This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
EMD Millipore
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
product type :
antibody
product name :
TRA-1-81 Antibody, clone TRA-1-81
catalog :
MAB4381
quantity :
100 μg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
TRA-1-81

The same clone is also sold as:
reactivity :
African green monkey, human, dogs, pigs
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
citations: 139
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; loading ...; fig s4
Nickolls A, Lee M, Espinoza D, Szczot M, Lam R, Wang Q, et al. Transcriptional Programming of Human Mechanosensory Neuron Subtypes from Pluripotent Stem Cells. Cell Rep. 2020;30:932-946.e7 pubmed publisher
  • immunocytochemistry; human; 1:500; loading ...; fig 1e
Schuster S, Saravanakumar S, Schols L, Hauser S. Generation of a homozygous CRISPR/Cas9-mediated knockout human iPSC line for the STUB1 locus. Stem Cell Res. 2019;34:101378 pubmed publisher
  • immunocytochemistry; human; loading ...; fig s9d
Wang C, Najm R, Xu Q, Jeong D, Walker D, Balestra M, et al. Gain of toxic apolipoprotein E4 effects in human iPSC-derived neurons is ameliorated by a small-molecule structure corrector. Nat Med. 2018;24:647-657 pubmed publisher
  • immunocytochemistry; human; 1:400; loading ...; fig 1s3b
Matson J, Dumitru R, Coryell P, Baxley R, Chen W, Twaroski K, et al. Rapid DNA replication origin licensing protects stem cell pluripotency. elife. 2017;6: pubmed publisher
  • immunocytochemistry; human; 1:200; fig 1g
Alonso Barroso E, Brasil S, Briso Montiano Á, Navarrete R, Perez Cerda C, Ugarte M, et al. Generation and characterization of a human iPSC line from a patient with propionic acidemia due to defects in the PCCA gene. Stem Cell Res. 2017;23:173-177 pubmed publisher
  • immunocytochemistry; human; 1:100; loading ...; fig s1a
Jeziorowska D, Fontaine V, Jouve C, Villard E, Dussaud S, Akbar D, et al. Differential Sarcomere and Electrophysiological Maturation of Human iPSC-Derived Cardiac Myocytes in Monolayer vs. Aggregation-Based Differentiation Protocols. Int J Mol Sci. 2017;18: pubmed publisher
  • immunohistochemistry; human; 1:100; fig S2A
Geng Z, Walsh P, Truong V, Hill C, Ebeling M, Kapphahn R, et al. Generation of retinal pigmented epithelium from iPSCs derived from the conjunctiva of donors with and without age related macular degeneration. PLoS ONE. 2017;12:e0173575 pubmed publisher
  • immunocytochemistry; human; 1:500; loading ...; fig s1s
Hosoya M, Fujioka M, Sone T, Okamoto S, Akamatsu W, Ukai H, et al. Cochlear Cell Modeling Using Disease-Specific iPSCs Unveils a Degenerative Phenotype and Suggests Treatments for Congenital Progressive Hearing Loss. Cell Rep. 2017;18:68-81 pubmed publisher
  • immunocytochemistry; human; loading ...; tbl 1
Ang Y, Rivas R, Ribeiro A, Srivas R, Rivera J, Stone N, et al. Disease Model of GATA4 Mutation Reveals Transcription Factor Cooperativity in Human Cardiogenesis. Cell. 2016;167:1734-1749.e22 pubmed publisher
  • immunocytochemistry; human; 1:150; fig s1b
Gong L, Pan X, Chen H, Rao L, Zeng Y, Hang H, et al. p53 isoform Δ133p53 promotes efficiency of induced pluripotent stem cells and ensures genomic integrity during reprogramming. Sci Rep. 2016;6:37281 pubmed publisher
  • immunocytochemistry; human; 1:200; fig 1
Okata S, Yuasa S, Suzuki T, Ito S, Makita N, Yoshida T, et al. Embryonic type Na+ channel ?-subunit, SCN3B masks the disease phenotype of Brugada syndrome. Sci Rep. 2016;6:34198 pubmed publisher
  • immunocytochemistry; human; 1:500; fig s2
Borgs L, Peyre E, Alix P, Hanon K, Grobarczyk B, Godin J, et al. Dopaminergic neurons differentiating from LRRK2 G2019S induced pluripotent stem cells show early neuritic branching defects. Sci Rep. 2016;6:33377 pubmed publisher
  • immunocytochemistry; human; 1:200; loading ...; tbl 1
Vega Crespo A, Truong B, Hermann K, Awe J, Chang K, Lee P, et al. Investigating the functionality of an OCT4-short response element in human induced pluripotent stem cells. Mol Ther Methods Clin Dev. 2016;3:16050 pubmed publisher
  • immunocytochemistry; human; 1:1000; fig s5
