p16 Antibody, clone D25 | EMD Millipore MAB4133 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

p16 Antibody, clone D25

catalog :

MAB4133

quantity :

100 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

D25

reactivity :

human

application :

western blot, immunohistochemistry

citations: 8

Published Application/Species/Sample/Dilution	Reference
western blot; human	Karoopongse E, Yeung C, Byon J, Ramakrishnan A, Holman Z, Jiang P, et al. The KDM2B- let-7b -EZH2 axis in myelodysplastic syndromes as a target for combined epigenetic therapy. PLoS ONE. 2014;9:e107817 pubmed publisher
	Fu H, Chuang I, Yang Y, Chuang P, Lin H, Ou Y, et al. Low P16INK4A Expression Associated with High Expression of Cancer Stem Cell Markers Predicts Poor Prognosis in Cervical Cancer after Radiotherapy. Int J Mol Sci. 2018;19: pubmed publisher
	Almangush A, Heikkinen I, Makitie A, Coletta R, Läärä E, Leivo I, et al. Prognostic biomarkers for oral tongue squamous cell carcinoma: a systematic review and meta-analysis. Br J Cancer. 2017;117:856-866 pubmed publisher
	Tursiella M, Bowman E, Wanzeck K, Throm R, Liao J, Zhu J, et al. Epstein-Barr virus nuclear antigen 3A promotes cellular proliferation by repression of the cyclin-dependent kinase inhibitor p21WAF1/CIP1. PLoS Pathog. 2014;10:e1004415 pubmed publisher
	Grønhøj Larsen C, Gyldenløve M, Jensen D, Therkildsen M, Kiss K, Norrild B, et al. Correlation between human papillomavirus and p16 overexpression in oropharyngeal tumours: a systematic review. Br J Cancer. 2014;110:1587-94 pubmed publisher
	Zhao N, Ang M, Yin X, Patel M, Fritchie K, Thorne L, et al. Different cellular p16(INK4a) localisation may signal different survival outcomes in head and neck cancer. Br J Cancer. 2012;107:482-90 pubmed publisher
	Ang M, Patel M, Yin X, Sundaram S, Fritchie K, Zhao N, et al. High XRCC1 protein expression is associated with poorer survival in patients with head and neck squamous cell carcinoma. Clin Cancer Res. 2011;17:6542-52 pubmed publisher
	Andrews E, Shores C, Hayes D, Couch M, Southerland J, Morris D, et al. Concurrent human papillomavirus-associated tonsillar carcinoma in 2 couples. J Infect Dis. 2009;200:882-7 pubmed publisher

product information

Catalog Number :

MAB4133

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-p16 Antibody, clone D25

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

Q8N726

Host Name :

Mouse

Antigen :

p16

Clone :

D25

Conjugate :

Purified

Isotype :

IgG1

Product Description :

Anti-p16 Antibody, clone D25

Cross Reactivity :

Human

ALT Names :

INK4a; MTS1; CDK4IN; CDKN2

Immunogen :

Recombinant p16 fusion protein from E. coli.

Specificity :

P16* is a major tumor suppressor gene, which is known to be deleted or mutated in many types of human cancers. Antibody MAB4133 binds specifically to p16 in its recombinant or native form. It also recognizes p16 expressed by melanomas and neve in situ.

Package Size :

100 µg

Uses :

Western Blotting;Immunohistochemistry

Storage :

Maintain refrigerated at 2-8°C in undiluted aliquots for up to 12 months.