Lamaa A, Humbert J, Aguirrebengoa M, Cheng X, Nicolas E, Cote J, et al. Integrated analysis of H2A.Z isoforms function reveals a complex interplay in gene regulation. elife. 2020;9: pubmed publisher

Guo X, Kolpakov M, Hooshdaran B, Schappell W, Wang T, Eguchi S, et al. Cardiac Expression of Factor X Mediates Cardiac Hypertrophy and Fibrosis in Pressure Overload. JACC Basic Transl Sci. 2020;5:69-83 pubmed publisher

Sarker M, Lee J, Lee D, Chun K, Jun H. Attenuation of diabetic kidney injury in DPP4-deficient rats; role of GLP-1 on the suppression of AGE formation by inducing glyoxalase 1. Aging (Albany NY). 2020;12:593-610 pubmed publisher

Even A, Morelli G, Broix L, Scaramuzzino C, Turchetto S, Gladwyn Ng I, et al. ATAT1-enriched vesicles promote microtubule acetylation via axonal transport. Sci Adv. 2019;5:eaax2705 pubmed publisher

Harde E, Nicholson L, Furones Cuadrado B, Bissen D, Wigge S, Urban S, et al. EphrinB2 regulates VEGFR2 during dendritogenesis and hippocampal circuitry development. elife. 2019;8: pubmed publisher

Wessel S, Mohni K, Luzwick J, Dungrawala H, Cortez D. Functional Analysis of the Replication Fork Proteome Identifies BET Proteins as PCNA Regulators. Cell Rep. 2019;28:3497-3509.e4 pubmed publisher

Wolf Y, Bartok O, Patkar S, Eli G, Cohen S, Litchfield K, et al. UVB-Induced Tumor Heterogeneity Diminishes Immune Response in Melanoma. Cell. 2019;179:219-235.e21 pubmed publisher

Shao Q, Esseltine J, Huang T, Novielli Kuntz N, Ching J, SAMPSON J, et al. Connexin43 is Dispensable for Early Stage Human Mesenchymal Stem Cell Adipogenic Differentiation But is Protective against Cell Senescence. Biomolecules. 2019;9: pubmed publisher

Suh J, Romano D, Nitschke L, Herrick S, DiMarzio B, Dzhala V, et al. Loss of Ataxin-1 Potentiates Alzheimer's Pathogenesis by Elevating Cerebral BACE1 Transcription. Cell. 2019;178:1159-1175.e17 pubmed publisher

Gal H, Lysenko M, Stroganov S, Vadai E, Youssef S, Tzadikevitch Geffen K, et al. Molecular pathways of senescence regulate placental structure and function. EMBO J. 2019;38:e100849 pubmed publisher

Wu S, Fatkhutdinov N, Rosin L, Luppino J, Iwasaki O, Tanizawa H, et al. ARID1A spatially partitions interphase chromosomes. Sci Adv. 2019;5:eaaw5294 pubmed publisher

Kucab J, Zou X, Morganella S, Joel M, Nanda A, Nagy E, et al. A Compendium of Mutational Signatures of Environmental Agents. Cell. 2019;177:821-836.e16 pubmed publisher

Montalbán Loro R, Lozano Ureña A, Ito M, Krueger C, Reik W, Ferguson Smith A, et al. TET3 prevents terminal differentiation of adult NSCs by a non-catalytic action at Snrpn. Nat Commun. 2019;10:1726 pubmed publisher

Saito T, Kuma A, Sugiura Y, Ichimura Y, Obata M, Kitamura H, et al. Autophagy regulates lipid metabolism through selective turnover of NCoR1. Nat Commun. 2019;10:1567 pubmed publisher

Gong B, Kiyotani K, Sakata S, Nagano S, Kumehara S, Baba S, et al. Secreted PD-L1 variants mediate resistance to PD-L1 blockade therapy in non-small cell lung cancer. J Exp Med. 2019;: pubmed publisher

Georgouli M, Herraiz C, Crosas Molist E, Fanshawe B, Maiques O, Perdrix A, et al. Regional Activation of Myosin II in Cancer Cells Drives Tumor Progression via a Secretory Cross-Talk with the Immune Microenvironment. Cell. 2019;176:757-774.e23 pubmed publisher

Stojic A, Bojcevski J, Williams S, Bas Orth C, Nessler S, Linington C, et al. Preclinical stress originates in the rat optic nerve head during development of autoimmune optic neuritis. Glia. 2019;67:512-524 pubmed publisher

Fukushima M, Dasgupta D, Mauer A, Kakazu E, Nakao K, Malhi H. StAR-related lipid transfer domain 11 (STARD11)-mediated ceramide transport mediates extracellular vesicle biogenesis. J Biol Chem. 2018;293:15277-15289 pubmed publisher

Ziegler Waldkirch S, d Errico P, Sauer J, Erny D, Savanthrapadian S, Loreth D, et al. Seed-induced Aβ deposition is modulated by microglia under environmental enrichment in a mouse model of Alzheimer's disease. EMBO J. 2018;37:167-182 pubmed publisher

Liu S, Cheng C. Akt Signaling Is Sustained by a CD44 Splice Isoform-Mediated Positive Feedback Loop. Cancer Res. 2017;77:3791-3801 pubmed publisher

Menges S, Minakaki G, Schaefer P, Meixner H, Prots I, Schlötzer Schrehardt U, et al. Alpha-synuclein prevents the formation of spherical mitochondria and apoptosis under oxidative stress. Sci Rep. 2017;7:42942 pubmed publisher

Herring A, Messana A, Bara A, Hazelbaker D, Eggan K, Barrett L. Generation of a TLE1 homozygous knockout human embryonic stem cell line using CRISPR-Cas9. Stem Cell Res. 2016;17:430-432 pubmed publisher

Someya A, Ikegami T, Sakamoto K, Nagaoka I. Glucosamine Downregulates the IL-1?-Induced Expression of Proinflammatory Cytokine Genes in Human Synovial MH7A Cells by O-GlcNAc Modification-Dependent and -Independent Mechanisms. PLoS ONE. 2016;11:e0165158 pubmed publisher

Anderson D, Markway B, Bond D, McCarthy H, Johnstone B. Responses to altered oxygen tension are distinct between human stem cells of high and low chondrogenic capacity. Stem Cell Res Ther. 2016;7:154 pubmed

Cortes D, Robledo Arratia Y, Hernández Martinez R, Escobedo Ávila I, Bargas J, Velasco I. Transgenic GDNF Positively Influences Proliferation, Differentiation, Maturation and Survival of Motor Neurons Produced from Mouse Embryonic Stem Cells. Front Cell Neurosci. 2016;10:217 pubmed publisher

Bener G, J Félix A, Sánchez de Diego C, Pascual Fabregat I, Ciudad C, Noe V. Silencing of CD47 and SIRP? by Polypurine reverse Hoogsteen hairpins to promote MCF-7 breast cancer cells death by PMA-differentiated THP-1 cells. BMC Immunol. 2016;17:32 pubmed

Shamblott M, O Driscoll M, Gomez D, McGuire D. Neurogenin 3 is regulated by neurotrophic tyrosine kinase receptor type 2 (TRKB) signaling in the adult human exocrine pancreas. Cell Commun Signal. 2016;14:23 pubmed

Watanabe S, Simon V, Durham N, Kemp B, Machihara S, Kemal K, et al. The HIV-1 late domain-2 S40A polymorphism in antiretroviral (or ART)-exposed individuals influences protease inhibitor susceptibility. Retrovirology. 2016;13:64 pubmed publisher

Krawczyk K, Ekman M, Rippe C, Grossi M, Nilsson B, Albinsson S, et al. Assessing the contribution of thrombospondin-4 induction and ATF6? activation to endoplasmic reticulum expansion and phenotypic modulation in bladder outlet obstruction. Sci Rep. 2016;6:32449 pubmed publisher

Hong X, Liu W, Song R, Shah J, Feng X, Tsang C, et al. SOX9 is targeted for proteasomal degradation by the E3 ligase FBW7 in response to DNA damage. Nucleic Acids Res. 2016;44:8855-8869 pubmed

Padhan N, Nordling T, Sundstrom M, Akerud P, Birgisson H, Nygren P, et al. High sensitivity isoelectric focusing to establish a signaling biomarker for the diagnosis of human colorectal cancer. BMC Cancer. 2016;16:683 pubmed publisher

Kim M, Caplen N, Chakka S, Hernandez L, House C, Pongas G, et al. Identification of therapeutic targets applicable to clinical strategies in ovarian cancer. BMC Cancer. 2016;16:678 pubmed publisher

Fujita K, Motoki K, Tagawa K, Chen X, Hama H, Nakajima K, et al. HMGB1, a pathogenic molecule that induces neurite degeneration via TLR4-MARCKS, is a potential therapeutic target for Alzheimer's disease. Sci Rep. 2016;6:31895 pubmed publisher

Ruiz Palmero I, Ortiz Rodriguez A, Melcangi R, Caruso D, Garcia Segura L, Rune G, et al. Oestradiol synthesized by female neurons generates sex differences in neuritogenesis. Sci Rep. 2016;6:31891 pubmed publisher

Nakamichi R, Ito Y, Inui M, Onizuka N, Kayama T, Kataoka K, et al. Mohawk promotes the maintenance and regeneration of the outer annulus fibrosus of intervertebral discs. Nat Commun. 2016;7:12503 pubmed publisher

Gygli P, Chang J, Gokozan H, Catacutan F, Schmidt T, Kaya B, et al. Cyclin A2 promotes DNA repair in the brain during both development and aging. Aging (Albany NY). 2016;8:1540-70 pubmed publisher

Manassero G, Guglielmotto M, Zamfir R, Borghi R, Colombo L, Salmona M, et al. Beta-amyloid 1-42 monomers, but not oligomers, produce PHF-like conformation of Tau protein. Aging Cell. 2016;15:914-23 pubmed publisher

Sohn P, Tracy T, Son H, Zhou Y, Leite R, Miller B, et al. Acetylated tau destabilizes the cytoskeleton in the axon initial segment and is mislocalized to the somatodendritic compartment. Mol Neurodegener. 2016;11:47 pubmed publisher

Wang Y, Li Y, Hu G, Huang X, Rao H, Xiong X, et al. Nek2A phosphorylates and stabilizes SuFu: A new strategy of Gli2/Hedgehog signaling regulatory mechanism. Cell Signal. 2016;28:1304-13 pubmed publisher

Hey F, Giblett S, Forrest S, Herbert C, Pritchard C. Phosphorylations of Serines 21/9 in Glycogen Synthase Kinase 3α/β Are Not Required for Cell Lineage Commitment or WNT Signaling in the Normal Mouse Intestine. PLoS ONE. 2016;11:e0156877 pubmed publisher

Martin G, Chung S, Landrock D, Landrock K, Huang H, Dangott L, et al. FABP-1 gene ablation impacts brain endocannabinoid system in male mice. J Neurochem. 2016;138:407-22 pubmed publisher

Ding J, Nie M, Liu J, Hu X, Ma L, Deng Z, et al. Trbp Is Required for Differentiation of Myoblasts and Normal Regeneration of Skeletal Muscle. PLoS ONE. 2016;11:e0155349 pubmed publisher

Meinders M, Hoogenboezem M, Scheenstra M, De Cuyper I, Papadopoulos P, Nemeth T, et al. Repercussion of Megakaryocyte-Specific Gata1 Loss on Megakaryopoiesis and the Hematopoietic Precursor Compartment. PLoS ONE. 2016;11:e0154342 pubmed publisher

Chen P, Hsiao J, Sirois C, Chamberlain S. RBFOX1 and RBFOX2 are dispensable in iPSCs and iPSC-derived neurons and do not contribute to neural-specific paternal UBE3A silencing. Sci Rep. 2016;6:25368 pubmed publisher

Mao Y, Tamura T, Yuki Y, Abe D, Tamada Y, Imoto S, et al. The hnRNP-Htt axis regulates necrotic cell death induced by transcriptional repression through impaired RNA splicing. Cell Death Dis. 2016;7:e2207 pubmed publisher

Sun M, Asghar S, Zhang H. The polarity protein Par3 regulates APP trafficking and processing through the endocytic adaptor protein Numb. Neurobiol Dis. 2016;93:1-11 pubmed publisher

Valero T, Sturchler E, Jafferjee M, Rengo G, Magafa V, Cordopatis P, et al. Structure-activity relationship study of angiotensin II analogs in terms of β-arrestin-dependent signaling to aldosterone production. Pharmacol Res Perspect. 2016;4:e00226 pubmed publisher

Gómez López S, Martínez Silva A, Montiel T, Osorio Gómez D, Bermudez Rattoni F, Massieu L, et al. Neural ablation of the PARK10 candidate Plpp3 leads to dopaminergic transmission deficits without neurodegeneration. Sci Rep. 2016;6:24028 pubmed publisher

Waguia Kontchou C, Tzivelekidis T, Gentle I, Hacker G. Infection of epithelial cells with Chlamydia trachomatis inhibits TNF-induced apoptosis at the level of receptor internalization while leaving non-apoptotic TNF-signalling intact. Cell Microbiol. 2016;18:1583-1595 pubmed publisher

Pijut S, Corbett D, Wang Y, Li J, Charnigo R, Graf G. Effect of peripheral circadian dysfunction on metabolic disease in response to a diabetogenic diet. Am J Physiol Endocrinol Metab. 2016;310:E900-11 pubmed publisher

Yan X, Nykänen N, Brunello C, Haapasalo A, Hiltunen M, Uronen R, et al. FRMD4A-cytohesin signaling modulates the cellular release of tau. J Cell Sci. 2016;129:2003-15 pubmed publisher

Massengill M, Ashraf H, Chowdhury R, Chrzanowski S, Kar J, Warren S, et al. Acute heart failure with cardiomyocyte atrophy induced in adult mice by ablation of cardiac myosin light chain kinase. Cardiovasc Res. 2016;111:34-43 pubmed publisher

Prathipati P, Metreveli N, Nandi S, Tyagi S, Mishra P. Ablation of Matrix Metalloproteinase-9 Prevents Cardiomyocytes Contractile Dysfunction in Diabetics. Front Physiol. 2016;7:93 pubmed publisher

Antony A, Paillard M, Moffat C, Juskeviciute E, Correnti J, Bolon B, et al. MICU1 regulation of mitochondrial Ca(2+) uptake dictates survival and tissue regeneration. Nat Commun. 2016;7:10955 pubmed publisher

Johanns M, Lai Y, Hsu M, Jacobs R, Vertommen D, Van Sande J, et al. AMPK antagonizes hepatic glucagon-stimulated cyclic AMP signalling via phosphorylation-induced activation of cyclic nucleotide phosphodiesterase 4B. Nat Commun. 2016;7:10856 pubmed publisher

Carbognin E, Betto R, Soriano M, Smith A, Martello G. Stat3 promotes mitochondrial transcription and oxidative respiration during maintenance and induction of naive pluripotency. EMBO J. 2016;35:618-34 pubmed publisher

Hoa L, Kulaberoglu Y, Gundogdu R, Cook D, Mavis M, Gomez M, et al. The characterisation of LATS2 kinase regulation in Hippo-YAP signalling. Cell Signal. 2016;28:488-497 pubmed publisher

Puyang Z, Feng L, Chen H, Liang P, Troy J, Liu X. Retinal Ganglion Cell Loss is Delayed Following Optic Nerve Crush in NLRP3 Knockout Mice. Sci Rep. 2016;6:20998 pubmed publisher

Kim N, Kim M, Sung P, Bae Y, Shin E, Yoo J. Interferon-inducible protein SCOTIN interferes with HCV replication through the autolysosomal degradation of NS5A. Nat Commun. 2016;7:10631 pubmed publisher

Tanahashi H, Tian Q, Hara Y, Sakagami H, Endo S, Suzuki T. Polyhydramnios in Lrp4 knockout mice with bilateral kidney agenesis: Defects in the pathways of amniotic fluid clearance. Sci Rep. 2016;6:20241 pubmed publisher

Sharma A, Lyashchenko A, Lu L, Nasrabady S, Elmaleh M, Mendelsohn M, et al. ALS-associated mutant FUS induces selective motor neuron degeneration through toxic gain of function. Nat Commun. 2016;7:10465 pubmed publisher

Theodosiou M, Widmaier M, Böttcher R, Rognoni E, Veelders M, Bharadwaj M, et al. Kindlin-2 cooperates with talin to activate integrins and induces cell spreading by directly binding paxillin. elife. 2016;5:e10130 pubmed publisher

Abbey M, Hakim C, Anand R, Lafera J, Schambach A, Kispert A, et al. GTPase domain driven dimerization of SEPT7 is dispensable for the critical role of septins in fibroblast cytokinesis. Sci Rep. 2016;6:20007 pubmed publisher

Park W, Kim S, Kim Y, Park J. Bortezomib alleviates drug-induced liver injury by regulating CYP2E1 gene transcription. Int J Mol Med. 2016;37:613-22 pubmed publisher

Gingras J, Gawor M, Bernadzki K, Grady R, Hallock P, Glass D, et al. Α-Dystrobrevin-1 recruits Grb2 and α-catulin to organize neurotransmitter receptors at the neuromuscular junction. J Cell Sci. 2016;129:898-911 pubmed publisher

Priglinger C, Obermann J, Szober C, Merl Pham J, Ohmayer U, Behler J, et al. Epithelial-to-Mesenchymal Transition of RPE Cells In Vitro Confers Increased β1,6-N-Glycosylation and Increased Susceptibility to Galectin-3 Binding. PLoS ONE. 2016;11:e0146887 pubmed publisher

Kucab J, Zwart E, van Steeg H, Luijten M, Schmeiser H, Phillips D, et al. TP53 and lacZ mutagenesis induced by 3-nitrobenzanthrone in Xpa-deficient human TP53 knock-in mouse embryo fibroblasts. DNA Repair (Amst). 2016;39:21-33 pubmed publisher

Wang C, Che L, Hu J, Zhang S, Jiang L, Latte G, et al. Activated mutant forms of PIK3CA cooperate with RasV12 or c-Met to induce liver tumour formation in mice via AKT2/mTORC1 cascade. Liver Int. 2016;36:1176-86 pubmed publisher

Parvatiyar M, Marshall J, Nguyen R, Jordan M, Richardson V, Roos K, et al. Sarcospan Regulates Cardiac Isoproterenol Response and Prevents Duchenne Muscular Dystrophy-Associated Cardiomyopathy. J Am Heart Assoc. 2015;4: pubmed publisher

Xu J, El Refaey M, Xu L, Zhao L, Gao Y, Floyd K, et al. Genetic disruption of Ano5 in mice does not recapitulate human ANO5-deficient muscular dystrophy. Skelet Muscle. 2015;5:43 pubmed publisher

Gali Ramamoorthy T, Laverny G, Schlagowski A, Zoll J, Messaddeq N, Bornert J, et al. The transcriptional coregulator PGC-1β controls mitochondrial function and anti-oxidant defence in skeletal muscles. Nat Commun. 2015;6:10210 pubmed publisher

Ohashi A, Ohori M, Iwai K, Nambu T, Miyamoto M, Kawamoto T, et al. A Novel Time-Dependent CENP-E Inhibitor with Potent Antitumor Activity. PLoS ONE. 2015;10:e0144675 pubmed publisher

Isbel L, Srivastava R, Oey H, Spurling A, Daxinger L, Puthalakath H, et al. Trim33 Binds and Silences a Class of Young Endogenous Retroviruses in the Mouse Testis; a Novel Component of the Arms Race between Retrotransposons and the Host Genome. PLoS Genet. 2015;11:e1005693 pubmed publisher

Furlan S, Mosole S, Murgia M, Nagaraj N, Argenton F, Volpe P, et al. Calsequestrins in skeletal and cardiac muscle from adult Danio rerio. J Muscle Res Cell Motil. 2016;37:27-39 pubmed publisher

Chrisam M, Pirozzi M, Castagnaro S, Blaauw B, Polishchuck R, Cecconi F, et al. Reactivation of autophagy by spermidine ameliorates the myopathic defects of collagen VI-null mice. Autophagy. 2015;11:2142-52 pubmed publisher

Abshagen K, Senne M, Genz B, Thomas M, Vollmar B. Differential Effects of Axin2 Deficiency on the Fibrogenic and Regenerative Response in Livers of Bile Duct-Ligated Mice. Eur Surg Res. 2015;55:328-340 pubmed

Dale T, Clarke P, Esdar C, Waalboer D, Adeniji Popoola O, Ortiz Ruiz M, et al. A selective chemical probe for exploring the role of CDK8 and CDK19 in human disease. Nat Chem Biol. 2015;11:973-980 pubmed publisher

Hruska M, Henderson N, Xia N, Le Marchand S, Dalva M. Anchoring and synaptic stability of PSD-95 is driven by ephrin-B3. Nat Neurosci. 2015;18:1594-605 pubmed publisher

Kizuka Y, Nakano M, Kitazume S, Saito T, Saido T, Taniguchi N. Bisecting GlcNAc modification stabilizes BACE1 protein under oxidative stress conditions. Biochem J. 2016;473:21-30 pubmed publisher

Yao X, Carlson D, Sun Y, Ma L, Wolf S, Minei J, et al. Mitochondrial ROS Induces Cardiac Inflammation via a Pathway through mtDNA Damage in a Pneumonia-Related Sepsis Model. PLoS ONE. 2015;10:e0139416 pubmed publisher

Parsi S, Smith P, Goupil C, Dorval V, Hébert S. Preclinical Evaluation of miR-15/107 Family Members as Multifactorial Drug Targets for Alzheimer's Disease. Mol Ther Nucleic Acids. 2015;4:e256 pubmed publisher

Sirohi K, Kumari A, Radha V, Swarup G. A Glaucoma-Associated Variant of Optineurin, M98K, Activates Tbk1 to Enhance Autophagosome Formation and Retinal Cell Death Dependent on Ser177 Phosphorylation of Optineurin. PLoS ONE. 2015;10:e0138289 pubmed publisher

