This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
EMD Millipore
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
product type :
antibody
product name :
NeuN Antibody, clone A60, biotin conjugated
catalog :
MAB377B
quantity :
500 µg
clonality :
monoclonal
host :
mouse
conjugate :
biotin
clone name :
A60

The same clone is also sold as:
reactivity :
grey mouse lemur, human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, immunohistochemistry - free floating section
citations: 85
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - frozen section; grey mouse lemur; 1:5000
Saraf M, Balaram P, Pifferi F, Kennedy H, Kaas J. The sensory thalamus and visual midbrain in mouse lemurs. J Comp Neurol. 2019;527:2599-2611 pubmed publisher
  • immunohistochemistry; grey mouse lemur; 1:5000; loading ...; fig 5e
Saraf M, Balaram P, Pifferi F, Gămănuţ R, Kennedy H, Kaas J. Architectonic features and relative locations of primary sensory and related areas of neocortex in mouse lemurs. J Comp Neurol. 2019;527:625-639 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:200; fig 4f
Segarra M, Aburto M, Cop F, Llaó Cid C, Härtl R, Damm M, et al. Endothelial Dab1 signaling orchestrates neuro-glia-vessel communication in the central nervous system. Science. 2018;361: pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:100; fig s1
Vasek M, Garber C, Dorsey D, Durrant D, Bollman B, Soung A, et al. A complement-microglial axis drives synapse loss during virus-induced memory impairment. Nature. 2016;534:538-43 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:500; loading ...; fig 2a, 3c
Fan W, Li X, Yao H, Deng J, Liu H, Cui Z, et al. Neural differentiation and synaptogenesis in retinal development. Neural Regen Res. 2016;11:312-8 pubmed publisher
  • immunohistochemistry; mouse; 1:300; loading ...; fig 2b
Hilbers F, Kopeć W, Isaksen T, Holm T, Lykke Hartmann K, Nissen P, et al. Tuning of the Na,K-ATPase by the beta subunit. Sci Rep. 2016;6:20442 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig 2a
Dahlke C, Saberi D, Ott B, Brand Saberi B, Schmitt John T, Theiss C. Inflammation and neuronal death in the motor cortex of the wobbler mouse, an ALS animal model. J Neuroinflammation. 2015;12:215 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:500; loading ...; fig 4a
Wu H, Yang S, Dai J, Qiu Y, Miao Y, Zhang X. Combination of early and delayed ischemic postconditioning enhances brain-derived neurotrophic factor production by upregulating the ERK-CREB pathway in rats with focal ischemia. Mol Med Rep. 2015;12:6427-34 pubmed publisher
  • flow cytometry; rat; 1:1000
Rubio F, Liu Q, Li X, Cruz F, Leão R, Warren B, et al. Context-induced reinstatement of methamphetamine seeking is associated with unique molecular alterations in Fos-expressing dorsolateral striatum neurons. J Neurosci. 2015;35:5625-39 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 4a
Doyle K, Quach L, Arceuil H, Buckwalter M. Ferumoxytol administration does not alter infarct volume or the inflammatory response to stroke in mice. Neurosci Lett. 2015;584:236-40 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:500
Wimmer V, Harty R, Richards K, Phillips A, Miyazaki H, Nukina N, et al. Sodium channel β1 subunit localizes to axon initial segments of excitatory and inhibitory neurons and shows regional heterogeneity in mouse brain. J Comp Neurol. 2015;523:814-30 pubmed publisher
  • immunohistochemistry; mouse; 1:500
Wang Z, Deng T, Deng J, Deng J, Gao X, Shi Y, et al. Ceramide is involved in alcohol-induced neural proliferation. Neural Regen Res. 2013;8:2178-89 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:200
