SRF [Serum Response Factor] Antibody, clone 1E1 | EMD Millipore MAB4369 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

SRF [Serum Response Factor] Antibody, clone 1E1

catalog :

MAB4369

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1E1

The same clone is also sold as:

Abnova: H00006722-M03

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry

citations: 3

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:1000; fig 4	Liu H, Zhang S, Zhao L, Zhang Y, Li Q, Chai X, et al. Resveratrol Enhances Cardiomyocyte Differentiation of Human Induced Pluripotent Stem Cells through Inhibiting Canonical WNT Signal Pathway and Enhancing Serum Response Factor-miR-1 Axis. Stem Cells Int. 2016;2016:2524092 pubmed publisher
immunohistochemistry; human; 1:1000	Higurashi N, Uchida T, Lossin C, Misumi Y, Okada Y, Akamatsu W, et al. A human Dravet syndrome model from patient induced pluripotent stem cells. Mol Brain. 2013;6:19 pubmed publisher
	Booy E, Henson E, Gibson S. Epidermal growth factor regulates Mcl-1 expression through the MAPK-Elk-1 signalling pathway contributing to cell survival in breast cancer. Oncogene. 2011;30:2367-78 pubmed publisher

product information

Catalog Number :

MAB4369

Subcategory :

Stem Cell Research

Product Name :

Anti-SRF [Serum Response Factor] Antibody, clone 1E1

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P11831

Host Name :

Mouse

Antigen :

SRF [Serum Response Factor]

Clone :

1E1

Conjugate :

Purified

Isotype :

IgG1κ

Product Description :

Anti-SRF [Serum Response Factor] Antibody, clone 1E1

Cross Reactivity :

Human;Mouse

Background :

Serum response factor (SRF) is a nuclear transcription factor that binds to the serum response element (SRE), and is essential for embryonic development of the mesoderm, as well as for the maintenance of adult muscle cells and neurons. As this protein is involved in the downstream regulation of many immediate-early genes, it participates in a variety of cell functions, including cell cycle, apoptosis, cell growth, and cell differentiation. SRF is most commonly activated by serum, LPA, LPS, TPA, growth factors, including TNFalpha, as well as antioxidants and UV light.

ALT Names :

serum response factor (c-fos serum response element-binding transcription factor)

Immunogen :

Synthetic human SRF peptide, a.a. 406-508.

Specificity :

This monoclonal antibody recognizes SRF.

Package Size :

100 μg

Uses :

Western Blotting;Immunocytochemistry

Storage :

Maintain refrigerated at 2-8°C in undiluted aliquots for up to 12 months. Avoid repeat freeze/thaw cycles.