MRP1 Antibody, clone QCRL-1 | EMD Millipore MAB4100 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

MRP1 Antibody, clone QCRL-1

catalog :

MAB4100

quantity :

100 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

QCRL-1

The same clone is also sold as:

BioLegend: 370104, 370102, 370106, 370103
MilliporeSigma: M9067
Santa Cruz Biotechnology: sc-18835

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, other

citations: 7

Published Application/Species/Sample/Dilution	Reference
other; human; 1:50; fig 3b	Midde N, Sinha N, Lukka P, Meibohm B, Kumar S. Alterations in cellular pharmacokinetics and pharmacodynamics of elvitegravir in response to ethanol exposure in HIV-1 infected monocytic (U1) cells. PLoS ONE. 2017;12:e0172628 pubmed publisher
immunocytochemistry; human; 1:25; fig 2h	Clark P, Al Ahmad A, Qian T, Zhang R, Wilson H, Weichert J, et al. Analysis of Cancer-Targeting Alkylphosphocholine Analogue Permeability Characteristics Using a Human Induced Pluripotent Stem Cell Blood-Brain Barrier Model. Mol Pharm. 2016;13:3341-9 pubmed publisher
immunocytochemistry; human; 1:25; fig 2	Stebbins M, Wilson H, Canfield S, Qian T, Palecek S, Shusta E. Differentiation and characterization of human pluripotent stem cell-derived brain microvascular endothelial cells. Methods. 2016;101:93-102 pubmed publisher
flow cytometry; human immunocytochemistry; human	Loganzo F, Tan X, Sung M, Jin G, Myers J, Melamud E, et al. Tumor cells chronically treated with a trastuzumab-maytansinoid antibody-drug conjugate develop varied resistance mechanisms but respond to alternate treatments. Mol Cancer Ther. 2015;14:952-63 pubmed publisher
	Ohshima M, Kamei S, Fushimi H, Mima S, Yamada T, Yamamoto T. Prediction of Drug Permeability Using In Vitro Blood-Brain Barrier Models with Human Induced Pluripotent Stem Cell-Derived Brain Microvascular Endothelial Cells. Biores Open Access. 2019;8:200-209 pubmed publisher
	Fromme J, Kim J. A rapid and quantitative coat protein complex II vesicle formation assay using luciferase reporters. Anal Biochem. 2012;421:482-8 pubmed publisher
	Hamatake M, Aoki T, Futahashi Y, Urano E, Yamamoto N, Komano J. Ligand-independent higher-order multimerization of CXCR4, a G-protein-coupled chemokine receptor involved in targeted metastasis. Cancer Sci. 2009;100:95-102 pubmed publisher

product information

Catalog Number :

MAB4100

Subcategory :

Metabolism

Product Name :

Anti-MRP1 Antibody, clone QCRL-1

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P33527

Host Name :

Mouse

Antigen :

MRP1

Clone :

QCRL-1

Conjugate :

Purified

Isotype :

IgG1

Product Description :

Anti-MRP1 Antibody, clone QCRL-1

Cross Reactivity :

Human

ALT Names :

Multidrug Resistance Protein-1

Immunogen :

Non-denatured membranes prepared from the human small cell lung cancer cell line, H69AR, which highly overexpresses MRP1 (Cole et al., 1992; Hipfner et al., 1994, 1999).

Specificity :

Reacts with a defined linear epitope (aa 918-924) of MRP1, a 190 kDa transmembrane phosphoglycoprotein overexpressed in various human multidrug resistant tumor cell lines and tumors (Cole et al., 1992; Hipfner et al., 1994, 1996, 1999; Wright et al, 1998). Does not cross react with the mouse mrp1, or human MDR1, MDR3, MRP2, MRP3, MRP4, MRP5 or MRP6 gene products.

Package Size :

100 µg

Uses :

Flow Cytometry;Western Blotting;Immunocytochemistry;Immunohistochemistry;Immunohistochemistry (Paraffin)

Storage :

Store at 2-8 C for up to 3 months. For longer term storage, aliquot and freeze at -20 C.