Wiley L, Burnight E, DeLuca A, Anfinson K, Cranston C, Kaalberg E, et al. cGMP production of patient-specific iPSCs and photoreceptor precursor cells to treat retinal degenerative blindness. Sci Rep. 2016;6:30742 pubmed publisher
  • immunocytochemistry; human; fig 4
Pijuan Galitó S, Tamm C, Schuster J, Sobol M, Forsberg L, Merry C, et al. Human serum-derived protein removes the need for coating in defined human pluripotent stem cell culture. Nat Commun. 2016;7:12170 pubmed publisher
  • immunocytochemistry; human; 1:100; fig 1
Son M, Lee M, Jeon H, Seol B, Kim J, Chang J, et al. Generation and characterization of integration-free induced pluripotent stem cells from patients with autoimmune disease. Exp Mol Med. 2016;48:e232 pubmed publisher
  • immunocytochemistry; pigs ; 1:100; fig 2
  • immunocytochemistry; human; 1:100; fig s1
Hou D, Jin Y, Nie X, Zhang M, Ta N, Zhao L, et al. Derivation of Porcine Embryonic Stem-Like Cells from In Vitro-Produced Blastocyst-Stage Embryos. Sci Rep. 2016;6:25838 pubmed publisher
  • flow cytometry; human; fig s1
Li D, Wang L, Hou J, Shen Q, Chen Q, Wang X, et al. Optimized Approaches for Generation of Integration-free iPSCs from Human Urine-Derived Cells with Small Molecules and Autologous Feeder. Stem Cell Reports. 2016;6:717-728 pubmed publisher
  • immunocytochemistry; human; 1:500; fig S1B
Stratigopoulos G, Burnett L, Rausch R, Gill R, Penn D, Skowronski A, et al. Hypomorphism of Fto and Rpgrip1l causes obesity in mice. J Clin Invest. 2016;126:1897-910 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 2g
Saito H, Okita K, Fusaki N, Sabel M, Chang A, Ito F. Reprogramming of Melanoma Tumor-Infiltrating Lymphocytes to Induced Pluripotent Stem Cells. Stem Cells Int. 2016;2016:8394960 pubmed publisher
  • immunocytochemistry; human; 1:100; fig s2a
Shao Z, Zhang R, Khodadadi Jamayran A, Chen B, Crowley M, Festok M, et al. The acetyllysine reader BRD3R promotes human nuclear reprogramming and regulates mitosis. Nat Commun. 2016;7:10869 pubmed publisher
  • immunocytochemistry; human; fig 1b
Lin H, Masaki H, Yamaguchi T, Wada T, Yachie A, Nishimura K, et al. An assessment of the effects of ectopic gp91phox expression in XCGD iPSC-derived neutrophils. Mol Ther Methods Clin Dev. 2015;2:15046 pubmed publisher
  • western blot; human; 1:500; fig s5
Freedman B, Brooks C, Lam A, Fu H, Morizane R, Agrawal V, et al. Modelling kidney disease with CRISPR-mutant kidney organoids derived from human pluripotent epiblast spheroids. Nat Commun. 2015;6:8715 pubmed publisher
  • immunocytochemistry; African green monkey; 1:100; fig 1
Ramaswamy K, Yik W, Wang X, Oliphant E, Lu W, Shibata D, et al. Derivation of induced pluripotent stem cells from orangutan skin fibroblasts. BMC Res Notes. 2015;8:577 pubmed publisher
  • immunocytochemistry; human; 1:100; fig 5
Chen H, Aksoy I, Gonnot F, Osteil P, Aubry M, Hamela C, et al. Reinforcement of STAT3 activity reprogrammes human embryonic stem cells to naive-like pluripotency. Nat Commun. 2015;6:7095 pubmed publisher
  • immunocytochemistry; human; 1:100
Pino Barrio M, García García E, Menéndez P, Martínez Serrano A. V-myc immortalizes human neural stem cells in the absence of pluripotency-associated traits. PLoS ONE. 2015;10:e0118499 pubmed publisher
  • immunocytochemistry; human; 1:100; fig 3
Sanz Garcia A, Stojkovic M, Escobedo Lucea C. Growth of Human Pluripotent Stem Cells Using Functional Human Extracellular Matrix. Methods Mol Biol. 2016;1307:39-60 pubmed publisher
  • immunocytochemistry; human; 1:250
Diecke S, Lisowski L, Kooreman N, Wu J. Second generation codon optimized minicircle (CoMiC) for nonviral reprogramming of human adult fibroblasts. Methods Mol Biol. 2014;1181:1-13 pubmed publisher
  • immunohistochemistry - paraffin section; pigs ; 1:100
  • flow cytometry; pigs ; 1:100
Park M, Park J, Kim M, Lee K, Park H, Yun J, et al. Development of a high-yield technique to isolate spermatogonial stem cells from porcine testes. J Assist Reprod Genet. 2014;31:983-91 pubmed publisher
  • immunocytochemistry; human; 1:250; fig 1
Yu D, Swaroop M, Wang M, Baxa U, Yang R, Yan Y, et al. Niemann-Pick Disease Type C: Induced Pluripotent Stem Cell-Derived Neuronal Cells for Modeling Neural Disease and Evaluating Drug Efficacy. J Biomol Screen. 2014;19:1164-73 pubmed publisher
  • western blot; pigs ; 1:200