Lee K, Westin L, Kim J, Chang J, Oh Y, Amreen B, et al. Alteration by p11 of mGluR5 localization regulates depression-like behaviors. Mol Psychiatry. 2015;20:1546-56 pubmed publisher

Pellegrini C, Columbaro M, Capanni C, D Apice M, Cavallo C, Murdocca M, et al. All-trans retinoic acid and rapamycin normalize Hutchinson Gilford progeria fibroblast phenotype. Oncotarget. 2015;6:29914-28 pubmed publisher

Kelly J, Shao Q, Jagger D, Laird D. Cx30 exhibits unique characteristics including a long half-life when assembled into gap junctions. J Cell Sci. 2015;128:3947-60 pubmed publisher

Noritake K, Aki T, Funakoshi T, Unuma K, Uemura K. Direct Exposure to Ethanol Disrupts Junctional Cell-Cell Contact and Hippo-YAP Signaling in HL-1 Murine Atrial Cardiomyocytes. PLoS ONE. 2015;10:e0136952 pubmed publisher

Lin H, Ha K, Lu G, Fang X, Cheng R, Zuo Q, et al. Cdc14A and Cdc14B Redundantly Regulate DNA Double-Strand Break Repair. Mol Cell Biol. 2015;35:3657-68 pubmed publisher

Umansky K, Gruenbaum Cohen Y, Tsoory M, Feldmesser E, Goldenberg D, Brenner O, et al. Runx1 Transcription Factor Is Required for Myoblasts Proliferation during Muscle Regeneration. PLoS Genet. 2015;11:e1005457 pubmed publisher

Pasek J, Wang X, Colbran R. Differential CaMKII regulation by voltage-gated calcium channels in the striatum. Mol Cell Neurosci. 2015;68:234-43 pubmed publisher

Hagl S, Berressem D, Grewal R, Sus N, Frank J, Eckert G. Rice bran extract improves mitochondrial dysfunction in brains of aged NMRI mice. Nutr Neurosci. 2016;19:1-10 pubmed publisher

Ma Q, Hu Q, Xu R, Zhen X, Wang G. Protease Omi facilitates neurite outgrowth in mouse neuroblastoma N2a cells by cleaving transcription factor E2F1. Acta Pharmacol Sin. 2015;36:966-75 pubmed publisher

Kawalec M, Boratyńska Jasińska A, Beręsewicz M, Dymkowska D, Zabłocki K, Zabłocka B. Mitofusin 2 Deficiency Affects Energy Metabolism and Mitochondrial Biogenesis in MEF Cells. PLoS ONE. 2015;10:e0134162 pubmed publisher

Ragan C, Harding K, Lonstein J. Associations among within-litter differences in early mothering received and later emotional behaviors, mothering, and cortical tryptophan hydroxylase-2 expression in female laboratory rats. Horm Behav. 2016;77:62-71 pubmed publisher

Thomas A, Eijgelaar W, Daemen M, Newby A. Foam Cell Formation In Vivo Converts Macrophages to a Pro-Fibrotic Phenotype. PLoS ONE. 2015;10:e0128163 pubmed publisher

Santosa D, Castoldi M, Paluschinski M, Sommerfeld A, Häussinger D. Hyperosmotic stress activates the expression of members of the miR-15/107 family and induces downregulation of anti-apoptotic genes in rat liver. Sci Rep. 2015;5:12292 pubmed publisher

Perera R, Stoykova S, Nicolay B, Ross K, Fitamant J, Boukhali M, et al. Transcriptional control of autophagy-lysosome function drives pancreatic cancer metabolism. Nature. 2015;524:361-5 pubmed publisher

Beckman D, Santos L, Americo T, Ledo J, de Mello F, Linden R. Prion Protein Modulates Monoaminergic Systems and Depressive-like Behavior in Mice. J Biol Chem. 2015;290:20488-98 pubmed publisher

Ohashi A, Ohori M, Iwai K, Nakayama Y, Nambu T, Morishita D, et al. Aneuploidy generates proteotoxic stress and DNA damage concurrently with p53-mediated post-mitotic apoptosis in SAC-impaired cells. Nat Commun. 2015;6:7668 pubmed publisher

Duan H, Zhang Y, Zhang X, Xu H, Shu J, Xu S. Antinociceptive roles of galanin receptor 1 in nucleus accumbens of rats in a model of neuropathic pain. J Neurosci Res. 2015;93:1542-51 pubmed publisher

Yang L, Li Y, Bhattacharya A, Zhang Y. Inhibition of ERBB2-overexpressing Tumors by Recombinant Human Prolidase and Its Enzymatically Inactive Mutant. EBioMedicine. 2015;2:396-405 pubmed

Nishioka M, Venkatesan N, Dessalle K, Mogas A, Kyoh S, Lin T, et al. Fibroblast-epithelial cell interactions drive epithelial-mesenchymal transition differently in cells from normal and COPD patients. Respir Res. 2015;16:72 pubmed publisher

Dille S, Kleinschnitz E, Kontchou C, Nölke T, Häcker G. In contrast to Chlamydia trachomatis, Waddlia chondrophila grows in human cells without inhibiting apoptosis, fragmenting the Golgi apparatus, or diverting post-Golgi sphingomyelin transport. Infect Immun. 2015;83:3268-80 pubmed publisher

Ding J, Chen J, Wang Y, Kataoka M, Ma L, Zhou P, et al. Trbp regulates heart function through microRNA-mediated Sox6 repression. Nat Genet. 2015;47:776-83 pubmed publisher

Chuprin A, Avin A, Goldfarb Y, Herzig Y, Levi B, Jacob A, et al. The deacetylase Sirt1 is an essential regulator of Aire-mediated induction of central immunological tolerance. Nat Immunol. 2015;16:737-45 pubmed publisher

Petrov D, Pedrós I, Artiach G, Sureda F, Barroso E, Pallas M, et al. High-fat diet-induced deregulation of hippocampal insulin signaling and mitochondrial homeostasis deficiences contribute to Alzheimer disease pathology in rodents. Biochim Biophys Acta. 2015;1852:1687-99 pubmed publisher

Krais A, Speksnijder E, Melis J, Indra R, Moserova M, Godschalk R, et al. The impact of p53 on DNA damage and metabolic activation of the environmental carcinogen benzo[a]pyrene: effects in Trp53(+/+), Trp53(+/-) and Trp53(-/-) mice. Arch Toxicol. 2016;90:839-51 pubmed publisher

Bozickovic O, Hoang T, Fenne I, Helland T, Skartveit L, Ouchida M, et al. Cyclin C interacts with steroid receptor coactivator 2 and upregulates cell cycle genes in MCF-7 cells. Biochim Biophys Acta. 2015;1853:2383-91 pubmed publisher

De Zio D, Molinari F, Rizza S, Gatta L, Ciotti M, Salvatore A, et al. Apaf1-deficient cortical neurons exhibit defects in axonal outgrowth. Cell Mol Life Sci. 2015;72:4173-91 pubmed publisher

Heinen A, Beyer F, Tzekova N, Hartung H, Küry P. Fingolimod induces the transition to a nerve regeneration promoting Schwann cell phenotype. Exp Neurol. 2015;271:25-35 pubmed publisher

Bernard L, Zhang H. MARK/Par1 Kinase Is Activated Downstream of NMDA Receptors through a PKA-Dependent Mechanism. PLoS ONE. 2015;10:e0124816 pubmed publisher

Chimura T, Launey T, Yoshida N. Calpain-Mediated Degradation of Drebrin by Excitotoxicity In vitro and In vivo. PLoS ONE. 2015;10:e0125119 pubmed publisher

Chung J, Bauer D, Ghamari A, Nizzi C, Deck K, Kingsley P, et al. The mTORC1/4E-BP pathway coordinates hemoglobin production with L-leucine availability. Sci Signal. 2015;8:ra34 pubmed publisher

Fei F, Joo E, Tarighat S, Schiffer I, Paz H, Fabbri M, et al. B-cell precursor acute lymphoblastic leukemia and stromal cells communicate through Galectin-3. Oncotarget. 2015;6:11378-94 pubmed

Chen M, Gan X, Deng L, Hotta H. The NS5A protein of hepatitis C virus transcriptionally upregulates the AGR3 gene expression. Kobe J Med Sci. 2015;61:E27-35 pubmed

Gillory L, Stewart J, Megison M, Waters A, Beierle E. Focal adhesion kinase and p53 synergistically decrease neuroblastoma cell survival. J Surg Res. 2015;196:339-49 pubmed publisher

Lavoz C, Alique M, Rodrígues Díez R, Pato J, Keri G, Mezzano S, et al. Gremlin regulates renal inflammation via the vascular endothelial growth factor receptor 2 pathway. J Pathol. 2015;236:407-20 pubmed publisher

Nakamura K, Nakabayashi K, Htet Aung K, Aizawa K, Hori N, Yamauchi J, et al. DNA methyltransferase inhibitor zebularine induces human cholangiocarcinoma cell death through alteration of DNA methylation status. PLoS ONE. 2015;10:e0120545 pubmed publisher

Ueda K, Yoshimura K, Yamashita O, Harada T, Morikage N, Hamano K. Possible dual role of decorin in abdominal aortic aneurysm. PLoS ONE. 2015;10:e0120689 pubmed publisher

Kim S, Wen W, Prowse P, Hamilton D. Regulation of matrix remodelling phenotype in gingival fibroblasts by substratum topography. J Cell Mol Med. 2015;19:1183-96 pubmed publisher

Gómez Sánchez R, Pizarro Estrella E, Yakhine Diop S, Rodríguez Arribas M, Bravo San Pedro J, Fuentes J, et al. Routine Western blot to check autophagic flux: cautions and recommendations. Anal Biochem. 2015;477:13-20 pubmed publisher

Lim J, Lachenmayer M, Wu S, Liu W, Kundu M, Wang R, et al. Proteotoxic stress induces phosphorylation of p62/SQSTM1 by ULK1 to regulate selective autophagic clearance of protein aggregates. PLoS Genet. 2015;11:e1004987 pubmed publisher

van de Ven R, Tenhagen M, Meuleman W, van Riel J, Schackmann R, Derksen P. Nuclear p120-catenin regulates the anoikis resistance of mouse lobular breast cancer cells through Kaiso-dependent Wnt11 expression. Dis Model Mech. 2015;8:373-84 pubmed publisher

Heston J, White S. Behavior-linked FoxP2 regulation enables zebra finch vocal learning. J Neurosci. 2015;35:2885-94 pubmed publisher

Bitler B, Aird K, Garipov A, Li H, Amatangelo M, Kossenkov A, et al. Synthetic lethality by targeting EZH2 methyltransferase activity in ARID1A-mutated cancers. Nat Med. 2015;21:231-8 pubmed publisher

Bertaux Skeirik N, Feng R, Schumacher M, Li J, Mahé M, Engevik A, et al. CD44 plays a functional role in Helicobacter pylori-induced epithelial cell proliferation. PLoS Pathog. 2015;11:e1004663 pubmed publisher

Stickles X, Marchion D, Bicaku E, Al Sawah E, Abbasi F, Xiong Y, et al. BAD-mediated apoptotic pathway is associated with human cancer development. Int J Mol Med. 2015;35:1081-7 pubmed publisher

Lewinska A, Wnuk M, Grabowska W, Zabek T, Semik E, Sikora E, et al. Curcumin induces oxidation-dependent cell cycle arrest mediated by SIRT7 inhibition of rDNA transcription in human aortic smooth muscle cells. Toxicol Lett. 2015;233:227-38 pubmed publisher

Yan Y, Tsukamoto O, Nakano A, Kato H, Kioka H, Ito N, et al. Augmented AMPK activity inhibits cell migration by phosphorylating the novel substrate Pdlim5. Nat Commun. 2015;6:6137 pubmed publisher

Jiang X, Ma T, Zhang Y, Zhang H, Yin S, Zheng W, et al. Specific deletion of Cdh2 in Sertoli cells leads to altered meiotic progression and subfertility of mice. Biol Reprod. 2015;92:79 pubmed publisher

Lee E, Kim S, Cho K. Reconstituted High-Density Lipoprotein Containing Human Growth Hormone-1 Shows Potent Tissue Regeneration Activity with Enhancement of Anti-Oxidant and Anti-Atherosclerotic Activities. Rejuvenation Res. 2015;18:245-56 pubmed publisher

Han X, Chen M, Hong T, Zhu L, He D, Feng J, et al. Lentivirus-mediated RNAi knockdown of the gap junction protein, Cx43, attenuates the development of vascular restenosis following balloon injury. Int J Mol Med. 2015;35:885-92 pubmed publisher

Garcia Alvarez G, Lu B, Yap K, Wong L, Thevathasan J, Lim L, et al. STIM2 regulates PKA-dependent phosphorylation and trafficking of AMPARs. Mol Biol Cell. 2015;26:1141-59 pubmed publisher

Veeranki S, Tyagi S. Mechanisms of hyperhomocysteinemia induced skeletal muscle myopathy after ischemia in the CBS-/+ mouse model. Int J Mol Sci. 2015;16:1252-65 pubmed publisher

Vosper J, Masuccio A, Kullmann M, Ploner C, Geley S, Hengst L. Statin-induced depletion of geranylgeranyl pyrophosphate inhibits cell proliferation by a novel pathway of Skp2 degradation. Oncotarget. 2015;6:2889-902 pubmed

Lazorthes S, Vallot C, Briois S, Aguirrebengoa M, Thuret J, St Laurent G, et al. A vlincRNA participates in senescence maintenance by relieving H2AZ-mediated repression at the INK4 locus. Nat Commun. 2015;6:5971 pubmed publisher

Shibata H, Kanadome T, Sugiura H, Yokoyama T, Yamamuro M, Moss S, et al. A new role for annexin A11 in the early secretory pathway via stabilizing Sec31A protein at the endoplasmic reticulum exit sites (ERES). J Biol Chem. 2015;290:4981-93 pubmed publisher

Singh K, Lovren F, Pan Y, Quan A, Ramadan A, Matkar P, et al. The essential autophagy gene ATG7 modulates organ fibrosis via regulation of endothelial-to-mesenchymal transition. J Biol Chem. 2015;290:2547-59 pubmed publisher

Ito H, Fujita K, Tagawa K, Chen X, Homma H, Sasabe T, et al. HMGB1 facilitates repair of mitochondrial DNA damage and extends the lifespan of mutant ataxin-1 knock-in mice. EMBO Mol Med. 2015;7:78-101 pubmed publisher

Bang B, Kim S, Yagita H, Croft M, Kang Y. Inhibition of 4-1BBL-regulated TLR response in macrophages ameliorates endotoxin-induced sepsis in mice. Eur J Immunol. 2015;45:886-92 pubmed publisher

Shen W, Li H, Chen G, Chern Y, Tu P. Mutations in the ubiquitin-binding domain of OPTN/optineurin interfere with autophagy-mediated degradation of misfolded proteins by a dominant-negative mechanism. Autophagy. 2015;11:685-700 pubmed publisher

Wallingford M, Filkins R, Adams D, Walentuk M, Salicioni A, Visconti P, et al. Identification of a novel isoform of the leukemia-associated MLLT1 (ENL/LTG19) protein. Gene Expr Patterns. 2015;17:11-5 pubmed publisher

Langone F, Cannata S, Fuoco C, Lettieri Barbato D, Testa S, Nardozza A, et al. Metformin protects skeletal muscle from cardiotoxin induced degeneration. PLoS ONE. 2014;9:e114018 pubmed publisher

Liu Y, Atkinson R, Fernandez Martos C, Kirkcaldie M, Cui H, Vickers J, et al. Changes in TDP-43 expression in development, aging, and in the neurofilament light protein knockout mouse. Neurobiol Aging. 2015;36:1151-9 pubmed publisher

Fahl S, Harris B, Coffey F, Wiest D. Rpl22 Loss Impairs the Development of B Lymphocytes by Activating a p53-Dependent Checkpoint. J Immunol. 2015;194:200-9 pubmed

Holloway A, Simmonds M, Azad A, Fox J, Storey A. Resistance to UV-induced apoptosis by β-HPV5 E6 involves targeting of activated BAK for proteolysis by recruitment of the HERC1 ubiquitin ligase. Int J Cancer. 2015;136:2831-43 pubmed publisher

Jiang X, Zhang H, Yin S, Zhang Y, Yang W, Zheng W, et al. Specific deficiency of Plzf paralog, Zbtb20, in Sertoli cells does not affect spermatogenesis and fertility in mice. Sci Rep. 2014;4:7062 pubmed publisher

Stukas S, Robert J, Lee M, Kulic I, Carr M, Tourigny K, et al. Intravenously injected human apolipoprotein A-I rapidly enters the central nervous system via the choroid plexus. J Am Heart Assoc. 2014;3:e001156 pubmed publisher

Englert N, Luo G, Goldstein J, Surapureddi S. Epigenetic modification of histone 3 lysine 27: mediator subunit MED25 is required for the dissociation of polycomb repressive complex 2 from the promoter of cytochrome P450 2C9. J Biol Chem. 2015;290:2264-78 pubmed publisher

Chiang D, Kongchan N, Beavers D, Alsina K, Voigt N, Neilson J, et al. Loss of microRNA-106b-25 cluster promotes atrial fibrillation by enhancing ryanodine receptor type-2 expression and calcium release. Circ Arrhythm Electrophysiol. 2014;7:1214-22 pubmed publisher

Pettinato G, Vanden Berg Foels W, Zhang N, Wen X. ROCK inhibitor is not required for embryoid body formation from singularized human embryonic stem cells. PLoS ONE. 2014;9:e100742 pubmed publisher

Matsuo R, Morihara H, Mohri T, Murasawa S, Takewaki K, Nakayama H, et al. The inhibition of N-glycosylation of glycoprotein 130 molecule abolishes STAT3 activation by IL-6 family cytokines in cultured cardiac myocytes. PLoS ONE. 2014;9:e111097 pubmed publisher

Miyamoto Y, Mauer A, Kumar S, Mott J, Malhi H. Mmu-miR-615-3p regulates lipoapoptosis by inhibiting C/EBP homologous protein. PLoS ONE. 2014;9:e109637 pubmed publisher

Orchard Webb D, Lee T, Cook G, Blair G. CUB domain containing protein 1 (CDCP1) modulates adhesion and motility in colon cancer cells. BMC Cancer. 2014;14:754 pubmed publisher

Martin G, Atshaves B, Landrock K, Landrock D, Storey S, Howles P, et al. Ablating L-FABP in SCP-2/SCP-x null mice impairs bile acid metabolism and biliary HDL-cholesterol secretion. Am J Physiol Gastrointest Liver Physiol. 2014;307:G1130-43 pubmed publisher

Kannike K, Sepp M, Zuccato C, Cattaneo E, Timmusk T. Forkhead transcription factor FOXO3a levels are increased in Huntington disease because of overactivated positive autofeedback loop. J Biol Chem. 2014;289:32845-57 pubmed publisher

Huang S, Lee C, Wang H, Chang Y, Lin C, Chen C, et al. 6-Dehydrogingerdione restrains lipopolysaccharide-induced inflammatory responses in RAW 264.7 macrophages. J Agric Food Chem. 2014;62:9171-9 pubmed publisher

Radonjić N, Memi F, Ortega J, Glidden N, Zhan H, Zecevic N. The Role of Sonic Hedgehog in the Specification of Human Cortical Progenitors In Vitro. Cereb Cortex. 2016;26:131-43 pubmed publisher

Zhong W, Hutchinson T, Chebolu S, Darmani N. Serotonin 5-HT3 receptor-mediated vomiting occurs via the activation of Ca2+/CaMKII-dependent ERK1/2 signaling in the least shrew (Cryptotis parva). PLoS ONE. 2014;9:e104718 pubmed publisher

Xu R, Hu Q, Ma Q, Liu C, Wang G. The protease Omi regulates mitochondrial biogenesis through the GSK3β/PGC-1α pathway. Cell Death Dis. 2014;5:e1373 pubmed publisher

Balaz M, Ukropcova B, Kurdiova T, Gajdosechova L, Vlcek M, Janakova Z, et al. Adipokine zinc-?2-glycoprotein regulated by growth hormone and linked to insulin sensitivity. Obesity (Silver Spring). 2015;23:322-8 pubmed publisher

Matsuda M, Suzuki R, Kataoka C, Watashi K, Aizaki H, Kato N, et al. Alternative endocytosis pathway for productive entry of hepatitis C virus. J Gen Virol. 2014;95:2658-67 pubmed publisher

Zhang H, Petit G, Gaughwin P, Hansen C, Ranganathan S, Zuo X, et al. NGF rescues hippocampal cholinergic neuronal markers, restores neurogenesis, and improves the spatial working memory in a mouse model of Huntington's Disease. J Huntingtons Dis. 2013;2:69-82 pubmed publisher

Resch U, Cuapio A, Sturtzel C, Hofer E, de Martin R, Holper Schichl Y. Polyubiquitinated tristetraprolin protects from TNF-induced, caspase-mediated apoptosis. J Biol Chem. 2014;289:25088-100 pubmed publisher

Althoff K, Lindner S, Odersky A, Mestdagh P, Beckers A, Karczewski S, et al. miR-542-3p exerts tumor suppressive functions in neuroblastoma by downregulating Survivin. Int J Cancer. 2015;136:1308-20 pubmed publisher

Ettle B, Reiprich S, Deusser J, Schlachetzki J, Xiang W, Prots I, et al. Intracellular alpha-synuclein affects early maturation of primary oligodendrocyte progenitor cells. Mol Cell Neurosci. 2014;62:68-78 pubmed publisher

Subramaniam S, Vergnes L, Franich N, Reue K, Chesselet M. Region specific mitochondrial impairment in mice with widespread overexpression of alpha-synuclein. Neurobiol Dis. 2014;70:204-13 pubmed publisher

Maric M, Haugo A, Dauer W, Johnson D, Roller R. Nuclear envelope breakdown induced by herpes simplex virus type 1 involves the activity of viral fusion proteins. Virology. 2014;460-461:128-37 pubmed publisher

Sojka S, Amin N, Gibbs D, Christine K, Charpentier M, Conlon F. Congenital heart disease protein 5 associates with CASZ1 to maintain myocardial tissue integrity. Development. 2014;141:3040-9 pubmed publisher

