MRP1, clone QCRL-3 | EMD Millipore MAB4110 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

MRP1, clone QCRL-3

catalog :

MAB4110

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

QCRL-3

The same clone is also sold as:

BioLegend: 370302, 370303, 370306, 370305, 370304, 370308
Santa Cruz Biotechnology: sc-18873
Abnova: MAB5157

reactivity :

human

application :

immunocytochemistry, immunoprecipitation, flow cytometry

product information

Catalog Number :

MAB4110

Category :

Antibodies

Subcategory :

Metabolism

Product Name :

Anti-MRP1, clone QCRL-3

Product Type :

Antibodies

Clonality :

Monoclonal

Gene ID :

NM_019901.1, NM_019902.1, NM_004996.3, NM_019862.2, NM_019898.2, NM_019899.2, NM_019900.2

Host Name :

Clone :

QCRL-3

Conjugate :

Purified

Isotype :

IgG2a

Product Description :

Anti-MRP1, clone QCRL-3

Cross Reactivity :

Human

Immunogen :

Non-denatured membranes prepared from the human small cell lung cancer cell line, H69AR, which highly overexpresses MRP1 (Cole, 1992; Hipfner, 1994).

Specificity :

Reacts with a conformation-dependent internal epitope of MRP1, a 190 kDa transmembrane phosphoglycoprotein overexpressed in various human multidrug resistant tumor cell lines and tumors (Cole, 1992; Hipfner, 1994; Hipfner, 1999a) . QCRL-3 inhibits ATP-dependent MRP1 transport activity in inside-out membrane vesicles, and its epitope has been localized to the first nucleotide binding domain of MRP1 between amino acids 617 and 932 (Hipfner, 1999b). Does not cross react with the human MDR1 or MDR3 gene products.

Package Size :

100 ug

Uses :

FC, IP, IC, FUNC

Storage :

Store at 2-8°C for up to 3 months. For longer term storage, aliquot and freeze at -20°C.