TRA-2-49 Antibody, Liver/Bone/Kidney Alkaline Phosphatase, clone TRA-2-49/6E | EMD Millipore MAB4349 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

TRA-2-49 Antibody, Liver/Bone/Kidney Alkaline Phosphatase, clone TRA-2-49/6E

catalog :

MAB4349

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

TRA-2-49/6E

application :

immunocytochemistry, immunoprecipitation, flow cytometry

citations: 2

Reference
Yang J, Liao C, Pang C, Huang L, Lin Y, Chen Y, et al. Directed differentiation into neural lineages and therapeutic potential of porcine embryonic stem cells in rat Parkinson's disease model. Cell Reprogram. 2010;12:447-61 pubmed publisher
Yang J, Shiue Y, Liao C, Lin S, Chen L. Establishment and characterization of novel porcine embryonic stem cell lines expressing hrGFP. Cloning Stem Cells. 2009;11:235-44 pubmed publisher

product information

Catalog Number :

MAB4349

Subcategory :

Stem Cell Research

Product Name :

Anti-TRA-2-49 Antibody, Liver/Bone/Kidney Alkaline Phosphatase, clone TRA-2-49/6E

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Host Name :

Mouse

Antigen :

TRA-2-49

Clone :

clone TRA-2-49/6E

Conjugate :

Purified

Isotype :

IgG1

Product Description :

Anti-TRA-2-49 Antibody, Liver/Bone/Kidney Alkaline Phosphatase, clone TRA-2-49/6E

Cross Reactivity :

Human;Pig;Rabbit;Feline

Background :

In humans, four isoforms of alkaline phosphatase exist: intestinal, placental, placenta-like (germ cell type) and tissue-nonspecific. The tissue-nonspecific isoform of alkaline phosphatase is present in bone, liver and kidney; it differs from the other forms by posttranslational modification. Undifferentiated human Embryonal Carcinoma (EC) and Embryonic Stem (ES) cells have been shown to express very high levels of Alkaline Phosphatase isozyme that is indistinguishable from the isozyme found in liver, bone and kidney. Expression levels of AP decrease following stem cell differentiation. This clone can be used to monitor the expression of the Human Liver / Bone / Kidney isozyme of Alkaline Phosphatase (AP), and hence the differentiation status of human EC and ES cells by flow cytometry.

Immunogen :

2102Ep human Embryonal Carcinoma Cells

Specificity :

Undifferentiated human Embryonal Carcinoma (EC) and Embryonic Stem (ES) cells have been shown to express very high levels of Alkaline Phosphatase isozyme that is indistinguishable from the isozyme found in liver, bone and kidney. Expression levels of AP decrease following stem cell differentiation. This clone can be used in flow cytometry to determine the expression of the Liver / Bone / Kidney isozyme of Alkaline Phosphatase (AP), and hence monitor the differentiation status of EC and ES cells.

Package Size :

100 μg

Uses :

Flow Cytometry;Immunofluorescence;Immunocytochemistry;Immunoprecipitation

Storage :

Stable for 1 year at from date of receipt.