Stewart M, Plante I, Bechberger J, Naus C, Laird D. Mammary gland specific knockdown of the physiological surge in Cx26 during lactation retains normal mammary gland development and function. PLoS ONE. 2014;9:e101546 pubmed publisher

Stukas S, Freeman L, Lee M, Wilkinson A, Ossoli A, Vaisman B, et al. LCAT deficiency does not impair amyloid metabolism in APP/PS1 mice. J Lipid Res. 2014;55:1721-9 pubmed publisher

Pedr s I, Petrov D, Allgaier M, Sureda F, Barroso E, Beas Zarate C, et al. Early alterations in energy metabolism in the hippocampus of APPswe/PS1dE9 mouse model of Alzheimer's disease. Biochim Biophys Acta. 2014;1842:1556-66 pubmed publisher

Xiong X, Wang Y, Liu C, Lu Q, Liu T, Chen G, et al. Heat shock protein 90? stabilizes focal adhesion kinase and enhances cell migration and invasion in breast cancer cells. Exp Cell Res. 2014;326:78-89 pubmed publisher

Zeng L, Holly J, Perks C. Effects of physiological levels of the green tea extract epigallocatechin-3-gallate on breast cancer cells. Front Endocrinol (Lausanne). 2014;5:61 pubmed publisher

Assirelli E, Pulsatelli L, Dolzani P, Platano D, Olivotto E, Filardo G, et al. Human osteoarthritic cartilage shows reduced in vivo expression of IL-4, a chondroprotective cytokine that differentially modulates IL-1?-stimulated production of chemokines and matrix-degrading enzymes in vitro. PLoS ONE. 2014;9:e96925 pubmed publisher

Miyazawa M, Tsuji Y. Evidence for a novel antioxidant function and isoform-specific regulation of the human p66Shc gene. Mol Biol Cell. 2014;25:2116-27 pubmed publisher

Watanabe M, Funakoshi T, Unuma K, Aki T, Uemura K. Activation of the ubiquitin-proteasome system against arsenic trioxide cardiotoxicity involves ubiquitin ligase Parkin for mitochondrial homeostasis. Toxicology. 2014;322:43-50 pubmed publisher

Losa D, Köhler T, Bellec J, Dudez T, Crespin S, Bacchetta M, et al. Pseudomonas aeruginosa-induced apoptosis in airway epithelial cells is mediated by gap junctional communication in a JNK-dependent manner. J Immunol. 2014;192:4804-12 pubmed publisher

Okuda H, Tatsumi K, Horii Hayashi N, Morita S, Okuda Yamamoto A, Imaizumi K, et al. OASIS regulates chondroitin 6-O-sulfotransferase 1 gene transcription in the injured adult mouse cerebral cortex. J Neurochem. 2014;130:612-25 pubmed publisher

Wang J, Huang F, Kuo M, Wang Z, Tseng T, Chang L, et al. Inhibition of cancer cell migration and invasion through suppressing the Wnt1-mediating signal pathway by G-quadruplex structure stabilizers. J Biol Chem. 2014;289:14612-23 pubmed publisher

Perdomini M, Belbellaa B, Monassier L, Reutenauer L, Messaddeq N, Cartier N, et al. Prevention and reversal of severe mitochondrial cardiomyopathy by gene therapy in a mouse model of Friedreich's ataxia. Nat Med. 2014;20:542-7 pubmed publisher

Swärd K, Albinsson S, Rippe C. Arterial dysfunction but maintained systemic blood pressure in cavin-1-deficient mice. PLoS ONE. 2014;9:e92428 pubmed publisher

Schroder W, Major L, Le T, Gardner J, Sweet M, Janciauskiene S, et al. Tumor cell-expressed SerpinB2 is present on microparticles and inhibits metastasis. Cancer Med. 2014;3:500-13 pubmed publisher

Haas M, Onstead Haas L, Naem E, Wong N, Mooradian A. Induction of apolipoprotein A-I gene expression by black seed (Nigella sativa) extracts. Pharm Biol. 2014;52:1119-27 pubmed publisher

Sambrotta M, Strautnieks S, Papouli E, Rushton P, Clark B, Parry D, et al. Mutations in TJP2 cause progressive cholestatic liver disease. Nat Genet. 2014;46:326-8 pubmed publisher

Wakai M, Abe S, Kazuki Y, Oshimura M, Ishikawa F. A human artificial chromosome recapitulates the metabolism of native telomeres in mammalian cells. PLoS ONE. 2014;9:e88530 pubmed publisher

Chen Q, Xu R, Zeng C, Lu Q, Huang D, Shi C, et al. Down-regulation of Gli transcription factor leads to the inhibition of migration and invasion of ovarian cancer cells via integrin ?4-mediated FAK signaling. PLoS ONE. 2014;9:e88386 pubmed publisher

Alkam T, Chebolu S, Darmani N. Cyclophosphamide causes activation of protein kinase A (PKA) in the brainstem of vomiting least shrews (Cryptotis parva). Eur J Pharmacol. 2014;722:156-64 pubmed

Yoshida T, Yamashita M, Horimai C, Hayashi M. Deletion of Krüppel-like factor 4 in endothelial and hematopoietic cells enhances neointimal formation following vascular injury. J Am Heart Assoc. 2014;3:e000622 pubmed publisher

Kirsch S, Schrezenmeier E, Klare S, Zaade D, Seidel K, Schmitz J, et al. The (pro)renin receptor mediates constitutive PLZF-independent pro-proliferative effects which are inhibited by bafilomycin but not genistein. Int J Mol Med. 2014;33:795-808 pubmed publisher

Belanger F, Rajotte V, Drobetsky E. A majority of human melanoma cell lines exhibits an S phase-specific defect in excision of UV-induced DNA photoproducts. PLoS ONE. 2014;9:e85294 pubmed publisher

Schweikl H, Petzel C, Bolay C, Hiller K, Buchalla W, Krifka S. 2-Hydroxyethyl methacrylate-induced apoptosis through the ATM- and p53-dependent intrinsic mitochondrial pathway. Biomaterials. 2014;35:2890-904 pubmed publisher

Toko H, Hariharan N, Konstandin M, Ormachea L, McGregor M, Gude N, et al. Differential regulation of cellular senescence and differentiation by prolyl isomerase Pin1 in cardiac progenitor cells. J Biol Chem. 2014;289:5348-56 pubmed publisher

Ekman M, Bhattachariya A, Dahan D, Uvelius B, Albinsson S, Swärd K. Mir-29 repression in bladder outlet obstruction contributes to matrix remodeling and altered stiffness. PLoS ONE. 2013;8:e82308 pubmed publisher

Brot S, Auger C, Bentata R, Rogemond V, Ménigoz S, Chounlamountri N, et al. Collapsin response mediator protein 5 (CRMP5) induces mitophagy, thereby regulating mitochondrion numbers in dendrites. J Biol Chem. 2014;289:2261-76 pubmed publisher

Swärd K, Sadegh M, Mori M, Erjefalt J, Rippe C. Elevated pulmonary arterial pressure and altered expression of Ddah1 and Arg1 in mice lacking cavin-1/PTRF. Physiol Rep. 2013;1:e00008 pubmed publisher

Nikolaenko L, Jia Y, Wang C, Diaz Arjonilla M, Yee J, French S, et al. Testosterone replacement ameliorates nonalcoholic fatty liver disease in castrated male rats. Endocrinology. 2014;155:417-28 pubmed publisher

Judson M, Sosa Pagán J, Del Cid W, Han J, Philpot B. Allelic specificity of Ube3a expression in the mouse brain during postnatal development. J Comp Neurol. 2014;522:1874-96 pubmed publisher

Wei P, Zhang L, Nethi S, Barui A, Lin J, Zhou W, et al. Accelerating the clearance of mutant huntingtin protein aggregates through autophagy induction by europium hydroxide nanorods. Biomaterials. 2014;35:899-907 pubmed publisher

Haas M, Onstead Haas L, Naem E, Arnold A, Rohrbaugh N, Flowers M, et al. The effect of black seed (Nigella sativa) extract on FOXO3 expression in HepG2 cells. Phytother Res. 2014;28:873-9 pubmed publisher

Clark S, Rainville J, Zhao X, Katzenellenbogen B, Pfaff D, Vasudevan N. Estrogen receptor-mediated transcription involves the activation of multiple kinase pathways in neuroblastoma cells. J Steroid Biochem Mol Biol. 2014;139:45-53 pubmed publisher

Mack H, Munger K. The LKB1 tumor suppressor differentially affects anchorage independent growth of HPV positive cervical cancer cell lines. Virology. 2013;446:9-16 pubmed publisher

Parseghian S, Onstead Haas L, Wong N, Mooradian A, Haas M. Inhibition of apolipoprotein A-I expression by TNF-alpha in HepG2 cells: requirement for c-jun. J Cell Biochem. 2014;115:253-60 pubmed publisher

Ahmed S, Prigent S. A nuclear export signal and oxidative stress regulate ShcD subcellular localisation: a potential role for ShcD in the nucleus. Cell Signal. 2014;26:32-40 pubmed publisher

Gupte M, Tuck A, Sharma V, Williams K. Major differences between tumor and normal human cell fates after exposure to chemotherapeutic monofunctional alkylator. PLoS ONE. 2013;8:e74071 pubmed publisher

Reese C, Dyer S, Perry B, Bonner M, Oates J, Hofbauer A, et al. Differential regulation of cell functions by CSD peptide subdomains. Respir Res. 2013;14:90 pubmed publisher

Mazard T, Causse A, Simony J, Leconet W, Vezzio Vié N, Torro A, et al. Sorafenib overcomes irinotecan resistance in colorectal cancer by inhibiting the ABCG2 drug-efflux pump. Mol Cancer Ther. 2013;12:2121-34 pubmed publisher

Okuda J, Niizuma S, Shioi T, Kato T, Inuzuka Y, Kawashima T, et al. Persistent overexpression of phosphoglycerate mutase, a glycolytic enzyme, modifies energy metabolism and reduces stress resistance of heart in mice. PLoS ONE. 2013;8:e72173 pubmed publisher

Chang C, Chen C, Wu M, Chen Y, Chen C, Sheu S, et al. Active Component of Antrodia cinnamomea Mycelia Targeting Head and Neck Cancer Initiating Cells through Exaggerated Autophagic Cell Death. Evid Based Complement Alternat Med. 2013;2013:946451 pubmed publisher

Gobbi G, Mirandola P, Carubbi C, Masselli E, Sykes S, Ferraro F, et al. Proplatelet generation in the mouse requires PKC?-dependent RhoA inhibition. Blood. 2013;122:1305-11 pubmed publisher

Condro M, White S. Distribution of language-related Cntnap2 protein in neural circuits critical for vocal learning. J Comp Neurol. 2014;522:169-85 pubmed publisher

Jacobi C, Rudigier L, Scholz H, Kirschner K. Transcriptional regulation by the Wilms tumor protein, Wt1, suggests a role of the metalloproteinase Adamts16 in murine genitourinary development. J Biol Chem. 2013;288:18811-24 pubmed publisher

LaFauci G, Adayev T, Kascsak R, Kascsak R, Nolin S, Mehta P, et al. Fragile X screening by quantification of FMRP in dried blood spots by a Luminex immunoassay. J Mol Diagn. 2013;15:508-17 pubmed publisher

Licandro G, Ling Khor H, Beretta O, Lai J, Derks H, Laudisi F, et al. The NLRP3 inflammasome affects DNA damage responses after oxidative and genotoxic stress in dendritic cells. Eur J Immunol. 2013;43:2126-37 pubmed publisher

Pendleton J, Shamblott M, Gary D, Belegu V, Hurtado A, Malone M, et al. Chondroitin sulfate proteoglycans inhibit oligodendrocyte myelination through PTP?. Exp Neurol. 2013;247:113-21 pubmed publisher

Panguluri S, Tur J, Fukumoto J, Deng W, Sneed K, Kolliputi N, et al. Hyperoxia-induced hypertrophy and ion channel remodeling in left ventricle. Am J Physiol Heart Circ Physiol. 2013;304:H1651-61 pubmed publisher

Rhee S, Guerrero Zayas M, Wallingford M, Ortíz Pineda P, Mager J, Tremblay K. Visceral endoderm expression of Yin-Yang1 (YY1) is required for VEGFA maintenance and yolk sac development. PLoS ONE. 2013;8:e58828 pubmed publisher

Valente A, Yoshida T, Clark R, Delafontaine P, Siebenlist U, Chandrasekar B. Advanced oxidation protein products induce cardiomyocyte death via Nox2/Rac1/superoxide-dependent TRAF3IP2/JNK signaling. Free Radic Biol Med. 2013;60:125-35 pubmed publisher

Mehmood T, Schneider A, Pannetier S, Hanauer A. Rsk2 Knockdown in PC12 Cells Results in Sp1 Dependent Increased Expression of the Gria2 Gene, Encoding the AMPA Receptor Subunit GluR2. Int J Mol Sci. 2013;14:3358-75 pubmed publisher

Sirohi K, Chalasani M, Sudhakar C, Kumari A, Radha V, Swarup G. M98K-OPTN induces transferrin receptor degradation and RAB12-mediated autophagic death in retinal ganglion cells. Autophagy. 2013;9:510-27 pubmed publisher

Nakamura K, Aizawa K, Nakabayashi K, Kato N, Yamauchi J, Hata K, et al. DNA methyltransferase inhibitor zebularine inhibits human hepatic carcinoma cells proliferation and induces apoptosis. PLoS ONE. 2013;8:e54036 pubmed publisher

Liao K, Sikkema D, Wang C, Lee T. Development of an enzymatic assay for the detection of neutralizing antibodies against therapeutic angiotensin-converting enzyme 2 (ACE2). J Immunol Methods. 2013;389:52-60 pubmed publisher

Ballarino M, Jobert L, Dembele D, de la Grange P, Auboeuf D, Tora L. TAF15 is important for cellular proliferation and regulates the expression of a subset of cell cycle genes through miRNAs. Oncogene. 2013;32:4646-55 pubmed publisher

Tripathy D, Sanchez A, Yin X, Martinez J, Grammas P. Age-related decrease in cerebrovascular-derived neuroprotective proteins: effect of acetaminophen. Microvasc Res. 2012;84:278-85 pubmed publisher

Shimada I, LeComte M, Granger J, Quinlan N, Spees J. Self-renewal and differentiation of reactive astrocyte-derived neural stem/progenitor cells isolated from the cortical peri-infarct area after stroke. J Neurosci. 2012;32:7926-40 pubmed publisher

Wallace L, Roberts Thompson L, Reichelt J. Deletion of K1/K10 does not impair epidermal stratification but affects desmosomal structure and nuclear integrity. J Cell Sci. 2012;125:1750-8 pubmed publisher

Singh K, Shukla P, Quan A, Desjardins J, Lovren F, Pan Y, et al. BRCA2 protein deficiency exaggerates doxorubicin-induced cardiomyocyte apoptosis and cardiac failure. J Biol Chem. 2012;287:6604-14 pubmed publisher

Cheng Z, Völkers M, Din S, Avitabile D, Khan M, Gude N, et al. Mitochondrial translocation of Nur77 mediates cardiomyocyte apoptosis. Eur Heart J. 2011;32:2179-88 pubmed publisher

Lovric M, Hawkins C. TRAIL treatment provokes mutations in surviving cells. Oncogene. 2010;29:5048-60 pubmed publisher

Yin X, Wright J, Wall T, Grammas P. Brain endothelial cells synthesize neurotoxic thrombin in Alzheimer's disease. Am J Pathol. 2010;176:1600-6 pubmed publisher

Paonessa J, Munday C, Mhawech Fauceglia P, Munday R, Zhang Y. 5,6-Dihydrocyclopenta[c][1,2]-dithiole-3(4H)-thione is a promising cancer chemopreventive agent in the urinary bladder. Chem Biol Interact. 2009;180:119-26 pubmed publisher

Ashley D, Riffkin C, Lovric M, Mikeska T, Dobrovic A, Maxwell J, et al. In vitro sensitivity testing of minimally passaged and uncultured gliomas with TRAIL and/or chemotherapy drugs. Br J Cancer. 2008;99:294-304 pubmed publisher

Cnops L, Hu T, Vanden Broeck J, Burnat K, Van den Bergh G, Arckens L. Age- and experience-dependent expression of dynamin I and synaptotagmin I in cat visual system. J Comp Neurol. 2007;504:254-64 pubmed publisher

Watanabe R, Higashi S, Nonaka T, Kawakami I, Oshima K, Niizato K, et al. Intracellular dynamics of Ataxin-2 in the human brains with normal and frontotemporal lobar degeneration with TDP-43 inclusions. Acta Neuropathol Commun. 2020;8:176 pubmed publisher

Raso M, Djoric N, Walser F, Hess S, Schmid F, Burger S, et al. Interferon-stimulated gene 15 accelerates replication fork progression inducing chromosomal breakage. J Cell Biol. 2020;219: pubmed publisher

Huang T, Smith R, Bacos K, Song D, Faull R, Waldvogel H, et al. No symphony without bassoon and piccolo: changes in synaptic active zone proteins in Huntington's disease. Acta Neuropathol Commun. 2020;8:77 pubmed publisher

Kiepas A, Voorand E, Senecal J, Ahn R, Annis M, Jacquet K, et al. The SHCA adapter protein cooperates with lipoma-preferred partner in the regulation of adhesion dynamics and invadopodia formation. J Biol Chem. 2020;: pubmed publisher

Palomer X, Román Azcona M, Pizarro Delgado J, Planavila A, Villarroya F, Valenzuela Alcaraz B, et al. SIRT3-mediated inhibition of FOS through histone H3 deacetylation prevents cardiac fibrosis and inflammation. Signal Transduct Target Ther. 2020;5:14 pubmed publisher

Liu W, Li C, Tan F, Neo H, Chan Y, Low C, et al. Cerebrospinal fluid of chronic osteoarthritic patients induced interleukin-6 release in human glial cell-line T98G. BMC Anesthesiol. 2020;20:69 pubmed publisher

Karhu S, Kinnunen S, Tölli M, Välimäki M, Szabo Z, Talman V, et al. GATA4-targeted compound exhibits cardioprotective actions against doxorubicin-induced toxicity in vitro and in vivo: establishment of a chronic cardiotoxicity model using human iPSC-derived cardiomyocytes. Arch Toxicol. 2020;94:2113-2130 pubmed publisher

McNeill M, Wray J, Sala Newby G, Hindmarch C, Smith S, Ebrahimighaei R, et al. Nuclear actin regulates cell proliferation and migration via inhibition of SRF and TEAD. Biochim Biophys Acta Mol Cell Res. 2020;1867:118691 pubmed publisher

Tian C, Ohlund D, Rickelt S, Lidström T, Huang Y, Hao L, et al. Cancer Cell-Derived Matrisome Proteins Promote Metastasis in Pancreatic Ductal Adenocarcinoma. Cancer Res. 2020;80:1461-1474 pubmed publisher

Hazelbaker D, Beccard A, Angelini G, Mazzucato P, Messana A, Lam D, et al. A multiplexed gRNA piggyBac transposon system facilitates efficient induction of CRISPRi and CRISPRa in human pluripotent stem cells. Sci Rep. 2020;10:635 pubmed publisher

Arrant A, Roth J, Boyle N, Kashyap S, Hoffmann M, Murchison C, et al. Impaired β-glucocerebrosidase activity and processing in frontotemporal dementia due to progranulin mutations. Acta Neuropathol Commun. 2019;7:218 pubmed publisher

Foxall E, Staszowska A, Hirvonen L, Georgouli M, Ciccioli M, Rimmer A, et al. PAK4 Kinase Activity Plays a Crucial Role in the Podosome Ring of Myeloid Cells. Cell Rep. 2019;29:3385-3393.e6 pubmed publisher

Noce V, Battistelli C, Cozzolino A, Consalvi V, Cicchini C, Strippoli R, et al. YAP integrates the regulatory Snail/HNF4α circuitry controlling epithelial/hepatocyte differentiation. Cell Death Dis. 2019;10:768 pubmed publisher

Ren J, Smid M, Iaria J, Salvatori D, van Dam H, Zhu H, et al. Cancer-associated fibroblast-derived Gremlin 1 promotes breast cancer progression. Breast Cancer Res. 2019;21:109 pubmed publisher

Zanotelli M, Rahman Zaman A, VanderBurgh J, Taufalele P, Jain A, Erickson D, et al. Energetic costs regulated by cell mechanics and confinement are predictive of migration path during decision-making. Nat Commun. 2019;10:4185 pubmed publisher

Zhang H, Alsaleh G, Feltham J, Sun Y, Napolitano G, Riffelmacher T, et al. Polyamines Control eIF5A Hypusination, TFEB Translation, and Autophagy to Reverse B Cell Senescence. Mol Cell. 2019;76:110-125.e9 pubmed publisher

Lornage X, Schartner V, Balbueno I, Biancalana V, Willis T, Echaniz Laguna A, et al. Clinical, histological, and genetic characterization of PYROXD1-related myopathy. Acta Neuropathol Commun. 2019;7:138 pubmed publisher

Haga R, Garg R, Collu F, Borda d Agua B, Menendez S, Colomba A, et al. RhoBTB1 interacts with ROCKs and inhibits invasion. Biochem J. 2019;476:2499-2514 pubmed publisher

Tomassoni Ardori F, Fulgenzi G, Becker J, Barrick C, Palko M, Kuhn S, et al. Rbfox1 up-regulation impairs BDNF-dependent hippocampal LTP by dysregulating TrkB isoform expression levels. elife. 2019;8: pubmed publisher

Nowak M, Suenkel B, Porras P, Migotti R, Schmidt F, Kny M, et al. DCAF8, a novel MuRF1 interaction partner, promotes muscle atrophy. J Cell Sci. 2019;132: pubmed publisher

Huang H, Tsai S, Wu H, Huang H, Hsieh H, Kuo Y, et al. Chronic exposure to high fat diet triggers myelin disruption and interleukin-33 upregulation in hypothalamus. BMC Neurosci. 2019;20:33 pubmed publisher

