This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
EMD Millipore
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
product type :
antibody
product name :
MAP2A Antibody, 2B
catalog :
MAB378
quantity :
100 µL
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
AP20

The same clone is also sold as:
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - free floating section
citations: 144
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; rat; 1:100; fig 1a
  • immunocytochemistry; human; 1:100; loading ...; fig 1a
Welty S, Teng Y, Liang Z, Zhao W, Sanders L, Greenamyre J, et al. RAD52 is required for RNA-templated recombination repair in post-mitotic neurons. J Biol Chem. 2018;293:1353-1362 pubmed publisher
  • immunohistochemistry; mouse; 1:1000; loading ...; fig 1a
Pchitskaya E, Kraskovskaya N, Chernyuk D, Popugaeva E, Zhang H, Vlasova O, et al. Stim2-Eb3 Association and Morphology of Dendritic Spines in Hippocampal Neurons. Sci Rep. 2017;7:17625 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:500; loading ...; fig 3
Rotoli D, Pérez Rodríguez N, Morales M, Maeso M, Avila J, Mobasheri A, et al. IQGAP1 in Podosomes/Invadosomes Is Involved in the Progression of Glioblastoma Multiforme Depending on the Tumor Status. Int J Mol Sci. 2017;18: pubmed publisher
  • immunocytochemistry; human; 1:250; fig 3a,3b
Sun Y, Paşca S, Portmann T, Goold C, Worringer K, Guan W, et al. A deleterious Nav1.1 mutation selectively impairs telencephalic inhibitory neurons derived from Dravet Syndrome patients. elife. 2016;5: pubmed publisher
  • immunocytochemistry; mouse; fig 4a
Ryu J, Hong B, Kim Y, Yang E, Choi M, Kim H, et al. Neuregulin-1 attenuates cognitive function impairments in a transgenic mouse model of Alzheimer's disease. Cell Death Dis. 2016;7:e2117 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:1000; fig 1
Popugaeva E, Pchitskaya E, Speshilova A, Alexandrov S, Zhang H, Vlasova O, et al. STIM2 protects hippocampal mushroom spines from amyloid synaptotoxicity. Mol Neurodegener. 2015;10:37 pubmed publisher
  • immunohistochemistry - free floating section; mouse
  • immunoprecipitation; mouse
  • immunocytochemistry; mouse
  • immunoprecipitation; rat
  • immunocytochemistry; rat
Fields J, Dumaop W, Eleuteri S, Elueteri S, Campos S, Serger E, et al. HIV-1 Tat alters neuronal autophagy by modulating autophagosome fusion to the lysosome: implications for HIV-associated neurocognitive disorders. J Neurosci. 2015;35:1921-38 pubmed publisher
  • immunocytochemistry; mouse; 1:150
Hung Y, Chang S, Huang C, Yin J, Hwang C, Yang L, et al. Inhibitor of Differentiation-1 and Hypoxia-Inducible Factor-1 Mediate Sonic Hedgehog Induction by Amyloid Beta-Peptide in Rat Cortical Neurons. Mol Neurobiol. 2016;53:793-809 pubmed publisher
  • immunocytochemistry; human
  • western blot; human
Carlessi L, Fusar Poli E, Bechi G, Mantegazza M, Pascucci B, Narciso L, et al. Functional and molecular defects of hiPSC-derived neurons from patients with ATM deficiency. Cell Death Dis. 2014;5:e1342 pubmed publisher
  • immunocytochemistry; rat; 1:200
Ramamoorthy P, Shi H. Ischemia induces different levels of hypoxia inducible factor-1? protein expression in interneurons and pyramidal neurons. Acta Neuropathol Commun. 2014;2:51 pubmed publisher
  • immunocytochemistry; mouse
Lysko D, Putt M, Golden J. SDF1 reduces interneuron leading process branching through dual regulation of actin and microtubules. J Neurosci. 2014;34:4941-62 pubmed publisher
  • immunohistochemistry - free floating section; rat; 1:2000; fig 12.33.4.