Cekanaviciute E, Dietrich H, Axtell R, Williams A, Egusquiza R, Wai K, et al. Astrocytic TGF-? signaling limits inflammation and reduces neuronal damage during central nervous system Toxoplasma infection. J Immunol. 2014;193:139-49 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:500
Howerton A, Roland A, Bale T. Dorsal raphe neuroinflammation promotes dramatic behavioral stress dysregulation. J Neurosci. 2014;34:7113-23 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:200
Cekanaviciute E, Fathali N, Doyle K, Williams A, Han J, Buckwalter M. Astrocytic transforming growth factor-beta signaling reduces subacute neuroinflammation after stroke in mice. Glia. 2014;62:1227-40 pubmed publisher
  • immunocytochemistry; mouse; 1:500
Cui Z, Deng J, Zhao K, Yu D, Hu S, Shi S, et al. Effects of chronic cold exposure on murine central nervous system. J Neurosci Res. 2014;92:496-505 pubmed publisher
  • immunohistochemistry; mouse; 1:250
Aschauer D, Kreuz S, Rumpel S. Analysis of transduction efficiency, tropism and axonal transport of AAV serotypes 1, 2, 5, 6, 8 and 9 in the mouse brain. PLoS ONE. 2013;8:e76310 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:50
Prox J, Bernreuther C, Altmeppen H, Grendel J, Glatzel M, D Hooge R, et al. Postnatal disruption of the disintegrin/metalloproteinase ADAM10 in brain causes epileptic seizures, learning deficits, altered spine morphology, and defective synaptic functions. J Neurosci. 2013;33:12915-28, 12928a pubmed publisher
  • immunohistochemistry - free floating section; mouse; 1:500-1:1,000
Wootz H, Fitzsimons Kantamneni E, Larhammar M, Rotterman T, Enjin A, Patra K, et al. Alterations in the motor neuron-renshaw cell circuit in the Sod1(G93A) mouse model. J Comp Neurol. 2013;521:1449-69 pubmed publisher
Blair L, Criado Marrero M, Zheng D, Wang X, Kamath S, Nordhues B, et al. The Disease-Associated Chaperone FKBP51 Impairs Cognitive Function by Accelerating AMPA Receptor Recycling. Eneuro. 2019;6: pubmed publisher
Wang B, Joo J, Mount R, Teubner B, Krenzer A, Ward A, et al. The COPII cargo adapter SEC24C is essential for neuronal homeostasis. J Clin Invest. 2018;128:3319-3332 pubmed publisher
Rayasam A, Hsu M, Kijak J, Kissel L, Hernandez G, Sandor M, et al. Immune responses in stroke: how the immune system contributes to damage and healing after stroke and how this knowledge could be translated to better cures?. Immunology. 2018;154:363-376 pubmed publisher
Shelton L, Baker J, Zheng D, Sullivan L, Solanki P, Webster J, et al. Hsp90 activator Aha1 drives production of pathological tau aggregates. Proc Natl Acad Sci U S A. 2017;114:9707-9712 pubmed publisher
Zhu Y, Vidaurre O, Adula K, Kezunovic N, Wentling M, Huntley G, et al. Subcellular Distribution of HDAC1 in Neurotoxic Conditions Is Dependent on Serine Phosphorylation. J Neurosci. 2017;37:7547-7559 pubmed publisher
Armbruster M, Hanson E, Dulla C. Glutamate Clearance Is Locally Modulated by Presynaptic Neuronal Activity in the Cerebral Cortex. J Neurosci. 2016;36:10404-10415 pubmed
Papale A, Morella I, Indrigo M, Bernardi R, Marrone L, Marchisella F, et al. Impairment of cocaine-mediated behaviours in mice by clinically relevant Ras-ERK inhibitors. elife. 2016;5: pubmed publisher
Mooney S, Shah K, Yeung S, Burgess A, Aubert I, Hynynen K. Focused Ultrasound-Induced Neurogenesis Requires an Increase in Blood-Brain Barrier Permeability. PLoS ONE. 2016;11:e0159892 pubmed publisher
Kovalska M, Kovalska L, Mikuskova K, Adamkov M, Tatarkova Z, Lehotsky J. p-ERK involvement in the neuroprotection exerted by ischemic preconditioning in rat hippocampus subjected to four vessel occlusion. J Physiol Pharmacol. 2014;65:767-76 pubmed
Lei Y, Thuault S, Launay P, Margolskee R, Kandel E, Siegelbaum S. Differential contribution of TRPM4 and TRPM5 nonselective cation channels to the slow afterdepolarization in mouse prefrontal cortex neurons. Front Cell Neurosci. 2014;8:267 pubmed publisher
