This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
EMD Millipore
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
product type :
antibody
product name :
Oxytocin Antibody, clone 4G11
catalog :
MAB5296
quantity :
100 μL
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
4G11

The same clone is also sold as:
reactivity :
prairie voles, Mandarin vole, goldfish, human, mouse, rat
application :
immunohistochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, immunohistochemistry - free floating section
citations: 31
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - frozen section; Mandarin vole; 1:7500; loading ...; fig 2d
He Z, Young L, Ma X, Guo Q, Wang L, Yang Y, et al. Increased anxiety and decreased sociability induced by paternal deprivation involve the PVN-PrL OTergic pathway. elife. 2019;8: pubmed publisher
  • immunohistochemistry; mouse; 1:750; loading ...; fig 5
Doslikova B, Tchir D, McKinty A, Zhu X, Marks D, Baracos V, et al. Convergent neuronal projections from paraventricular nucleus, parabrachial nucleus, and brainstem onto gastrocnemius muscle, white and brown adipose tissue in male rats. J Comp Neurol. 2019;527:2826-2842 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:500; loading ...; fig 5j
Jiang Z, Rajamanickam S, Justice N. Local Corticotropin-Releasing Factor Signaling in the Hypothalamic Paraventricular Nucleus. J Neurosci. 2018;38:1874-1890 pubmed publisher
  • immunohistochemistry - frozen section; goldfish; 1:200; loading ...; fig 6a
Mangiamele L, Gomez J, Curtis N, Thompson R. GPER/GPR30, a membrane estrogen receptor, is expressed in the brain and retina of a social fish (Carassius auratus) and colocalizes with isotocin. J Comp Neurol. 2017;525:252-270 pubmed publisher
  • immunohistochemistry - free floating section; mouse; 1:1000; loading ...; fig s6a
Lagerlof O, Slocomb J, Hong I, Aponte Y, Blackshaw S, Hart G, et al. The nutrient sensor OGT in PVN neurons regulates feeding. Science. 2016;351:1293-6 pubmed publisher
  • immunohistochemistry; mouse
Steinman M, Laredo S, Lopez E, Manning C, Hao R, Doig I, et al. Hypothalamic vasopressin systems are more sensitive to the long term effects of social defeat in males versus females. Psychoneuroendocrinology. 2015;51:122-34 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:600
Li X, Lytton J. An essential role for the K+-dependent Na+/Ca2+-exchanger, NCKX4, in melanocortin-4-receptor-dependent satiety. J Biol Chem. 2014;289:25445-59 pubmed publisher
  • immunohistochemistry - free floating section; prairie voles; 1:10000
Barrett C, Modi M, Zhang B, Walum H, Inoue K, Young L. Neonatal melanocortin receptor agonist treatment reduces play fighting and promotes adult attachment in prairie voles in a sex-dependent manner. Neuropharmacology. 2014;85:357-66 pubmed publisher
  • immunohistochemistry; human; 1:500
Deing V, Roggenkamp D, Kühnl J, Gruschka A, Stäb F, Wenck H, et al. Oxytocin modulates proliferation and stress responses of human skin cells: implications for atopic dermatitis. Exp Dermatol. 2013;22:399-405 pubmed publisher
  • immunohistochemistry; mouse; 1:2,500
Gautron L, Cravo R, Elmquist J, Elias C. Discrete melanocortin-sensitive neuroanatomical pathway linking the ventral premmamillary nucleus to the paraventricular hypothalamus. Neuroscience. 2013;240:70-82 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:25000
Sapsford T, Kokay I, Ostberg L, Bridges R, Grattan D. Differential sensitivity of specific neuronal populations of the rat hypothalamus to prolactin action. J Comp Neurol. 2012;520:1062-77 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:1000
Biag J, Huang Y, Gou L, Hintiryan H, Askarinam A, Hahn J, et al. Cyto- and chemoarchitecture of the hypothalamic paraventricular nucleus in the C57BL/6J male mouse: a study of immunostaining and multiple fluorescent tract tracing. J Comp Neurol. 2012;520:6-33 pubmed publisher
Stetzik L, Sullivan A, Patisaul H, Cushing B. Novel unconditioned prosocial behavior in prairie voles (Microtus ochrogaster) as a model for empathy. BMC Res Notes. 2018;11:852 pubmed publisher
Zhang B, Nakata M, Nakae J, Ogawa W, Yada T. Central insulin action induces activation of paraventricular oxytocin neurons to release oxytocin into circulation. Sci Rep. 2018;8:10415 pubmed publisher
V r y H, Adori C, Legrand R, Lucas N, Breton J, Cottard C, et al. Autoantibodies reactive to adrenocorticotropic hormone can alter cortisol secretion in both aggressive and nonaggressive humans. Proc Natl Acad Sci U S A. 2018;115:E6576-E6584 pubmed publisher