Grozio A, Mills K, Yoshino J, Bruzzone S, Sociali G, Tokizane K, et al. Slc12a8 is a nicotinamide mononucleotide transporter. Nat Metab. 2019;1:47-57 pubmed publisher

Carrino M, Quotti Tubi L, Fregnani A, Canovas Nunes S, Barilà G, Trentin L, et al. Prosurvival autophagy is regulated by protein kinase CK1 alpha in multiple myeloma. Cell Death Discov. 2019;5:98 pubmed publisher

Hashimoto H, Wang Z, Garry G, Malladi V, Botten G, Ye W, et al. Cardiac Reprogramming Factors Synergistically Activate Genome-wide Cardiogenic Stage-Specific Enhancers. Cell Stem Cell. 2019;: pubmed publisher

Xu J, Wang H, Hu Y, Zhang Y, Wen L, Yin F, et al. Inhibition of CaMKIIα Activity Enhances Antitumor Effect of Fullerene C60 Nanocrystals by Suppression of Autophagic Degradation. Adv Sci (Weinh). 2019;6:1801233 pubmed publisher

D Acunzo P, Strappazzon F, Caruana I, Meneghetti G, Di Rita A, Simula L, et al. Reversible induction of mitophagy by an optogenetic bimodular system. Nat Commun. 2019;10:1533 pubmed publisher

Rosado Olivieri E, Anderson K, Kenty J, Melton D. YAP inhibition enhances the differentiation of functional stem cell-derived insulin-producing β cells. Nat Commun. 2019;10:1464 pubmed publisher

Julian M, Rabia L, Desai A, Arsiwala A, Gerson J, Paulson H, et al. Nature-inspired design and evolution of anti-amyloid antibodies. J Biol Chem. 2019;294:8438-8451 pubmed publisher

Judith D, Jefferies H, Boeing S, Frith D, Snijders A, Tooze S. ATG9A shapes the forming autophagosome through Arfaptin 2 and phosphatidylinositol 4-kinase IIIβ. J Cell Biol. 2019;218:1634-1652 pubmed publisher

Halvarsson C, Rörby E, Eliasson P, Lang S, Soneji S, Jönsson J. Putative role of NF-kB but not HIF-1α in hypoxia-dependent regulation of oxidative stress in hematopoietic stem and progenitor cells. Antioxid Redox Signal. 2019;: pubmed publisher

Maurer G, Heller S, Wanka C, Rieger J, Steinbach J. Knockdown of the TP53-Induced Glycolysis and Apoptosis Regulator (TIGAR) Sensitizes Glioma Cells to Hypoxia, Irradiation and Temozolomide. Int J Mol Sci. 2019;20: pubmed publisher

Li C, Huang L, Sun W, Chen Y, He M, Yue J, et al. Saikosaponin D suppresses enterovirus A71 infection by inhibiting autophagy. Signal Transduct Target Ther. 2019;4:4 pubmed publisher

Tousley A, Iuliano M, Weisman E, Sapp E, Richardson H, Vodicka P, et al. Huntingtin associates with the actin cytoskeleton and α-actinin isoforms to influence stimulus dependent morphology changes. PLoS ONE. 2019;14:e0212337 pubmed publisher

Zhang H, Brown R, Wei Y, Zhao P, Liu S, Liu X, et al. CD44 splice isoform switching determines breast cancer stem cell state. Genes Dev. 2019;33:166-179 pubmed publisher

Magtanong L, Ko P, To M, Cao J, Forcina G, Tarangelo A, et al. Exogenous Monounsaturated Fatty Acids Promote a Ferroptosis-Resistant Cell State. Cell Chem Biol. 2019;26:420-432.e9 pubmed publisher

Reed L, Indra R, Mrízová I, Moserova M, Schmeiser H, Wolf C, et al. Application of hepatic cytochrome b5/P450 reductase null (HBRN) mice to study the role of cytochrome b5 in the cytochrome P450-mediated bioactivation of the anticancer drug ellipticine. Toxicol Appl Pharmacol. 2019;366:64-74 pubmed publisher

Fão L, Mota S, Rego A. c-Src regulates Nrf2 activity through PKCδ after oxidant stimulus. Biochim Biophys Acta Mol Cell Res. 2019;1866:686-698 pubmed publisher

Musharrafieh R, Ma C, Zhang J, Hu Y, Diesing J, Marty M, et al. Validating Enterovirus D68-2Apro as an Antiviral Drug Target and the Discovery of Telaprevir as a Potent D68-2Apro Inhibitor. J Virol. 2019;93: pubmed publisher

Smith S, Sessions R, Shoemark D, Williams C, Ebrahimighaei R, McNeill M, et al. Anti-proliferative and anti-migratory effects of a novel YAP-TEAD interaction inhibitor identified using in silico molecular docking. J Med Chem. 2019;: pubmed publisher

Kriplani N, Duncan R, Leslie N. SWAP70 undergoes dynamic conformational regulation at the leading edge of migrating cells. FEBS Lett. 2019;593:395-405 pubmed publisher

Mohni K, Wessel S, Zhao R, Wojciechowski A, Luzwick J, Layden H, et al. HMCES Maintains Genome Integrity by Shielding Abasic Sites in Single-Strand DNA. Cell. 2019;176:144-153.e13 pubmed publisher

Uribe Etxebarria V, Agliano A, Unda F, Ibarretxe G. Wnt signaling reprograms metabolism in dental pulp stem cells. J Cell Physiol. 2019;234:13068-13082 pubmed publisher

Reilly M, Stokman M, Magry V, Jeanpierre C, Alves M, Paydar M, et al. Loss-of-function mutations in KIF14 cause severe microcephaly and kidney development defects in humans and zebrafish. Hum Mol Genet. 2019;28:778-795 pubmed publisher

Hey F, Andreadi C, Noble C, Patel B, Jin H, Kamata T, et al. Over-expressed, N-terminally truncated BRAF is detected in the nucleus of cells with nuclear phosphorylated MEK and ERK. Heliyon. 2018;4:e01065 pubmed publisher

Gutierrez S, Boada M. Neuropeptide-induced modulation of carcinogenesis in a metastatic breast cancer cell line (MDA-MB-231LUC+). Cancer Cell Int. 2018;18:216 pubmed publisher

Brekk O, Makridakis M, Mavroeidi P, Vlahou A, Xilouri M, Stefanis L. Impairment of chaperone-mediated autophagy affects neuronal homeostasis through altered expression of DJ-1 and CRMP-2 proteins. Mol Cell Neurosci. 2018;95:1-12 pubmed publisher

Durré T, Morfoisse F, Erpicum C, Ebroin M, Blacher S, García Caballero M, et al. uPARAP/Endo180 receptor is a gatekeeper of VEGFR-2/VEGFR-3 heterodimerisation during pathological lymphangiogenesis. Nat Commun. 2018;9:5178 pubmed publisher

Bainor A, Saini S, Calderon A, Casado Polanco R, Giner Ramirez B, Moncada C, et al. The HDAC-Associated Sin3B Protein Represses DREAM Complex Targets and Cooperates with APC/C to Promote Quiescence. Cell Rep. 2018;25:2797-2807.e8 pubmed publisher

Roh V, Abramowski P, Hiou Feige A, Cornils K, Rivals J, Zougman A, et al. Cellular Barcoding Identifies Clonal Substitution as a Hallmark of Local Recurrence in a Surgical Model of Head and Neck Squamous Cell Carcinoma. Cell Rep. 2018;25:2208-2222.e7 pubmed publisher

Hintze S, Knaier L, Limmer S, Schoser B, Meinke P. Nuclear Envelope Transmembrane Proteins in Myotonic Dystrophy Type 1. Front Physiol. 2018;9:1532 pubmed publisher

Srikanth P, Lagomarsino V, PEARSE R, Liao M, Ghosh S, Nehme R, et al. Convergence of independent DISC1 mutations on impaired neurite growth via decreased UNC5D expression. Transl Psychiatry. 2018;8:245 pubmed publisher

Moreno Vicente R, Pavón D, Martin Padura I, Català Montoro M, Díez Sánchez A, Quílez Álvarez A, et al. Caveolin-1 Modulates Mechanotransduction Responses to Substrate Stiffness through Actin-Dependent Control of YAP. Cell Rep. 2018;25:1622-1635.e6 pubmed publisher

Hara H, Seregin S, Yang D, Fukase K, Chamaillard M, Alnemri E, et al. The NLRP6 Inflammasome Recognizes Lipoteichoic Acid and Regulates Gram-Positive Pathogen Infection. Cell. 2018;175:1651-1664.e14 pubmed publisher

Jiang B, Zhang W, Yang T, Guo C, Cao D, Zhang Z, et al. Demethylation of G-Protein-Coupled Receptor 151 Promoter Facilitates the Binding of Krüppel-Like Factor 5 and Enhances Neuropathic Pain after Nerve Injury in Mice. J Neurosci. 2018;38:10535-10551 pubmed publisher

Teo K, Gómez Cuadrado L, Tenhagen M, Byron A, Rätze M, van Amersfoort M, et al. E-cadherin loss induces targetable autocrine activation of growth factor signalling in lobular breast cancer. Sci Rep. 2018;8:15454 pubmed publisher

Sharkey L, Safren N, Pithadia A, Gerson J, Dulchavsky M, Fischer S, et al. Mutant UBQLN2 promotes toxicity by modulating intrinsic self-assembly. Proc Natl Acad Sci U S A. 2018;115:E10495-E10504 pubmed publisher

Rafa Zabłocka K, Kreiner G, Bagińska M, Nalepa I. Selective Depletion of CREB in Serotonergic Neurons Affects the Upregulation of Brain-Derived Neurotrophic Factor Evoked by Chronic Fluoxetine Treatment. Front Neurosci. 2018;12:637 pubmed publisher

Buono S, Ross J, Tasfaout H, Levy Y, Kretz C, Tayefeh L, et al. Reducing dynamin 2 (DNM2) rescues DNM2-related dominant centronuclear myopathy. Proc Natl Acad Sci U S A. 2018;115:11066-11071 pubmed publisher

Vattulainen Collanus S, Southwood M, Yang X, Moore S, Ghatpande P, Morrell N, et al. Bone morphogenetic protein signaling is required for RAD51-mediated maintenance of genome integrity in vascular endothelial cells. Commun Biol. 2018;1:149 pubmed publisher

Whitlock J, Yu K, Cui Y, Hartzell H. Anoctamin 5/TMEM16E facilitates muscle precursor cell fusion. J Gen Physiol. 2018;150:1498-1509 pubmed publisher

Nygård Skalman L, Holst M, Larsson E, Lundmark R. Plasma membrane damage caused by listeriolysin O is not repaired through endocytosis of the membrane pore. Biol Open. 2018;7: pubmed publisher

Wohak L, Baranski A, Krais A, Schmeiser H, Phillips D, Arlt V. The impact of p53 function on the metabolic activation of the carcinogenic air pollutant 3-nitrobenzanthrone and its metabolites 3-aminobenzanthrone and N-hydroxy-3-aminobenzanthrone in human cells. Mutagenesis. 2018;33:311-321 pubmed publisher

Lee J, Ko Y, Chung Y, Yun N, Kim M, Kim K, et al. The acetylation of cyclin-dependent kinase 5 at lysine 33 regulates kinase activity and neurite length in hippocampal neurons. Sci Rep. 2018;8:13676 pubmed publisher

Cherif K, Gerard C, Rousseau J, Ouellet D, Chapdelaine P, Tremblay J. Increased Frataxin Expression Induced in Friedreich Ataxia Cells by Platinum TALE-VP64s or Platinum TALE-SunTag. Mol Ther Nucleic Acids. 2018;12:19-32 pubmed publisher

Uchida H, Matsumura S, Katano T, Watanabe M, Schlossmann J, Ito S. Two isoforms of cyclic GMP-dependent kinase-I exhibit distinct expression patterns in the adult mouse dorsal root ganglion. Mol Pain. 2018;14:1744806918796409 pubmed publisher

Moumne O, Chowdhurry R, Doll C, Pereira N, Hashimi M, Grindrod T, et al. Mechanism Sharing Between Genetic and Gestational Hypoxia-Induced Cardiac Anomalies. Front Cardiovasc Med. 2018;5:100 pubmed publisher

Fujiwara Y, Saito M, Robles A, Nishida M, Takeshita F, Watanabe M, et al. A Nucleolar Stress-Specific p53-miR-101 Molecular Circuit Functions as an Intrinsic Tumor-Suppressor Network. EBioMedicine. 2018;33:33-48 pubmed publisher

Masuho I, Chavali S, Muntean B, Skamangas N, Simonyan K, Patil D, et al. Molecular Deconvolution Platform to Establish Disease Mechanisms by Surveying GPCR Signaling. Cell Rep. 2018;24:557-568.e5 pubmed publisher

Sun J, Liu Y, Jia Y, Hao X, Lin W, Tran J, et al. UBE3A-mediated p18/LAMTOR1 ubiquitination and degradation regulate mTORC1 activity and synaptic plasticity. elife. 2018;7: pubmed publisher

Malik A, Miguez R, Li X, Ho Y, Feldman E, Barmada S. Matrin 3-dependent neurotoxicity is modified by nucleic acid binding and nucleocytoplasmic localization. elife. 2018;7: pubmed publisher

Prins B, Mead T, Brody J, Sveinbjörnsson G, Ntalla I, Bihlmeyer N, et al. Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6. Genome Biol. 2018;19:87 pubmed publisher

Surve M, Bhutda S, Datey A, Anil A, Rawat S, Pushpakaran A, et al. Heterogeneity in pneumolysin expression governs the fate of Streptococcus pneumoniae during blood-brain barrier trafficking. PLoS Pathog. 2018;14:e1007168 pubmed publisher

Desimio M, Giuliani E, Ferraro A, Adorno G, Doria M. In Vitro Exposure to Prostratin but Not Bryostatin-1 Improves Natural Killer Cell Functions Including Killing of CD4+ T Cells Harboring Reactivated Human Immunodeficiency Virus. Front Immunol. 2018;9:1514 pubmed publisher

De Pascalis C, Pérez González C, Seetharaman S, Boëda B, Vianay B, Burute M, et al. Intermediate filaments control collective migration by restricting traction forces and sustaining cell-cell contacts. J Cell Biol. 2018;217:3031-3044 pubmed publisher

Zukauskas A, Mrsny R, Cortés Barrantes P, Turner J, Leong J, McCormick B. Transporters MRP1 and MRP2 Regulate Opposing Inflammatory Signals To Control Transepithelial Neutrophil Migration during Streptococcus pneumoniae Lung Infection. mSphere. 2018;3: pubmed publisher

Colburn Z, Jones J. Complexes of α6β4 integrin and vimentin act as signaling hubs to regulate epithelial cell migration. J Cell Sci. 2018;131: pubmed publisher

Zhong W, Chebolu S, Darmani N. Intracellular emetic signaling evoked by the L-type Ca2+ channel agonist FPL64176 in the least shrew (Cryptotis parva). Eur J Pharmacol. 2018;834:157-168 pubmed publisher

Sanchez Pupo R, Johnston D, Penuela S. N-Glycosylation Regulates Pannexin 2 Localization but Is Not Required for Interacting with Pannexin 1. Int J Mol Sci. 2018;19: pubmed publisher

Kattah M, Shao L, Rosli Y, Shimizu H, Whang M, Advincula R, et al. A20 and ABIN-1 synergistically preserve intestinal epithelial cell survival. J Exp Med. 2018;215:1839-1852 pubmed publisher

Arrant A, Nicholson A, Zhou X, Rademakers R, Roberson E. Partial Tmem106b reduction does not correct abnormalities due to progranulin haploinsufficiency. Mol Neurodegener. 2018;13:32 pubmed publisher

Phoomak C, Silsirivanit A, Park D, Sawanyawisuth K, Vaeteewoottacharn K, Wongkham C, et al. O-GlcNAcylation mediates metastasis of cholangiocarcinoma through FOXO3 and MAN1A1. Oncogene. 2018;37:5648-5665 pubmed publisher

Martins I, Raza S, Voisin L, Dakhli H, Allouch A, Law F, et al. Anticancer chemotherapy and radiotherapy trigger both non-cell-autonomous and cell-autonomous death. Cell Death Dis. 2018;9:716 pubmed publisher

de la Chesnaye E, Manuel Apolinar L, Damasio L, Olivares A, Palomino M, Santos I, et al. Expression profiling of lipocalin-2 and 24p3 receptor in murine gonads at different developmental stages. Exp Ther Med. 2018;16:213-221 pubmed publisher

Yeh W, Chiang H, Rees H, Edge A, Liu D. In vivo base editing of post-mitotic sensory cells. Nat Commun. 2018;9:2184 pubmed publisher

Fischietti M, Arslan A, Sassano A, Saleiro D, Majchrzak Kita B, Ebine K, et al. Slfn2 Regulates Type I Interferon Responses by Modulating the NF-κB Pathway. Mol Cell Biol. 2018;38: pubmed publisher

Wall M, Collins D, Chery S, Allen Z, Pastuzyn E, George A, et al. The Temporal Dynamics of Arc Expression Regulate Cognitive Flexibility. Neuron. 2018;98:1124-1132.e7 pubmed publisher

Dudek A, Pfaff F, Bolte H, Waguia Kontchou C, Schwemmle M. Partial Inactivation of the Chromatin Remodelers SMARCA2 and SMARCA4 in Virus-Infected Cells by Caspase-Mediated Cleavage. J Virol. 2018;92: pubmed publisher

Yi Q, Bai Z, Cai B, Chen N, Chen L, Yuan T, et al. HSV‑TK/GCV can induce cytotoxicity of retinoblastoma cells through autophagy inhibition by activating MAPK/ERK. Oncol Rep. 2018;40:682-692 pubmed publisher

Charni Natan M, Solomon H, Molchadsky A, Jacob Berger A, Goldfinger N, Rotter V. Various stress stimuli rewire the profile of liver secretome in a p53-dependent manner. Cell Death Dis. 2018;9:647 pubmed publisher

Jiang H, Gao Q, Zheng W, Yin S, Wang L, Zhong L, et al. MOF influences meiotic expansion of H2AX phosphorylation and spermatogenesis in mice. PLoS Genet. 2018;14:e1007300 pubmed publisher

Vorhagen S, Kleefisch D, Persa O, Graband A, Schwickert A, Saynisch M, et al. Shared and independent functions of aPKCλ and Par3 in skin tumorigenesis. Oncogene. 2018;37:5136-5146 pubmed publisher

Gibbs K, Kalmar B, Rhymes E, Fellows A, Ahmed M, Whiting P, et al. Inhibiting p38 MAPK alpha rescues axonal retrograde transport defects in a mouse model of ALS. Cell Death Dis. 2018;9:596 pubmed publisher

de Groot J, Ratze M, van Amersfoort M, Eisemann T, Vlug E, Niklaas M, et al. αE-catenin is a candidate tumor suppressor for the development of E-cadherin-expressing lobular-type breast cancer. J Pathol. 2018;245:456-467 pubmed publisher

Jiang M, Rao R, Wang J, Wang J, Xu L, Wu L, et al. The TSC1-mTOR-PLK axis regulates the homeostatic switch from Schwann cell proliferation to myelination in a stage-specific manner. Glia. 2018;66:1947-1959 pubmed publisher

Garner E, Williams A, Stafman L, Aye J, Mroczek Musulman E, Moore B, et al. FTY720 Decreases Tumorigenesis in Group 3 Medulloblastoma Patient-Derived Xenografts. Sci Rep. 2018;8:6913 pubmed publisher

Matsui C, Deng L, Minami N, Abe T, Koike K, Shoji I. Hepatitis C Virus NS5A Protein Promotes the Lysosomal Degradation of Hepatocyte Nuclear Factor 1α via Chaperone-Mediated Autophagy. J Virol. 2018;92: pubmed publisher

Nakashima H, Tsujimura K, Irie K, Ishizu M, Pan M, Kameda T, et al. Canonical TGF-? Signaling Negatively Regulates Neuronal Morphogenesis through TGIF/Smad Complex-Mediated CRMP2 Suppression. J Neurosci. 2018;38:4791-4810 pubmed publisher

Ohno T, Aoki H, Ohno S, Nishihara M, Furusho A, Hiromatsu S, et al. Cytokine Profile of Human Abdominal Aortic Aneurysm: Involvement of JAK/STAT Pathway. Ann Vasc Dis. 2018;11:84-90 pubmed publisher

Rath N, Munro J, Cutiongco M, Jagiełło A, Gadegaard N, McGarry L, et al. Rho Kinase Inhibition by AT13148 Blocks Pancreatic Ductal Adenocarcinoma Invasion and Tumor Growth. Cancer Res. 2018;78:3321-3336 pubmed publisher

Yun S, Reynolds R, Petrof I, White A, Rivera P, Segev A, et al. Stimulation of entorhinal cortex-dentate gyrus circuitry is antidepressive. Nat Med. 2018;24:658-666 pubmed publisher

Santinon G, Brian I, Pocaterra A, Romani P, Franzolin E, Rampazzo C, et al. dNTP metabolism links mechanical cues and YAP/TAZ to cell growth and oncogene-induced senescence. EMBO J. 2018;37: pubmed publisher

Hou Z, Chen L, Fang P, Cai H, Tang H, Peng Y, et al. Mechanisms of Triptolide-Induced Hepatotoxicity and Protective Effect of Combined Use of Isoliquiritigenin: Possible Roles of Nrf2 and Hepatic Transporters. Front Pharmacol. 2018;9:226 pubmed publisher

Bruce K, Gorkhali S, Given K, Coates A, Boyle K, Macklin W, et al. Lipoprotein Lipase Is a Feature of Alternatively-Activated Microglia and May Facilitate Lipid Uptake in the CNS During Demyelination. Front Mol Neurosci. 2018;11:57 pubmed publisher

Nabet B, Roberts J, Buckley D, Paulk J, Dastjerdi S, Yang A, et al. The dTAG system for immediate and target-specific protein degradation. Nat Chem Biol. 2018;14:431-441 pubmed publisher