Uh K, Park C, Choi K, Park J, Jeong Y, Roh S, et al. Analysis of imprinted IGF2/H19 gene methylation and expression in normal fertilized and parthenogenetic embryonic stem cells of pigs. Anim Reprod Sci. 2014;147:47-55 pubmed publisher
  • immunocytochemistry; human
Ghaedi M, Mendez J, Bove P, Sivarapatna A, Raredon M, Niklason L. Alveolar epithelial differentiation of human induced pluripotent stem cells in a rotating bioreactor. Biomaterials. 2014;35:699-710 pubmed publisher
  • immunocytochemistry; dogs
Tobias I, Brooks C, Teichroeb J, Betts D. Derivation and culture of canine embryonic stem cells. Methods Mol Biol. 2013;1074:69-83 pubmed publisher
  • immunocytochemistry; pigs ; 1:50
Park K, Cha S, Ahn C, Woo H. Generation of porcine induced pluripotent stem cells and evaluation of their major histocompatibility complex protein expression in vitro. Vet Res Commun. 2013;37:293-301 pubmed publisher
  • immunocytochemistry; human; 1:100
Sharma A, Diecke S, Zhang W, Lan F, He C, Mordwinkin N, et al. The role of SIRT6 protein in aging and reprogramming of human induced pluripotent stem cells. J Biol Chem. 2013;288:18439-47 pubmed publisher
  • immunohistochemistry; human; 1:1000
Higurashi N, Uchida T, Lossin C, Misumi Y, Okada Y, Akamatsu W, et al. A human Dravet syndrome model from patient induced pluripotent stem cells. Mol Brain. 2013;6:19 pubmed publisher
  • immunocytochemistry; human
Yang S, Harnish E, Leeuw T, Dietz U, Batchelder E, Wright P, et al. Compound screening platform using human induced pluripotent stem cells to identify small molecules that promote chondrogenesis. Protein Cell. 2012;3:934-42 pubmed publisher
Varderidou Minasian S, Hinz L, Hagemans D, Posthuma D, Altelaar M, Heine V. Quantitative proteomic analysis of Rett iPSC-derived neuronal progenitors. Mol Autism. 2020;11:38 pubmed publisher
Gomez Giro G, Arias Fuenzalida J, Jarazo J, Zeuschner D, Ali M, Possemis N, et al. Synapse alterations precede neuronal damage and storage pathology in a human cerebral organoid model of CLN3-juvenile neuronal ceroid lipofuscinosis. Acta Neuropathol Commun. 2019;7:222 pubmed publisher
Jiang Y, Liu F, Zou F, Zhang Y, Wang B, Zhang Y, et al. PBX homeobox 1 enhances hair follicle mesenchymal stem cell proliferation and reprogramming through activation of the AKT/glycogen synthase kinase signaling pathway and suppression of apoptosis. Stem Cell Res Ther. 2019;10:268 pubmed publisher
Wang X, Sterr M, Ansarullah -, Burtscher I, Böttcher A, Beckenbauer J, et al. Point mutations in the PDX1 transactivation domain impair human β-cell development and function. Mol Metab. 2019;24:80-97 pubmed publisher
Meyer K, Feldman H, Lu T, Drake D, Lim E, Ling K, et al. REST and Neural Gene Network Dysregulation in iPSC Models of Alzheimer's Disease. Cell Rep. 2019;26:1112-1127.e9 pubmed publisher
Jeon H, Kim J, Choi J, Han E, Song C, Lee J, et al. Effects of the Extracts from Fruit and Stem of Camellia japonica on Induced Pluripotency and Wound Healing. J Clin Med. 2018;7: pubmed publisher
Li L, Roh J, Chang E, Lee Y, Lee S, Kim M, et al. iPSC Modeling of Presenilin1 Mutation in Alzheimer's Disease with Cerebellar Ataxia. Exp Neurobiol. 2018;27:350-364 pubmed publisher
Ding D, Chu T, Liu H. Dedifferentiation of human uterine polyp stem cells into embryo-like cells during inducing pluripotency. Int J Biol Sci. 2018;14:1586-1598 pubmed publisher
Wang S, Liu Z, Ye Y, Li B, Liu T, Zhang W, et al. Ectopic hTERT expression facilitates reprograming of fibroblasts derived from patients with Werner syndrome as a WS cellular model. Cell Death Dis. 2018;9:923 pubmed publisher
Liu J, Higgins C, Whitehouse J, Harris S, Crawford H, Christiano A, et al. Hair Follicle Dermal Cells Support Expansion of Murine and Human Embryonic and Induced Pluripotent Stem Cells and Promote Haematopoiesis in Mouse Cultures. Stem Cells Int. 2018;2018:8631432 pubmed publisher
Ferrer C, Alders M, Postma A, Park S, Klein M, Cetinbaş M, et al. An inactivating mutation in the histone deacetylase SIRT6 causes human perinatal lethality. Genes Dev. 2018;32:373-388 pubmed publisher
Chai S, Wan X, Ramirez Navarro A, Tesar P, Kaufman E, Ficker E, et al. Physiological genomics identifies genetic modifiers of long QT syndrome type 2 severity. J Clin Invest. 2018;128:1043-1056 pubmed publisher
