This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
EMD Millipore
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
product type :
antibody
product name :
TRA-1-60 Antibody, clone TRA-1-60
catalog :
MAB4360
quantity :
100 μg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
TRA-1-60
reactivity :
African green monkey, human, mouse, dogs, bovine, pigs , domestic rabbit, rhesus macaque
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, blocking or activating experiments, other
citations: 200
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; loading ...; fig s4
Nickolls A, Lee M, Espinoza D, Szczot M, Lam R, Wang Q, et al. Transcriptional Programming of Human Mechanosensory Neuron Subtypes from Pluripotent Stem Cells. Cell Rep. 2020;30:932-946.e7 pubmed publisher
  • flow cytometry; human; 1:50; loading ...; fig s2c, s4b
Yap L, Wang J, Moreno Moral A, Chong L, Sun Y, Harmston N, et al. In Vivo Generation of Post-infarct Human Cardiac Muscle by Laminin-Promoted Cardiovascular Progenitors. Cell Rep. 2019;26:3231-3245.e9 pubmed publisher
  • immunocytochemistry; human; 1:200; loading ...; fig 1e
Lü Y, Dong E, Yang W, Lai L, Lin X, Ma L, et al. Generation of an integration-free induced pluripotent stem cell line, FJMUi001-A, from a hereditary spastic paraplegia patient carrying compound heterozygous p.P498L and p.R618W mutations in CAPN1 (SPG76). Stem Cell Res. 2019;34:101354 pubmed publisher
  • immunocytochemistry; human; 1:100; loading ...; fig 1d
Klein T, Günther K, Kwok C, Edenhofer F, Uceyler N. Generation of the human induced pluripotent stem cell line (UKWNLi001-A) from skin fibroblasts of a woman with Fabry disease carrying the X-chromosomal heterozygous c.708 G > C (W236C) missense mutation in exon 5 of the alpha-galactosidase-A gene. Stem Cell Res. 2018;31:222-226 pubmed publisher
  • immunocytochemistry; human; loading ...; fig s1d
Wang C, Najm R, Xu Q, Jeong D, Walker D, Balestra M, et al. Gain of toxic apolipoprotein E4 effects in human iPSC-derived neurons is ameliorated by a small-molecule structure corrector. Nat Med. 2018;24:647-657 pubmed publisher
  • immunocytochemistry; human; 1:300; loading ...; fig 3a
Wu M, Liu S, Gao Y, Bai H, Machairaki V, Li G, et al. Conditional gene knockout and reconstitution in human iPSCs with an inducible Cas9 system. Stem Cell Res. 2018;29:6-14 pubmed publisher
  • immunocytochemistry; human; fig s2a
Aneichyk T, Hendriks W, Yadav R, Shin D, Gao D, Vaine C, et al. Dissecting the Causal Mechanism of X-Linked Dystonia-Parkinsonism by Integrating Genome and Transcriptome Assembly. Cell. 2018;172:897-909.e21 pubmed publisher
  • flow cytometry; human; loading ...; fig 1b
Cai L, Bai H, Mahairaki V, Gao Y, He C, Wen Y, et al. A Universal Approach to Correct Various HBB Gene Mutations in Human Stem Cells for Gene Therapy of Beta-Thalassemia and Sickle Cell Disease. Stem Cells Transl Med. 2018;7:87-97 pubmed publisher
  • immunocytochemistry; human; 1:400; loading ...; fig 1s3b
Matson J, Dumitru R, Coryell P, Baxley R, Chen W, Twaroski K, et al. Rapid DNA replication origin licensing protects stem cell pluripotency. elife. 2017;6: pubmed publisher
  • immunocytochemistry; human; 1:200; fig 1g
Alonso Barroso E, Brasil S, Briso Montiano Á, Navarrete R, Perez Cerda C, Ugarte M, et al. Generation and characterization of a human iPSC line from a patient with propionic acidemia due to defects in the PCCA gene. Stem Cell Res. 2017;23:173-177 pubmed publisher
  • immunocytochemistry; human; 1:100; loading ...; fig s1a