Sweet T, Panda N, Hein A, Das S, Hurley S, Olschowka J, et al. Central nervous system effects of whole-body proton irradiation. Radiat Res. 2014;182:18-34 pubmed publisher
Nelson M, Tse T, O Quinn D, Percival S, Jaimes E, Warnock D, et al. Autophagy-lysosome pathway associated neuropathology and axonal degeneration in the brains of alpha-galactosidase A-deficient mice. Acta Neuropathol Commun. 2014;2:20 pubmed publisher
Kim H, Andreazza A, Yeung P, Isaacs Trepanier C, Young L. Oxidation and nitration in dopaminergic areas of the prefrontal cortex from patients with bipolar disorder and schizophrenia. J Psychiatry Neurosci. 2014;39:276-85 pubmed
Höglinger G, Arias Carrión O, Ipach B, Oertel W. Origin of the dopaminergic innervation of adult neurogenic areas. J Comp Neurol. 2014;522:2336-48 pubmed publisher
Rodriguez A, de Sevilla Müller L, Brecha N. The RNA binding protein RBPMS is a selective marker of ganglion cells in the mammalian retina. J Comp Neurol. 2014;522:1411-43 pubmed publisher
Raida Z, Hundahl C, Nyengaard J, Hay Schmidt A. Neuroglobin over expressing mice: expression pattern and effect on brain ischemic infarct size. PLoS ONE. 2013;8:e76565 pubmed publisher
Boulland J, Lambert F, Züchner M, Ström S, Glover J. A neonatal mouse spinal cord injury model for assessing post-injury adaptive plasticity and human stem cell integration. PLoS ONE. 2013;8:e71701 pubmed publisher
Apuschkin M, Ougaard M, Rekling J. Spontaneous calcium waves in granule cells in cerebellar slice cultures. Neurosci Lett. 2013;553:78-83 pubmed publisher
Liu Q, Rubio F, Bossert J, Marchant N, Fanous S, Hou X, et al. Detection of molecular alterations in methamphetamine-activated Fos-expressing neurons from a single rat dorsal striatum using fluorescence-activated cell sorting (FACS). J Neurochem. 2014;128:173-85 pubmed publisher
Chen Roetling J, Lu X, Regan K, Regan R. A rapid fluorescent method to quantify neuronal loss after experimental intracerebral hemorrhage. J Neurosci Methods. 2013;216:128-36 pubmed publisher
Fricks Gleason A, Keefe K. Evaluating the role of neuronal nitric oxide synthase-containing striatal interneurons in methamphetamine-induced dopamine neurotoxicity. Neurotox Res. 2013;24:288-97 pubmed publisher
Suberbielle E, Sanchez P, Kravitz A, Wang X, Ho K, Eilertson K, et al. Physiologic brain activity causes DNA double-strand breaks in neurons, with exacerbation by amyloid-?. Nat Neurosci. 2013;16:613-21 pubmed publisher
Brackett D, Qing F, Amieux P, Sellers D, Horner P, Morris D. FMR1 transcript isoforms: association with polyribosomes; regional and developmental expression in mouse brain. PLoS ONE. 2013;8:e58296 pubmed publisher
Birenboim R, Markus A, Goldstein R. Simple generation of neurons from human embryonic stem cells using agarose multiwell dishes. J Neurosci Methods. 2013;214:9-14 pubmed publisher
Michalski D, Hartig W, Krugel K, Edwards R, Böddener M, Böhme L, et al. Region-specific expression of vesicular glutamate and GABA transporters under various ischaemic conditions in mouse forebrain and retina. Neuroscience. 2013;231:328-44 pubmed publisher
Fanous S, Guez Barber D, Goldart E, Schrama R, Theberge F, Shaham Y, et al. Unique gene alterations are induced in FACS-purified Fos-positive neurons activated during cue-induced relapse to heroin seeking. J Neurochem. 2013;124:100-8 pubmed publisher
Morterá P, Herculano Houzel S. Age-related neuronal loss in the rat brain starts at the end of adolescence. Front Neuroanat. 2012;6:45 pubmed publisher