Wang X, Sterr M, Burtscher I, Chen S, Hieronimus A, Machicao F, et al. Genome-wide analysis of PDX1 target genes in human pancreatic progenitors. Mol Metab. 2018;9:57-68 pubmed publisher
Li Y, Wang R, Qiao N, Peng G, Zhang K, Tang K, et al. Transcriptome analysis reveals determinant stages controlling human embryonic stem cell commitment to neuronal cells. J Biol Chem. 2017;292:19590-19604 pubmed publisher
Chen Z, Chang W, Etheridge A, Strickfaden H, Jin Z, Palidwor G, et al. Reprogramming progeria fibroblasts re-establishes a normal epigenetic landscape. Aging Cell. 2017;16:870-887 pubmed publisher
Teotia P, Sharma S, Airan B, Mohanty S. Feeder & basic fibroblast growth factor-free culture of human embryonic stem cells: Role of conditioned medium from immortalized human feeders. Indian J Med Res. 2016;144:838-851 pubmed publisher
Wang L, Zhang T, Wang L, Cai Y, Zhong X, He X, et al. Fatty acid synthesis is critical for stem cell pluripotency via promoting mitochondrial fission. EMBO J. 2017;36:1330-1347 pubmed publisher
Shimojima M, Yuasa S, Motoda C, Yozu G, Nagai T, Ito S, et al. Emerin plays a crucial role in nuclear invagination and in the nuclear calcium transient. Sci Rep. 2017;7:44312 pubmed publisher
Woo C, Maier V, Davey R, Brennan J, Li G, Brothers J, et al. Gene activation of SMN by selective disruption of lncRNA-mediated recruitment of PRC2 for the treatment of spinal muscular atrophy. Proc Natl Acad Sci U S A. 2017;114:E1509-E1518 pubmed publisher
Lorenz C, Lesimple P, Bukowiecki R, Zink A, Inak G, Mlody B, et al. Human iPSC-Derived Neural Progenitors Are an Effective Drug Discovery Model for Neurological mtDNA Disorders. Cell Stem Cell. 2017;20:659-674.e9 pubmed publisher
Zhu H, Behr B, Reddy V, Hughes M, Pan Y, Baker J. Human Embryonic Stem Cell Lines with Lesions in FOXP3 and NF1. PLoS ONE. 2016;11:e0151836 pubmed publisher
Lee H, Lee J, Park M, Hong Y, Marti H, Kim H, et al. Pathological roles of the VEGF/SphK pathway in Niemann-Pick type C neurons. Nat Commun. 2014;5:5514 pubmed publisher
Ichida J, TCW J, Williams L, Carter A, Shi Y, Moura M, et al. Notch inhibition allows oncogene-independent generation of iPS cells. Nat Chem Biol. 2014;10:632-639 pubmed publisher
Kishino Y, Seki T, Fujita J, Yuasa S, Tohyama S, Kunitomi A, et al. Derivation of transgene-free human induced pluripotent stem cells from human peripheral T cells in defined culture conditions. PLoS ONE. 2014;9:e97397 pubmed publisher
Whitworth D, Ovchinnikov D, Sun J, Fortuna P, Wolvetang E. Generation and characterization of leukemia inhibitory factor-dependent equine induced pluripotent stem cells from adult dermal fibroblasts. Stem Cells Dev. 2014;23:1515-23 pubmed publisher
Bershteyn M, Hayashi Y, Desachy G, Hsiao E, Sami S, Tsang K, et al. Cell-autonomous correction of ring chromosomes in human induced pluripotent stem cells. Nature. 2014;507:99-103 pubmed publisher
Tolar J, McGrath J, Xia L, Riddle M, Lees C, Eide C, et al. Patient-specific naturally gene-reverted induced pluripotent stem cells in recessive dystrophic epidermolysis bullosa. J Invest Dermatol. 2014;134:1246-1254 pubmed publisher
Cho Y, Han K, Kim D, Lee J, Lee S, Choi K, et al. Autophagy regulates homeostasis of pluripotency-associated proteins in hESCs. Stem Cells. 2014;32:424-35 pubmed publisher
Marchetto M, Narvaiza I, Denli A, Benner C, Lazzarini T, Nathanson J, et al. Differential L1 regulation in pluripotent stem cells of humans and apes. Nature. 2013;503:525-529 pubmed publisher
Zhang Z, Almeida S, Lu Y, Nishimura A, Peng L, Sun D, et al. Downregulation of microRNA-9 in iPSC-derived neurons of FTD/ALS patients with TDP-43 mutations. PLoS ONE. 2013;8:e76055 pubmed publisher
Tilgner K, Neganova I, Moreno Gimeno I, Al Aama J, Burks D, Yung S, et al. A human iPSC model of Ligase IV deficiency reveals an important role for NHEJ-mediated-DSB repair in the survival and genomic stability of induced pluripotent stem cells and emerging haematopoietic progenitors. Cell Death Differ. 2013;20:1089-100 pubmed publisher
Rassouli H, Tabe Bordbar M, Rezaei Larijani M, Pakzad M, Baharvand H, Salekdeh G. Cloning, expression and functional characterization of in-house prepared human basic fibroblast growth factor. Cell J. 2013;14:282-91 pubmed
