MRP2 Antibody, clone M2 I-4 | EMD Millipore MAB4148 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

MRP2 Antibody, clone M2 I-4

catalog :

MAB4148

quantity :

100 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

M2 I-4

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry

citations: 4

Published Application/Species/Sample/Dilution	Reference
western blot; human	Huuskonen P, Myllynen P, Storvik M, Pasanen M. The effects of aflatoxin B1 on transporters and steroid metabolizing enzymes in JEG-3 cells. Toxicol Lett. 2013;218:200-6 pubmed publisher
	Kummu M, Sieppi E, Wallin K, Rautio A, Vahakangas K, Myllynen P. Cadmium inhibits ABCG2 transporter function in BeWo choriocarcinoma cells and MCF-7 cells overexpressing ABCG2. Placenta. 2012;33:859-65 pubmed publisher
	Li C, Schuetz J, Naren A. Tobacco carcinogen NNK transporter MRP2 regulates CFTR function in lung epithelia: implications for lung cancer. Cancer Lett. 2010;292:246-53 pubmed publisher
	Myllynen P, Kummu M, Kangas T, Ilves M, Immonen E, Rysa J, et al. ABCG2/BCRP decreases the transfer of a food-born chemical carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in perfused term human placenta. Toxicol Appl Pharmacol. 2008;232:210-7 pubmed publisher

product information

Catalog Number :

MAB4148

Subcategory :

Metabolism

Product Name :

Anti-MRP2 Antibody, clone M2 I-4

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

Q92887

Host Name :

Mouse

Antigen :

MRP2

Clone :

M2 I-4

Conjugate :

Culture Supernatant

Isotype :

IgG1

Product Description :

Anti-MRP2 Antibody, clone M2 I-4

Cross Reactivity :

Human

ALT Names :

cMOAT

Immunogen :

Fusion protein of MRP2 containing aa 215-310 of the protein.

Specificity :

This antibody reacts with an internal epitope of MRP2, a 190-200 kDa transmembrane protein previously known as the canalicular multi-organic anion transporter (cMOAT). MRP2 is a member of the MRP family of multidrug resistance related proteins, and MRP2 overexpression has been observed in a subset of cisplatin resistant cell lines. This antibody does not cross-react with the human MDR1, MRP1, MRP3 or MRP5 gene products.

Package Size :

100 µg

Uses :

Western Blotting;Immunocytochemistry;Immunohistochemistry

Storage :

Maintain refrigerated at 2-8°C for up to 6 months. For long-term storage store at -20°C.