Jeziorowska D, Fontaine V, Jouve C, Villard E, Dussaud S, Akbar D, et al. Differential Sarcomere and Electrophysiological Maturation of Human iPSC-Derived Cardiac Myocytes in Monolayer vs. Aggregation-Based Differentiation Protocols. Int J Mol Sci. 2017;18: pubmed publisher
  • immunocytochemistry; human; 1:500; loading ...; fig s1a
Cha Y, Han M, Cha H, Zoldan J, Burkart A, Jung J, et al. Metabolic control of primed human pluripotent stem cell fate and function by the miR-200c-SIRT2 axis. Nat Cell Biol. 2017;19:445-456 pubmed publisher
  • immunocytochemistry; human; 1:300; loading ...; tbl 1
Liu S, Ye Z, Gao Y, He C, Williams D, MOLITERNO A, et al. Generation of human iPSCs from an essential thrombocythemia patient carrying a V501L mutation in the MPL gene. Stem Cell Res. 2017;18:57-59 pubmed publisher
  • immunocytochemistry; human; 1:500; loading ...; fig s1p
Hosoya M, Fujioka M, Sone T, Okamoto S, Akamatsu W, Ukai H, et al. Cochlear Cell Modeling Using Disease-Specific iPSCs Unveils a Degenerative Phenotype and Suggests Treatments for Congenital Progressive Hearing Loss. Cell Rep. 2017;18:68-81 pubmed publisher
  • immunocytochemistry; human; loading ...; fig s1e
Ang Y, Rivas R, Ribeiro A, Srivas R, Rivera J, Stone N, et al. Disease Model of GATA4 Mutation Reveals Transcription Factor Cooperativity in Human Cardiogenesis. Cell. 2016;167:1734-1749.e22 pubmed publisher
  • immunocytochemistry; human; 1:150; fig s1b
Gong L, Pan X, Chen H, Rao L, Zeng Y, Hang H, et al. p53 isoform Δ133p53 promotes efficiency of induced pluripotent stem cells and ensures genomic integrity during reprogramming. Sci Rep. 2016;6:37281 pubmed publisher
  • immunocytochemistry; human; 1:200; fig 1
Okata S, Yuasa S, Suzuki T, Ito S, Makita N, Yoshida T, et al. Embryonic type Na+ channel ?-subunit, SCN3B masks the disease phenotype of Brugada syndrome. Sci Rep. 2016;6:34198 pubmed publisher
  • immunocytochemistry; human; 1:100; fig 4
Ahmadian Baghbaderani B, Tian X, Scotty Cadet J, Shah K, Walde A, Tran H, et al. A Newly Defined and Xeno-Free Culture Medium Supports Every-Other-Day Medium Replacement in the Generation and Long-Term Cultivation of Human Pluripotent Stem Cells. PLoS ONE. 2016;11:e0161229 pubmed publisher
  • immunocytochemistry; human; 1:200; loading ...; tbl 1
Vega Crespo A, Truong B, Hermann K, Awe J, Chang K, Lee P, et al. Investigating the functionality of an OCT4-short response element in human induced pluripotent stem cells. Mol Ther Methods Clin Dev. 2016;3:16050 pubmed publisher
  • immunocytochemistry; human; 1:1000; fig s5
Wiley L, Burnight E, DeLuca A, Anfinson K, Cranston C, Kaalberg E, et al. cGMP production of patient-specific iPSCs and photoreceptor precursor cells to treat retinal degenerative blindness. Sci Rep. 2016;6:30742 pubmed publisher
  • immunocytochemistry; human; fig s7
Pijuan Galitó S, Tamm C, Schuster J, Sobol M, Forsberg L, Merry C, et al. Human serum-derived protein removes the need for coating in defined human pluripotent stem cell culture. Nat Commun. 2016;7:12170 pubmed publisher
  • immunocytochemistry; human; 1:100; fig 1
Baghbaderani B, Syama A, Sivapatham R, Pei Y, Mukherjee O, Fellner T, et al. Detailed Characterization of Human Induced Pluripotent Stem Cells Manufactured for Therapeutic Applications. Stem Cell Rev. 2016;12:394-420 pubmed publisher
  • immunocytochemistry; human; 1:100; fig 1
Son M, Lee M, Jeon H, Seol B, Kim J, Chang J, et al. Generation and characterization of integration-free induced pluripotent stem cells from patients with autoimmune disease. Exp Mol Med. 2016;48:e232 pubmed publisher
  • immunocytochemistry; pigs ; 1:100; fig 2