O Neill K, Donohue K, Omelchenko A, Firestein B. The 3' UTRs of Brain-Derived Neurotrophic Factor Transcripts Differentially Regulate the Dendritic Arbor. Front Cell Neurosci. 2018;12:60 pubmed publisher

Khan M, Jabeen N, Khan T, Hussain H, Ali A, Khan R, et al. The evolutionarily conserved genes: Tex37, Ccdc73, Prss55 and Nxt2 are dispensable for fertility in mice. Sci Rep. 2018;8:4975 pubmed publisher

Hudson C, Kimura T, Duggirala A, Sala Newby G, Newby A, Bond M. Dual Role of CREB in The Regulation of VSMC Proliferation: Mode of Activation Determines Pro- or Anti-Mitogenic Function. Sci Rep. 2018;8:4904 pubmed publisher

Maxson M, Naj X, O Meara T, Plumb J, Cowen L, Grinstein S. Integrin-based diffusion barrier separates membrane domains enabling the formation of microbiostatic frustrated phagosomes. elife. 2018;7: pubmed publisher

Archbold H, Jackson K, Arora A, Weskamp K, Tank E, Li X, et al. TDP43 nuclear export and neurodegeneration in models of amyotrophic lateral sclerosis and frontotemporal dementia. Sci Rep. 2018;8:4606 pubmed publisher

Sobajima T, Yoshimura S, Maeda T, Miyata H, Miyoshi E, Harada A. The Rab11-binding protein RELCH/KIAA1468 controls intracellular cholesterol distribution. J Cell Biol. 2018;217:1777-1796 pubmed publisher

Dias D, Kim H, Holl D, Werne Solnestam B, Lundeberg J, Carlen M, et al. Reducing Pericyte-Derived Scarring Promotes Recovery after Spinal Cord Injury. Cell. 2018;173:153-165.e22 pubmed publisher

Vion A, Alt S, Klaus Bergmann A, Szymborska A, Zheng T, Perovic T, et al. Primary cilia sensitize endothelial cells to BMP and prevent excessive vascular regression. J Cell Biol. 2018;217:1651-1665 pubmed publisher

Zhou L, Zhou L, Su L, Cao S, Xie Y, Wang N, et al. Celecoxib Ameliorates Seizure Susceptibility in Autosomal Dominant Lateral Temporal Epilepsy. J Neurosci. 2018;38:3346-3357 pubmed publisher

Wang X, Villar V, Tiu A, Upadhyay K, Cuevas S. Dopamine D2 receptor upregulates leptin and IL-6 in adipocytes. J Lipid Res. 2018;59:607-614 pubmed publisher

Behrens G, Winzen R, Rehage N, Dörrie A, Barsch M, Hoffmann A, et al. A translational silencing function of MCPIP1/Regnase-1 specified by the target site context. Nucleic Acids Res. 2018;46:4256-4270 pubmed publisher

Willis A, Indra R, Wohak L, Sozeri O, Feser K, Mrízová I, et al. The impact of chemotherapeutic drugs on the CYP1A1-catalysed metabolism of the environmental carcinogen benzo[a]pyrene: Effects in human colorectal HCT116 TP53(+/+), TP53(+/-) and TP53(-/-) cells. Toxicology. 2018;398-399:1-12 pubmed publisher

O Brien E, Selfe J, Martins A, Walters Z, Shipley J. The long non-coding RNA MYCNOS-01 regulates MYCN protein levels and affects growth of MYCN-amplified rhabdomyosarcoma and neuroblastoma cells. BMC Cancer. 2018;18:217 pubmed publisher

Gordon W, López V, Bhattacharjee S, Gil D, Díaz J, de la Losa F, et al. A Nonsteroidal Novel Formulation Targeting Inflammatory and Pruritus-Related Mediators Modulates Experimental Allergic Contact Dermatitis. Dermatol Ther (Heidelb). 2018;8:111-126 pubmed publisher

Guo D, Zhang S, Sun H, Xu X, Hao Z, Mu C, et al. Tyrosine hydroxylase down-regulation after loss of Abelson helper integration site 1 (AHI1) promotes depression via the circadian clock pathway in mice. J Biol Chem. 2018;293:5090-5101 pubmed publisher

Pohland M, Pellowska M, Asseburg H, Hagl S, Reutzel M, Joppe A, et al. MH84 improves mitochondrial dysfunction in a mouse model of early Alzheimer's disease. Alzheimers Res Ther. 2018;10:18 pubmed publisher

Filippini A, Bonini D, Giacopuzzi E, La Via L, Gangemi F, Colombi M, et al. Differential Enzymatic Activity of Rat ADAR2 Splicing Variants Is Due to Altered Capability to Interact with RNA in the Deaminase Domain. Genes (Basel). 2018;9: pubmed publisher

McIntosh A, Martin G, Huang H, Landrock D, Kier A, Schroeder F. Δ9-Tetrahydrocannabinol induces endocannabinoid accumulation in mouse hepatocytes: antagonism by Fabp1 gene ablation. J Lipid Res. 2018;59:646-657 pubmed publisher

Kabashima A, Hirsova P, Bronk S, Hernandez M, Truty M, Rizvi S, et al. Fibroblast growth factor receptor inhibition induces loss of matrix MCL1 and necrosis in cholangiocarcinoma. J Hepatol. 2018;68:1228-1238 pubmed publisher

Long C, Li H, Tiburcy M, Rodriguez Caycedo C, Kyrychenko V, Zhou H, et al. Correction of diverse muscular dystrophy mutations in human engineered heart muscle by single-site genome editing. Sci Adv. 2018;4:eaap9004 pubmed publisher

Neto F, Klaus Bergmann A, Ong Y, Alt S, Vion A, Szymborska A, et al. YAP and TAZ regulate adherens junction dynamics and endothelial cell distribution during vascular development. elife. 2018;7: pubmed publisher

Konstantinović J, Kiris E, Kota K, Kugelman Tonos J, Videnović M, Cazares L, et al. New Steroidal 4-Aminoquinolines Antagonize Botulinum Neurotoxin Serotype A in Mouse Embryonic Stem Cell Derived Motor Neurons in Postintoxication Model. J Med Chem. 2018;61:1595-1608 pubmed publisher

Reed L, Mrízová I, Bárta F, Indra R, Moserova M, Kopka K, et al. Cytochrome b 5 impacts on cytochrome P450-mediated metabolism of benzo[a]pyrene and its DNA adduct formation: studies in hepatic cytochrome b 5 /P450 reductase null (HBRN) mice. Arch Toxicol. 2018;92:1625-1638 pubmed publisher

Svarcbahs R, Julku U, Norrbacka S, Myöhänen T. Removal of prolyl oligopeptidase reduces alpha-synuclein toxicity in cells and in vivo. Sci Rep. 2018;8:1552 pubmed publisher

Garland M, Schulze C, Foe I, van der Linden W, Child M, Bogyo M. Development of an activity-based probe for acyl-protein thioesterases. PLoS ONE. 2018;13:e0190255 pubmed publisher

Frith J, Kusuma G, Carthew J, Li F, Cloonan N, Gomez G, et al. Mechanically-sensitive miRNAs bias human mesenchymal stem cell fate via mTOR signalling. Nat Commun. 2018;9:257 pubmed publisher

Sachs B, Tran H, Folse E, Caron M. Brain-region-specific Molecular Responses to Maternal Separation and Social Defeat Stress in Mice. Neuroscience. 2018;373:122-136 pubmed publisher

Yang C, Lin S, Chiang C, Wu Y, H ng W, Chang C, et al. Loss of GPNMB Causes Autosomal-Recessive Amyloidosis Cutis Dyschromica in Humans. Am J Hum Genet. 2018;102:219-232 pubmed publisher

Ishida Y, Ohta K, Naruse T, Kato H, Fukui A, Shigeishi H, et al. Candida albicans β-Glucan-Containing Particles Increase HO-1 Expression in Oral Keratinocytes via a Reactive Oxygen Species/p38 Mitogen-Activated Protein Kinase/Nrf2 Pathway. Infect Immun. 2018;86: pubmed publisher

Milligan S, Martin G, Landrock D, McIntosh A, Mackie J, Schroeder F, et al. Ablating both Fabp1 and Scp2/Scpx (TKO) induces hepatic phospholipid and cholesterol accumulation in high fat-fed mice. Biochim Biophys Acta Mol Cell Biol Lipids. 2018;1863:323-338 pubmed publisher

Zunke F, Moise A, Belur N, Gelyana E, Stojkovska I, Dzaferbegovic H, et al. Reversible Conformational Conversion of α-Synuclein into Toxic Assemblies by Glucosylceramide. Neuron. 2018;97:92-107.e10 pubmed publisher

Falcon B, Noad J, McMahon H, Randow F, Goedert M. Galectin-8-mediated selective autophagy protects against seeded tau aggregation. J Biol Chem. 2018;293:2438-2451 pubmed publisher

Unuma K, Aki T, Nagano S, Watanabe R, Uemura K. The down-regulation of cardiac contractile proteins underlies myocardial depression during sepsis and is mitigated by carbon monoxide. Biochem Biophys Res Commun. 2018;495:1668-1674 pubmed publisher

Wagner J, Christensen D, Bhattacharya A, Dawidziak D, Roganowicz M, Wan Y, et al. General Model for Retroviral Capsid Pattern Recognition by TRIM5 Proteins. J Virol. 2018;92: pubmed publisher

Bansal M, Moharir S, Sailasree S, Sirohi K, Sudhakar C, Sarathi D, et al. Optineurin promotes autophagosome formation by recruiting the autophagy-related Atg12-5-16L1 complex to phagophores containing the Wipi2 protein. J Biol Chem. 2018;293:132-147 pubmed publisher

Yang L, Li Y, Bhattacharya A, Zhang Y. PEPD is a pivotal regulator of p53 tumor suppressor. Nat Commun. 2017;8:2052 pubmed publisher

Cowling B, Prokic I, Tasfaout H, Rabai A, Humbert F, Rinaldi B, et al. Amphiphysin (BIN1) negatively regulates dynamin 2 for normal muscle maturation. J Clin Invest. 2017;127:4477-4487 pubmed publisher

Serra M, Poddighe L, Boi M, Sanna F, Piludu M, Corda M, et al. Expression of BDNF and trkB in the hippocampus of a rat genetic model of vulnerability (Roman low-avoidance) and resistance (Roman high-avoidance) to stress-induced depression. Brain Behav. 2017;7:e00861 pubmed publisher

House C, Jordan E, Hernandez L, Ozaki M, James J, Kim M, et al. NFκB Promotes Ovarian Tumorigenesis via Classical Pathways That Support Proliferative Cancer Cells and Alternative Pathways That Support ALDH+ Cancer Stem-like Cells. Cancer Res. 2017;77:6927-6940 pubmed publisher

Zou J, Zhang B, Gutmann D, Wong M. Postnatal reduction of tuberous sclerosis complex 1 expression in astrocytes and neurons causes seizures in an age-dependent manner. Epilepsia. 2017;58:2053-2063 pubmed publisher

Carapito R, Konantz M, Paillard C, Miao Z, Pichot A, Leduc M, et al. Mutations in signal recognition particle SRP54 cause syndromic neutropenia with Shwachman-Diamond-like features. J Clin Invest. 2017;127:4090-4103 pubmed publisher

Martin G, Landrock D, Chung S, Dangott L, McIntosh A, Mackie J, et al. Loss of fatty acid binding protein-1 alters the hepatic endocannabinoid system response to a high-fat diet. J Lipid Res. 2017;58:2114-2126 pubmed publisher

Yoshino H, Nohata N, Miyamoto K, Yonemori M, Sakaguchi T, Sugita S, et al. PHGDH as a Key Enzyme for Serine Biosynthesis in HIF2?-Targeting Therapy for Renal Cell Carcinoma. Cancer Res. 2017;77:6321-6329 pubmed publisher

Kyrychenko V, Kyrychenko S, Tiburcy M, Shelton J, Long C, Schneider J, et al. Functional correction of dystrophin actin binding domain mutations by genome editing. JCI Insight. 2017;2: pubmed publisher

Amin E, Liu Y, Deng S, Tan K, Chudgar N, Mayo M, et al. The RNA-editing enzyme ADAR promotes lung adenocarcinoma migration and invasion by stabilizing FAK. Sci Signal. 2017;10: pubmed publisher

Chihara K, Kato Y, Yoshiki H, Takeuchi K, Fujieda S, Sada K. Syk-dependent tyrosine phosphorylation of 3BP2 is required for optimal FcRγ-mediated phagocytosis and chemokine expression in U937 cells. Sci Rep. 2017;7:11480 pubmed publisher

Hong Y, Zhao T, Li X, Li S. Mutant Huntingtin Inhibits αB-Crystallin Expression and Impairs Exosome Secretion from Astrocytes. J Neurosci. 2017;37:9550-9563 pubmed publisher

Vujanovic M, Krietsch J, Raso M, Terraneo N, Zellweger R, Schmid J, et al. Replication Fork Slowing and Reversal upon DNA Damage Require PCNA Polyubiquitination and ZRANB3 DNA Translocase Activity. Mol Cell. 2017;67:882-890.e5 pubmed publisher

Papizan J, Garry G, Brezprozvannaya S, McAnally J, Bassel Duby R, Liu N, et al. Deficiency in Kelch protein Klhl31 causes congenital myopathy in mice. J Clin Invest. 2017;127:3730-3740 pubmed publisher

Ramirez Martinez A, Cenik B, Bezprozvannaya S, Chen B, Bassel Duby R, Liu N, et al. KLHL41 stabilizes skeletal muscle sarcomeres by nonproteolytic ubiquitination. elife. 2017;6: pubmed publisher

D Abronzo L, Bose S, Crapuchettes M, Beggs R, Vinall R, Tepper C, et al. The androgen receptor is a negative regulator of eIF4E phosphorylation at S209: implications for the use of mTOR inhibitors in advanced prostate cancer. Oncogene. 2017;36:6359-6373 pubmed publisher

Yadav A, Kumar B, Lang J, Teknos T, Kumar P. A muscle-specific protein 'myoferlin' modulates IL-6/STAT3 signaling by chaperoning activated STAT3 to nucleus. Oncogene. 2017;36:6374-6382 pubmed publisher

Ogura H, Nagatake Kobayashi Y, Adachi J, Tomonaga T, Fujita N, Katayama R. TKI-addicted ROS1-rearranged cells are destined to survival or death by the intensity of ROS1 kinase activity. Sci Rep. 2017;7:5519 pubmed publisher

Hirama T, Das R, Yang Y, Ferguson C, Won A, Yip C, et al. Phosphatidylserine dictates the assembly and dynamics of caveolae in the plasma membrane. J Biol Chem. 2017;292:14292-14307 pubmed publisher

Gocheva V, Naba A, Bhutkar A, Guardia T, Miller K, Li C, et al. Quantitative proteomics identify Tenascin-C as a promoter of lung cancer progression and contributor to a signature prognostic of patient survival. Proc Natl Acad Sci U S A. 2017;114:E5625-E5634 pubmed publisher

Pal R, Bondar V, Adamski C, Rodney G, Sardiello M. Inhibition of ERK1/2 Restores GSK3β Activity and Protein Synthesis Levels in a Model of Tuberous Sclerosis. Sci Rep. 2017;7:4174 pubmed publisher

Khin N, Lowe J, Jensen L, Burgio G. No evidence for genome editing in mouse zygotes and HEK293T human cell line using the DNA-guided Natronobacterium gregoryi Argonaute (NgAgo). PLoS ONE. 2017;12:e0178768 pubmed publisher

Rolland D, Basrur V, Jeon Y, McNeil Schwalm C, Fermin D, Conlon K, et al. Functional proteogenomics reveals biomarkers and therapeutic targets in lymphomas. Proc Natl Acad Sci U S A. 2017;114:6581-6586 pubmed publisher

Hiroyasu S, Stimac G, Hopkinson S, Jones J. Loss of ?-PIX inhibits focal adhesion disassembly and promotes keratinocyte motility via myosin light chain activation. J Cell Sci. 2017;130:2329-2343 pubmed publisher

Beirowski B, Wong K, Babetto E, Milbrandt J. mTORC1 promotes proliferation of immature Schwann cells and myelin growth of differentiated Schwann cells. Proc Natl Acad Sci U S A. 2017;114:E4261-E4270 pubmed publisher

Leduc C, Etienne Manneville S. Regulation of microtubule-associated motors drives intermediate filament network polarization. J Cell Biol. 2017;216:1689-1703 pubmed publisher

Vaishnavi A, Schubert L, Rix U, Marek L, Le A, Keysar S, et al. EGFR Mediates Responses to Small-Molecule Drugs Targeting Oncogenic Fusion Kinases. Cancer Res. 2017;77:3551-3563 pubmed publisher

Lee R, Reese C, Carmen Lopez G, Perry B, Bonner M, Zemskova M, et al. Deficient Adipogenesis of Scleroderma Patient and Healthy African American Monocytes. Front Pharmacol. 2017;8:174 pubmed publisher

Lobingier B, Hüttenhain R, Eichel K, Miller K, Ting A, von Zastrow M, et al. An Approach to Spatiotemporally Resolve Protein Interaction Networks in Living Cells. Cell. 2017;169:350-360.e12 pubmed publisher

Elverman M, Goddard M, Mack D, Snyder J, Lawlor M, Meng H, et al. Long-term effects of systemic gene therapy in a canine model of myotubular myopathy. Muscle Nerve. 2017;56:943-953 pubmed publisher

Dimchev G, Steffen A, Kage F, Dimchev V, Pernier J, Carlier M, et al. Efficiency of lamellipodia protrusion is determined by the extent of cytosolic actin assembly. Mol Biol Cell. 2017;28:1311-1325 pubmed publisher

Kage F, Winterhoff M, Dimchev V, Mueller J, Thalheim T, Freise A, et al. FMNL formins boost lamellipodial force generation. Nat Commun. 2017;8:14832 pubmed publisher

Lin A, Twitty C, Burnett R, Hofacre A, Mitchell L, Espinoza F, et al. Retroviral Replicating Vector Delivery of miR-PDL1 Inhibits Immune Checkpoint PDL1 and Enhances Immune Responses In Vitro. Mol Ther Nucleic Acids. 2017;6:221-232 pubmed publisher

Conant K, Daniele S, Bozzelli P, Abdi T, Edwards A, Szklarczyk A, et al. Matrix metalloproteinase activity stimulates N-cadherin shedding and the soluble N-cadherin ectodomain promotes classical microglial activation. J Neuroinflammation. 2017;14:56 pubmed publisher

Volpert G, Ben Dor S, Tarcic O, Duan J, Saada A, Merrill A, et al. Oxidative stress elicited by modifying the ceramide acyl chain length reduces the rate of clathrin-mediated endocytosis. J Cell Sci. 2017;130:1486-1493 pubmed publisher

Alique M, Ruiz Torres M, Bodega G, Noci M, Troyano N, Bohorquez L, et al. Microvesicles from the plasma of elderly subjects and from senescent endothelial cells promote vascular calcification. Aging (Albany NY). 2017;9:778-789 pubmed publisher

Saitoh S, Maruyama T, Yako Y, Kajita M, Fujioka Y, Ohba Y, et al. Rab5-regulated endocytosis plays a crucial role in apical extrusion of transformed cells. Proc Natl Acad Sci U S A. 2017;114:E2327-E2336 pubmed publisher

Mason J, Wei X, Fletcher G, Kiarash R, Brokx R, Hodgson R, et al. Functional characterization of CFI-402257, a potent and selective Mps1/TTK kinase inhibitor, for the treatment of cancer. Proc Natl Acad Sci U S A. 2017;114:3127-3132 pubmed publisher

Ariyoshi M, Katane M, Hamase K, Miyoshi Y, Nakane M, Hoshino A, et al. D-Glutamate is metabolized in the heart mitochondria. Sci Rep. 2017;7:43911 pubmed publisher

Elwell C, Czudnochowski N, Von Dollen J, Johnson J, Nakagawa R, Mirrashidi K, et al. Chlamydia interfere with an interaction between the mannose-6-phosphate receptor and sorting nexins to counteract host restriction. elife. 2017;6: pubmed publisher

Bulusu V, Prior N, Snaebjornsson M, Kuehne A, Sonnen K, Kress J, et al. Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development. Dev Cell. 2017;40:331-341.e4 pubmed publisher

Cao P, Aoki Y, Badri L, Walker N, Manning C, Lagstein A, et al. Autocrine lysophosphatidic acid signaling activates ?-catenin and promotes lung allograft fibrosis. J Clin Invest. 2017;127:1517-1530 pubmed publisher

Subramaniam M, Cicek M, Pitel K, Bruinsma E, Nelson Holte M, Withers S, et al. TIEG1 modulates ?-catenin sub-cellular localization and enhances Wnt signaling in bone. Nucleic Acids Res. 2017;45:5170-5182 pubmed publisher

Bonfiglio J, Fontana P, Zhang Q, Colby T, Gibbs Seymour I, Atanassov I, et al. Serine ADP-Ribosylation Depends on HPF1. Mol Cell. 2017;65:932-940.e6 pubmed publisher

Schatton D, Pla Martín D, Marx M, Hansen H, Mourier A, Nemazanyy I, et al. CLUH regulates mitochondrial metabolism by controlling translation and decay of target mRNAs. J Cell Biol. 2017;216:675-693 pubmed publisher

Nakajima H, Itakura M, Kubo T, Kaneshige A, Harada N, Izawa T, et al. Glyceraldehyde-3-phosphate Dehydrogenase (GAPDH) Aggregation Causes Mitochondrial Dysfunction during Oxidative Stress-induced Cell Death. J Biol Chem. 2017;292:4727-4742 pubmed publisher

Wang D, Hu G, Du Y, Zhang C, Lu Q, Lv N, et al. Aberrant activation of hedgehog signaling promotes cell proliferation via the transcriptional activation of forkhead Box M1 in colorectal cancer cells. J Exp Clin Cancer Res. 2017;36:23 pubmed publisher