Park J, Kim H, Uh K, Choi K, Kim H, Lee T, et al. Primed pluripotent cell lines derived from various embryonic origins and somatic cells in pig. PLoS ONE. 2013;8:e52481 pubmed publisher
Chang W, Lavoie J, Kwon S, Chen Z, Manias J, Behbahani J, et al. Feeder-independent derivation of induced-pluripotent stem cells from peripheral blood endothelial progenitor cells. Stem Cell Res. 2013;10:195-202 pubmed publisher
Puttonen K, Ruponen M, Kauppinen R, Wojciechowski S, Hovatta O, Koistinaho J. Improved method of producing human neural progenitor cells of high purity and in large quantities from pluripotent stem cells for transplantation studies. Cell Transplant. 2013;22:1753-66 pubmed publisher
Gropp M, Shilo V, Vainer G, Gov M, Gil Y, Khaner H, et al. Standardization of the teratoma assay for analysis of pluripotency of human ES cells and biosafety of their differentiated progeny. PLoS ONE. 2012;7:e45532 pubmed publisher
Ovchinnikov D, Turner J, Titmarsh D, Thakar N, Sin D, Cooper White J, et al. Generation of a human embryonic stem cell line stably expressing high levels of the fluorescent protein mCherry. World J Stem Cells. 2012;4:71-9 pubmed
Egashira T, Yuasa S, Suzuki T, Aizawa Y, Yamakawa H, Matsuhashi T, et al. Disease characterization using LQTS-specific induced pluripotent stem cells. Cardiovasc Res. 2012;95:419-29 pubmed publisher
Jadaliha M, Lee H, Pakzad M, Fathi A, Jeong S, Cho S, et al. Quantitative proteomic analysis of human embryonic stem cell differentiation by 8-plex iTRAQ labelling. PLoS ONE. 2012;7:e38532 pubmed publisher
Stephenson E, Jacquet L, Miere C, Wood V, Kadeva N, Cornwell G, et al. Derivation and propagation of human embryonic stem cell lines from frozen embryos in an animal product-free environment. Nat Protoc. 2012;7:1366-81 pubmed publisher
Shimojima K, Inoue T, Imai Y, Arai Y, Komoike Y, Sugawara M, et al. Reduced PLP1 expression in induced pluripotent stem cells derived from a Pelizaeus-Merzbacher disease patient with a partial PLP1 duplication. J Hum Genet. 2012;57:580-6 pubmed publisher
Pfaff N, Moritz T, Thum T, Cantz T. miRNAs involved in the generation, maintenance, and differentiation of pluripotent cells. J Mol Med (Berl). 2012;90:747-52 pubmed publisher
Montserrat N, Ramirez Bajo M, Xia Y, Sancho Martinez I, Moya Rull D, Miquel Serra L, et al. Generation of induced pluripotent stem cells from human renal proximal tubular cells with only two transcription factors, OCT4 and SOX2. J Biol Chem. 2012;287:24131-8 pubmed publisher
Khatau S, Kusuma S, Hanjaya Putra D, Mali P, Cheng L, Lee J, et al. The differential formation of the LINC-mediated perinuclear actin cap in pluripotent and somatic cells. PLoS ONE. 2012;7:e36689 pubmed publisher
Shetty R, Inamdar M. Derivation of human embryonic stem cell lines from poor quality embryos. Methods Mol Biol. 2012;873:151-61 pubmed publisher
Cao H, Yang P, Pu Y, Sun X, Yin H, Zhang Y, et al. Characterization of bovine induced pluripotent stem cells by lentiviral transduction of reprogramming factor fusion proteins. Int J Biol Sci. 2012;8:498-511 pubmed publisher
Sánchez Danés A, Richaud Patin Y, Carballo Carbajal I, Jimenez Delgado S, Caig C, Mora S, et al. Disease-specific phenotypes in dopamine neurons from human iPS-based models of genetic and sporadic Parkinson's disease. EMBO Mol Med. 2012;4:380-95 pubmed publisher
Whitworth D, Ovchinnikov D, Wolvetang E. Generation and characterization of LIF-dependent canine induced pluripotent stem cells from adult dermal fibroblasts. Stem Cells Dev. 2012;21:2288-97 pubmed publisher
Schinzel R, Ahfeldt T, Lau F, Lee Y, Cowley A, Shen T, et al. Efficient culturing and genetic manipulation of human pluripotent stem cells. PLoS ONE. 2011;6:e27495 pubmed publisher
Ananiev G, Williams E, Li H, Chang Q. Isogenic pairs of wild type and mutant induced pluripotent stem cell (iPSC) lines from Rett syndrome patients as in vitro disease model. PLoS ONE. 2011;6:e25255 pubmed publisher
Eguizabal C, Montserrat N, Vassena R, Barragan M, Garreta E, Garcia Quevedo L, et al. Complete meiosis from human induced pluripotent stem cells. Stem Cells. 2011;29:1186-95 pubmed publisher
