β-Catenin Antibody, clone 9F12.2 | EMD Millipore MAB3790 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

β-Catenin Antibody, clone 9F12.2

catalog :

MAB3790

quantity :

200 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

9F12.2

reactivity :

human

application :

western blot

citations: 1

Reference
Martins P, Haas M, Obici S. Central nervous system delivery of the antipsychotic olanzapine induces hepatic insulin resistance. Diabetes. 2010;59:2418-25 pubmed publisher

product information

Catalog Number :

MAB3790

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-β-Catenin Antibody, clone 9F12.2

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P35222

Host Name :

Mouse

Antigen :

β-Catenin

Clone :

9F12.2

Conjugate :

Purified

Isotype :

IgG1κ

Product Description :

Anti-β-Catenin Antibody, clone 9F12.2

Cross Reactivity :

Human

Background :

Beta-catenin, the vertebrate homologue of Drosophila segment polarity gene armadillo, and key element of the Wnt signal transduction pathways, is important in embryogenesis, cell transformation, and intercellular adhesion including the adhesion, motility and metastasis of cancer cells. Thus, catenin protein expression, regulation and localization are potentially important markers to predict motility and invasiveness of epithelial neoplasms. Besides adhesion functions, beta-catenin binds to the tumor suppressor gene APC. APC mutation disturbs the equilibrium and cytoplasmic levels of free beta-catenin level in the cell and may have a role in tumorigenesis.

Immunogen :

Synthetic peptide corresponding to residues 27-37 of Human beta catenin. Sequence is 100% identical in mouse, rat, Xenopus, zebrafish, chicken, porcine, and gerbil.

Specificity :

Recognizes human beta catenin. This antibody detects a band of approximately 97 kDa in Western blot analysis of A431 cell lysate.

Package Size :

200 µg

Uses :

Western Blotting

Storage :

Maintain at 2-8°C for up to 12 months from date of receipt.