Kong F, Saldarriaga O, Spratt H, Osorio E, Travi B, Luxon B, et al. Transcriptional Profiling in Experimental Visceral Leishmaniasis Reveals a Broad Splenic Inflammatory Environment that Conditions Macrophages toward a Disease-Promoting Phenotype. PLoS Pathog. 2017;13:e1006165 pubmed publisher

Vidal Quadras M, Holst M, Francis M, Larsson E, Hachimi M, Yau W, et al. Endocytic turnover of Rab8 controls cell polarization. J Cell Sci. 2017;130:1147-1157 pubmed publisher

Amen A, Ruiz Garzon C, Shi J, Subramanian M, Pham D, Meffert M. A Rapid Induction Mechanism for Lin28a in Trophic Responses. Mol Cell. 2017;65:490-503.e7 pubmed publisher

Chen Z, Givens C, Reader J, Tzima E. Haemodynamics Regulate Fibronectin Assembly via PECAM. Sci Rep. 2017;7:41223 pubmed publisher

Nakamura K, Aizawa K, Aung K, Yamauchi J, Tanoue A. Zebularine upregulates expression of CYP genes through inhibition of DNMT1 and PKR in HepG2 cells. Sci Rep. 2017;7:41093 pubmed publisher

Borsos B, Huliák I, Majoros H, Ujfaludi Z, Gyenis A, Pukler P, et al. Human p53 interacts with the elongating RNAPII complex and is required for the release of actinomycin D induced transcription blockage. Sci Rep. 2017;7:40960 pubmed publisher

Feng L, Puyang Z, Chen H, Liang P, Troy J, Liu X. Overexpression of Brain-Derived Neurotrophic Factor Protects Large Retinal Ganglion Cells After Optic Nerve Crush in Mice. Eneuro. 2017;4: pubmed publisher

Waxse B, Sengupta P, Hesketh G, Lippincott Schwartz J, Buss F. Myosin VI facilitates connexin 43 gap junction accretion. J Cell Sci. 2017;130:827-840 pubmed publisher

Mescher M, Jeong P, Knapp S, Rübsam M, Saynisch M, Kranen M, et al. The epidermal polarity protein Par3 is a non-cell autonomous suppressor of malignant melanoma. J Exp Med. 2017;214:339-358 pubmed publisher

Phua S, Chiba S, Suzuki M, Su E, Roberson E, Pusapati G, et al. Dynamic Remodeling of Membrane Composition Drives Cell Cycle through Primary Cilia Excision. Cell. 2017;168:264-279.e15 pubmed publisher

Layman A, Sprout S, Phillips D, Oliver P. Ndfip1 restricts Th17 cell potency by limiting lineage stability and proinflammatory cytokine production. Sci Rep. 2017;7:39649 pubmed publisher

Moorer M, Hebert C, Tomlinson R, Iyer S, Chason M, Stains J. Defective signaling, osteoblastogenesis and bone remodeling in a mouse model of connexin 43 C-terminal truncation. J Cell Sci. 2017;130:531-540 pubmed publisher

Zhou F, Huang D, Li Y, Hu G, Rao H, Lu Q, et al. Nek2A/SuFu feedback loop regulates Gli-mediated Hedgehog signaling pathway. Int J Oncol. 2017;50:373-380 pubmed publisher

Bordeleau F, Mason B, Lollis E, Mazzola M, Zanotelli M, Somasegar S, et al. Matrix stiffening promotes a tumor vasculature phenotype. Proc Natl Acad Sci U S A. 2017;114:492-497 pubmed publisher

Kaburagi T, Kizuka Y, Kitazume S, Taniguchi N. The Inhibitory Role of α2,6-Sialylation in Adipogenesis. J Biol Chem. 2017;292:2278-2286 pubmed publisher

Rath N, Morton J, Julian L, Helbig L, Kadir S, McGhee E, et al. ROCK signaling promotes collagen remodeling to facilitate invasive pancreatic ductal adenocarcinoma tumor cell growth. EMBO Mol Med. 2017;9:198-218 pubmed publisher

Kolyvas E, Rudloff M, Poruchynsky M, Landsman R, Hollevoet K, Venzon D, et al. Mesothelin-targeted immunotoxin RG7787 has synergistic anti-tumor activity when combined with taxanes. Oncotarget. 2017;8:9189-9199 pubmed publisher

Kirschmer N, Bandleon S, von Ehrlich Treuenstätt V, Hartmann S, Schaaf A, Lamprecht A, et al. TRPC4? and TRPC4? Similarly Affect Neonatal Cardiomyocyte Survival during Chronic GPCR Stimulation. PLoS ONE. 2016;11:e0168446 pubmed publisher

Wang S, Jacquemyn J, Murru S, Martinelli P, Barth E, Langer T, et al. The Mitochondrial m-AAA Protease Prevents Demyelination and Hair Greying. PLoS Genet. 2016;12:e1006463 pubmed publisher

Kristof E, Doan Xuan Q, Sárvári A, Klusóczki Á, Fischer Posovszky P, Wabitsch M, et al. Clozapine modifies the differentiation program of human adipocytes inducing browning. Transl Psychiatry. 2016;6:e963 pubmed publisher

Henssen A, Odersky A, Szymansky A, Seiler M, Althoff K, Beckers A, et al. Targeting tachykinin receptors in neuroblastoma. Oncotarget. 2017;8:430-443 pubmed publisher

Puverel S, Kiris E, Singh S, Klarmann K, Coppola V, Keller J, et al. RanBPM (RanBP9) regulates mouse c-Kit receptor level and is essential for normal development of bone marrow progenitor cells. Oncotarget. 2016;7:85109-85123 pubmed publisher

Kucab J, Hollstein M, Arlt V, Phillips D. Nutlin-3a selects for cells harbouring TP53 mutations. Int J Cancer. 2017;140:877-887 pubmed publisher

Turner J, Kashyap T, Dawson J, Gomez J, Bauer A, Grant S, et al. XPO1 inhibitor combination therapy with bortezomib or carfilzomib induces nuclear localization of IκBα and overcomes acquired proteasome inhibitor resistance in human multiple myeloma. Oncotarget. 2016;7:78896-78909 pubmed publisher

Dubey A, Copeland P. The Selenocysteine-Specific Elongation Factor Contains Unique Sequences That Are Required for Both Nuclear Export and Selenocysteine Incorporation. PLoS ONE. 2016;11:e0165642 pubmed publisher

Mataki H, Seki N, Mizuno K, Nohata N, Kamikawaji K, Kumamoto T, et al. Dual-strand tumor-suppressor microRNA-145 (miR-145-5p and miR-145-3p) coordinately targeted MTDH in lung squamous cell carcinoma. Oncotarget. 2016;7:72084-72098 pubmed publisher

O Grady G, Best H, Sztal T, Schartner V, Sanjuan Vazquez M, Donkervoort S, et al. Variants in the Oxidoreductase PYROXD1 Cause Early-Onset Myopathy with Internalized Nuclei and Myofibrillar Disorganization. Am J Hum Genet. 2016;99:1086-1105 pubmed publisher

Corton M, Avila Fernandez A, Campello L, Sanchez M, Benavides B, López Molina M, et al. Identification of the Photoreceptor Transcriptional Co-Repressor SAMD11 as Novel Cause of Autosomal Recessive Retinitis Pigmentosa. Sci Rep. 2016;6:35370 pubmed publisher

Leidecker O, Bonfiglio J, Colby T, Zhang Q, Atanassov I, Zaja R, et al. Serine is a new target residue for endogenous ADP-ribosylation on histones. Nat Chem Biol. 2016;12:998-1000 pubmed publisher

Thura M, Al Aidaroos A, Yong W, Kono K, Gupta A, Lin Y, et al. PRL3-zumab, a first-in-class humanized antibody for cancer therapy. JCI Insight. 2016;1:e87607 pubmed publisher

Liu C, Zhai X, Du H, Cao Y, Cao H, Wang Y, et al. Sorting nexin 9 (SNX9) is not essential for development and auditory function in mice. Oncotarget. 2016;7:68921-68932 pubmed publisher

Imamura T, Fujita K, Tagawa K, Ikura T, Chen X, Homma H, et al. Identification of hepta-histidine as a candidate drug for Huntington's disease by in silico-in vitro- in vivo-integrated screens of chemical libraries. Sci Rep. 2016;6:33861 pubmed publisher

Zhang X, Hou W, Epperly M, Rigatti L, Wang H, Franicola D, et al. Evolution of malignant plasmacytoma cell lines from K14E7 Fancd2-/- mouse long-term bone marrow cultures. Oncotarget. 2016;7:68449-68472 pubmed publisher

Kumamoto T, Seki N, Mataki H, Mizuno K, Kamikawaji K, Samukawa T, et al. Regulation of TPD52 by antitumor microRNA-218 suppresses cancer cell migration and invasion in lung squamous cell carcinoma. Int J Oncol. 2016;49:1870-1880 pubmed publisher

van der Mark V, Ghiboub M, Marsman C, Zhao J, van Dijk R, Hiralall J, et al. Phospholipid flippases attenuate LPS-induced TLR4 signaling by mediating endocytic retrieval of Toll-like receptor 4. Cell Mol Life Sci. 2017;74:715-730 pubmed publisher

Kwon J, Willy J, Quirin K, Wek R, Korc M, Yin X, et al. Novel role of miR-29a in pancreatic cancer autophagy and its therapeutic potential. Oncotarget. 2016;7:71635-71650 pubmed publisher

Chang L, Chen T, Chen S, Chen C, Lee C, Wu S, et al. Identification of a new class of WNT1 inhibitor: Cancer cells migration, G-quadruplex stabilization and target validation. Oncotarget. 2016;7:67986-68001 pubmed publisher

Seetharaman S, Flemyng E, Shen J, Conte M, Ridley A. The RNA-binding protein LARP4 regulates cancer cell migration and invasion. Cytoskeleton (Hoboken). 2016;73:680-690 pubmed publisher

Zhou C, Chen X, Zeng W, Peng C, Huang G, Li X, et al. Propranolol induced G0/G1/S phase arrest and apoptosis in melanoma cells via AKT/MAPK pathway. Oncotarget. 2016;7:68314-68327 pubmed publisher

Arlt V, Meinl W, Florian S, Nagy E, Bárta F, Thomann M, et al. Impact of genetic modulation of SULT1A enzymes on DNA adduct formation by aristolochic acids and 3-nitrobenzanthrone. Arch Toxicol. 2017;91:1957-1975 pubmed publisher

Bronger H, Singer J, Windmüller C, Reuning U, Zech D, Delbridge C, et al. CXCL9 and CXCL10 predict survival and are regulated by cyclooxygenase inhibition in advanced serous ovarian cancer. Br J Cancer. 2016;115:553-63 pubmed publisher

Hada M, Subramanian C, Andrews P, Kwok R. Cytosolic Ku70 regulates Bax-mediated cell death. Tumour Biol. 2016;37:13903-13914 pubmed

Feng L, Chen H, Yi J, Troy J, Zhang H, Liu X. Long-Term Protection of Retinal Ganglion Cells and Visual Function by Brain-Derived Neurotrophic Factor in Mice With Ocular Hypertension. Invest Ophthalmol Vis Sci. 2016;57:3793-802 pubmed publisher

Nandi S, Zheng H, Sharma N, Shahshahan H, Patel K, Mishra P. Lack of miR-133a Decreases Contractility of Diabetic Hearts: A Role for Novel Cross Talk Between Tyrosine Aminotransferase and Tyrosine Hydroxylase. Diabetes. 2016;65:3075-90 pubmed publisher

Yonemori M, Seki N, Yoshino H, Matsushita R, Miyamoto K, Nakagawa M, et al. Dual tumor-suppressors miR-139-5p and miR-139-3p targeting matrix metalloprotease 11 in bladder cancer. Cancer Sci. 2016;107:1233-42 pubmed publisher

Britton L, Jaskowski L, Bridle K, Santrampurwala N, Reiling J, Musgrave N, et al. Heterozygous Hfe gene deletion leads to impaired glucose homeostasis, but not liver injury in mice fed a high-calorie diet. Physiol Rep. 2016;4: pubmed publisher

Bennesch M, Segala G, Wider D, Picard D. LSD1 engages a corepressor complex for the activation of the estrogen receptor ? by estrogen and cAMP. Nucleic Acids Res. 2016;44:8655-8670 pubmed

Miyamoto K, Seki N, Matsushita R, Yonemori M, Yoshino H, Nakagawa M, et al. Tumour-suppressive miRNA-26a-5p and miR-26b-5p inhibit cell aggressiveness by regulating PLOD2 in bladder cancer. Br J Cancer. 2016;115:354-63 pubmed publisher

Nunes de Miranda S, Wilhelm T, Huber M, Zorn C. Differential Lyn-dependence of the SHIP1-deficient mast cell phenotype. Cell Commun Signal. 2016;14:12 pubmed publisher

Polak A, Kiliszek P, Sewastianik T, Szydłowski M, Jabłońska E, Białopiotrowicz E, et al. MEK Inhibition Sensitizes Precursor B-Cell Acute Lymphoblastic Leukemia (B-ALL) Cells to Dexamethasone through Modulation of mTOR Activity and Stimulation of Autophagy. PLoS ONE. 2016;11:e0155893 pubmed publisher

Mounir Z, Korn J, Westerling T, Lin F, Kirby C, Schirle M, et al. ERG signaling in prostate cancer is driven through PRMT5-dependent methylation of the Androgen Receptor. elife. 2016;5: pubmed publisher

Stepanova V, Jayaraman P, Zaitsev S, Lebedeva T, Bdeir K, Kershaw R, et al. Urokinase-type Plasminogen Activator (uPA) Promotes Angiogenesis by Attenuating Proline-rich Homeodomain Protein (PRH) Transcription Factor Activity and De-repressing Vascular Endothelial Growth Factor (VEGF) Receptor Expression. J Biol Chem. 2016;291:15029-45 pubmed publisher

Soni S, Raaijmakers A, Raaijmakers L, Damen J, van Stuijvenberg L, Vos M, et al. A Proteomics Approach to Identify New Putative Cardiac Intercalated Disk Proteins. PLoS ONE. 2016;11:e0152231 pubmed publisher

Offermann B, Knauer S, Singh A, Fernández Cachón M, Klose M, Kowar S, et al. Boolean Modeling Reveals the Necessity of Transcriptional Regulation for Bistability in PC12 Cell Differentiation. Front Genet. 2016;7:44 pubmed publisher

Galardi S, Petretich M, Pinna G, D Amico S, Loreni F, Michienzi A, et al. CPEB1 restrains proliferation of Glioblastoma cells through the regulation of p27(Kip1) mRNA translation. Sci Rep. 2016;6:25219 pubmed publisher

Galant D, Gaborit B, Desgrouas C, Abdesselam I, Bernard M, Levy N, et al. A Heterozygous ZMPSTE24 Mutation Associated with Severe Metabolic Syndrome, Ectopic Fat Accumulation, and Dilated Cardiomyopathy. Cells. 2016;5: pubmed publisher

Fernandes N, Sriram U, Gofman L, Cenna J, Ramirez S, Potula R. Methamphetamine alters microglial immune function through P2X7R signaling. J Neuroinflammation. 2016;13:91 pubmed publisher

Grecka E, Statkiewicz M, Gorska A, Biernacka M, Grygorowicz M, Masnyk M, et al. Prenyl Ammonium Salts--New Carriers for Gene Delivery: A B16-F10 Mouse Melanoma Model. PLoS ONE. 2016;11:e0153633 pubmed publisher

O Leary C, Riling C, Spruce L, Ding H, Kumar S, Deng G, et al. Ndfip-mediated degradation of Jak1 tunes cytokine signalling to limit expansion of CD4+ effector T cells. Nat Commun. 2016;7:11226 pubmed publisher

Kami D, Kitani T, Kawasaki T, Gojo S. Cardiac mesenchymal progenitors differentiate into adipocytes via Klf4 and c-Myc. Cell Death Dis. 2016;7:e2190 pubmed publisher

Matsushita R, Yoshino H, Enokida H, Goto Y, Miyamoto K, Yonemori M, et al. Regulation of UHRF1 by dual-strand tumor-suppressor microRNA-145 (miR-145-5p and miR-145-3p): Inhibition of bladder cancer cell aggressiveness. Oncotarget. 2016;7:28460-87 pubmed publisher

Fourgeaud L, Traves P, Tufail Y, Leal Bailey H, Lew E, Burrola P, et al. TAM receptors regulate multiple features of microglial physiology. Nature. 2016;532:240-244 pubmed publisher

Schlam D, Canton J, Carreño M, Kopinski H, Freeman S, Grinstein S, et al. Gliotoxin Suppresses Macrophage Immune Function by Subverting Phosphatidylinositol 3,4,5-Trisphosphate Homeostasis. MBio. 2016;7:e02242 pubmed publisher

Aizawa S, Fujiwara Y, Contu V, Hase K, Takahashi M, Kikuchi H, et al. Lysosomal putative RNA transporter SIDT2 mediates direct uptake of RNA by lysosomes. Autophagy. 2016;12:565-78 pubmed publisher

Bonini D, Mora C, Tornese P, Sala N, Filippini A, La Via L, et al. Acute Footshock Stress Induces Time-Dependent Modifications of AMPA/NMDA Protein Expression and AMPA Phosphorylation. Neural Plast. 2016;2016:7267865 pubmed publisher

Rahman A, Carey S, Kraning Rush C, Goldblatt Z, Bordeleau F, Lampi M, et al. Vinculin Regulates Directionality and Cell Polarity in 2D, 3D Matrix and 3D Microtrack Migration. Mol Biol Cell. 2016;: pubmed

Cannavo A, Liccardo D, Eguchi A, Elliott K, Traynham C, Ibetti J, et al. Myocardial pathology induced by aldosterone is dependent on non-canonical activities of G protein-coupled receptor kinases. Nat Commun. 2016;7:10877 pubmed publisher

Lorenzatti Hiles G, Bucheit A, Rubin J, Hayward A, Cates A, Day K, et al. ADAM15 Is Functionally Associated with the Metastatic Progression of Human Bladder Cancer. PLoS ONE. 2016;11:e0150138 pubmed publisher

Juo L, Liao W, Shih Y, Yang B, Liu A, Yan Y. HSPB7 interacts with dimerized FLNC and its absence results in progressive myopathy in skeletal muscles. J Cell Sci. 2016;129:1661-70 pubmed publisher

Jia L, Li B, Yu H. The Bub1-Plk1 kinase complex promotes spindle checkpoint signalling through Cdc20 phosphorylation. Nat Commun. 2016;7:10818 pubmed publisher

Lee S, Shatadal S, Griep A. Dlg-1 Interacts With and Regulates the Activities of Fibroblast Growth Factor Receptors and EphA2 in the Mouse Lens. Invest Ophthalmol Vis Sci. 2016;57:707-18 pubmed publisher

De Ford C, Heidersdorf B, Haun F, Murillo R, Friedrich T, Borner C, et al. The clerodane diterpene casearin J induces apoptosis of T-ALL cells through SERCA inhibition, oxidative stress, and interference with Notch1 signaling. Cell Death Dis. 2016;7:e2070 pubmed publisher

Botting C, Lu X, Triezenberg S. H2AX phosphorylation and DNA damage kinase activity are dispensable for herpes simplex virus replication. Virol J. 2016;13:15 pubmed publisher

Lu S, Natarajan S, Mott J, Kharbanda K, Harrison Findik D. Ceramide Induces Human Hepcidin Gene Transcription through JAK/STAT3 Pathway. PLoS ONE. 2016;11:e0147474 pubmed publisher

Mangione A, Obara I, Maiarú M, Géranton S, Tassorelli C, Ferrari E, et al. Nonparalytic botulinum molecules for the control of pain. Pain. 2016;157:1045-55 pubmed publisher

De Paoli H, Tuskan G, Yang X. An innovative platform for quick and flexible joining of assorted DNA fragments. Sci Rep. 2016;6:19278 pubmed publisher

Lin A, Li C, Xing Z, Hu Q, Liang K, Han L, et al. The LINK-A lncRNA activates normoxic HIF1? signalling in triple-negative breast cancer. Nat Cell Biol. 2016;18:213-24 pubmed publisher

Fernández Sánchez L, Lax P, Campello L, Pinilla I, Cuenca N. Astrocytes and Müller Cell Alterations During Retinal Degeneration in a Transgenic Rat Model of Retinitis Pigmentosa. Front Cell Neurosci. 2015;9:484 pubmed publisher

Yoon H, Lee J, Kim K, Mun S, Kim D, Kim H, et al. Serum Deprivation-Induced Human GM3 Synthase (hST3Gal V) Gene Expression Is Mediated by Runx2 in Human Osteoblastic MG-63 Cells. Int J Mol Sci. 2015;17: pubmed publisher

Chapman D, Stocki P, Williams D. Cyclophilin C Participates in the US2-Mediated Degradation of Major Histocompatibility Complex Class I Molecules. PLoS ONE. 2015;10:e0145458 pubmed publisher

Tamura R, Yoshihara K, Yamawaki K, Suda K, Ishiguro T, Adachi S, et al. Novel kinase fusion transcripts found in endometrial cancer. Sci Rep. 2015;5:18657 pubmed publisher

Mizuno K, Seki N, Mataki H, Matsushita R, Kamikawaji K, Kumamoto T, et al. Tumor-suppressive microRNA-29 family inhibits cancer cell migration and invasion directly targeting LOXL2 in lung squamous cell carcinoma. Int J Oncol. 2016;48:450-60 pubmed publisher

Spencer J, Jackson A, Li B, Ching C, Vonau M, Easterling R, et al. Expression and Significance of the HIP/PAP and RegIIIγ Antimicrobial Peptides during Mammalian Urinary Tract Infection. PLoS ONE. 2015;10:e0144024 pubmed publisher

Kang T, Kim H, Lee B, Shin T, Choi S, Kim Y, et al. Mica Nanoparticle, STB-HO Eliminates the Human Breast Carcinoma Cells by Regulating the Interaction of Tumor with its Immune Microenvironment. Sci Rep. 2015;5:17515 pubmed publisher

