OCT-4 [POU5F1] Antibody, clone 7F9.2, Alexa Fluor® 488 conjugate | EMD Millipore MAB4419A4 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

OCT-4 [POU5F1] Antibody, clone 7F9.2, Alexa Fluor® 488 conjugate

catalog :

MAB4419A4

quantity :

100 µL

clonality :

monoclonal

host :

mouse

conjugate :

AF488

clone name :

7F9.2

reactivity :

human, mouse

application :

immunocytochemistry

citations: 2

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; 1:1000; fig 4a	Cheng T, Zhai K, Chang Y, Yao G, He J, Wang F, et al. CHIR99021 combined with retinoic acid promotes the differentiation of primordial germ cells from human embryonic stem cells. Oncotarget. 2017;8:7814-7826 pubmed publisher
	Qi Q, Ding C, Hong P, Yang G, Xie Y, Wang J, et al. X chromosome inactivation in human parthenogenetic embryonic stem cells following prolonged passaging. Int J Mol Med. 2015;35:569-78 pubmed publisher

product information

Catalog Number :

MAB4419A4

Subcategory :

Stem Cell Research

Product Name :

Anti-OCT-4 [POU5F1] Antibody, clone 7F9.2, Alexa Fluor® 488 conjugate

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P20263

Host Name :

Mouse

Antigen :

OCT-4 [POU5F1]

Conjugate :

AlexaFluor®488

Isotype :

IgG1

Product Description :

Anti-OCT-4 [POU5F1] Antibody, clone 7F9.2, Alexa Fluor® 488 conjugate

Cross Reactivity :

Human;Mouse

Background :

Octamer-4 (Oct-4), a member of the POU family of transcription factors, has been demonstrated to be vital for the formation of self-renewing pluripotent stem cells. During embryogenesis, expression of Oct-4 is limited to pluripotent cells of the inner cell mass (ICM) that contribute to the formation of all fetal cell types. This relationship between Oct-4 and pluripotency has seen this transcription factor emerge as a marker of pluripotent stem cells. Undifferentiated human and murine pluripotent Embryonic Stem (ES) and Embryonic Carcinoma (EC) cells express Oct-4. Additionally, murine Embryonic Germ (EG) cells are also known to express Oct-4. Following stem cell differentiation, the level of Oct-4 expression decreases. Oct-4 has been identified as one of the main transcription factors required to reprogram somatic cells into induced pluripotent stem cells (iPS cells).

ALT Names :

Octamer-binding transcription factor 3;POU class 5 homeobox 1;POU domain class 5, transcription factor 1;POU-type homeodomain-containing DNA-binding protein;octamer-binding transcription factor-3;OCT3/4

Immunogen :

Recombinant human Oct-4 protein, aa 1-145

Specificity :

This antibody recognizes human and mouse Oct-4.

Package Size :

100 µL

Uses :

Immunocytochemistry

Storage :

Maintain refrigerated at 2-8ºC protected from light in undiluted aliquots for up to 6 months from date of receipt.