Matsumura K, Bae J, Kim H, Hyon S. Effective vitrification of human induced pluripotent stem cells using carboxylated ?-poly-l-lysine. Cryobiology. 2011;63:76-83 pubmed publisher
Mtango N, Vandevoort C, Latham K. Ontological aspects of pluripotency and stemness gene expression pattern in the rhesus monkey. Gene Expr Patterns. 2011;11:285-98 pubmed publisher
Nishishita N, Ijiri H, Takenaka C, Kobayashi K, Goto K, Kotani E, et al. The use of leukemia inhibitory factor immobilized on virus-derived polyhedra to support the proliferation of mouse embryonic and induced pluripotent stem cells. Biomaterials. 2011;32:3555-63 pubmed publisher
Montserrat N, Garreta E, Gonzalez F, Gutiérrez J, Eguizabal C, Ramos V, et al. Simple generation of human induced pluripotent stem cells using poly-beta-amino esters as the non-viral gene delivery system. J Biol Chem. 2011;286:12417-28 pubmed publisher
Larijani M, Seifinejad A, Pournasr B, Hajihoseini V, Hassani S, Totonchi M, et al. Long-term maintenance of undifferentiated human embryonic and induced pluripotent stem cells in suspension. Stem Cells Dev. 2011;20:1911-23 pubmed publisher
Guo J, Tecirlioglu R, Nguyen L, Koh K, Jenkin G, Trounson A. Reprogramming factors involved in hybrids and cybrids of human embryonic stem cells fused with hepatocytes. Cell Reprogram. 2010;12:529-41 pubmed publisher
Kunova M, Matulka K, Eiselleova L, Trckova P, Hampl A, Dvorak P. Development of humanized culture medium with plant-derived serum replacement for human pluripotent stem cells. Reprod Biomed Online. 2010;21:676-86 pubmed publisher
Ghodsizadeh A, Taei A, Totonchi M, Seifinejad A, Gourabi H, Pournasr B, et al. Generation of liver disease-specific induced pluripotent stem cells along with efficient differentiation to functional hepatocyte-like cells. Stem Cell Rev. 2010;6:622-32 pubmed publisher
Yang J, Liao C, Pang C, Huang L, Lin Y, Chen Y, et al. Directed differentiation into neural lineages and therapeutic potential of porcine embryonic stem cells in rat Parkinson's disease model. Cell Reprogram. 2010;12:447-61 pubmed publisher
Kim S, Kim J, Lee E, Jeong Y, Hossein M, Park S, et al. Establishment and characterization of embryonic stem-like cells from porcine somatic cell nuclear transfer blastocysts. Zygote. 2010;18:93-101 pubmed publisher
Mateizel I, Spits C, De Rycke M, Liebaers I, Sermon K. Derivation, culture, and characterization of VUB hESC lines. In Vitro Cell Dev Biol Anim. 2010;46:300-8 pubmed publisher
Jia F, Wilson K, Sun N, Gupta D, Huang M, Li Z, et al. A nonviral minicircle vector for deriving human iPS cells. Nat Methods. 2010;7:197-9 pubmed publisher
Nasrabadi D, Larijani M, Fathi A, Gourabi H, Dizaj A, Baharvand H, et al. Nuclear proteome analysis of monkey embryonic stem cells during differentiation. Stem Cell Rev. 2010;6:50-61 pubmed publisher
Armstrong L, Tilgner K, Saretzki G, Atkinson S, Stojkovic M, Moreno R, et al. Human induced pluripotent stem cell lines show stress defense mechanisms and mitochondrial regulation similar to those of human embryonic stem cells. Stem Cells. 2010;28:661-73 pubmed publisher
Pakzad M, Totonchi M, Taei A, Seifinejad A, Hassani S, Baharvand H. Presence of a ROCK inhibitor in extracellular matrix supports more undifferentiated growth of feeder-free human embryonic and induced pluripotent stem cells upon passaging. Stem Cell Rev. 2010;6:96-107 pubmed publisher
Shimozawa N, Nakamura S, Takahashi I, Hatori M, Sankai T. Characterization of a novel embryonic stem cell line from an ICSI-derived blastocyst in the African green monkey. Reproduction. 2010;139:565-73 pubmed publisher
Nakamura K, Salomonis N, Tomoda K, Yamanaka S, Conklin B. G(i)-coupled GPCR signaling controls the formation and organization of human pluripotent colonies. PLoS ONE. 2009;4:e7780 pubmed publisher
Takenaka C, Nishishita N, Takada N, Jakt L, Kawamata S. Effective generation of iPS cells from CD34+ cord blood cells by inhibition of p53. Exp Hematol. 2010;38:154-62 pubmed publisher
Seifinejad A, Taei A, Totonchi M, Vazirinasab H, Hassani S, Aghdami N, et al. Generation of human induced pluripotent stem cells from a Bombay individual: moving towards "universal-donor" red blood cells. Biochem Biophys Res Commun. 2010;391:329-34 pubmed publisher