Leaver K, Reynolds A, Bodard S, Guilloteau D, Chalon S, Kassiou M. Effects of translocator protein (18 kDa) ligands on microglial activation and neuronal death in the quinolinic-acid-injected rat striatum. ACS Chem Neurosci. 2012;3:114-9 pubmed publisher
Urban E, Bury S, Barbay H, Guggenmos D, Dong Y, Nudo R. Gene expression changes of interconnected spared cortical neurons 7 days after ischemic infarct of the primary motor cortex in the rat. Mol Cell Biochem. 2012;369:267-86 pubmed publisher
Shrivastava K, Gonzalez P, Acarin L. The immune inhibitory complex CD200/CD200R is developmentally regulated in the mouse brain. J Comp Neurol. 2012;520:2657-75 pubmed publisher
Wu M, Hein A, Moravan M, Shaftel S, Olschowka J, O Banion M. Adult murine hippocampal neurogenesis is inhibited by sustained IL-1? and not rescued by voluntary running. Brain Behav Immun. 2012;26:292-300 pubmed publisher
Guez Barber D, Fanous S, Harvey B, Zhang Y, Lehrmann E, Becker K, et al. FACS purification of immunolabeled cell types from adult rat brain. J Neurosci Methods. 2012;203:10-8 pubmed publisher
De Repentigny Y, Ferrier A, Ryan S, Sato T, Kothary R. Motor unit abnormalities in Dystonia musculorum mice. PLoS ONE. 2011;6:e21093 pubmed publisher
Girolamo F, Ferrara G, Strippoli M, Rizzi M, Errede M, Trojano M, et al. Cerebral cortex demyelination and oligodendrocyte precursor response to experimental autoimmune encephalomyelitis. Neurobiol Dis. 2011;43:678-89 pubmed publisher
Rolyan H, Scheffold A, Heinrich A, Begus Nahrmann Y, Langkopf B, Holter S, et al. Telomere shortening reduces Alzheimer's disease amyloid pathology in mice. Brain. 2011;134:2044-56 pubmed publisher
Du X, Fleiss B, Li H, D Angelo B, Sun Y, Zhu C, et al. Systemic stimulation of TLR2 impairs neonatal mouse brain development. PLoS ONE. 2011;6:e19583 pubmed publisher
Chang C, Chen S, Lee T, Lee H, Chen S, Shyue S. Caveolin-1 deletion reduces early brain injury after experimental intracerebral hemorrhage. Am J Pathol. 2011;178:1749-61 pubmed publisher
Guez Barber D, Fanous S, Golden S, Schrama R, Koya E, Stern A, et al. FACS identifies unique cocaine-induced gene regulation in selectively activated adult striatal neurons. J Neurosci. 2011;31:4251-9 pubmed publisher
Lee M, Wang T, Jang M, Steiner J, Haughey N, Ming G, et al. Rescue of adult hippocampal neurogenesis in a mouse model of HIV neurologic disease. Neurobiol Dis. 2011;41:678-87 pubmed publisher
Siembab V, Smith C, Zagoraiou L, Berrocal M, Mentis G, Alvarez F. Target selection of proprioceptive and motor axon synapses on neonatal V1-derived Ia inhibitory interneurons and Renshaw cells. J Comp Neurol. 2010;518:4675-701 pubmed publisher
Zhang Y, Niu B, Yu D, Cheng X, Liu B, Deng J. Radial glial cells and the lamination of the cerebellar cortex. Brain Struct Funct. 2010;215:115-22 pubmed publisher
Benini R, Longo D, Biagini G, Avoli M. Perirhinal cortex hyperexcitability in pilocarpine-treated epileptic rats. Hippocampus. 2011;21:702-13 pubmed publisher
Duhem Tonnelle V, Bieche I, Vacher S, Loyens A, Maurage C, Collier F, et al. Differential distribution of erbB receptors in human glioblastoma multiforme: expression of erbB3 in CD133-positive putative cancer stem cells. J Neuropathol Exp Neurol. 2010;69:606-22 pubmed publisher
Wada M, Higo N, Moizumi S, Kitazawa S. c-Fos expression during temporal order judgment in mice. PLoS ONE. 2010;5:e10483 pubmed publisher
Wu X, Pan W, He Y, Hsuchou H, Kastin A. Cerebral interleukin-15 shows upregulation and beneficial effects in experimental autoimmune encephalomyelitis. J Neuroimmunol. 2010;223:65-72 pubmed publisher
Füchtbauer L, Toft Hansen H, Khorooshi R, Owens T. Expression of astrocytic type 2 angiotensin receptor in central nervous system inflammation correlates with blood-brain barrier breakdown. J Mol Neurosci. 2010;42:89-98 pubmed publisher