  • immunocytochemistry; human; 1:100; fig s1
Hou D, Jin Y, Nie X, Zhang M, Ta N, Zhao L, et al. Derivation of Porcine Embryonic Stem-Like Cells from In Vitro-Produced Blastocyst-Stage Embryos. Sci Rep. 2016;6:25838 pubmed publisher
  • flow cytometry; human; fig s1
Li D, Wang L, Hou J, Shen Q, Chen Q, Wang X, et al. Optimized Approaches for Generation of Integration-free iPSCs from Human Urine-Derived Cells with Small Molecules and Autologous Feeder. Stem Cell Reports. 2016;6:717-728 pubmed publisher
  • immunocytochemistry; human; 1:500; fig S1B
Stratigopoulos G, Burnett L, Rausch R, Gill R, Penn D, Skowronski A, et al. Hypomorphism of Fto and Rpgrip1l causes obesity in mice. J Clin Invest. 2016;126:1897-910 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 2g
Saito H, Okita K, Fusaki N, Sabel M, Chang A, Ito F. Reprogramming of Melanoma Tumor-Infiltrating Lymphocytes to Induced Pluripotent Stem Cells. Stem Cells Int. 2016;2016:8394960 pubmed publisher
  • immunocytochemistry; human; 1:100; fig s2a
Shao Z, Zhang R, Khodadadi Jamayran A, Chen B, Crowley M, Festok M, et al. The acetyllysine reader BRD3R promotes human nuclear reprogramming and regulates mitosis. Nat Commun. 2016;7:10869 pubmed publisher
  • blocking or activating experiments; human; loading ...
Kang L, Yao C, Khodadadi Jamayran A, Xu W, Zhang R, Banerjee N, et al. The Universal 3D3 Antibody of Human PODXL Is Pluripotent Cytotoxic, and Identifies a Residual Population After Extended Differentiation of Pluripotent Stem Cells. Stem Cells Dev. 2016;25:556-68 pubmed publisher
  • immunocytochemistry; human; fig s1
Kyttälä A, Moraghebi R, Valensisi C, Kettunen J, Andrus C, Pasumarthy K, et al. Genetic Variability Overrides the Impact of Parental Cell Type and Determines iPSC Differentiation Potential. Stem Cell Reports. 2016;6:200-12 pubmed publisher
  • immunocytochemistry; human; fig 1b
Lin H, Masaki H, Yamaguchi T, Wada T, Yachie A, Nishimura K, et al. An assessment of the effects of ectopic gp91phox expression in XCGD iPSC-derived neutrophils. Mol Ther Methods Clin Dev. 2015;2:15046 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 1b
Lin L, Swerdel M, Lazaropoulos M, Hoffman G, Toro Ramos A, Wright J, et al. Spontaneous ATM Gene Reversion in A-T iPSC to Produce an Isogenic Cell Line. Stem Cell Reports. 2015;5:1097-1108 pubmed publisher
  • immunocytochemistry; human; 1:200; loading ...; tbl 1
Mikhailova A, Ilmarinen T, Ratnayake A, Petrovski G, Uusitalo H, Skottman H, et al. Human pluripotent stem cell-derived limbal epithelial stem cells on bioengineered matrices for corneal reconstruction. Exp Eye Res. 2016;146:26-34 pubmed publisher
  • immunocytochemistry; human; 1:500; fig 1
  • western blot; human; 1:500; fig s5
Freedman B, Brooks C, Lam A, Fu H, Morizane R, Agrawal V, et al. Modelling kidney disease with CRISPR-mutant kidney organoids derived from human pluripotent epiblast spheroids. Nat Commun. 2015;6:8715 pubmed publisher
  • immunocytochemistry; African green monkey; 1:100; fig 1
Ramaswamy K, Yik W, Wang X, Oliphant E, Lu W, Shibata D, et al. Derivation of induced pluripotent stem cells from orangutan skin fibroblasts. BMC Res Notes. 2015;8:577 pubmed publisher
  • immunocytochemistry; human; 5 ug/ml; loading ...; fig 3e
Hung S, Pébay A, Wong R. Generation of Integration-free Human Induced Pluripotent Stem Cells Using Hair-derived Keratinocytes. J Vis Exp. 2015;:e53174 pubmed publisher
  • immunocytochemistry; bovine; 1:200