Rodriguez Piza I, Richaud Patin Y, Vassena R, Gonzalez F, Barrero M, Veiga A, et al. Reprogramming of human fibroblasts to induced pluripotent stem cells under xeno-free conditions. Stem Cells. 2010;28:36-44 pubmed publisher
Totonchi M, Taei A, Seifinejad A, Tabebordbar M, Rassouli H, Farrokhi A, et al. Feeder- and serum-free establishment and expansion of human induced pluripotent stem cells. Int J Dev Biol. 2010;54:877-86 pubmed publisher
Fathi A, Pakzad M, Taei A, Brink T, Pirhaji L, Ruiz G, et al. Comparative proteome and transcriptome analyses of embryonic stem cells during embryoid body-based differentiation. Proteomics. 2009;9:4859-70 pubmed publisher
Byrne J, Nguyen H, Reijo Pera R. Enhanced generation of induced pluripotent stem cells from a subpopulation of human fibroblasts. PLoS ONE. 2009;4:e7118 pubmed publisher
Maehr R, Chen S, Snitow M, Ludwig T, Yagasaki L, Goland R, et al. Generation of pluripotent stem cells from patients with type 1 diabetes. Proc Natl Acad Sci U S A. 2009;106:15768-73 pubmed publisher
Geens M, Mateizel I, Sermon K, De Rycke M, Spits C, Cauffman G, et al. Human embryonic stem cell lines derived from single blastomeres of two 4-cell stage embryos. Hum Reprod. 2009;24:2709-17 pubmed publisher
Mollamohammadi S, Taei A, Pakzad M, Totonchi M, Seifinejad A, Masoudi N, et al. A simple and efficient cryopreservation method for feeder-free dissociated human induced pluripotent stem cells and human embryonic stem cells. Hum Reprod. 2009;24:2468-76 pubmed publisher
Mateizel I, Spits C, Verloes A, Mertzanidou A, Liebaers I, Sermon K. Characterization of CD30 expression in human embryonic stem cell lines cultured in serum-free media and passaged mechanically. Hum Reprod. 2009;24:2477-89 pubmed publisher
Makino H, Toyoda M, Matsumoto K, Saito H, Nishino K, Fukawatase Y, et al. Mesenchymal to embryonic incomplete transition of human cells by chimeric OCT4/3 (POU5F1) with physiological co-activator EWS. Exp Cell Res. 2009;315:2727-40 pubmed publisher
Papapetrou E, Tomishima M, Chambers S, Mica Y, Reed E, Menon J, et al. Stoichiometric and temporal requirements of Oct4, Sox2, Klf4, and c-Myc expression for efficient human iPSC induction and differentiation. Proc Natl Acad Sci U S A. 2009;106:12759-64 pubmed publisher
Yang J, Shiue Y, Liao C, Lin S, Chen L. Establishment and characterization of novel porcine embryonic stem cell lines expressing hrGFP. Cloning Stem Cells. 2009;11:235-44 pubmed publisher
Nasrabadi D, Rezaei Larijani M, Pirhaji L, Gourabi H, Shahverdi A, Baharvand H, et al. Proteomic analysis of monkey embryonic stem cell during differentiation. J Proteome Res. 2009;8:1527-39 pubmed publisher
Vaags A, Rosic Kablar S, Gartley C, Zheng Y, Chesney A, Villagómez D, et al. Derivation and characterization of canine embryonic stem cell lines with in vitro and in vivo differentiation potential. Stem Cells. 2009;27:329-40 pubmed publisher
Aasen T, Raya A, Barrero M, Garreta E, Consiglio A, Gonzalez F, et al. Efficient and rapid generation of induced pluripotent stem cells from human keratinocytes. Nat Biotechnol. 2008;26:1276-84 pubmed publisher
Hikita S, Kosik K, Clegg D, Bamdad C. MUC1* mediates the growth of human pluripotent stem cells. PLoS ONE. 2008;3:e3312 pubmed publisher
Maherali N, Ahfeldt T, Rigamonti A, Utikal J, Cowan C, Hochedlinger K. A high-efficiency system for the generation and study of human induced pluripotent stem cells. Cell Stem Cell. 2008;3:340-5 pubmed publisher
Pereira C, Terranova R, Ryan N, Santos J, Morris K, Cui W, et al. Heterokaryon-based reprogramming of human B lymphocytes for pluripotency requires Oct4 but not Sox2. PLoS Genet. 2008;4:e1000170 pubmed publisher
Phillips B, Horne R, Lay T, Rust W, Teck T, Crook J. Attachment and growth of human embryonic stem cells on microcarriers. J Biotechnol. 2008;138:24-32 pubmed publisher
Muller T, Eildermann K, Dhir R, Schlatt S, Behr R. Glycan stem-cell markers are specifically expressed by spermatogonia in the adult non-human primate testis. Hum Reprod. 2008;23:2292-8 pubmed publisher
Di Domenico A, Christodoulou I, Pells S, McWhir J, Thomson A. Sequential genetic modification of the hprt locus in human ESCs combining gene targeting and recombinase-mediated cassette exchange. Cloning Stem Cells. 2008;10:217-30 pubmed publisher