Tapias V, Greenamyre J. A rapid and sensitive automated image-based approach for in vitro and in vivo characterization of cell morphology and quantification of cell number and neurite architecture. Curr Protoc Cytom. 2014;68:12.33.1-22 pubmed publisher
  • immunocytochemistry; mouse
Lin C, Lee D, Chang H, Chiu I, Hsu C. Single-cell enzyme-free dissociation of neurospheres using a microfluidic chip. Anal Chem. 2013;85:11920-8 pubmed publisher
  • flow cytometry; human; 1:500
  • immunocytochemistry; human
  • flow cytometry; mouse
  • immunocytochemistry; mouse
Turaç G, Hindley C, Thomas R, Davis J, Deleidi M, Gasser T, et al. Combined flow cytometric analysis of surface and intracellular antigens reveals surface molecule markers of human neuropoiesis. PLoS ONE. 2013;8:e68519 pubmed publisher
  • immunocytochemistry; human; 1:500
Kao C, Hsu Y, Liu J, Lee D, Chung Y, Chiu I. The mood stabilizer valproate activates human FGF1 gene promoter through inhibiting HDAC and GSK-3 activities. J Neurochem. 2013;126:4-18 pubmed publisher
  • immunocytochemistry; human; 1:500
  • western blot; human; 1:3000
Arsenault J, Ferrari E, Niranjan D, Cuijpers S, Gu C, Vallis Y, et al. Stapling of the botulinum type A protease to growth factors and neuropeptides allows selective targeting of neuroendocrine cells. J Neurochem. 2013;126:223-33 pubmed publisher
  • immunocytochemistry; human; 1:1.000
Carra E, Barbieri F, Marubbi D, Pattarozzi A, Favoni R, Florio T, et al. Sorafenib selectively depletes human glioblastoma tumor-initiating cells from primary cultures. Cell Cycle. 2013;12:491-500 pubmed publisher
Shlevkov E, Basu H, Bray M, Sun Z, Wei W, Apaydin K, et al. A High-Content Screen Identifies TPP1 and Aurora B as Regulators of Axonal Mitochondrial Transport. Cell Rep. 2019;28:3224-3237.e5 pubmed publisher
Bieri G, Brahic M, Bousset L, Couthouis J, Kramer N, Ma R, et al. LRRK2 modifies α-syn pathology and spread in mouse models and human neurons. Acta Neuropathol. 2019;137:961-980 pubmed publisher
Hermes D, Xu C, Poklis J, Niphakis M, Cravatt B, Mackie K, et al. Neuroprotective effects of fatty acid amide hydrolase catabolic enzyme inhibition in a HIV-1 Tat model of neuroAIDS. Neuropharmacology. 2018;141:55-65 pubmed publisher
Kramer N, Haney M, Morgens D, Jovicic A, Couthouis J, Li A, et al. CRISPR-Cas9 screens in human cells and primary neurons identify modifiers of C9ORF72 dipeptide-repeat-protein toxicity. Nat Genet. 2018;50:603-612 pubmed publisher
Yan L, Li Y, Shi Z, Lu X, Ma J, Hu B, et al. The zinc finger E-box-binding homeobox 1 (Zeb1) promotes the conversion of mouse fibroblasts into functional neurons. J Biol Chem. 2017;292:12959-12970 pubmed publisher
Latina V, Caioli S, Zona C, Ciotti M, Amadoro G, Calissano P. Impaired NGF/TrkA Signaling Causes Early AD-Linked Presynaptic Dysfunction in Cholinergic Primary Neurons. Front Cell Neurosci. 2017;11:68 pubmed publisher
Flores B, Dulchavsky M, Krans A, Sawaya M, Paulson H, Todd P, et al. Distinct C9orf72-Associated Dipeptide Repeat Structures Correlate with Neuronal Toxicity. PLoS ONE. 2016;11:e0165084 pubmed publisher
Cortes D, Robledo Arratia Y, Hernández Martinez R, Escobedo Ávila I, Bargas J, Velasco I. Transgenic GDNF Positively Influences Proliferation, Differentiation, Maturation and Survival of Motor Neurons Produced from Mouse Embryonic Stem Cells. Front Cell Neurosci. 2016;10:217 pubmed publisher
Pellett S, Schwartz M, Tepp W, Josephson R, Scherf J, Pier C, et al. Human Induced Pluripotent Stem Cell Derived Neuronal Cells Cultured on Chemically-Defined Hydrogels for Sensitive In Vitro Detection of Botulinum Neurotoxin. Sci Rep. 2015;5:14566 pubmed publisher
Grande V, Manassero G, Vercelli A. Neuroprotective and anti-inflammatory roles of the phosphatase and tensin homolog deleted on chromosome Ten (PTEN) Inhibition in a Mouse Model of Temporal Lobe Epilepsy. PLoS ONE. 2014;9:e114554 pubmed publisher
Larios J, Jausoro I, Benítez M, Bronfman F, Marzolo M. Neurotrophins regulate ApoER2 proteolysis through activation of the Trk signaling pathway. BMC Neurosci. 2014;15:108 pubmed publisher
Dixon Salazar T, Fourgeaud L, Tyler C, Poole J, Park J, Boulanger L. MHC class I limits hippocampal synapse density by inhibiting neuronal insulin receptor signaling. J Neurosci. 2014;34:11844-56 pubmed publisher