Park S, Kim D, Jung Y, Roh S. Thiazovivin, a Rho kinase inhibitor, improves stemness maintenance of embryo-derived stem-like cells under chemically defined culture conditions in cattle. Anim Reprod Sci. 2015;161:47-57 pubmed publisher
  • immunocytochemistry; human; 1:300; fig s3
Alves C, Dariolli R, Jorge F, Monteiro M, Maximino J, Martins R, et al. Gene expression profiling for human iPS-derived motor neurons from sporadic ALS patients reveals a strong association between mitochondrial functions and neurodegeneration. Front Cell Neurosci. 2015;9:289 pubmed publisher
  • immunocytochemistry; human; tbl 2
Liu J, Brzeszczynska J, Samuel K, Black J, Palakkan A, Anderson R, et al. Efficient episomal reprogramming of blood mononuclear cells and differentiation to hepatocytes with functional drug metabolism. Exp Cell Res. 2015;338:203-13 pubmed publisher
  • flow cytometry; human
Huang X, Hu Q, Braun G, Pallaoro A, Morales D, ZASADZINSKI J, et al. Light-activated RNA interference in human embryonic stem cells. Biomaterials. 2015;63:70-9 pubmed publisher
  • immunocytochemistry; human; 1:100; fig 2
Chen H, Aksoy I, Gonnot F, Osteil P, Aubry M, Hamela C, et al. Reinforcement of STAT3 activity reprogrammes human embryonic stem cells to naive-like pluripotency. Nat Commun. 2015;6:7095 pubmed publisher
  • immunocytochemistry; human; 1:100
Pino Barrio M, García García E, Menéndez P, Martínez Serrano A. V-myc immortalizes human neural stem cells in the absence of pluripotency-associated traits. PLoS ONE. 2015;10:e0118499 pubmed publisher
  • immunocytochemistry; domestic rabbit; 1:50
Afanassieff M, Osteil P, Savatier P. Generation of Embryonic Stem Cells in Rabbits. Methods Mol Biol. 2016;1341:49-66 pubmed publisher
  • other; human
  • flow cytometry; human; 1:200
  • immunocytochemistry; human
Chou B, Gu H, Gao Y, Dowey S, Wang Y, Shi J, et al. A facile method to establish human induced pluripotent stem cells from adult blood cells under feeder-free and xeno-free culture conditions: a clinically compliant approach. Stem Cells Transl Med. 2015;4:320-32 pubmed publisher
  • immunocytochemistry; human
Cerbini T, Funahashi R, Luo Y, Liu C, Park K, Rao M, et al. Transcription activator-like effector nuclease (TALEN)-mediated CLYBL targeting enables enhanced transgene expression and one-step generation of dual reporter human induced pluripotent stem cell (iPSC) and neural stem cell (NSC) lines. PLoS ONE. 2015;10:e0116032 pubmed publisher
  • immunocytochemistry; human; 1:100; fig 3
Sanz Garcia A, Stojkovic M, Escobedo Lucea C. Growth of Human Pluripotent Stem Cells Using Functional Human Extracellular Matrix. Methods Mol Biol. 2016;1307:39-60 pubmed publisher
  • immunocytochemistry; mouse; 1:50
Afanassieff M, Tapponnier Y, Savatier P. Generation of Induced Pluripotent Stem Cells in Rabbits. Methods Mol Biol. 2016;1357:149-72 pubmed publisher
  • flow cytometry; human; 1:400
Turner J, Quek L, Titmarsh D, Krömer J, Kao L, Nielsen L, et al. Metabolic profiling and flux analysis of MEL-2 human embryonic stem cells during exponential growth at physiological and atmospheric oxygen concentrations. PLoS ONE. 2014;9:e112757 pubmed publisher
  • immunohistochemistry; human; 1:500; fig 1c
Johnson Kerner B, Ahmad F, Diaz A, Greene J, Gray S, Samulski R, et al. Intermediate filament protein accumulation in motor neurons derived from giant axonal neuropathy iPSCs rescued by restoration of gigaxonin. Hum Mol Genet. 2015;24:1420-31 pubmed publisher
  • flow cytometry; human; 1:300
Ovchinnikov D, Titmarsh D, Fortuna P, Hidalgo A, Alharbi S, Whitworth D, et al. Transgenic human ES and iPS reporter cell lines for identification and selection of pluripotent stem cells in vitro. Stem Cell Res. 2014;13:251-61 pubmed publisher