Matousek S, Hein A, Shaftel S, Olschowka J, Kyrkanides S, O Banion M. Cyclooxygenase-1 mediates prostaglandin E(2) elevation and contextual memory impairment in a model of sustained hippocampal interleukin-1beta expression. J Neurochem. 2010;114:247-58 pubmed publisher
Wulf Johansson H, Amrutkar D, Hay Schmidt A, Poulsen A, Klaerke D, Olesen J, et al. Localization of large conductance calcium-activated potassium channels and their effect on calcitonin gene-related peptide release in the rat trigemino-neuronal pathway. Neuroscience. 2010;167:1091-102 pubmed publisher
Li M, Cui Z, Niu Y, Liu B, Fan W, Yu D, et al. Synaptogenesis in the developing mouse visual cortex. Brain Res Bull. 2010;81:107-13 pubmed publisher
Hsuchou H, Pan W, Barnes M, Kastin A. Leptin receptor mRNA in rat brain astrocytes. Peptides. 2009;30:2275-80 pubmed publisher
Moore A, Wu M, Shaftel S, Graham K, O Banion M. Sustained expression of interleukin-1beta in mouse hippocampus impairs spatial memory. Neuroscience. 2009;164:1484-95 pubmed publisher
Bandeira F, Lent R, Herculano Houzel S. Changing numbers of neuronal and non-neuronal cells underlie postnatal brain growth in the rat. Proc Natl Acad Sci U S A. 2009;106:14108-13 pubmed publisher
Iourov I, Vorsanova S, Liehr T, Yurov Y. Aneuploidy in the normal, Alzheimer's disease and ataxia-telangiectasia brain: differential expression and pathological meaning. Neurobiol Dis. 2009;34:212-20 pubmed publisher
Hsuchou H, He Y, Kastin A, Tu H, Markadakis E, Rogers R, et al. Obesity induces functional astrocytic leptin receptors in hypothalamus. Brain. 2009;132:889-902 pubmed publisher
Azevedo F, Carvalho L, Grinberg L, Farfel J, Ferretti R, Leite R, et al. Equal numbers of neuronal and nonneuronal cells make the human brain an isometrically scaled-up primate brain. J Comp Neurol. 2009;513:532-41 pubmed publisher
Meyer R, Gehlhaus M, Schwab R, Bürck C, Knoth R, Hagemeyer C. Concordant up-regulation of cytochrome P450 Cyp3a11, testosterone oxidation and androgen receptor expression in mouse brain after xenobiotic treatment. J Neurochem. 2009;109:670-81 pubmed publisher
Mastroeni D, Grover A, Delvaux E, Whiteside C, Coleman P, Rogers J. Epigenetic changes in Alzheimer's disease: decrements in DNA methylation. Neurobiol Aging. 2010;31:2025-37 pubmed publisher
Yang Z, You Y, Levison S. Neonatal hypoxic/ischemic brain injury induces production of calretinin-expressing interneurons in the striatum. J Comp Neurol. 2008;511:19-33 pubmed publisher
Miles D, Kernie S. Hypoxic-ischemic brain injury activates early hippocampal stem/progenitor cells to replace vulnerable neuroblasts. Hippocampus. 2008;18:793-806 pubmed publisher
Segovia K, McClure M, Moravec M, Luo N, Wan Y, Gong X, et al. Arrested oligodendrocyte lineage maturation in chronic perinatal white matter injury. Ann Neurol. 2008;63:520-30 pubmed publisher
Yan X, Hou H, Wu L, Liu J, Zhou J. Lithium regulates hippocampal neurogenesis by ERK pathway and facilitates recovery of spatial learning and memory in rats after transient global cerebral ischemia. Neuropharmacology. 2007;53:487-95 pubmed
Kelsen J, Kjaer K, Chen G, Pedersen M, Røhl L, Frøkiaer J, et al. Parecoxib is neuroprotective in spontaneously hypertensive rats after transient middle cerebral artery occlusion: a divided treatment response?. J Neuroinflammation. 2006;3:31 pubmed
Genetta T, Lee B, Sola A. Low doses of ethanol and hypoxia administered together act synergistically to promote the death of cortical neurons. J Neurosci Res. 2007;85:131-8 pubmed
Soria J, Martínez Ramos C, Salmerón Sánchez M, Benavent V, Campillo Fernández A, Gómez Ribelles J, et al. Survival and differentiation of embryonic neural explants on different biomaterials. J Biomed Mater Res A. 2006;79:495-502 pubmed