Sanders L, McCoy J, Hu X, Mastroberardino P, Dickinson B, Chang C, et al. Mitochondrial DNA damage: molecular marker of vulnerable nigral neurons in Parkinson's disease. Neurobiol Dis. 2014;70:214-23 pubmed publisher
Coimbra J, Collin S, Hart N. Topographic specializations in the retinal ganglion cell layer of Australian passerines. J Comp Neurol. 2014;522:3609-28 pubmed publisher
Griffin S, Brinkman N, Hedrick E, Rhodes E, Fout G. Comparison of nucleic acid extraction and reverse transcription-qPCR approaches for detection of GI and GII noroviruses in drinking water. J Virol Methods. 2014;199:76-85 pubmed publisher
Hovakimyan M, Meyer A, Lukas J, Luo J, Gudziol V, Hummel T, et al. Olfactory deficits in Niemann-Pick type C1 (NPC1) disease. PLoS ONE. 2013;8:e82216 pubmed publisher
Leusch F, Khan S, Gagnon M, Quayle P, Trinh T, Coleman H, et al. Assessment of wastewater and recycled water quality: a comparison of lines of evidence from in vitro, in vivo and chemical analyses. Water Res. 2014;50:420-31 pubmed publisher
Chan W, Sideris A, Sutachan J, Montoya G J, Blanck T, Recio Pinto E. Differential regulation of proliferation and neuronal differentiation in adult rat spinal cord neural stem/progenitors by ERK1/2, Akt, and PLC?. Front Mol Neurosci. 2013;6:23 pubmed publisher
Novaes J, Carvalho E. Reproduction, food dynamics and exploitation level of Oreochromis niloticus (Perciformes: Cichlidae) from artisanal fisheries in Barra Bonita Reservoir, Brazil. Rev Biol Trop. 2012;60:721-34 pubmed
Masclaux F, Hotz P, Friedli D, Savova Bianchi D, Oppliger A. High occurrence of hepatitis E virus in samples from wastewater treatment plants in Switzerland and comparison with other enteric viruses. Water Res. 2013;47:5101-9 pubmed publisher
Li L, Ginet V, Liu X, Vergun O, Tuittila M, Mathieu M, et al. The nNOS-p38MAPK pathway is mediated by NOS1AP during neuronal death. J Neurosci. 2013;33:8185-201 pubmed publisher
Chung C, Fujita N, Kawahara N, Yui S, Nam E, Nishimura R. A comparison of neurosphere differentiation potential of canine bone marrow-derived mesenchymal stem cells and adipose-derived mesenchymal stem cells. J Vet Med Sci. 2013;75:879-86 pubmed
Xu J, Nonogaki M, Madhira R, Ma H, Hermanson O, Kioussi C, et al. Population-specific regulation of Chmp2b by Lbx1 during onset of synaptogenesis in lateral association interneurons. PLoS ONE. 2012;7:e48573 pubmed publisher
Nair R, Lauks J, Jung S, Cooke N, de Wit H, Brose N, et al. Neurobeachin regulates neurotransmitter receptor trafficking to synapses. J Cell Biol. 2013;200:61-80 pubmed publisher
Tapias V, Greenamyre J, Watkins S. Automated imaging system for fast quantitation of neurons, cell morphology and neurite morphometry in vivo and in vitro. Neurobiol Dis. 2013;54:158-68 pubmed publisher
De Keuckelaere A, Baert L, Duarte A, Stals A, Uyttendaele M. Evaluation of viral concentration methods from irrigation and processing water. J Virol Methods. 2013;187:294-303 pubmed publisher
Furutani Y, Kawasaki M, Matsuno H, Mitsui S, Mori K, Yoshihara Y. Vitronectin induces phosphorylation of ezrin/radixin/moesin actin-binding proteins through binding to its novel neuronal receptor telencephalin. J Biol Chem. 2012;287:39041-9 pubmed publisher
Karnas D, Mordel J, Bonnet D, Pevet P, Hicks D, Meissl H. Heterogeneity of intrinsically photosensitive retinal ganglion cells in the mouse revealed by molecular phenotyping. J Comp Neurol. 2013;521:912-32 pubmed publisher
Cai W, Carlson S, Brelsfoard J, Mannon C, Moncman C, Saatman K, et al. Rit GTPase signaling promotes immature hippocampal neuronal survival. J Neurosci. 2012;32:9887-97 pubmed publisher
Seidl A, Sanchez J, Schecterson L, Tabor K, Wang Y, Kashima D, et al. Transgenic quail as a model for research in the avian nervous system: a comparative study of the auditory brainstem. J Comp Neurol. 2013;521:5-23 pubmed publisher
Shi Y, Yuan S, Li B, Wang J, Carlton S, Chung K, et al. Regulation of Wnt signaling by nociceptive input in animal models. Mol Pain. 2012;8:47 pubmed publisher
Pruunsild P, Timmusk T. Subcellular localization and transcription regulatory potency of KCNIP/Calsenilin/DREAM/KChIP proteins in cultured primary cortical neurons do not provide support for their role in CRE-dependent gene expression. J Neurochem. 2012;123:29-43 pubmed publisher
Dever S, Xu R, Fitting S, Knapp P, Hauser K. Differential expression and HIV-1 regulation of ?-opioid receptor splice variants across human central nervous system cell types. J Neurovirol. 2012;18:181-90 pubmed publisher