  • western blot; human; 1:500
Jha B, Rao M, Malik N. Motor neuron differentiation from pluripotent stem cells and other intermediate proliferative precursors that can be discriminated by lineage specific reporters. Stem Cell Rev. 2015;11:194-204 pubmed publisher
  • immunohistochemistry - paraffin section; pigs ; 1:100
  • flow cytometry; pigs ; 1:100
Park M, Park J, Kim M, Lee K, Park H, Yun J, et al. Development of a high-yield technique to isolate spermatogonial stem cells from porcine testes. J Assist Reprod Genet. 2014;31:983-91 pubmed publisher
  • western blot; pigs ; 1:200
Uh K, Park C, Choi K, Park J, Jeong Y, Roh S, et al. Analysis of imprinted IGF2/H19 gene methylation and expression in normal fertilized and parthenogenetic embryonic stem cells of pigs. Anim Reprod Sci. 2014;147:47-55 pubmed publisher
  • immunocytochemistry; dogs
Tobias I, Brooks C, Teichroeb J, Betts D. Derivation and culture of canine embryonic stem cells. Methods Mol Biol. 2013;1074:69-83 pubmed publisher
  • immunocytochemistry; pigs ; 1:50
Park K, Cha S, Ahn C, Woo H. Generation of porcine induced pluripotent stem cells and evaluation of their major histocompatibility complex protein expression in vitro. Vet Res Commun. 2013;37:293-301 pubmed publisher
  • flow cytometry; human
Stover A, Brick D, Nethercott H, Banuelos M, Sun L, O Dowd D, et al. Process-based expansion and neural differentiation of human pluripotent stem cells for transplantation and disease modeling. J Neurosci Res. 2013;91:1247-62 pubmed publisher
  • immunocytochemistry; human; 1:100
Sharma A, Diecke S, Zhang W, Lan F, He C, Mordwinkin N, et al. The role of SIRT6 protein in aging and reprogramming of human induced pluripotent stem cells. J Biol Chem. 2013;288:18439-47 pubmed publisher
  • immunocytochemistry; rhesus macaque; 1:200
Putkhao K, Kocerha J, Cho I, Yang J, Parnpai R, Chan A. Pathogenic cellular phenotypes are germline transmissible in a transgenic primate model of Huntington's disease. Stem Cells Dev. 2013;22:1198-205 pubmed publisher
  • immunocytochemistry; human
Yang S, Harnish E, Leeuw T, Dietz U, Batchelder E, Wright P, et al. Compound screening platform using human induced pluripotent stem cells to identify small molecules that promote chondrogenesis. Protein Cell. 2012;3:934-42 pubmed publisher
Gomez Giro G, Arias Fuenzalida J, Jarazo J, Zeuschner D, Ali M, Possemis N, et al. Synapse alterations precede neuronal damage and storage pathology in a human cerebral organoid model of CLN3-juvenile neuronal ceroid lipofuscinosis. Acta Neuropathol Commun. 2019;7:222 pubmed publisher
Yoshimatsu S, Sone T, Nakajima M, Sato T, Okochi R, Ishikawa M, et al. A versatile toolbox for knock-in gene targeting based on the Multisite Gateway technology. PLoS ONE. 2019;14:e0221164 pubmed publisher
Jiang Y, Liu F, Zou F, Zhang Y, Wang B, Zhang Y, et al. PBX homeobox 1 enhances hair follicle mesenchymal stem cell proliferation and reprogramming through activation of the AKT/glycogen synthase kinase signaling pathway and suppression of apoptosis. Stem Cell Res Ther. 2019;10:268 pubmed publisher
Kwart D, Gregg A, Scheckel C, Murphy E, Paquet D, Duffield M, et al. A Large Panel of Isogenic APP and PSEN1 Mutant Human iPSC Neurons Reveals Shared Endosomal Abnormalities Mediated by APP β-CTFs, Not Aβ. Neuron. 2019;104:256-270.e5 pubmed publisher
Annunziata I, van de Vlekkert D, Wolf E, Finkelstein D, Neale G, Machado E, et al. MYC competes with MiT/TFE in regulating lysosomal biogenesis and autophagy through an epigenetic rheostat. Nat Commun. 2019;10:3623 pubmed publisher