Escárcega Tame M, Martínez Vieyra I, Alonso Rangel L, Cisneros B, Winder S, Cerecedo D. Dystroglycan Depletion Impairs Actin-Dependent Functions of Differentiated Kasumi-1 Cells. PLoS ONE. 2015;10:e0144078 pubmed publisher

Iyama T, Wilson D. Elements That Regulate the DNA Damage Response of Proteins Defective in Cockayne Syndrome. J Mol Biol. 2016;428:62-78 pubmed publisher

Lake R, Boetefuer E, Won K, Fan H. The CSB chromatin remodeler and CTCF architectural protein cooperate in response to oxidative stress. Nucleic Acids Res. 2016;44:2125-35 pubmed publisher

Alsafadi S, Tourpin S, Bessoltane N, Salomé Desnoulez S, Vassal G, André F, et al. Nuclear localization of the caspase-3-cleaved form of p73 in anoikis. Oncotarget. 2016;7:12331-43 pubmed publisher

Chen R, Zhang G, Garfield S, Shi Y, Chen K, Robey P, et al. Variations in Glycogen Synthesis in Human Pluripotent Stem Cells with Altered Pluripotent States. PLoS ONE. 2015;10:e0142554 pubmed publisher

Miller J, Hafzalla G, Burkett Z, Fox C, White S. Reduced vocal variability in a zebra finch model of dopamine depletion: implications for Parkinson disease. Physiol Rep. 2015;3: pubmed publisher

Sosa García B, Vázquez Rivera V, González Flores J, Engel B, Cress W, Santiago Cardona P. The Retinoblastoma Tumor Suppressor Transcriptionally Represses Pak1 in Osteoblasts. PLoS ONE. 2015;10:e0142406 pubmed publisher

D Agostino V, Lal P, Mantelli B, Tiedje C, Zucal C, Thongon N, et al. Dihydrotanshinone-I interferes with the RNA-binding activity of HuR affecting its post-transcriptional function. Sci Rep. 2015;5:16478 pubmed publisher

Mátyás C, Németh B, Oláh A, Hidi L, Birtalan E, Kellermayer D, et al. The soluble guanylate cyclase activator cinaciguat prevents cardiac dysfunction in a rat model of type-1 diabetes mellitus. Cardiovasc Diabetol. 2015;14:145 pubmed publisher

Viganò E, Diamond C, Spreafico R, Balachander A, Sobota R, Mortellaro A. Human caspase-4 and caspase-5 regulate the one-step non-canonical inflammasome activation in monocytes. Nat Commun. 2015;6:8761 pubmed publisher

Baba I, Egi Y, Utsumi H, Kakimoto T, Suzuki K. Inhibitory effects of fasudil on renal interstitial fibrosis induced by unilateral ureteral obstruction. Mol Med Rep. 2015;12:8010-20 pubmed publisher

Bizet A, Becker Heck A, Ryan R, Weber K, Filhol E, Krug P, et al. Mutations in TRAF3IP1/IFT54 reveal a new role for IFT proteins in microtubule stabilization. Nat Commun. 2015;6:8666 pubmed publisher

Prokop S, Miller K, Drost N, Handrick S, Mathur V, Luo J, et al. Impact of peripheral myeloid cells on amyloid-β pathology in Alzheimer's disease-like mice. J Exp Med. 2015;212:1811-8 pubmed publisher

Armour C, Kersseboom S, Yoon G, Visser T. Further Insights into the Allan-Herndon-Dudley Syndrome: Clinical and Functional Characterization of a Novel MCT8 Mutation. PLoS ONE. 2015;10:e0139343 pubmed publisher

Zhang C, Ho M, Vega M, Burne T, Chong S. Prenatal ethanol exposure alters adult hippocampal VGLUT2 expression with concomitant changes in promoter DNA methylation, H3K4 trimethylation and miR-467b-5p levels. Epigenetics Chromatin. 2015;8:40 pubmed publisher

Moldavan M, Cravetchi O, Williams M, Irwin R, Aicher S, Allen C. Localization and expression of GABA transporters in the suprachiasmatic nucleus. Eur J Neurosci. 2015;42:3018-32 pubmed publisher

Min S, Chen X, Tracy T, Li Y, Zhou Y, Wang C, et al. Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits. Nat Med. 2015;21:1154-62 pubmed publisher

Pavon M, Arroyo Solera I, Tellez Gabriel M, Leon X, Virós D, Lopez M, et al. Enhanced cell migration and apoptosis resistance may underlie the association between high SERPINE1 expression and poor outcome in head and neck carcinoma patients. Oncotarget. 2015;6:29016-33 pubmed publisher

Charni M, Molchadsky A, Goldstein I, Solomon H, Tal P, Goldfinger N, et al. Novel p53 target genes secreted by the liver are involved in non-cell-autonomous regulation. Cell Death Differ. 2016;23:509-20 pubmed publisher

Li Y, Chen S, Chien C. Erythropoietin produced by genetic-modified NIH/3T3 fibroblasts enhances the survival of degenerating neurons. Brain Behav. 2015;5:e00356 pubmed publisher

Mitou G, Frentzel J, Desquesnes A, Le Gonidec S, Alsaati T, Beau I, et al. Targeting autophagy enhances the anti-tumoral action of crizotinib in ALK-positive anaplastic large cell lymphoma. Oncotarget. 2015;6:30149-64 pubmed publisher

Brigger D, Schläfli A, Garattini E, Tschan M. Activation of RARα induces autophagy in SKBR3 breast cancer cells and depletion of key autophagy genes enhances ATRA toxicity. Cell Death Dis. 2015;6:e1861 pubmed publisher

Hwang S, Disatnik M, Mochly Rosen D. Impaired GAPDH-induced mitophagy contributes to the pathology of Huntington's disease. EMBO Mol Med. 2015;7:1307-26 pubmed publisher

Puhr M, Hoefer J, Eigentler A, Dietrich D, van Leenders G, Uhl B, et al. PIAS1 is a determinant of poor survival and acts as a positive feedback regulator of AR signaling through enhanced AR stabilization in prostate cancer. Oncogene. 2016;35:2322-32 pubmed publisher

Krawczyk K, Yao Mattisson I, Ekman M, Oskolkov N, Grantinge R, Kotowska D, et al. Myocardin Family Members Drive Formation of Caveolae. PLoS ONE. 2015;10:e0133931 pubmed publisher

Aminkeng F, Bhavsar A, Visscher H, Rassekh S, Li Y, Lee J, et al. A coding variant in RARG confers susceptibility to anthracycline-induced cardiotoxicity in childhood cancer. Nat Genet. 2015;47:1079-84 pubmed publisher

Garcia Alvarez G, Shetty M, Lu B, Yap K, Oh Hora M, Sajikumar S, et al. Impaired spatial memory and enhanced long-term potentiation in mice with forebrain-specific ablation of the Stim genes. Front Behav Neurosci. 2015;9:180 pubmed publisher

Oku Y, Nishiya N, Shito T, Yamamoto R, Yamamoto Y, Oyama C, et al. Small molecules inhibiting the nuclear localization of YAP/TAZ for chemotherapeutics and chemosensitizers against breast cancers. FEBS Open Bio. 2015;5:542-9 pubmed publisher

Kim A, Davis R, Higuchi M. Intracellular oxygen determined by respiration regulates localization of Ras and prenylated proteins. Cell Death Dis. 2015;6:e1825 pubmed publisher

Al Sawalha N, Pokkunuri I, Omoluabi O, Kim H, Thanawala V, Hernandez A, et al. Epinephrine Activation of the β2-Adrenoceptor Is Required for IL-13-Induced Mucin Production in Human Bronchial Epithelial Cells. PLoS ONE. 2015;10:e0132559 pubmed publisher

Fuhrmann A, Engler A. The cytoskeleton regulates cell attachment strength. Biophys J. 2015;109:57-65 pubmed publisher

Schläfli A, Berezowska S, Adams O, Langer R, Tschan M. Reliable LC3 and p62 autophagy marker detection in formalin fixed paraffin embedded human tissue by immunohistochemistry. Eur J Histochem. 2015;59:2481 pubmed publisher

Szlachcic W, Switonski P, Krzyzosiak W, Figlerowicz M, Figiel M. Huntington disease iPSCs show early molecular changes in intracellular signaling, the expression of oxidative stress proteins and the p53 pathway. Dis Model Mech. 2015;8:1047-57 pubmed publisher

Faggi F, Codenotti S, Poliani P, Cominelli M, Chiarelli N, Colombi M, et al. MURC/cavin-4 Is Co-Expressed with Caveolin-3 in Rhabdomyosarcoma Tumors and Its Silencing Prevents Myogenic Differentiation in the Human Embryonal RD Cell Line. PLoS ONE. 2015;10:e0130287 pubmed publisher

Liu S, Niger C, Koh E, Stains J. Connexin43 Mediated Delivery of ADAMTS5 Targeting siRNAs from Mesenchymal Stem Cells to Synovial Fibroblasts. PLoS ONE. 2015;10:e0129999 pubmed publisher

Rodrigues Díez R, Rayego Mateos S, Orejudo M, Aroeira L, Selgas R, Ortiz A, et al. TGF-Beta Blockade Increases Renal Inflammation Caused by the C-Terminal Module of the CCN2. Mediators Inflamm. 2015;2015:506041 pubmed publisher

Moghimi E, Solomon J, Gianforcaro A, Hamadeh M. Dietary Vitamin D3 Restriction Exacerbates Disease Pathophysiology in the Spinal Cord of the G93A Mouse Model of Amyotrophic Lateral Sclerosis. PLoS ONE. 2015;10:e0126355 pubmed publisher

Yoshimura K, Nagasawa A, Kudo J, Onoda M, Morikage N, Furutani A, et al. Inhibitory effect of statins on inflammation-related pathways in human abdominal aortic aneurysm tissue. Int J Mol Sci. 2015;16:11213-28 pubmed publisher

Ding Z, Huang H. Mesenchymal stem cells in rabbit meniscus and bone marrow exhibit a similar feature but a heterogeneous multi-differentiation potential: superiority of meniscus as a cell source for meniscus repair. BMC Musculoskelet Disord. 2015;16:65 pubmed publisher

Ahronian L, Driscoll D, Klimstra D, Lewis B. The p53R172H mutant does not enhance hepatocellular carcinoma development and progression. PLoS ONE. 2015;10:e0123816 pubmed publisher

Boivin N, Baillargeon J, Doss P, Roy A, Rangachari M. Interferon-β suppresses murine Th1 cell function in the absence of antigen-presenting cells. PLoS ONE. 2015;10:e0124802 pubmed publisher

Kim M, James J, Annunziata C. Topotecan synergizes with CHEK1 (CHK1) inhibitor to induce apoptosis in ovarian cancer cells. BMC Cancer. 2015;15:196 pubmed publisher

Olguín Albuerne M, Morán J. ROS produced by NOX2 control in vitro development of cerebellar granule neurons development. ASN Neuro. 2015;7: pubmed publisher

Ohashi M, Holthaus A, Calderwood M, Lai C, Krastins B, Sarracino D, et al. The EBNA3 family of Epstein-Barr virus nuclear proteins associates with the USP46/USP12 deubiquitination complexes to regulate lymphoblastoid cell line growth. PLoS Pathog. 2015;11:e1004822 pubmed publisher

Yamada A, Aki T, Unuma K, Funakoshi T, Uemura K. Paraquat induces epithelial-mesenchymal transition-like cellular response resulting in fibrogenesis and the prevention of apoptosis in human pulmonary epithelial cells. PLoS ONE. 2015;10:e0120192 pubmed publisher

Mazumdar S, Arendt L, Phillips S, Sedic M, Kuperwasser C, Gill G. CoREST1 promotes tumor formation and tumor stroma interactions in a mouse model of breast cancer. PLoS ONE. 2015;10:e0121281 pubmed publisher

Brulhart Meynet M, Braunersreuther V, Brinck J, Montecucco F, Prost J, Thomas A, et al. Improving reconstituted HDL composition for efficient post-ischemic reduction of ischemia reperfusion injury. PLoS ONE. 2015;10:e0119664 pubmed publisher

Lin B, Lee H, Yoon J, Madan A, Wayner E, Tonning S, et al. Global analysis of H3K4me3 and H3K27me3 profiles in glioblastoma stem cells and identification of SLC17A7 as a bivalent tumor suppressor gene. Oncotarget. 2015;6:5369-81 pubmed

Herraiz Martínez A, Álvarez García J, Llach A, Molina C, Fernandes J, Ferrero Gregori A, et al. Ageing is associated with deterioration of calcium homeostasis in isolated human right atrial myocytes. Cardiovasc Res. 2015;106:76-86 pubmed publisher

Ramos Chávez L, Rendón López C, Zepeda A, Silva Adaya D, Del Razo L, Gonsebatt M. Neurological effects of inorganic arsenic exposure: altered cysteine/glutamate transport, NMDA expression and spatial memory impairment. Front Cell Neurosci. 2015;9:21 pubmed publisher

Peretz Y, Wu H, Patel S, Bellacosa A, Katz R. Inhibitor of DNA Binding 4 (ID4) is highly expressed in human melanoma tissues and may function to restrict normal differentiation of melanoma cells. PLoS ONE. 2015;10:e0116839 pubmed publisher

Dabul S, Bathgate Siryk A, Valero T, Jafferjee M, Sturchler E, McDonald P, et al. Suppression of adrenal βarrestin1-dependent aldosterone production by ARBs: head-to-head comparison. Sci Rep. 2015;5:8116 pubmed publisher

Chen X, Wales P, Quinti L, Zuo F, Moniot S, Herisson F, et al. The sirtuin-2 inhibitor AK7 is neuroprotective in models of Parkinson's disease but not amyotrophic lateral sclerosis and cerebral ischemia. PLoS ONE. 2015;10:e0116919 pubmed publisher

Domínguez Alonso A, Valdés Tovar M, Solís Chagoyán H, Benítez King G. Melatonin stimulates dendrite formation and complexity in the hilar zone of the rat hippocampus: participation of the Ca++/Calmodulin complex. Int J Mol Sci. 2015;16:1907-27 pubmed publisher

Kizuka Y, Kitazume S, Fujinawa R, Saito T, Iwata N, Saido T, et al. An aberrant sugar modification of BACE1 blocks its lysosomal targeting in Alzheimer's disease. EMBO Mol Med. 2015;7:175-89 pubmed publisher

Kawalec M, Zabłocka B, Kabzińska D, Neska J, Beręsewicz M. Mitofusin 2 expression dominates over mitofusin 1 exclusively in mouse dorsal root ganglia - a possible explanation for peripheral nervous system involvement in Charcot-Marie-Tooth 2A. Folia Neuropathol. 2014;52:436-42 pubmed

Sidorova Darmos E, Wither R, Shulyakova N, Fisher C, Ratnam M, Aarts M, et al. Differential expression of sirtuin family members in the developing, adult, and aged rat brain. Front Aging Neurosci. 2014;6:333 pubmed publisher

Guzzo G, Sciacovelli M, Bernardi P, Rasola A. Inhibition of succinate dehydrogenase by the mitochondrial chaperone TRAP1 has anti-oxidant and anti-apoptotic effects on tumor cells. Oncotarget. 2014;5:11897-908 pubmed

Tange S, Oktyabri D, Terashima M, Ishimura A, Suzuki T. JARID2 is involved in transforming growth factor-beta-induced epithelial-mesenchymal transition of lung and colon cancer cell lines. PLoS ONE. 2014;9:e115684 pubmed publisher

Mataki H, Seki N, Chiyomaru T, Enokida H, Goto Y, Kumamoto T, et al. Tumor-suppressive microRNA-206 as a dual inhibitor of MET and EGFR oncogenic signaling in lung squamous cell carcinoma. Int J Oncol. 2015;46:1039-50 pubmed publisher

Tsutsui Kimura I, Yoshida T, Ohmura Y, Izumi T, Yoshioka M. Milnacipran remediates impulsive deficits in rats with lesions of the ventromedial prefrontal cortex. Int J Neuropsychopharmacol. 2014;18: pubmed publisher

Iyama T, Lee S, Berquist B, Gileadi O, Bohr V, Seidman M, et al. CSB interacts with SNM1A and promotes DNA interstrand crosslink processing. Nucleic Acids Res. 2015;43:247-58 pubmed publisher

Chakraborty S, Li L, Puliyappadamba V, Guo G, Hatanpaa K, Mickey B, et al. Constitutive and ligand-induced EGFR signalling triggers distinct and mutually exclusive downstream signalling networks. Nat Commun. 2014;5:5811 pubmed publisher

Grande V, Manassero G, Vercelli A. Neuroprotective and anti-inflammatory roles of the phosphatase and tensin homolog deleted on chromosome Ten (PTEN) Inhibition in a Mouse Model of Temporal Lobe Epilepsy. PLoS ONE. 2014;9:e114554 pubmed publisher

Afshordel S, Kern B, Clasohm J, König H, Priester M, Weissenberger J, et al. Lovastatin and perillyl alcohol inhibit glioma cell invasion, migration, and proliferation--impact of Ras-/Rho-prenylation. Pharmacol Res. 2015;91:69-77 pubmed publisher

Schumacher M, Feng R, Aihara E, Engevik A, Montrose M, Ottemann K, et al. Helicobacter pylori-induced Sonic Hedgehog expression is regulated by NFκB pathway activation: the use of a novel in vitro model to study epithelial response to infection. Helicobacter. 2015;20:19-28 pubmed publisher

Law R, Dixon Salazar T, Jerber J, Cai N, Abbasi A, Zaki M, et al. Biallelic truncating mutations in FMN2, encoding the actin-regulatory protein Formin 2, cause nonsyndromic autosomal-recessive intellectual disability. Am J Hum Genet. 2014;95:721-8 pubmed publisher

Kim M, Min D, Wright G, Goldlust I, Annunziata C. Loss of compensatory pro-survival and anti-apoptotic modulator, IKKε, sensitizes ovarian cancer cells to CHEK1 loss through an increased level of p21. Oncotarget. 2014;5:12788-802 pubmed

Akaishi R, Nakabayashi K, Nishihara H, Furuta I, Kojima T, Morikawa M, et al. Autophagy in the placenta of women with hypertensive disorders in pregnancy. Placenta. 2014;35:974-80 pubmed publisher

Duggirala A, Kimura T, Sala Newby G, Johnson J, Wu Y, Newby A, et al. cAMP-induced actin cytoskeleton remodelling inhibits MKL1-dependent expression of the chemotactic and pro-proliferative factor, CCN1. J Mol Cell Cardiol. 2015;79:157-68 pubmed publisher

Cepeda C, Chang J, Owens G, Huynh M, Chen J, Tran C, et al. In Rasmussen encephalitis, hemichannels associated with microglial activation are linked to cortical pyramidal neuron coupling: a possible mechanism for cellular hyperexcitability. CNS Neurosci Ther. 2015;21:152-63 pubmed publisher

Singh S, Simpson R, Bennett R. Relaxin activates peroxisome proliferator-activated receptor γ (PPARγ) through a pathway involving PPARγ coactivator 1α (PGC1α). J Biol Chem. 2015;290:950-9 pubmed publisher

Puleston D, Zhang H, Powell T, Lipina E, Sims S, Panse I, et al. Autophagy is a critical regulator of memory CD8(+) T cell formation. elife. 2014;3: pubmed publisher

Flinn J, Bozzelli P, Adlard P, Railey A. Spatial memory deficits in a mouse model of late-onset Alzheimer's disease are caused by zinc supplementation and correlate with amyloid-beta levels. Front Aging Neurosci. 2014;6:174 pubmed publisher

Cutting A, Del Rosario Y, Mu R, Rodriguez A, Till A, Subramani S, et al. The role of autophagy during group B Streptococcus infection of blood-brain barrier endothelium. J Biol Chem. 2014;289:35711-23 pubmed publisher

Woodham A, Raff A, Da Silva D, Kast W. Molecular analysis of human papillomavirus virus-like particle activated Langerhans cells in vitro. Methods Mol Biol. 2015;1249:135-49 pubmed publisher

Baumann C, Rogers R, Gahlot N, Ingalls C. Eccentric contractions disrupt FKBP12 content in mouse skeletal muscle. Physiol Rep. 2014;2: pubmed publisher

Ko S, Ko H, Shieh T, Chang W, Chen H, Chang S, et al. Cell migration is regulated by AGE-RAGE interaction in human oral cancer cells in vitro. PLoS ONE. 2014;9:e110542 pubmed publisher

Nikolopoulou E, Papacleovoulou G, Jean Alphonse F, Grimaldi G, Parker M, Hanyaloglu A, et al. Arachidonic acid-dependent gene regulation during preadipocyte differentiation controls adipocyte potential. J Lipid Res. 2014;55:2479-90 pubmed publisher

Braeuning A, Bucher P, Hofmann U, Buchmann A, Schwarz M. Chemically induced mouse liver tumors are resistant to treatment with atorvastatin. BMC Cancer. 2014;14:766 pubmed publisher

Wiernasz E, Kaliszewska A, Brutkowski W, Bednarczyk J, Gorniak M, Kaza B, et al. Ttyh1 protein is expressed in glia in vitro and shows elevated expression in activated astrocytes following status epilepticus. Neurochem Res. 2014;39:2516-26 pubmed publisher

Rosendahl A, Gundewar C, Said Hilmersson K, Ni L, Saleem M, Andersson R. Conditionally immortalized human pancreatic stellate cell lines demonstrate enhanced proliferation and migration in response to IGF-I. Exp Cell Res. 2015;330:300-10 pubmed publisher

Johnson J, Jenkins N, Huang W, Di Gregoli K, Sala Newby G, Scholtes V, et al. Relationship of MMP-14 and TIMP-3 expression with macrophage activation and human atherosclerotic plaque vulnerability. Mediators Inflamm. 2014;2014:276457 pubmed publisher

Lew E, Oh J, Burrola P, Lax I, Zagórska A, Través P, et al. Differential TAM receptor-ligand-phospholipid interactions delimit differential TAM bioactivities. elife. 2014;3: pubmed publisher