Koch P, Tamboli I, Mertens J, Wunderlich P, Ladewig J, Stüber K, et al. Presenilin-1 L166P mutant human pluripotent stem cell-derived neurons exhibit partial loss of ?-secretase activity in endogenous amyloid-? generation. Am J Pathol. 2012;180:2404-16 pubmed publisher
Wu C, Yin J, Hwang C, Chen S, Yang D, Yang D. c-Jun-dependent sulfiredoxin induction mediates BDNF protection against mitochondrial inhibition in rat cortical neurons. Neurobiol Dis. 2012;46:450-62 pubmed publisher
Oukarroum A, Perreault F, Popovic R. Interactive effects of temperature and copper on photosystem II photochemistry in Chlorella vulgaris. J Photochem Photobiol B. 2012;110:9-14 pubmed publisher
Corrêa A, Rigotto C, Moresco V, Kleemann C, Teixeira A, Poli C, et al. The depuration dynamics of oysters (Crassostrea gigas) artificially contaminated with hepatitis A virus and human adenovirus. Mem Inst Oswaldo Cruz. 2012;107:11-7 pubmed
Abramowski D, Rabe S, Upadhaya A, Reichwald J, Danner S, Staab D, et al. Transgenic expression of intraneuronal A?42 but not A?40 leads to cellular A? lesions, degeneration, and functional impairment without typical Alzheimer's disease pathology. J Neurosci. 2012;32:1273-83 pubmed publisher
Killian R, Flippin J, Herrera C, Almenar Queralt A, Goldstein L. Kinesin light chain 1 suppression impairs human embryonic stem cell neural differentiation and amyloid precursor protein metabolism. PLoS ONE. 2012;7:e29755 pubmed publisher
Jaarsma D, van der Pluijm I, de Waard M, Haasdijk E, Brandt R, Vermeij M, et al. Age-related neuronal degeneration: complementary roles of nucleotide excision repair and transcription-coupled repair in preventing neuropathology. PLoS Genet. 2011;7:e1002405 pubmed publisher
Oukarroum A, Polchtchikov S, Perreault F, Popovic R. Temperature influence on silver nanoparticles inhibitory effect on photosystem II photochemistry in two green algae, Chlorella vulgaris and Dunaliella tertiolecta. Environ Sci Pollut Res Int. 2012;19:1755-62 pubmed publisher
Xing S, Zhang Y, Li J, Zhang J, Li Y, Dang C, et al. Beclin 1 knockdown inhibits autophagic activation and prevents the secondary neurodegenerative damage in the ipsilateral thalamus following focal cerebral infarction. Autophagy. 2012;8:63-76 pubmed publisher
Podhaizer E, Zou S, Fitting S, Samano K, El Hage N, Knapp P, et al. Morphine and gp120 toxic interactions in striatal neurons are dependent on HIV-1 strain. J Neuroimmune Pharmacol. 2012;7:877-91 pubmed publisher
Suzuki M, El Hage N, Zou S, Hahn Y, Sorrell M, Sturgill J, et al. Fractalkine/CX3CL1 protects striatal neurons from synergistic morphine and HIV-1 Tat-induced dendritic losses and death. Mol Neurodegener. 2011;6:78 pubmed publisher
Kroehne V, Freudenreich D, Hans S, Kaslin J, Brand M. Regeneration of the adult zebrafish brain from neurogenic radial glia-type progenitors. Development. 2011;138:4831-41 pubmed publisher
Borgesius N, de Waard M, van der Pluijm I, Omrani A, Zondag G, van der Horst G, et al. Accelerated age-related cognitive decline and neurodegeneration, caused by deficient DNA repair. J Neurosci. 2011;31:12543-53 pubmed publisher
Lauritzen F, Perez E, Melillo E, Roh J, Zaveri H, Lee T, et al. Altered expression of brain monocarboxylate transporter 1 in models of temporal lobe epilepsy. Neurobiol Dis. 2012;45:165-76 pubmed publisher
Rhodes E, Hamilton D, See M, Wymer L. Evaluation of hollow-fiber ultrafiltration primary concentration of pathogens and secondary concentration of viruses from water. J Virol Methods. 2011;176:38-45 pubmed publisher
Tucker A, Driskell L, Pannell L, Wood D. Differential proteomic analysis of Rickettsia prowazekii propagated in diverse host backgrounds. Appl Environ Microbiol. 2011;77:4712-8 pubmed publisher
Melzer T, Cranston H, Weiss L, Halonen S. Host Cell Preference of Toxoplasma gondii Cysts in Murine Brain: A Confocal Study. J Neuroparasitology. 2010;1: pubmed
Li Y, Tian C, Yang Y, Yan Y, Ni Y, Wei Y, et al. An inducible transgenic Cre mouse line for the study of hippocampal development and adult neurogenesis. Genesis. 2011;49:919-26 pubmed publisher
Novaes J, Carvalho E. Population structure and stock assessment of Hoplias malabaricus (Characiformes: Erythrinidae) caught by artisanal fishermen in river-reservoir transition area in Brazil. Rev Biol Trop. 2011;59:71-83 pubmed