Yoshioka M, Okada T, Inoue K, Kawai Y. Pattern differentiation of excitatory and inhibitory synaptic inputs on distinct neuronal types in the rat caudal nucleus of the tractus solitarius. Neurosci Res. 2006;55:300-15 pubmed
Meyer R, Hagemeyer C, Knoth R, Kaufmann M, Volk B. Anti-epileptic drug phenytoin enhances androgen metabolism and androgen receptor expression in murine hippocampus. J Neurochem. 2006;96:460-72 pubmed
product information
Catalog Number :
MAB377B
Subcategory :
Neuroscience
Product Name :
Anti-NeuN Antibody, clone A60, biotin conjugated
Product Type :
Antibodies
Clonality :
Monoclonal Antibody
Host Name :
Mouse
Antigen :
NeuN
Clone :
A60
Conjugate :
Biotin
Isotype :
IgG1
Product Description :
Anti-NeuN Antibody, clone A60, biotin conjugated
Cross Reactivity :
Mouse;Rat;Human;Ferret;Chicken;Salamander
Background :
NeuN antibody (NEUronal Nuclei; clone A60) specifically recognizes the DNA-binding, neuron-specific protein NeuN, which is present in most CNS and PNS neuronal cell types of all vertebrates tested. NeuN protein distributions are apparently restricted to neuronal nuclei, perikarya and some proximal neuronal processes in both fetal and adult brain although, some neurons fail to be recognized by NeuN at all ages: INL retinal cells, Cajal-Retzius cells, Purkinje cells, inferior olivary and dentate nucleus neurons, and sympathetic ganglion cells are examples (Mullen et al., 1992; Wolf et al., 1996). Immunohistochemically detectable NeuN protein first appears at developmental timepoints that correspond with the withdrawal of the neuron from the cell cycle and/or with the initiation of terminal differentiation of the neuron (Mullen et al., 1992). Immunoreactivity appears around E9.5 in the mouse neural tube and is extensive throughout the developing nervous system by E12.5. Strong nuclear staining suggests a nuclear regulatory protein function; however, no evidence currently exists as to whether the NeuN protein antigen has a function in the distal cytoplasm or whether it is merely synthesized there before being transported back into the nucleus. No difference between protein isolated from purified nuclei and whole brain extract on immunoblots has been found (Mullen et al., 1992).
ALT Names :
Neuron-Specific Nuclear Protein
Immunogen :
Purified cell nuclei from mouse brain
Specificity :
Vertebrate neuron-specific nuclear protein called NeuN (Neuronal Nuclei). MAB377B reacts with most neuronal cell types throughout the nervous system of mice including cerebellum, cerebral cortex, hippocampus, thalamus, spinal cord and neurons in the peripheral nervous system including dorsal root ganglia, sympathetic chain ganglia and enteric ganglia. The immunohistochemical staining is primarily in the nucleus of the neurons with lighter staining in the cytoplasm. The few cell types not reactive with MAB377B include Purkinje, mitral and photoreceptor cells. Developmentally, immunoreactivity is first observed shortly after neurons have become postmitotic, no staining has been observed in proliferative zones. The antibody is an excellent marker for neurons in primary cultures and in retinoic acid-stimulated P19 cells. It is also useful for identifying neurons in transplants.
Package Size :
500 µg
Uses :
Immunocytochemistry;Immunohistochemistry;Immunohistochemistry (Paraffin);Western Blotting
Storage :
Stable for 1 year at 2-8ºC from date of receipt.
company information
EMD Millipore
290 Concord Road
Billerica, Massachusetts 01821
bioscienceshelp@emdchemical.com
https://www.emdmillipore.com
888-854-3417
headquarters: United States
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

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