Tan H, Tan B, Goh W, Cua S, Choo A. In vivo surveillance and elimination of teratoma-forming human embryonic stem cells with monoclonal antibody 2448 targeting annexin A2. Biotechnol Bioeng. 2019;116:2996-3005 pubmed publisher
Liu L, Li Y, Guo N, Li S, Ma X, Zhang Y, et al. Therapeutic Potential of Patient iPSC-Derived iMelanocytes in Autologous Transplantation. Cell Rep. 2019;27:455-466.e5 pubmed publisher
Kono K, Sawada R, Kuroda T, Yasuda S, Matsuyama S, Matsuyama A, et al. Development of selective cytotoxic viral vectors for concentration of undifferentiated cells in cardiomyocytes derived from human induced pluripotent stem cells. Sci Rep. 2019;9:3630 pubmed publisher
Soda M, Saitoh I, Murakami T, Inada E, Iwase Y, Noguchi H, et al. Repeated human deciduous tooth-derived dental pulp cell reprogramming factor transfection yields multipotent intermediate cells with enhanced iPS cell formation capability. Sci Rep. 2019;9:1490 pubmed publisher
Carr Wilkinson J, Prathalingam N, Pal D, Moad M, Lee N, Sundaresh A, et al. Differentiation of Human Embryonic Stem Cells to Sympathetic Neurons: A Potential Model for Understanding Neuroblastoma Pathogenesis. Stem Cells Int. 2018;2018:4391641 pubmed publisher
Jeon H, Kim J, Choi J, Han E, Song C, Lee J, et al. Effects of the Extracts from Fruit and Stem of Camellia japonica on Induced Pluripotency and Wound Healing. J Clin Med. 2018;7: pubmed publisher
Whitworth D, Limnios I, Gauthier M, Weeratunga P, Ovchinnikov D, Baillie G, et al. Platypus Induced Pluripotent Stem Cells: the Unique Pluripotency Signature of a Monotreme. Stem Cells Dev. 2018;: pubmed publisher
Buskin A, Zhu L, Chichagova V, Basu B, Mozaffari Jovin S, Dolan D, et al. Disrupted alternative splicing for genes implicated in splicing and ciliogenesis causes PRPF31 retinitis pigmentosa. Nat Commun. 2018;9:4234 pubmed publisher
Ding D, Chu T, Liu H. Dedifferentiation of human uterine polyp stem cells into embryo-like cells during inducing pluripotency. Int J Biol Sci. 2018;14:1586-1598 pubmed publisher
Yang G, Hong H, Torres A, Malloy K, Choudhury G, Kim J, et al. Standards for Deriving Nonhuman Primate-Induced Pluripotent Stem Cells, Neural Stem Cells and Dopaminergic Lineage. Int J Mol Sci. 2018;19: pubmed publisher
Wang S, Liu Z, Ye Y, Li B, Liu T, Zhang W, et al. Ectopic hTERT expression facilitates reprograming of fibroblasts derived from patients with Werner syndrome as a WS cellular model. Cell Death Dis. 2018;9:923 pubmed publisher
Liu J, Higgins C, Whitehouse J, Harris S, Crawford H, Christiano A, et al. Hair Follicle Dermal Cells Support Expansion of Murine and Human Embryonic and Induced Pluripotent Stem Cells and Promote Haematopoiesis in Mouse Cultures. Stem Cells Int. 2018;2018:8631432 pubmed publisher
Karch C, Hernández D, Wang J, Marsh J, Hewitt A, Hsu S, et al. Human fibroblast and stem cell resource from the Dominantly Inherited Alzheimer Network. Alzheimers Res Ther. 2018;10:69 pubmed publisher
Gu H, Huang X, Xu J, Song L, Liu S, Zhang X, et al. Optimizing the method for generation of integration-free induced pluripotent stem cells from human peripheral blood. Stem Cell Res Ther. 2018;9:163 pubmed publisher
Ihry R, Worringer K, Salick M, Frias E, Ho D, Theriault K, et al. p53 inhibits CRISPR-Cas9 engineering in human pluripotent stem cells. Nat Med. 2018;24:939-946 pubmed publisher
Ali M, Khan S, Vasanth S, Ahmed M, Chen R, Na C, et al. Generation and Proteome Profiling of PBMC-Originated, iPSC-Derived Corneal Endothelial Cells. Invest Ophthalmol Vis Sci. 2018;59:2437-2444 pubmed publisher
