This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
EMD Millipore
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
product type :
antibody
product name :
Dihydropyridine-sensitive Calcium Channel α 1 Subunit Antibody, clone 1a
catalog :
MAB427
quantity :
100 µL
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
mAB 1a
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section
citations: 10
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; loading ...; fig 4a
Lo H, Nixon S, Hall T, Cowling B, Ferguson C, Morgan G, et al. The caveolin-cavin system plays a conserved and critical role in mechanoprotection of skeletal muscle. J Cell Biol. 2015;210:833-49 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:500
  • western blot; mouse
Tummala S, Neinstein A, Fina M, Dhingra A, Vardi N. Localization of Cacna1s to ON bipolar dendritic tips requires mGluR6-related cascade elements. Invest Ophthalmol Vis Sci. 2014;55:1483-92 pubmed publisher
  • immunohistochemistry - frozen section; mouse; fig 3
Rederstorff M, Castets P, Arbogast S, Laine J, Vassilopoulos S, Beuvin M, et al. Increased muscle stress-sensitivity induced by selenoprotein N inactivation in mouse: a mammalian model for SEPN1-related myopathy. PLoS ONE. 2011;6:e23094 pubmed publisher
Tajika Y, Takahashi M, Khairani A, Ueno H, Murakami T, Yorifuji H. Vesicular transport system in myotubes: ultrastructural study and signposting with vesicle-associated membrane proteins. Histochem Cell Biol. 2014;141:441-54 pubmed publisher
Couchoux H, Bichraoui H, Chouabe C, Altafaj X, Bonvallet R, Allard B, et al. Caveolin-3 is a direct molecular partner of the Cav1.1 subunit of the skeletal muscle L-type calcium channel. Int J Biochem Cell Biol. 2011;43:713-20 pubmed publisher
Mateizel I, Spits C, De Rycke M, Liebaers I, Sermon K. Derivation, culture, and characterization of VUB hESC lines. In Vitro Cell Dev Biol Anim. 2010;46:300-8 pubmed publisher
Couchoux H, Allard B, Legrand C, Jacquemond V, Berthier C. Loss of caveolin-3 induced by the dystrophy-associated P104L mutation impairs L-type calcium channel function in mouse skeletal muscle cells. J Physiol. 2007;580:745-54 pubmed
Esposito A, Germinario E, Zanin M, Palade P, Betto R, Danieli Betto D. Isoform switching in myofibrillar and excitation-contraction coupling proteins contributes to diminished contractile function in regenerating rat soleus muscle. J Appl Physiol (1985). 2007;102:1640-8 pubmed
Szikra T, Krizaj D. The dynamic range and domain-specific signals of intracellular calcium in photoreceptors. Neuroscience. 2006;141:143-55 pubmed
Bidaud I, Monteil A, Nargeot J, Lory P. Properties and role of voltage-dependent calcium channels during mouse skeletal muscle differentiation. J Muscle Res Cell Motil. 2006;27:75-81 pubmed
product information
Catalog Number :
MAB427
Subcategory :
Neuroscience
Product Name :
Anti-Dihydropyridine-sensitive Calcium Channel α 1 Subunit Antibody, clone 1a
Product Type :
Antibodies
Clonality :
Monoclonal Antibody
Gene ID :
Q13698
Host Name :
Mouse
Antigen :
Dihydropyridine-sensitive Calcium Channel α 1 Subunit
Clone :
mAB 1a
Conjugate :
Ascites
Isotype :
IgG1
Product Description :
Anti-Dihydropyridine-sensitive Calcium Channel α 1 Subunit Antibody, clone 1a
Cross Reactivity :
Human;Mouse;Rat;Rabbit
Specificity :
Dihydropyridine calcium channel, a1 subunit as determined by Western blot (~210 kDa), immunoprecipitation and functional test. Membrane preparations are recommended. The mouse muscle cell line, BC3H1 functions as a good positive control cell line. Reactive with L-type calcium channel alpha1 subunit. Specific for small cell carcinoma and neuroblastoma by FACS analysis. No interaction with squamous cell carcinoma or with cardiac calcium chanel isoforms.
Package Size :
100 µL
Uses :
Flow Cytometry;Immunoprecipitation;Western Blotting
Storage :
Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
company information
EMD Millipore
290 Concord Road
Billerica, Massachusetts 01821
bioscienceshelp@emdchemical.com
https://www.emdmillipore.com
888-854-3417
headquarters: United States
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

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