Odraska P, Dolezalova L, Piler P, Oravec M, Blaha L. Utilization of the solid sorbent media in monitoring of airborne cyclophosphamide concentrations and the implications for occupational hygiene. J Environ Monit. 2011;13:1480-7 pubmed publisher
Cheng I, Lin Y, Hwang E, Huang H, Chang W, Liu Y, et al. Collagen VI protects against neuronal apoptosis elicited by ultraviolet irradiation via an Akt/phosphatidylinositol 3-kinase signaling pathway. Neuroscience. 2011;183:178-88 pubmed publisher
Aroeira R, Ribeiro J, Sebastião A, Valente C. Age-related changes of glycine receptor at the rat hippocampus: from the embryo to the adult. J Neurochem. 2011;118:339-53 pubmed publisher
Perreault F, Dionne J, Didur O, Juneau P, Popovic R. Effect of cadmium on photosystem II activity in Chlamydomonas reinhardtii: alteration of O-J-I-P fluorescence transients indicating the change of apparent activation energies within photosystem II. Photosynth Res. 2011;107:151-7 pubmed publisher
Alvarez Flores M, Furlin D, Ramos O, Balan A, Konno K, Chudzinski Tavassi A. Losac, the first hemolin that exhibits procogulant activity through selective factor X proteolytic activation. J Biol Chem. 2011;286:6918-28 pubmed publisher
Tabor K, Wong R, Rubel E. Topography and morphology of the inhibitory projection from superior olivary nucleus to nucleus laminaris in chickens (Gallus gallus). J Comp Neurol. 2011;519:358-75 pubmed publisher
Leao K, Leao R, Deardorff A, Garrett A, Fyffe R, Walmsley B. Sound stimulation modulates high-threshold K(+) currents in mouse auditory brainstem neurons. Eur J Neurosci. 2010;32:1658-67 pubmed publisher
Webster M, Elashoff M, Weickert C. Molecular evidence that cortical synaptic growth predominates during the first decade of life in humans. Int J Dev Neurosci. 2011;29:225-36 pubmed publisher
Perreault F, Dewez D, Fortin C, Juneau P, Diallo A, Popovic R. Effect of aluminum on cellular division and photosynthetic electron transport in Euglena gracilis and Chlamydomonas acidophila. Environ Toxicol Chem. 2010;29:887-92 pubmed publisher
Peng S, Lai Y, Huang H, Huang H, Huang Y. A novel role of CPEB3 in regulating EGFR gene transcription via association with Stat5b in neurons. Nucleic Acids Res. 2010;38:7446-57 pubmed publisher
Wu C, Chen S, Yin J, Hwang C, Yang D. Erythropoietin and sonic hedgehog mediate the neuroprotective effects of brain-derived neurotrophic factor against mitochondrial inhibition. Neurobiol Dis. 2010;40:146-54 pubmed publisher
Terauchi A, Peers G, Kobayashi M, Niyogi K, Merchant S. Trophic status of Chlamydomonas reinhardtii influences the impact of iron deficiency on photosynthesis. Photosynth Res. 2010;105:39-49 pubmed publisher
Hattori K, Kajimura M, Hishiki T, Nakanishi T, Kubo A, Nagahata Y, et al. Paradoxical ATP elevation in ischemic penumbra revealed by quantitative imaging mass spectrometry. Antioxid Redox Signal. 2010;13:1157-67 pubmed publisher
Spigolon G, Veronesi C, Bonny C, Vercelli A. c-Jun N-terminal kinase signaling pathway in excitotoxic cell death following kainic acid-induced status epilepticus. Eur J Neurosci. 2010;31:1261-72 pubmed publisher
Petit A, Eullaffroy P, Debenest T, Gagné F. Toxicity of PAMAM dendrimers to Chlamydomonas reinhardtii. Aquat Toxicol. 2010;100:187-93 pubmed publisher
Dosnon Olette R, Trotel Aziz P, Couderchet M, Eullaffroy P. Fungicides and herbicide removal in Scenedesmus cell suspensions. Chemosphere. 2010;79:117-23 pubmed publisher
Jiang Z, Belforte J, Lu Y, Yabe Y, Pickel J, Smith C, et al. eIF2alpha Phosphorylation-dependent translation in CA1 pyramidal cells impairs hippocampal memory consolidation without affecting general translation. J Neurosci. 2010;30:2582-94 pubmed publisher
Sangoi A, McKenney J. A tissue microarray-based comparative analysis of novel and traditional immunohistochemical markers in the distinction between adrenal cortical lesions and pheochromocytoma. Am J Surg Pathol. 2010;34:423-32 pubmed publisher
Samuel J, Hendrix L. Laboratory maintenance of Coxiella burnetii. Curr Protoc Microbiol. 2009;Chapter 6:Unit 6C.1 pubmed publisher
Tsuruta F, Green E, Rousset M, Dolmetsch R. PIKfyve regulates CaV1.2 degradation and prevents excitotoxic cell death. J Cell Biol. 2009;187:279-94 pubmed publisher
Chu Y, Brown P, Lyle B, Chen Y, Black R, Williams C, et al. Roasted coffees high in lipophilic antioxidants and chlorogenic acid lactones are more neuroprotective than green coffees. J Agric Food Chem. 2009;57:9801-8 pubmed publisher
