Multi-Drug Resistance Related Protein Antibody, clone MRPm6 | EMD Millipore MAB4122 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Multi-Drug Resistance Related Protein Antibody, clone MRPm6

catalog :

MAB4122

quantity :

100 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

MRPm6

The same clone is also sold as:

OriGene: AM32054SU-N
Enzo Life Sciences: ALX-801-013-C250, ALX-801-013-C500

reactivity :

human

application :

western blot, immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section

citations: 3

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; human	Kovalev A, Tsvetaeva D, Grudinskaja T. Role of ABC-cassette transporters (MDR1, MRP1, BCRP) in the development of primary and acquired multiple drug resistance in patients with early and metastatic breast cancer. Exp Oncol. 2013;35:287-90 pubmed
	Zhang D, Nunoya K, Vasa M, Gu H, Cole S, Deeley R. Mutational analysis of polar amino acid residues within predicted transmembrane helices 10 and 16 of multidrug resistance protein 1 (ABCC1): effect on substrate specificity. Drug Metab Dispos. 2006;34:539-46 pubmed
	Di Nicolantonio F, Mercer S, Knight L, Gabriel F, Whitehouse P, Sharma S, et al. Cancer cell adaptation to chemotherapy. BMC Cancer. 2005;5:78 pubmed

product information

Catalog Number :

MAB4122

Subcategory :

Metabolism

Product Name :

Anti-Multi-Drug Resistance Related Protein Antibody, clone MRPm6

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P33527

Host Name :

Mouse

Antigen :

Multi-Drug Resistance Related Protein

Clone :

MRPm6

Conjugate :

Culture Supernatant

Isotype :

IgG1

Product Description :

Anti-Multi-Drug Resistance Related Protein Antibody, clone MRPm6

Cross Reactivity :

Human

ALT Names :

MRP

Specificity :

MRPm6 reacts with an internal epitope of MRP, a 180-195 kDa transmembrane transporter protein overexpressed in various human non-P-glycoprotein MDR tumor cell lines. MRPm6 was raised against a bacterial fusion protein of MRP, containing a segment of 170 amino acids in the carboxy terminal end and part of the carboxy proximal nucleotide binding domain of the protein. MRPm6 does not cross-react with the human MDR1 and MDR3 gene products (Flens et al., 1994).

Package Size :

100 µg

Uses :

Flow Cytometry;Western Blotting;Immunohistochemistry (Paraffin)

Storage :

Store at -20°C in undiluted aliquots. May be stored at 2-8°C for short term use. Avoid repeated freeze-thaw cycles.