Oct-4 Antibody, clone 10H11.2, Alexa Fluor® 488 conjugate | EMD Millipore MAB4401A4 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Oct-4 Antibody, clone 10H11.2, Alexa Fluor® 488 conjugate

catalog :

MAB4401A4

quantity :

100 µL

clonality :

monoclonal

host :

mouse

conjugate :

AF488

clone name :

10H11.2

reactivity :

human

application :

immunocytochemistry

product information

Catalog Number :

MAB4401A4

Subcategory :

Stem Cell Research

Product Name :

Anti-Oct-4 Antibody, clone 10H11.2, Alexa Fluor® 488 conjugate

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

Q01860

Host Name :

Mouse

Antigen :

Oct 4

Conjugate :

AlexaFluor®488

Isotype :

IgG1

Product Description :

Anti-Oct-4 Antibody, clone 10H11.2, Alexa Fluor® 488 conjugate

Cross Reactivity :

Human

Background :

Octamer-4 (Oct-4), a member of the POU family of transcription factors, has been demonstrated to be vital for the formation of self-renewing pluripotent stem cells. During embryogenesis expression of Oct-4 is limited to pluripotent cells of the inner cell mass (ICM) that contribute to the formation of all fetal cell types. This relationship between Oct-4 and pluripotency has seen this transcription factor emerge as a marker of pluripotent stem cells. Undifferentiated human and murine pluripotent Embryonic Stem (ES) and Embryonic Carcinoma (EC) cells express Oct-4. Additionally, murine Embryonic Germ (EG) cells are also known to express Oct-4. Following stem cell differentiation, the level of Oct-4 expression decreases. Oct-4 has been indentified as one of the key genes used to reprogram somatic cells into induced pluripotent stem cells (iPS cells).

ALT Names :

OCT3/4;Octamer-binding transcription factor 3;POU class 5 homeobox 1;POU domain, class 5, transcription factor 1;POU-type homeodomain-containing DNA-binding protein;octamer-binding transcription factor-3

Immunogen :

Recombinant GST fusion protein, human Oct-4 (aa 1-134).

Specificity :

This antibody recognizes human Oct-4. Antibody is not reactive with mouse Oct-4 protein.

Package Size :

100 µL

Uses :

Immunocytochemistry

Storage :

Maintain refrigerated at 2-8ºC protected from light in undiluted aliquots for up to 6 months from date of receipt.