SNAI2 Antibody, clone 2B6 | EMD Millipore MAB4371 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

SNAI2 Antibody, clone 2B6

catalog :

MAB4371

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2B6

reactivity :

human

application :

western blot

citations: 2

Published Application/Species/Sample/Dilution	Reference
western blot; human	Azzi S, Gallerne C, Romei C, Le Coz V, Gangemi R, Khawam K, et al. Human Renal Normal, Tumoral, and Cancer Stem Cells Express Membrane-Bound Interleukin-15 Isoforms Displaying Different Functions. Neoplasia. 2015;17:509-17 pubmed publisher
	Katafiasz D, Smith L, Wahl J. Slug (SNAI2) expression in oral SCC cells results in altered cell-cell adhesion and increased motility. Cell Adh Migr. 2011;5:315-22 pubmed

product information

Catalog Number :

MAB4371

Subcategory :

Stem Cell Research

Product Name :

Anti-SNAI2 Antibody, clone 2B6

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

O43623

Host Name :

Mouse

Antigen :

SNAI2

Clone :

2B6

Conjugate :

Purified

Isotype :

IgG1κ

Product Description :

Anti-SNAI2 Antibody, clone 2B6

Cross Reactivity :

Human

Background :

SNAI2 (snail homolog 2) is a neurogenic transcription factor belonging to the SNAIL family and is implicated in both the epithelial-mesenchymal transition and cell survival, as well as in important morphogenetic processes during embryo development and tumor metastasis. Through studies done in chick embryo, this protein has also been identified in the neural crest and in mesodermal cells emigrating from the primitive streak. In addition, SNAI2 has been found to be a key contributor to the function of the stem cell factor/c-kit signaling pathway, and mediates the radioresistance biological function of SCF/c-kit. Consequently, alterations to this gene have been associated to different human syndromes. SNAI2 is predominately expressed in placenta, melanocytes, and differentiating embryonic stem cells, as well as in adult heart, pancreas, liver, kidney, skeletal muscle.

ALT Names :

Neural crest transcription factor Slug ;Protein snail homolog 2 ;slug (chicken homolog), zinc finger protein ;slug homolog, zinc finger protein ;slug homolog, zinc finger protein (chicken);snail 2;snail homolog 2 (Drosophila)

Immunogen :

Synthetic human SNAI2 peptide, a.a. 97-169.

Specificity :

This monoclonal antibody recognizes the SNAI2 protein.

Package Size :

100 μg

Uses :

Western Blotting

Storage :

Maintain refrigerated at 2-8°C in undiluted aliquots for up to 12 months. Avoid repeat freeze/thaw cycles.