Nerve Growth Factor Antibody, clone 27/21 | EMD Millipore MAB5260-60UG product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Nerve Growth Factor Antibody, clone 27/21

catalog :

MAB5260-60UG

quantity :

60 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

27/21

reactivity :

human

citations: 1

Reference
Schnitzler A, Mellott T, Lopez Coviella I, Tallini Y, Kotlikoff M, Follettie M, et al. BMP9 (bone morphogenetic protein 9) induces NGF as an autocrine/paracrine cholinergic trophic factor in developing basal forebrain neurons. J Neurosci. 2010;30:8221-8 pubmed publisher

product information

Catalog Number :

MAB5260-60UG

Subcategory :

Neuroscience

Product Name :

Anti-Nerve Growth Factor Antibody, clone 27/21

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P20783

Host Name :

Mouse

Antigen :

Nerve Growth Factor

Clone :

27/21

Conjugate :

Purified

Isotype :

IgG1

Product Description :

Anti-Nerve Growth Factor Antibody, clone 27/21

Cross Reactivity :

Bovine;Human;Mouse;Rat

ALT Names :

NGF

Immunogen :

2.5 S form of mouse NGF.

Specificity :

NGF is a neurotrophic protein which is synthesized by the target tissues of NGF-sensitive neurons. NGF acts on sympathetic and sensoric neurons as well as on cholinergic neurons of the basal forebrain. It has been suggested that NGF is involved in the neuropathology of Alzheimer's Disease (Hefti & Weiner, 1986). In the peripheral nervous system, NGF plays a role in the development of autonomic and sensory neuropathies (Anand et al., 1991). The antibody specifically reacts with the beta -subunit of NGF from mouse, in the 2.5S- as well as in the 7S-form. The cross-reactivity with human NGF is 60-90 % of the reactivity with mouse NGF

Package Size :

60 µg

Uses :

ELISA

Storage :

The lyophilized antibody is stable if stored dry at 2-8°C for up to 12 months. After reconstitution maintain at 4°C unaliquotted but sealed tightly for 6 months; do not freeze thaw.