PPAR γ Antibody, isoform 1&2 | EMD Millipore MAB3872 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

PPAR γ Antibody, isoform 1&2

catalog :

MAB3872

quantity :

100 μL

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1H4

reactivity :

African green monkey, human, mouse

application :

western blot, ELISA, immunocytochemistry, immunoprecipitation, immunohistochemistry - frozen section

citations: 8

Published Application/Species/Sample/Dilution	Reference
immunoprecipitation; mouse western blot; mouse	Han Y, Choi Y, Lee S, Jin Y, Cheong H, Lee K. Yin Yang 1 is a multi-functional regulator of adipocyte differentiation in 3T3-L1 cells. Mol Cell Endocrinol. 2015;413:217-27 pubmed publisher
immunohistochemistry - frozen section; African green monkey; 1:500	Swanson C, Emborg M. Expression of peroxisome proliferator-activated receptor-gamma in the substantia nigra of hemiparkinsonian nonhuman primates. Neurol Res. 2014;36:634-46 pubmed publisher
western blot; human	Kazantseva J, Kivil A, Tints K, Kazantseva A, Neuman T, Palm K. Alternative splicing targeting the hTAF4-TAFH domain of TAF4 represses proliferation and accelerates chondrogenic differentiation of human mesenchymal stem cells. PLoS ONE. 2013;8:e74799 pubmed publisher
western blot; human	Schipper B, Marra K, Zhang W, Donnenberg A, Rubin J. Regional anatomic and age effects on cell function of human adipose-derived stem cells. Ann Plast Surg. 2008;60:538-44 pubmed publisher
western blot; mouse; 1:1000	Mathews W, Foss C, Stoermer D, Ravert H, Dannals R, Henke B, et al. Synthesis and biodistribution of (11)C-GW7845, a positron-emitting agonist for peroxisome proliferator-activated receptor-{gamma}. J Nucl Med. 2005;46:1719-26 pubmed
	Lu H, Gao Z, Zhao Z, Weng J, Ye J. Transient hypoxia reprograms differentiating adipocytes for enhanced insulin sensitivity and triglyceride accumulation. Int J Obes (Lond). 2016;40:121-8 pubmed publisher
	Abbott B, Wood C, Watkins A, Tatum Gibbs K, Das K, Lau C. Effects of perfluorooctanoic acid (PFOA) on expression of peroxisome proliferator-activated receptors (PPAR) and nuclear receptor-regulated genes in fetal and postnatal CD-1 mouse tissues. Reprod Toxicol. 2012;33:491-505 pubmed publisher
	Cawthorn W, Bree A, Yao Y, Du B, Hemati N, Martinez Santibañez G, et al. Wnt6, Wnt10a and Wnt10b inhibit adipogenesis and stimulate osteoblastogenesis through a ?-catenin-dependent mechanism. Bone. 2012;50:477-89 pubmed publisher

product information

Catalog Number :

MAB3872

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-PPAR γ Antibody, isoform 1&2

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P37231;P37231

Host Name :

Mouse

Antigen :

PPAR γ

Clone :

1H4

Conjugate :

Ascites

Isotype :

IgG1

Product Description :

Anti-PPAR γ Antibody, isoform 1&2

Cross Reactivity :

Human;Mouse

Background :

Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors involved in lipid transport and metabolism. As such, their roles in chronic diseases such as diabetes, obesity, atherosclerosis and cancer are heavily investigated. Transcriptional activity of PPARs is regulated by fatty acid binding. Three PPAR isotypes have been identified: a, b and g. PPARg stimulates lipolysis of circulating triglycerides and the subsequent uptake of fatty acids into adipose cells. PPARs can bind to DNA only as a heterodimer with the retinoid X receptor (RXR).

ALT Names :

PPAR gamma

Immunogen :

Synthetic peptide from amino acids 107-121 of human PPAR gamma2.

Specificity :

Reacts with human PPAR gamma2. The antibody also reacts with PPAR gamma1 due to immunogen sequence homology. The immunogen shows no homology with PPAR alpha or PPAR beta.

Package Size :

100 μL

Uses :

ELISA;Immunocytochemistry;Western Blotting

Storage :

Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.