Krishnan C, Higgins J, West R, Natkunam Y, Heerema McKenney A, Arber D. Microtubule-associated protein-2 is a sensitive marker of primary and metastatic neuroblastoma. Am J Surg Pathol. 2009;33:1695-704 pubmed publisher
Hozumi Y, Watanabe M, Otani K, Goto K. Diacylglycerol kinase beta promotes dendritic outgrowth and spine maturation in developing hippocampal neurons. BMC Neurosci. 2009;10:99 pubmed publisher
Diez J, Caballero S, Belda F, Otegui M, Gajardo R, Jorquera J. Elimination capacity of a TSE-model agent in the manufacturing process of Alphanate/Fanhdi, a human factor VIII/VWF complex concentrate. Haemophilia. 2009;15:1249-57 pubmed publisher
Kuleshova L, Tan F, Magalhaes R, Gouk S, Lee K, Dawe G. Effective cryopreservation of neural stem or progenitor cells without serum or proteins by vitrification. Cell Transplant. 2009;18:135-44 pubmed
Nogueira P, Melão M, Lombardi A, Nogueira M, Vieira A. The effects of Anabaena spiroides exopolysaccharides on copper accumulation in an aquatic food chain. Aquat Toxicol. 2009;93:125-30 pubmed publisher
Wu C, Hwang C, Yang D. Protective effects of brain-derived neurotrophic factor against neurotoxicity of 3-nitropropionic acid in rat cortical neurons. Neurotoxicology. 2009;30:718-26 pubmed publisher
Perreault F, Ait Ali N, Saison C, Popovic R, Juneau P. Dichromate effect on energy dissipation of photosystem II and photosystem I in Chlamydomonas reinhardtii. J Photochem Photobiol B. 2009;96:24-9 pubmed publisher
Leonard B, Mastroeni D, Grover A, Liu Q, Yang K, Gao M, et al. Subventricular zone neural progenitors from rapid brain autopsies of elderly subjects with and without neurodegenerative disease. J Comp Neurol. 2009;515:269-94 pubmed publisher
Wu C, Chen S, Hwang C, Yang D. Sonic hedgehog mediates BDNF-induced neuroprotection against mitochondrial inhibitor 3-nitropropionic acid. Biochem Biophys Res Commun. 2009;385:112-7 pubmed publisher
Defaux A, Zurich M, Braissant O, Honegger P, Monnet Tschudi F. Effects of the PPAR-beta agonist GW501516 in an in vitro model of brain inflammation and antibody-induced demyelination. J Neuroinflammation. 2009;6:15 pubmed publisher
Shan X, Vocadlo D, Krieger C. Mislocalization of TDP-43 in the G93A mutant SOD1 transgenic mouse model of ALS. Neurosci Lett. 2009;458:70-4 pubmed publisher
Francesconi A, Kumari R, Zukin R. Regulation of group I metabotropic glutamate receptor trafficking and signaling by the caveolar/lipid raft pathway. J Neurosci. 2009;29:3590-602 pubmed publisher
Janex Habibi M, Huyard A, Esperanza M, Bruchet A. Reduction of endocrine disruptor emissions in the environment: the benefit of wastewater treatment. Water Res. 2009;43:1565-76 pubmed publisher
Toyoshima M, Sakurai K, Shimazaki K, Takeda Y, Nakamoto M, Serizawa S, et al. Preferential localization of neural cell recognition molecule NB-2 in developing glutamatergic neurons in the rat auditory brainstem. J Comp Neurol. 2009;513:349-62 pubmed publisher
Nogueira P, Melão M, Lombardi A, Nogueira M. Natural DOM affects copper speciation and bioavailability to bacteria and ciliate. Arch Environ Contam Toxicol. 2009;57:274-81 pubmed publisher
Ramamoorthy P, Whim M. Trafficking and fusion of neuropeptide Y-containing dense-core granules in astrocytes. J Neurosci. 2008;28:13815-27 pubmed publisher
Hozumi Y, Fukaya M, Adachi N, Saito N, Otani K, Kondo H, et al. Diacylglycerol kinase beta accumulates on the perisynaptic site of medium spiny neurons in the striatum. Eur J Neurosci. 2008;28:2409-22 pubmed publisher
Gu X, He D, Li Y, Hu C, Wei Y, Liu G, et al. Generation of Frizzled10-Cre transgenic mouse line: a useful tool for the study of dorsal telencephalic development. Genesis. 2008;46:523-9 pubmed publisher
Ponti G, Peretto P, Bonfanti L. Genesis of neuronal and glial progenitors in the cerebellar cortex of peripuberal and adult rabbits. PLoS ONE. 2008;3:e2366 pubmed publisher
Liu J, Rumsey J, Das M, Molnar P, Gregory C, Riedel L, et al. Electrophysiological and immunocytochemical characterization of DRG neurons on an organosilane surface in serum-free medium. In Vitro Cell Dev Biol Anim. 2008;44:162-8 pubmed publisher
Yokoo S, Yamagami S, Shimada T, Usui T, Sato T, Amano S, et al. A novel isolation technique of progenitor cells in human corneal epithelium using non-tissue culture dishes. Stem Cells. 2008;26:1743-8 pubmed publisher