Rubio D, Garcia S, de la Cueva T, Paz M, Lloyd A, Bernad A, et al. Human mesenchymal stem cell transformation is associated with a mesenchymal-epithelial transition. Exp Cell Res. 2008;314:691-8 pubmed publisher
Hayes B, Fagerlie S, Ramakrishnan A, Baran S, Harkey M, Graf L, et al. Derivation, characterization, and in vitro differentiation of canine embryonic stem cells. Stem Cells. 2008;26:465-73 pubmed
Revazova E, Turovets N, Kochetkova O, Kindarova L, Kuzmichev L, Janus J, et al. Patient-specific stem cell lines derived from human parthenogenetic blastocysts. Cloning Stem Cells. 2007;9:432-49 pubmed
Miki T, Mitamura K, Ross M, Stolz D, Strom S. Identification of stem cell marker-positive cells by immunofluorescence in term human amnion. J Reprod Immunol. 2007;75:91-6 pubmed
Zhang Y, Denham J, Thies R. Oligodendrocyte progenitor cells derived from human embryonic stem cells express neurotrophic factors. Stem Cells Dev. 2006;15:943-52 pubmed
Sidhu K, Lie K, Tuch B. Transgenic human fetal fibroblasts as feeder layer for human embryonic stem cell lineage selection. Stem Cells Dev. 2006;15:741-7 pubmed
Dravid G, Hammond H, Cheng L. Culture of human embryonic stem cells on human and mouse feeder cells. Methods Mol Biol. 2006;331:91-104 pubmed
Mitalipova M, Palmarini G. Isolation and characterization of human embryonic stem cells. Methods Mol Biol. 2006;331:55-76 pubmed
Forsyth N, Musio A, Vezzoni P, Simpson A, Noble B, McWhir J. Physiologic oxygen enhances human embryonic stem cell clonal recovery and reduces chromosomal abnormalities. Cloning Stem Cells. 2006;8:16-23 pubmed
Rieske P, Krynska B, Azizi S. Human fibroblast-derived cell lines have characteristics of embryonic stem cells and cells of neuro-ectodermal origin. Differentiation. 2005;73:474-83 pubmed
Manzoor S, Elahi M. Embryonic stem cell biotechnology research and the ethics of derivation: safe step towards therapeutic cloning. J Coll Physicians Surg Pak. 2005;15:517 pubmed
Miki T, Lehmann T, Cai H, Stolz D, Strom S. Stem cell characteristics of amniotic epithelial cells. Stem Cells. 2005;23:1549-59 pubmed
product information
Catalog Number :
MAB4381
Subcategory :
Stem Cell Research
Product Name :
Anti-TRA-1-81 Antibody, clone TRA-1-81
Product Type :
Antibodies
Clonality :
Monoclonal Antibody
Host Name :
Mouse
Antigen :
TRA-1-81
Clone :
clone TRA-1-81
Conjugate :
Purified
Isotype :
IgM
Product Description :
Anti-TRA-1-81 Antibody, clone TRA-1-81
Cross Reactivity :
Human
Background :
Human embryonal carcinoma (EC) cells are the stem cells of teratocarcinomas, and they are key components of germ cell tumors (GCTs). Embryonal carcinoma, as do all human pluripotent stem cells, expresses TRA-1-60 and TRA-1-81 antigens, and although their molecular identities are unknown, they are commonly used as markers of undifferentiated pluripotent human stem cells.
Immunogen :
Human embryonal carcinoma cell line 2102Ep
Specificity :
This antibody reacts with TRA-1-81 antigen that is expressed upon the surface of human tetracarcinoma stem cells (EC), human embryonic germ cells (EG) and human embryonic stem cells (ES). No immunoreactivity is seen with murine EC, EG or ES cells. Both the TRA-1-81 and TRA-1-60 monoclonal antibodies (MAB4360) recognize antigens that are associated with a pericellular matrix proteoglycan. TRA-1-60 reacts with a sialidase-sensitive epitope whilst TRA-1-81 reacts with an unknown epitope of the same molecule.
Package Size :
100 μg
Uses :
Western Blotting;Flow Cytometry;Immunofluorescence;Immunoprecipitation;Immunocytochemistry
Storage :
Stable for 1 year at from date of receipt.
company information
EMD Millipore
290 Concord Road
Billerica, Massachusetts 01821
bioscienceshelp@emdchemical.com
https://www.emdmillipore.com
888-854-3417
headquarters: United States
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

Hundreds of New Antibodies in the areas of:
  • • Cancer
  • • Nuclear Signaling
  • • Apoptosis
  • • Cardiovascular Disease
  • • Developmental Biology
  • • Metabolic Disease
  • • Neurodegenerative Disease
  • • Cell Biology
View all the new antibodies at www.emdmillipore.com.