This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
EMD Millipore
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
product type :
antibody
product name :
MDR1 Antibody, extracellular human specific Pgp, clone MC57
catalog :
MAB4163
quantity :
100 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
MC57
reactivity :
human
application :
western blot, immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section
citations: 2
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; fig 1
Lee T, Liu C, Chang Y, Nieh S, Lin Y, Jao S, et al. Increased chemoresistance via Snail-Raf kinase inhibitor protein signaling in colorectal cancer in response to a nicotine derivative. Oncotarget. 2016;7:23512-20 pubmed publisher
Konduri S, Ticku J, Bobustuc G, Sutphin R, Colon J, Isley B, et al. Blockade of MGMT expression by O6 benzyl guanine leads to inhibition of pancreatic cancer growth and induction of apoptosis. Clin Cancer Res. 2009;15:6087-95 pubmed publisher
product information
Catalog Number :
MAB4163
Subcategory :
Metabolism
Product Name :
Anti-MDR1 Antibody, extracellular human specific Pgp, clone MC57
Product Type :
Antibodies
Clonality :
Monoclonal Antibody
Gene ID :
P08183
Host Name :
Mouse
Antigen :
MDR1
Clone :
MC57
Conjugate :
Purified
Isotype :
IgG2aκ
Product Description :
Anti-MDR1 Antibody, extracellular human specific Pgp, clone MC57
Cross Reactivity :
Human
ALT Names :
P-glycoprotein; CD243; p170; Pgp
Immunogen :
Living intact human multidrug-resistant cells
Specificity :
MDR-1 clone MC57 recgonizes the inactivated form of Pgp and recognizes the conformational epitope in Immunohistochemistry on paraffin sections.
Package Size :
100 µg
Uses :
Flow Cytometry;Immunohistochemistry;Immunohistochemistry (Paraffin)
Storage :
Maintain at 2-8°C in undiluted aliquots for up to 6 months.
company information
EMD Millipore
290 Concord Road
Billerica, Massachusetts 01821
bioscienceshelp@emdchemical.com
https://www.emdmillipore.com
888-854-3417
headquarters: United States
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

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