Lelouvier B, Tamagno G, Kaindl A, Roland A, Lelievre V, Le Verche V, et al. Dynamics of somatostatin type 2A receptor cargoes in living hippocampal neurons. J Neurosci. 2008;28:4336-49 pubmed publisher
Ladewig J, Koch P, Endl E, Meiners B, Opitz T, Couillard Despres S, et al. Lineage selection of functional and cryopreservable human embryonic stem cell-derived neurons. Stem Cells. 2008;26:1705-12 pubmed publisher
Braissant O, Cagnon L, Monnet Tschudi F, Speer O, Wallimann T, Honegger P, et al. Ammonium alters creatine transport and synthesis in a 3D culture of developing brain cells, resulting in secondary cerebral creatine deficiency. Eur J Neurosci. 2008;27:1673-85 pubmed publisher
Diniz Mendes L, Paula V, Luz S, Niel C. High prevalence of human Torque teno virus in streams crossing the city of Manaus, Brazilian Amazon. J Appl Microbiol. 2008;105:51-8 pubmed publisher
Huang C, Yang H, Chen S, Shaw F, Yang D. Protective effects of lipopolysaccharide preconditioning against nitric oxide neurotoxicity. J Neurosci Res. 2008;86:1277-89 pubmed
Miagostovich M, Ferreira F, Guimarães F, Fumian T, Diniz Mendes L, Luz S, et al. Molecular detection and characterization of gastroenteritis viruses occurring naturally in the stream waters of Manaus, central Amazonia, Brazil. Appl Environ Microbiol. 2008;74:375-82 pubmed
Pricelius S, Held C, Murkovic M, Bozic M, Kokol V, Cavaco Paulo A, et al. Enzymatic reduction of azo and indigoid compounds. Appl Microbiol Biotechnol. 2007;77:321-7 pubmed
Ait Ali N, Juneau P, Didur O, Perreault F, Popovic R. Effect of dichromate on photosystem II activity in xanthophyll-deficient mutants of Chlamydomonas reinhardtii. Photosynth Res. 2008;95:45-53 pubmed
Estrela A, Seixas A, Termignoni C. A cysteine endopeptidase from tick (Rhipicephalus (Boophilus) microplus) larvae with vitellin digestion activity. Comp Biochem Physiol B Biochem Mol Biol. 2007;148:410-6 pubmed
Ichikawa J, Yamada R, Muramatsu R, Ikegaya Y, Matsuki N, Koyama R. Cryopreservation of granule cells from the postnatal rat hippocampus. J Pharmacol Sci. 2007;104:387-91 pubmed
Sage D, Salin P, Alcaraz G, Castets F, Giraud P, Crest M, et al. Na(v)1.7 and Na(v)1.3 are the only tetrodotoxin-sensitive sodium channels expressed by the adult guinea pig enteric nervous system. J Comp Neurol. 2007;504:363-78 pubmed
Raiteri L, Stigliani S, Usai C, Diaspro A, Paluzzi S, Milanese M, et al. Functional expression of release-regulating glycine transporters GLYT1 on GABAergic neurons and GLYT2 on astrocytes in mouse spinal cord. Neurochem Int. 2008;52:103-12 pubmed
Dewez D, Didur O, Vincent Héroux J, Popovic R. Validation of photosynthetic-fluorescence parameters as biomarkers for isoproturon toxic effect on alga Scenedesmus obliquus. Environ Pollut. 2008;151:93-100 pubmed
Fenrich K, Skelton N, MacDermid V, Meehan C, Armstrong S, Neuber Hess M, et al. Axonal regeneration and development of de novo axons from distal dendrites of adult feline commissural interneurons after a proximal axotomy. J Comp Neurol. 2007;502:1079-97 pubmed
Francis J, Olariu A, Kobayashi E, Leone P. GFP-transgenic Lewis rats as a cell source for oligodendrocyte replacement. Exp Neurol. 2007;205:177-89 pubmed
Garcia Espinosa M, Wallin R, Hutson S, Sweatt A. Widespread neuronal expression of branched-chain aminotransferase in the CNS: implications for leucine/glutamate metabolism and for signaling by amino acids. J Neurochem. 2007;100:1458-68 pubmed
Sano Y, Nakaya T, Pedrini S, Takeda S, Iijima Ando K, Iijima K, et al. Physiological mouse brain Abeta levels are not related to the phosphorylation state of threonine-668 of Alzheimer's APP. PLoS ONE. 2006;1:e51 pubmed
Hasegawa A, Naruse M, Hitoshi S, Iwasaki Y, Takebayashi H, Ikenaka K. Regulation of glial development by cystatin C. J Neurochem. 2007;100:12-22 pubmed
Yoshikawa M, Nakajima K, Takayasu N, Noda S, Sato Y, Kawaguchi M, et al. Expression of the mRNA and protein of serine racemase in primary cultures of rat neurons. Eur J Pharmacol. 2006;548:74-6 pubmed
Fitzgerald D, Cole S, Hammond A, Seaman C, Cooper H. Characterization of neogenin-expressing neural progenitor populations and migrating neuroblasts in the embryonic mouse forebrain. Neuroscience. 2006;142:703-16 pubmed
Buxhoeveden D, Hasselrot U, Buxhoeveden N, Booze R, Mactutus C. Microanatomy in 21 day rat brains exposed prenatally to cocaine. Int J Dev Neurosci. 2006;24:335-41 pubmed
