fig s3a
Zeitler B, Froelich S, Marlen K, Shivak D, Yu Q, Li D, et al. Allele-selective transcriptional repression of mutant HTT for the treatment of Huntington's disease. Nat Med. 2019;25:1131-1142 pubmed publisher
product information
Catalog Number :
MAB5326A4
Subcategory :
Stem Cell Research
Product Name :
Anti-Nestin Antibody, clone 10C2, Alexa Fluor® 488 conjugate
Product Type :
Antibodies
Clonality :
Monoclonal Antibody
Gene ID :
P48681
Host Name :
Mouse
Antigen :
Nestin
Conjugate :
AlexaFluor®488
Isotype :
IgG1
Product Description :
Anti-Nestin Antibody, clone 10C2, Alexa Fluor® 488 conjugate
Cross Reactivity :
Human
Background :
Nestin, a large intermediate filament protein (class Type VI) expressed during development and in myotendinous and neuromuscular junctions. Nestin expression is restricted, typically disappearing by E18. Nestin is thought to be a reasonable neuronal marker; however, recent studies have found nestin expression in other cell types such as endothelial cells {Folia Biologica, 44(5):155, 1998}. Nestin identifies the most primitive neuroepithelium but also identifies many other embryonic tissues, so it is not specific for CNS. Nestin expression is seen in almost all GBMs (Glioblastoma mulitformes) and many melanomas (both primary and metastatic) but not in any metastatic carcinoma.
ALT Names :
Nestin10c2;NES;Nbla00170;FLJ21841
Immunogen :
Fusion protein corresponding to human Nestin.
Specificity :
This antibody recognizes human Nestin. Antibody is not reactive with rat or mouse Nestin protein.
Package Size :
100 µL
Uses :
Immunocytochemistry
Storage :
Maintain refrigerated at 2-8ºC protected from light in undiluted aliquots for up to 6 months from date of receipt.
company information
EMD Millipore
290 Concord Road
Billerica, Massachusetts 01821
bioscienceshelp@emdchemical.com
https://www.emdmillipore.com
888-854-3417
headquarters: United States
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

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