Choe H, Reed M, Benavidez N, Montgomery D, Soares N, Yim Y, et al. Oxytocin Mediates Entrainment of Sensory Stimuli to Social Cues of Opposing Valence. Neuron. 2015;87:152-63 pubmed publisher
Yao P, Kang D, Wang X, Lin R, Ye Z. Cell-density-dependent manifestation of partial characteristics for neuronal precursors in a newly established human gliosarcoma cell line. In Vitro Cell Dev Biol Anim. 2015;51:345-52 pubmed publisher
Sullivan A, Beach E, Stetzik L, Perry A, D Addezio A, Cushing B, et al. A novel model for neuroendocrine toxicology: neurobehavioral effects of BPA exposure in a prosocial species, the prairie vole (Microtus ochrogaster). Endocrinology. 2014;155:3867-81 pubmed publisher
Yao S, Gouraud S, Qiu J, Cunningham J, Paton J, Murphy D. Selective up-regulation of JunD transcript and protein expression in vasopressinergic supraoptic nucleus neurones in water-deprived rats. J Neuroendocrinol. 2012;24:1542-52 pubmed publisher
Xi D, Gandhi N, Lai M, Kublaoui B. Ablation of Sim1 neurons causes obesity through hyperphagia and reduced energy expenditure. PLoS ONE. 2012;7:e36453 pubmed publisher
Adewale H, Todd K, Mickens J, Patisaul H. The impact of neonatal bisphenol-A exposure on sexually dimorphic hypothalamic nuclei in the female rat. Neurotoxicology. 2011;32:38-49 pubmed publisher
Irani B, Donato J, Olson D, Lowell B, Sacktor T, Reyland M, et al. Distribution and neurochemical characterization of protein kinase C-theta and -delta in the rodent hypothalamus. Neuroscience. 2010;170:1065-79 pubmed publisher
Gelez H, Poirier S, Facchinetti P, Allers K, Wayman C, Alexandre L, et al. Neuroanatomical evidence for a role of central melanocortin-4 receptors and oxytocin in the efferent control of the rodent clitoris and vagina. J Sex Med. 2010;7:2056-2067 pubmed publisher
Shahrokh D, Zhang T, Diorio J, Gratton A, Meaney M. Oxytocin-dopamine interactions mediate variations in maternal behavior in the rat. Endocrinology. 2010;151:2276-86 pubmed publisher
Yuan H, Gao B, Duan L, Jiang S, Cao R, Xiong Y, et al. Acute hyperosmotic stimulus-induced Fos expression in neurons depends on activation of astrocytes in the supraoptic nucleus of rats. J Neurosci Res. 2010;88:1364-73 pubmed publisher
Papanikolaou T, Amano T, Lennington J, Sink K, Farrar A, Salamone J, et al. In-vitro analysis of Pitx3 in mesodiencephalic dopaminergic neuron maturation. Eur J Neurosci. 2009;29:2264-75 pubmed publisher
Kublaoui B, Gemelli T, Tolson K, Wang Y, Zinn A. Oxytocin deficiency mediates hyperphagic obesity of Sim1 haploinsufficient mice. Mol Endocrinol. 2008;22:1723-34 pubmed publisher
Kohno D, Nakata M, Maejima Y, Shimizu H, Sedbazar U, Yoshida N, et al. Nesfatin-1 neurons in paraventricular and supraoptic nuclei of the rat hypothalamus coexpress oxytocin and vasopressin and are activated by refeeding. Endocrinology. 2008;149:1295-301 pubmed
Garcia Espinosa M, Wallin R, Hutson S, Sweatt A. Widespread neuronal expression of branched-chain aminotransferase in the CNS: implications for leucine/glutamate metabolism and for signaling by amino acids. J Neurochem. 2007;100:1458-68 pubmed
Ng Y, Brailoiu G, Dun S, Ling E, Yang J, Chang J, et al. Beacon immunoreactivity in the rat hypothalamus. J Neurosci Res. 2006;83:1106-17 pubmed
Shimada A, Satoh M, Chiba Y, Saitoh Y, Kawamura N, Keino H, et al. Highly selective localization of leukotriene C4 synthase in hypothalamic and extrahypothalamic vasopressin systems of mouse brain. Neuroscience. 2005;131:683-9 pubmed
product information
Catalog Number :
MAB5296
Subcategory :
Neuroscience
Product Name :
Anti-Oxytocin Antibody, clone 4G11
Product Type :
Antibodies
Clonality :
Monoclonal Antibody
Gene ID :
P01178
Host Name :
Mouse
Antigen :
Oxytocin
Clone :
4G11
Conjugate :
Ascites
Isotype :
IgG1
Product Description :
Anti-Oxytocin Antibody, clone 4G11
Cross Reactivity :
Human;Rat
Immunogen :
Oxytocin conjugated to thyroglobulin.
Specificity :
Recognizes Oxytocin. No reactivity to arginine vasopressin, vasotocin or [Asu1,6,Arg8]-vasopressin by competitive ELISA.
Package Size :
100 μL
Uses :
ELISA;Immunohistochemistry
Storage :
Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
company information
EMD Millipore
290 Concord Road
Billerica, Massachusetts 01821
bioscienceshelp@emdchemical.com
https://www.emdmillipore.com
888-854-3417
headquarters: United States
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

Hundreds of New Antibodies in the areas of:
  • • Cancer
  • • Nuclear Signaling
  • • Apoptosis
  • • Cardiovascular Disease
  • • Developmental Biology
  • • Metabolic Disease
  • • Neurodegenerative Disease
  • • Cell Biology
View all the new antibodies at www.emdmillipore.com.