Shafa M, Yang F, Fellner T, Rao M, Baghbaderani B. Human-Induced Pluripotent Stem Cells Manufactured Using a Current Good Manufacturing Practice-Compliant Process Differentiate Into Clinically Relevant Cells From Three Germ Layers. Front Med (Lausanne). 2018;5:69 pubmed publisher
Ferrer C, Alders M, Postma A, Park S, Klein M, Cetinbaş M, et al. An inactivating mutation in the histone deacetylase SIRT6 causes human perinatal lethality. Genes Dev. 2018;32:373-388 pubmed publisher
Saito S, Hiemori K, Kiyoi K, Tateno H. Glycome analysis of extracellular vesicles derived from human induced pluripotent stem cells using lectin microarray. Sci Rep. 2018;8:3997 pubmed publisher
Chai S, Wan X, Ramirez Navarro A, Tesar P, Kaufman E, Ficker E, et al. Physiological genomics identifies genetic modifiers of long QT syndrome type 2 severity. J Clin Invest. 2018;128:1043-1056 pubmed publisher
Wang Y, Zhao C, Hou Z, Yang Y, Bi Y, Wang H, et al. Unique molecular events during reprogramming of human somatic cells to induced pluripotent stem cells (iPSCs) at naïve state. elife. 2018;7: pubmed publisher
Melguizo Sanchís D, Xu Y, Taheem D, Yu M, Tilgner K, Bárta T, et al. iPSC modeling of severe aplastic anemia reveals impaired differentiation and telomere shortening in blood progenitors. Cell Death Dis. 2018;9:128 pubmed publisher
Parmar V, Parmar T, Arai E, Perusek L, Maeda A. A2E-associated cell death and inflammation in retinal pigmented epithelial cells from human induced pluripotent stem cells. Stem Cell Res. 2018;27:95-104 pubmed publisher
Cheng J, Park D, Berrios C, White E, Arora R, Yoon R, et al. Merkel cell polyomavirus recruits MYCL to the EP400 complex to promote oncogenesis. PLoS Pathog. 2017;13:e1006668 pubmed publisher
Shukla V, Rao M, ZHANG H, Beers J, Wangsa D, Wangsa D, et al. ASXL3 Is a Novel Pluripotency Factor in Human Respiratory Epithelial Cells and a Potential Therapeutic Target in Small Cell Lung Cancer. Cancer Res. 2017;77:6267-6281 pubmed publisher
Chen Z, Chang W, Etheridge A, Strickfaden H, Jin Z, Palidwor G, et al. Reprogramming progeria fibroblasts re-establishes a normal epigenetic landscape. Aging Cell. 2017;16:870-887 pubmed publisher
Crombie D, Curl C, Raaijmakers A, Sivakumaran P, Kulkarni T, Wong R, et al. Friedreich's ataxia induced pluripotent stem cell-derived cardiomyocytes display electrophysiological abnormalities and calcium handling deficiency. Aging (Albany NY). 2017;9:1440-1452 pubmed publisher
Teotia P, Sharma S, Airan B, Mohanty S. Feeder & basic fibroblast growth factor-free culture of human embryonic stem cells: Role of conditioned medium from immortalized human feeders. Indian J Med Res. 2016;144:838-851 pubmed publisher
Wong R, Lim S, Hung S, Jackson S, Khan S, Van Bergen N, et al. Mitochondrial replacement in an iPSC model of Leber's hereditary optic neuropathy. Aging (Albany NY). 2017;9:1341-1350 pubmed publisher
Shimojima M, Yuasa S, Motoda C, Yozu G, Nagai T, Ito S, et al. Emerin plays a crucial role in nuclear invagination and in the nuclear calcium transient. Sci Rep. 2017;7:44312 pubmed publisher
Woo C, Maier V, Davey R, Brennan J, Li G, Brothers J, et al. Gene activation of SMN by selective disruption of lncRNA-mediated recruitment of PRC2 for the treatment of spinal muscular atrophy. Proc Natl Acad Sci U S A. 2017;114:E1509-E1518 pubmed publisher
Cooper H, Yang Y, Ylikallio E, Khairullin R, Woldegebriel R, Lin K, et al. ATPase-deficient mitochondrial inner membrane protein ATAD3A disturbs mitochondrial dynamics in dominant hereditary spastic paraplegia. Hum Mol Genet. 2017;26:1432-1443 pubmed publisher
