MDR1 Antibody, extracellular human specific Pgp, clone MM4.17 | EMD Millipore MAB4162 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

MDR1 Antibody, extracellular human specific Pgp, clone MM4.17

catalog :

MAB4162

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

MM4.17

reactivity :

human

application :

immunohistochemistry, flow cytometry

citations: 3

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human	Yasunaga M, Matsumura Y. Role of SLC6A6 in promoting the survival and multidrug resistance of colorectal cancer. Sci Rep. 2014;4:4852 pubmed publisher
	Chartrain M, Riond J, Stennevin A, Vandenberghe I, Gomes B, Lamant L, et al. Melanoma chemotherapy leads to the selection of ABCB5-expressing cells. PLoS ONE. 2012;7:e36762 pubmed publisher
	Zhang J, Zhou F, Wu X, Zhang X, Chen Y, ZHA B, et al. Cellular pharmacokinetic mechanisms of adriamycin resistance and its modulation by 20(S)-ginsenoside Rh2 in MCF-7/Adr cells. Br J Pharmacol. 2012;165:120-34 pubmed publisher

product information

Catalog Number :

MAB4162

Subcategory :

Metabolism

Product Name :

Anti-MDR1 Antibody, extracellular human specific Pgp, clone MM4.17

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P08183

Host Name :

Mouse

Antigen :

MDR1

Clone :

MM4.17

Conjugate :

Purified

Isotype :

IgG2aκ

Product Description :

Anti-MDR1 Antibody, extracellular human specific Pgp, clone MM4.17

Cross Reactivity :

Human

ALT Names :

P-glycoprotein; CD243; p170; Pgp

Immunogen :

Living intact human multidrug-resistant cells

Specificity :

Recognizes a mapped epitope in the extracellular Pgp domain and detects low-level Pgp expression in living (intact) human MDR cells (Cianfriglia, 2002). The epitope has been mapped to the single amino acid level using different techniques (Cianfriglia, 1994 and Poloni, 1995).

Package Size :

100 μg

Uses :

Flow Cytometry;Immunohistochemistry

Storage :

Maintain for 1 year at 2–8°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.