Epithelial Cell Adhesion Molecule (EpCAM) Antibody, clone 8 | EMD Millipore MAB4444 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Epithelial Cell Adhesion Molecule (EpCAM) Antibody, clone 8

catalog :

MAB4444

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

mab 8

reactivity :

human

application :

western blot, immunocytochemistry, flow cytometry

citations: 2

Reference
Libby A, Joy D, So P, Mandegar M, Muncie J, Mendoza Camacho F, et al. Spatiotemporal mosaic self-patterning of pluripotent stem cells using CRISPR interference. elife. 2018;7: pubmed publisher
Suffert G, Malterer G, Hausser J, Viiliäinen J, Fender A, Contrant M, et al. Kaposi's sarcoma herpesvirus microRNAs target caspase 3 and regulate apoptosis. PLoS Pathog. 2011;7:e1002405 pubmed publisher

product information

Catalog Number :

MAB4444

Subcategory :

Stem Cell Research

Product Name :

Anti-Epithelial Cell Adhesion Molecule (EpCAM) Antibody, clone 8

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P16422

Host Name :

Mouse

Antigen :

Epithelial Cell Adhesion Molecule (EpCAM)

Clone :

mab 8

Conjugate :

Purified

Isotype :

IgG2aκ

Product Description :

Anti-Epithelial Cell Adhesion Molecule (EpCAM) Antibody, clone 8

Cross Reactivity :

Human

Background :

Epithelial Call Adhesion Molecule (EpCAM, CD326) is a transmembrane glycoprotein of approximately 40 kDa. EpCAM was initially identified as a tumor associated marker having high expression in quickly proliferating epithelial tumors. As such, EpCAM has been of significant interest as a means for tumor diagnosis and therapy. EpCAM is also expressed in normal epithelial cells, but in comparatively lower levels. Preliminary studies limited EpCAM’s function to cell-cell adhesion; however more recent studies indicate it to be involved in diverse processes that include cell migration, cell signaling, differentiation and proliferation.

ALT Names :

Adenocarcinoma-associated antigen;CD326 antigen;Cell surface glycoprotein Trop-1;Epithelial cell surface antigen;Epithelial glycoprotein;KS 1/4 antigen;Major gastrointestinal tumor-associated protein GA733-2;antigen identified by monoclonal antibody AUA1;carcinoma-associated antigen GA733-2;epithelial cell adhesion molecule;human epithelial glycoprotein-2;membrane component, chromosome 4, surface marker (35kD glycoprotein);tumor-associated calcium signal transducer 1

Immunogen :

HES-3 Cells (Choo, et al. (2008) Stem Cells. Jun;26(6):1454-63)

Specificity :

This antibody recognizes epithelial cell adhesion molecule (EpCAM), specifically on undifferentiated human embryonic stem cells.

Package Size :

100 μg

Uses :

Flow Cytometry;Immunocytochemistry;Western Blotting

Storage :

Stable for 1 year at 2-8°C from date of receipt