Peers G, Price N. Copper-containing plastocyanin used for electron transport by an oceanic diatom. Nature. 2006;441:341-4 pubmed
Carmena D, Martinez J, Benito A, Guisantes J. Shared and non-shared antigens from three different extracts of the metacestode of Echinococcus granulosus. Mem Inst Oswaldo Cruz. 2005;100:861-7 pubmed
Dubois E, Hennechart C, Deboosere N, Merle G, Legeay O, Burger C, et al. Intra-laboratory validation of a concentration method adapted for the enumeration of infectious F-specific RNA coliphage, enterovirus, and hepatitis A virus from inoculated leaves of salad vegetables. Int J Food Microbiol. 2006;108:164-71 pubmed
Shin J, Fang Z, Yu Z, Wang C, Li S, Li X. Expression of mutant huntingtin in glial cells contributes to neuronal excitotoxicity. J Cell Biol. 2005;171:1001-12 pubmed
Haney C, Buehler P, Gulati A. Synthesis and characterization of a novel DTPA polymerized hemoglobin based oxygen carrier. Biochim Biophys Acta. 2005;1725:358-69 pubmed
Platts Mills J, Custis N, Woodfolk J, Platts Mills T. Airborne endotoxin in homes with domestic animals: implications for cat-specific tolerance. J Allergy Clin Immunol. 2005;116:384-9 pubmed
Dewez D, Geoffroy L, Vernet G, Popovic R. Determination of photosynthetic and enzymatic biomarkers sensitivity used to evaluate toxic effects of copper and fludioxonil in alga Scenedesmus obliquus. Aquat Toxicol. 2005;74:150-9 pubmed
de Jesus Ribeiro C, Ohara M, Gama P. Alternative model to human skin organ culture: a preliminary study with Leibovitz L15 medium. Microsc Res Tech. 2005;66:139-44 pubmed
Pengchai P, Nakajima F, Furumai H. Estimation of origins of polycyclic aromatic hydrocarbons in size-fractionated road dust in Tokyo with multivariate analysis. Water Sci Technol. 2005;51:169-75 pubmed
Platts Mills J, Custis N, Kenney A, Tsay A, Chapman M, Feldman S, et al. The effects of cage design on airborne allergens and endotoxin in animal rooms: high-volume measurements with an ion-charging device. Contemp Top Lab Anim Sci. 2005;44:12-6 pubmed
Cowan A, Freeman M, Björkman P, Nicander B, Sitbon F, Tillberg E. Effects of senescence-induced alteration in cytokinin metabolism on source-sink relationships and ontogenic and stress-induced transitions in tobacco. Planta. 2005;221:801-14 pubmed
Wagenaar D, Madhavan R, Pine J, Potter S. Controlling bursting in cortical cultures with closed-loop multi-electrode stimulation. J Neurosci. 2005;25:680-8 pubmed
product information
Catalog Number :
MAB378
Subcategory :
Neuroscience
Product Name :
Anti-MAP2A Antibody, 2B
Product Type :
Antibodies
Clonality :
Monoclonal Antibody
Gene ID :
P11137
Host Name :
Mouse
Antigen :
MAP2A
Clone :
AP20
Conjugate :
Ascites
Isotype :
IgG1
Product Description :
Anti-MAP2A Antibody, 2B
Cross Reactivity :
Amphibian;Avian;Bovine;Human;Mouse;Rat;Xenopus;Quail
Background :
MAP-2 (microtubule associated protein-2) is on of several high molecular weight proteins that play an important role in brain microtubule assembly. In addition to its association with microtubules, MAP-2 associates with neurofilaments and actin filaments suggesting that it may guide interaction among microtubules, other cytoskeletal elements, and cytoplasmic organelles (Binder, 1984). MAP-2 is a stringent marker for neurons. In addition, MAP-2 displays intracellular specificity. In the central nervous system, MAP-2 is confined to neuronal cell bodies and dendrites. There are exceptions, however, where some axons stain positive for small amounts of MAP-2 (Caceres, 1984; Binder, 1986). MAP-2 is uniformly distributed throughout the cell when first expressed in cultured neurons but becomes selectively localized as dendritic development proceeds (Caceres, 1986; Dotti, 1987).
ALT Names :
Microtubule Associated Protein 2
Immunogen :
Bovine MAP2
Specificity :
MAP2a & b. Does not recognize other variants.
Package Size :
100 µL
Uses :
Immunohistochemistry;Western Blotting
Storage :
Stable for 1 year at -20ºC in undiluted aliquots from date of receipt. Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.
company information
EMD Millipore
290 Concord Road
Billerica, Massachusetts 01821
bioscienceshelp@emdchemical.com
https://www.emdmillipore.com
888-854-3417
headquarters: United States
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

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