Neganova I, Chichagova V, Armstrong L, Lako M. A critical role for p38MAPK signalling pathway during reprogramming of human fibroblasts to iPSCs. Sci Rep. 2017;7:41693 pubmed publisher
Bharathan S, Manian K, Aalam S, Palani D, Deshpande P, Pratheesh M, et al. Systematic evaluation of markers used for the identification of human induced pluripotent stem cells. Biol Open. 2017;6:100-108 pubmed publisher
Zhu L, Gómez Durán A, Saretzki G, Jin S, Tilgner K, Melguizo Sanchís D, et al. The mitochondrial protein CHCHD2 primes the differentiation potential of human induced pluripotent stem cells to neuroectodermal lineages. J Cell Biol. 2016;215:187-202 pubmed
Millman J, Xie C, Van Dervort A, Gürtler M, Pagliuca F, Melton D. Generation of stem cell-derived ?-cells from patients with type 1 diabetes. Nat Commun. 2016;7:11463 pubmed publisher
Hung S, Van Bergen N, Jackson S, Liang H, Mackey D, Hernández D, et al. Study of mitochondrial respiratory defects on reprogramming to human induced pluripotent stem cells. Aging (Albany NY). 2016;8:945-57 pubmed publisher
Ito N, Hendriks W, Dhakal J, Vaine C, Liu C, Shin D, et al. Decreased N-TAF1 expression in X-linked dystonia-parkinsonism patient-specific neural stem cells. Dis Model Mech. 2016;9:451-62 pubmed publisher
Xing J, Toh Y, Xu S, Yu H. A method for human teratogen detection by geometrically confined cell differentiation and migration. Sci Rep. 2015;5:10038 pubmed publisher
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product information
Catalog Number :
MAB4360
Subcategory :
Stem Cell Research
Product Name :
Anti-TRA-1-60 Antibody, clone TRA-1-60
Product Type :
Antibodies
Clonality :
Monoclonal Antibody
Host Name :
Mouse
Antigen :
TRA-1-60
Clone :
clone TRA-1-60
Conjugate :
Purified
Isotype :
IgM
Product Description :
Anti-TRA-1-60 Antibody, clone TRA-1-60
Cross Reactivity :
Human
Background :
Human embryonal carcinoma (EC) cells are the stem cells of teratocarcinomas, and they are key components of germ cell tumors (GCTs). They express several high molecular weight glycoprotein antigens that are down-regulated upon differentiation. One of these antigens, defined by monoclonal antibody TRA-1-60, can be detected in the serum of GCT patients and provides a useful complement to the established serum markers human chorionic gonadotropin and α-fetoprotein, especially in those patients without elevated serum human chorionic gonadotropin or α-fetoprotein.
Immunogen :
Human embryonal carcinoma cell line 2102Ep
Specificity :
This antibody reacts with TRA-1-60 antigen that is expressed upon the surface of human tetracarcinoma stem cells (EC), human embryonic germ cells (EG) and human embryonic stem cells (ES). No immunoreactivity is seen with murine EC, EG or ES cells. Both the TRA-1-60 and TRA-1-81 monoclonal antibodies (MAB4381) recognize antigens that are associated with a pericellular matrix proteoglycan. TRA-1-60 reacts with a sialidase-sensitive epitope whilst TRA-1-81 reacts with an unknown epitope of the same molecule.
Package Size :
100 μg
Uses :
Western Blotting;Flow Cytometry;Immunofluorescence;Immunoprecipitation;Immunocytochemistry
Storage :
Stable for 1 year at from date of receipt.
company information
EMD Millipore
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Billerica, Massachusetts 01821
bioscienceshelp@emdchemical.com
https://www.emdmillipore.com
888-854-3417
headquarters: United States
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

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