Payne L, Eves R, Jia L, Mak A. p53 Down regulates PDGF-induced formation of circular dorsal ruffles in rat aortic smooth muscle cells. PLoS ONE. 2014;9:e108257 pubmed publisher

Molosh A, Johnson P, Spence J, Arendt D, Federici L, Bernabe C, et al. Social learning and amygdala disruptions in Nf1 mice are rescued by blocking p21-activated kinase. Nat Neurosci. 2014;17:1583-90 pubmed publisher

Yeves A, Villa Abrille M, Pérez N, Medina A, Escudero E, Ennis I. Physiological cardiac hypertrophy: critical role of AKT in the prevention of NHE-1 hyperactivity. J Mol Cell Cardiol. 2014;76:186-95 pubmed publisher

Young J, Kretchmer K, Ondeck M, Zambon A, Engler A. Mechanosensitive kinases regulate stiffness-induced cardiomyocyte maturation. Sci Rep. 2014;4:6425 pubmed publisher

Krais A, Mühlbauer K, Kucab J, Chinbuah H, Cornelius M, Wei Q, et al. Comparison of the metabolic activation of environmental carcinogens in mouse embryonic stem cells and mouse embryonic fibroblasts. Toxicol In Vitro. 2015;29:34-43 pubmed publisher

Korotchenko S, Cingolani L, Kuznetsova T, Bologna L, Chiappalone M, Dityatev A. Modulation of network activity and induction of homeostatic synaptic plasticity by enzymatic removal of heparan sulfates. Philos Trans R Soc Lond B Biol Sci. 2014;369:20140134 pubmed publisher

Smith S, Petrova A, Madden M, Wang H, Pan Y, Warren M, et al. A gemcitabine sensitivity screen identifies a role for NEK9 in the replication stress response. Nucleic Acids Res. 2014;42:11517-27 pubmed publisher

Zeng C, Wang Y, Lu Q, Chen J, Zhang J, Liu T, et al. SPOP suppresses tumorigenesis by regulating Hedgehog/Gli2 signaling pathway in gastric cancer. J Exp Clin Cancer Res. 2014;33:75 pubmed publisher

Zagórska A, Través P, Lew E, Dransfield I, Lemke G. Diversification of TAM receptor tyrosine kinase function. Nat Immunol. 2014;15:920-8 pubmed publisher

Pinacho R, Valdizán E, Pilar Cuéllar F, Prades R, Tarragó T, Haro J, et al. Increased SP4 and SP1 transcription factor expression in the postmortem hippocampus of chronic schizophrenia. J Psychiatr Res. 2014;58:189-96 pubmed publisher

Althoff K, Beckers A, Bell E, Nortmeyer M, Thor T, Sprüssel A, et al. A Cre-conditional MYCN-driven neuroblastoma mouse model as an improved tool for preclinical studies. Oncogene. 2015;34:3357-68 pubmed publisher

DuSablon A, Kent S, Coburn A, Virag J. EphA2-receptor deficiency exacerbates myocardial infarction and reduces survival in hyperglycemic mice. Cardiovasc Diabetol. 2014;13:114 pubmed publisher

Dixon Salazar T, Fourgeaud L, Tyler C, Poole J, Park J, Boulanger L. MHC class I limits hippocampal synapse density by inhibiting neuronal insulin receptor signaling. J Neurosci. 2014;34:11844-56 pubmed publisher

Ishizuka A, Hasegawa Y, Ishida K, Yanaka K, Nakagawa S. Formation of nuclear bodies by the lncRNA Gomafu-associating proteins Celf3 and SF1. Genes Cells. 2014;19:704-21 pubmed publisher

Chen L, Miao Y, Chen L, Xu J, Wang X, Zhao H, et al. The role of low levels of fullerene C60 nanocrystals on enhanced learning and memory of rats through persistent CaMKII activation. Biomaterials. 2014;35:9269-79 pubmed publisher

Hagl S, Grewal R, Ciobanu I, Helal A, Khayyal M, Muller W, et al. Rice bran extract compensates mitochondrial dysfunction in a cellular model of early Alzheimer's disease. J Alzheimers Dis. 2015;43:927-38 pubmed publisher

Menon M, Sawada A, Chaturvedi A, Mishra P, Schuster Gossler K, Galla M, et al. Genetic deletion of SEPT7 reveals a cell type-specific role of septins in microtubule destabilization for the completion of cytokinesis. PLoS Genet. 2014;10:e1004558 pubmed publisher

Baens M, Bonsignore L, Somers R, Vanderheydt C, Weeks S, Gunnarsson J, et al. MALT1 auto-proteolysis is essential for NF-κB-dependent gene transcription in activated lymphocytes. PLoS ONE. 2014;9:e103774 pubmed publisher

Nakajima A, Ito Y, Tanaka E, Sano R, Karasawa Y, Maeno M, et al. Functional role of TGF-? receptors during palatal fusion in vitro. Arch Oral Biol. 2014;59:1192-204 pubmed publisher

Isakov E, Weisman Shomer P, Benhar M. Suppression of the pro-inflammatory NLRP3/interleukin-1? pathway in macrophages by the thioredoxin reductase inhibitor auranofin. Biochim Biophys Acta. 2014;1840:3153-61 pubmed publisher

Gyenis A, Umlauf D, Ujfaludi Z, Boros I, Ye T, Tora L. UVB induces a genome-wide acting negative regulatory mechanism that operates at the level of transcription initiation in human cells. PLoS Genet. 2014;10:e1004483 pubmed publisher

Starr A, Sand C, Heikal L, Kelly P, Spina D, Crabtree M, et al. Overexpression of GTP cyclohydrolase 1 feedback regulatory protein is protective in a murine model of septic shock. Shock. 2014;42:432-9 pubmed publisher

Haimovici A, Brigger D, Torbett B, Fey M, Tschan M. Induction of the autophagy-associated gene MAP1S via PU.1 supports APL differentiation. Leuk Res. 2014;38:1041-7 pubmed publisher

Li Q, Liu L, Zhang Q, Liu S, Ge D, You Z. Interleukin-17 Indirectly Promotes M2 Macrophage Differentiation through Stimulation of COX-2/PGE2 Pathway in the Cancer Cells. Cancer Res Treat. 2014;46:297-306 pubmed publisher

Neshati Z, Liu J, Zhou G, Schalij M, de Vries A. Development of a lentivirus vector-based assay for non-destructive monitoring of cell fusion activity. PLoS ONE. 2014;9:e102433 pubmed publisher

Brunel J, Chopy D, Dosnon M, Bloyet L, Devaux P, Urzua E, et al. Sequence of events in measles virus replication: role of phosphoprotein-nucleocapsid interactions. J Virol. 2014;88:10851-63 pubmed publisher

Capaccione K, Hong X, Morgan K, Liu W, Bishop J, Liu L, et al. Sox9 mediates Notch1-induced mesenchymal features in lung adenocarcinoma. Oncotarget. 2014;5:3636-50 pubmed

Brown N, Rolland D, McHugh J, Weigelin H, Zhao L, Lim M, et al. Activating FGFR2-RAS-BRAF mutations in ameloblastoma. Clin Cancer Res. 2014;20:5517-26 pubmed publisher

Shin S, Kwon Y, Heo S, Jeong G, Kim B, Seo E, et al. Krüppel-like factor 4 mediates lysophosphatidic acid-stimulated migration and proliferation of PC3M prostate cancer cells. Exp Mol Med. 2014;46:e104 pubmed publisher

Brigger D, Proikas Cezanne T, Tschan M. WIPI-dependent autophagy during neutrophil differentiation of NB4 acute promyelocytic leukemia cells. Cell Death Dis. 2014;5:e1315 pubmed publisher

Kang T, Choi S, Yang S, Shin T, Kim H, Yu K, et al. Growth arrest and forced differentiation of human primary glioblastoma multiforme by a novel small molecule. Sci Rep. 2014;4:5546 pubmed publisher

Salisbury T, Tomblin J, Primerano D, Boskovic G, Fan J, Mehmi I, et al. Endogenous aryl hydrocarbon receptor promotes basal and inducible expression of tumor necrosis factor target genes in MCF-7 cancer cells. Biochem Pharmacol. 2014;91:390-9 pubmed publisher

THRAILKILL K, Bunn R, LUMPKIN C, Wahl E, Cockrell G, Morris L, et al. Loss of insulin receptor in osteoprogenitor cells impairs structural strength of bone. J Diabetes Res. 2014;2014:703589 pubmed publisher

Kou B, Gao Y, Du C, Shi Q, Xu S, Wang C, et al. miR-145 inhibits invasion of bladder cancer cells by targeting PAK1. Urol Oncol. 2014;32:846-54 pubmed publisher

Hays T, Ma ayan A, Clark N, Tan C, Teixeira A, Teixeira A, et al. Proteomics analysis of the non-muscle myosin heavy chain IIa-enriched actin-myosin complex reveals multiple functions within the podocyte. PLoS ONE. 2014;9:e100660 pubmed publisher

Treude F, Kappes F, Fahrenkamp D, Muller Newen G, Dajas Bailador F, Kramer O, et al. Caspase-8-mediated PAR-4 cleavage is required for TNF?-induced apoptosis. Oncotarget. 2014;5:2988-98 pubmed

Occhi G, Regazzo D, Albiger N, Ceccato F, Ferasin S, Scanarini M, et al. Activation of the dopamine receptor type-2 (DRD2) promoter by 9-cis retinoic acid in a cellular model of Cushing's disease mediates the inhibition of cell proliferation and ACTH secretion without a complete corticotroph-to-melanotroph transdifferenti. Endocrinology. 2014;155:3538-49 pubmed publisher

Zhao C, Pavicic P, Datta S, Sun D, Novotny M, Hamilton T. Cellular stress amplifies TLR3/4-induced CXCL1/2 gene transcription in mononuclear phagocytes via RIPK1. J Immunol. 2014;193:879-88 pubmed publisher

Lavigne A, Castells M, Mermet J, Kocanova S, Dalvai M, Bystricky K. Increased macroH2A1.1 expression correlates with poor survival of triple-negative breast cancer patients. PLoS ONE. 2014;9:e98930 pubmed publisher

McLean J, Smith G, Rocha E, Osborn T, Dib S, Hayes M, et al. ALS-associated peripherin spliced transcripts form distinct protein inclusions that are neuroprotective against oxidative stress. Exp Neurol. 2014;261:217-29 pubmed publisher

Shin H, Tilahun M, Cho O, Chandiran K, Kuksin C, Keerthivasan S, et al. NOTCH1 Can Initiate NF-?B Activation via Cytosolic Interactions with Components of the T Cell Signalosome. Front Immunol. 2014;5:249 pubmed publisher

Mancuso R, del Valle J, Morell M, Pallas M, Osta R, Navarro X. Lack of synergistic effect of resveratrol and sigma-1 receptor agonist (PRE-084) in SOD1G?³A ALS mice: overlapping effects or limited therapeutic opportunity?. Orphanet J Rare Dis. 2014;9:78 pubmed publisher

Sluka S, Akhmedov A, Vogel J, Unruh D, Bogdanov V, Camici G, et al. Alternatively spliced tissue factor is not sufficient for embryonic development. PLoS ONE. 2014;9:e97793 pubmed publisher

Barucker C, Harmeier A, Weiske J, Fauler B, Albring K, Prokop S, et al. Nuclear translocation uncovers the amyloid peptide A?42 as a regulator of gene transcription. J Biol Chem. 2014;289:20182-91 pubmed publisher

Penna C, Brancaccio M, Tullio F, Rubinetto C, Perrelli M, Angotti C, et al. Overexpression of the muscle-specific protein, melusin, protects from cardiac ischemia/reperfusion injury. Basic Res Cardiol. 2014;109:418 pubmed publisher

Tabuchi Y, Yunoki T, Hoshi N, Suzuki N, Kondo T. Genes and gene networks involved in sodium fluoride-elicited cell death accompanying endoplasmic reticulum stress in oral epithelial cells. Int J Mol Sci. 2014;15:8959-78 pubmed publisher

Makia N, Surapureddi S, Monostory K, Prough R, Goldstein J. Regulation of human CYP2C9 expression by electrophilic stress involves activator protein 1 activation and DNA looping. Mol Pharmacol. 2014;86:125-37 pubmed publisher

Sun T, Co N, Wong N. PFTK1 interacts with cyclin Y to activate non-canonical Wnt signaling in hepatocellular carcinoma. Biochem Biophys Res Commun. 2014;449:163-8 pubmed publisher

Lee S, Griep A. Loss of Dlg-1 in the mouse lens impairs fibroblast growth factor receptor signaling. PLoS ONE. 2014;9:e97470 pubmed publisher

Ciscato F, Sciacovelli M, Villano G, Turato C, Bernardi P, Rasola A, et al. SERPINB3 protects from oxidative damage by chemotherapeutics through inhibition of mitochondrial respiratory complex I. Oncotarget. 2014;5:2418-27 pubmed

O Neal W, Griffin W, Kent S, Faiz F, HODGES J, Vuncannon J, et al. Deletion of the EphA2 receptor exacerbates myocardial injury and the progression of ischemic cardiomyopathy. Front Physiol. 2014;5:132 pubmed publisher

Donnelly J, Engevik A, Feng R, Xiao C, Boivin G, Li J, et al. Mesenchymal stem cells induce epithelial proliferation within the inflamed stomach. Am J Physiol Gastrointest Liver Physiol. 2014;306:G1075-88 pubmed publisher

Petry F, Pelletier J, Bretteville A, Morin F, Calon F, Hébert S, et al. Specificity of anti-tau antibodies when analyzing mice models of Alzheimer's disease: problems and solutions. PLoS ONE. 2014;9:e94251 pubmed publisher

Huber S, Valente S, Chaimbault P, Schohn H. Evaluation of ?2-pioglitazone, an analogue of pioglitazone, on colon cancer cell survival: Evidence of drug treatment association with autophagy and activation of the Nrf2/Keap1 pathway. Int J Oncol. 2014;45:426-38 pubmed publisher

Ge D, Zhang Q, Zabaleta J, Zhang Q, Liu S, Reiser B, et al. Doublecortin may play a role in defining chondrocyte phenotype. Int J Mol Sci. 2014;15:6941-60 pubmed publisher

Renard G, Sotomayor Zárate R, Blanco E, Gysling K. Withdrawal from chronic amphetamine reduces dopamine transmission in the rat lateral septum. J Neurosci Res. 2014;92:937-43 pubmed publisher

Jabłonowska E, Wojcik K, Szymanska B, Omulecka A, Cwiklinska H, Piekarska A. Hepatic HMOX1 expression positively correlates with Bach-1 and miR-122 in patients with HCV mono and HIV/HCV coinfection. PLoS ONE. 2014;9:e95564 pubmed publisher

Savolainen M, Richie C, Harvey B, Mannisto P, Maguire Zeiss K, Myöhänen T. The beneficial effect of a prolyl oligopeptidase inhibitor, KYP-2047, on alpha-synuclein clearance and autophagy in A30P transgenic mouse. Neurobiol Dis. 2014;68:1-15 pubmed publisher

Lake R, Boetefuer E, Tsai P, Jeong J, Choi I, Won K, et al. The sequence-specific transcription factor c-Jun targets Cockayne syndrome protein B to regulate transcription and chromatin structure. PLoS Genet. 2014;10:e1004284 pubmed publisher

Mattox T, Young M, Rubel C, Spaniel C, Rodriguez J, Grevengoed T, et al. MuRF1 activity is present in cardiac mitochondria and regulates reactive oxygen species production in vivo. J Bioenerg Biomembr. 2014;46:173-87 pubmed publisher

Orecchini E, Doria M, Michienzi A, Giuliani E, Vassena L, Ciafrè S, et al. The HIV-1 Tat protein modulates CD4 expression in human T cells through the induction of miR-222. RNA Biol. 2014;11:334-8 pubmed publisher

Branca C, Sarnico I, Ruotolo R, Lanzillotta A, Viscomi A, Benarese M, et al. Pharmacological targeting of the ?-amyloid precursor protein intracellular domain. Sci Rep. 2014;4:4618 pubmed publisher

Myers S, Andres K, Hagg T, Whittemore S. CD36 deletion improves recovery from spinal cord injury. Exp Neurol. 2014;256:25-38 pubmed publisher

Zhang Z, Dong Z, Lauxen I, Filho M, Nor J. Endothelial cell-secreted EGF induces epithelial to mesenchymal transition and endows head and neck cancer cells with stem-like phenotype. Cancer Res. 2014;74:2869-81 pubmed publisher

Hergueta Redondo M, Sarrió D, Molina Crespo Ã, Megias D, Mota A, Rojo Sebastián A, et al. Gasdermin-B promotes invasion and metastasis in breast cancer cells. PLoS ONE. 2014;9:e90099 pubmed publisher

Mohni K, Kavanaugh G, Cortez D. ATR pathway inhibition is synthetically lethal in cancer cells with ERCC1 deficiency. Cancer Res. 2014;74:2835-45 pubmed publisher

Wang L, Wang J, Qu T, Zhang Y, Shen Y. Reversible acetylation of Lin28 mediated by PCAF and SIRT1. Biochim Biophys Acta. 2014;1843:1188-95 pubmed publisher

Hertz R, Ben Lulu S, Shahi P, Trebicz Geffen M, Benhar M, Ankri S. Proteomic identification of S-nitrosylated proteins in the parasite Entamoeba histolytica by resin-assisted capture: insights into the regulation of the Gal/GalNAc lectin by nitric oxide. PLoS ONE. 2014;9:e91518 pubmed publisher

Fusella F, Ferretti R, Recupero D, Rocca S, Di Savino A, Tornillo G, et al. Morgana acts as a proto-oncogene through inhibition of a ROCK-PTEN pathway. J Pathol. 2014;234:152-63 pubmed publisher

Kurihara T, Sakurai E, Toyomoto M, Kii I, Kawamoto D, Asada T, et al. Alleviation of behavioral hypersensitivity in mouse models of inflammatory pain with two structurally different casein kinase 1 (CK1) inhibitors. Mol Pain. 2014;10:17 pubmed publisher

Eyles D, Liu P, Josh P, Cui X. Intracellular distribution of the vitamin D receptor in the brain: comparison with classic target tissues and redistribution with development. Neuroscience. 2014;268:1-9 pubmed publisher

Maze I, Chaudhury D, Dietz D, von Schimmelmann M, Kennedy P, Lobo M, et al. G9a influences neuronal subtype specification in striatum. Nat Neurosci. 2014;17:533-9 pubmed publisher

Reese C, Perry B, Heywood J, Bonner M, Visconti R, Lee R, et al. Caveolin-1 deficiency may predispose African Americans to systemic sclerosis-related interstitial lung disease. Arthritis Rheumatol. 2014;66:1909-19 pubmed publisher

Azzarelli R, Pacary E, Garg R, Garcez P, van den Berg D, Riou P, et al. An antagonistic interaction between PlexinB2 and Rnd3 controls RhoA activity and cortical neuron migration. Nat Commun. 2014;5:3405 pubmed publisher

Islam M, Jones S, Macluskey M, Ellis I. Is there a pAkt between VEGF and oral cancer cell migration?. Cell Signal. 2014;26:1294-302 pubmed publisher

Tabuchi Y, Wada S, Ikegame M, Kariya A, Furusawa Y, Hoshi N, et al. Development of oral epithelial cell line ROE2 with differentiation potential from transgenic rats harboring temperature-sensitive simian virus40 large T-antigen gene. Exp Anim. 2014;63:31-44 pubmed

Itesako T, Seki N, Yoshino H, Chiyomaru T, Yamasaki T, Hidaka H, et al. The microRNA expression signature of bladder cancer by deep sequencing: the functional significance of the miR-195/497 cluster. PLoS ONE. 2014;9:e84311 pubmed publisher

Liu F, Liu T, Kung F. FKBP12 regulates the localization and processing of amyloid precursor protein in human cell lines. J Biosci. 2014;39:85-95 pubmed

Megison M, Gillory L, Stewart J, Nabers H, Mroczek Musulman E, Waters A, et al. Preclinical evaluation of engineered oncolytic herpes simplex virus for the treatment of pediatric solid tumors. PLoS ONE. 2014;9:e86843 pubmed publisher

Morales E, Sakurai R, Husain S, Paek D, Gong M, Ibe B, et al. Nebulized PPAR? agonists: a novel approach to augment neonatal lung maturation and injury repair in rats. Pediatr Res. 2014;75:631-40 pubmed publisher

Megison M, Gillory L, Stewart J, Nabers H, Mrozcek Musulman E, Beierle E. FAK inhibition abrogates the malignant phenotype in aggressive pediatric renal tumors. Mol Cancer Res. 2014;12:514-26 pubmed publisher

Hui E, Vale R. In vitro membrane reconstitution of the T-cell receptor proximal signaling network. Nat Struct Mol Biol. 2014;21:133-42 pubmed publisher

Siddesha J, Valente A, Yoshida T, Sakamuri S, Delafontaine P, Iba H, et al. Docosahexaenoic acid reverses angiotensin II-induced RECK suppression and cardiac fibroblast migration. Cell Signal. 2014;26:933-41 pubmed publisher

Dorval V, Mandemakers W, Jolivette F, Coudert L, Mazroui R, De Strooper B, et al. Gene and MicroRNA transcriptome analysis of Parkinson's related LRRK2 mouse models. PLoS ONE. 2014;9:e85510 pubmed publisher

Mei W, Dong C, Hui C, Bin L, Fenggen Y, Jingjing S, et al. Gambogenic acid kills lung cancer cells through aberrant autophagy. PLoS ONE. 2014;9:e83604 pubmed publisher

Locke M, Toth J, Petroski M. Lys11- and Lys48-linked ubiquitin chains interact with p97 during endoplasmic-reticulum-associated degradation. Biochem J. 2014;459:205-16 pubmed publisher

Szutorisz H, DiNieri J, Sweet E, Egervári G, Michaelides M, Carter J, et al. Parental THC exposure leads to compulsive heroin-seeking and altered striatal synaptic plasticity in the subsequent generation. Neuropsychopharmacology. 2014;39:1315-23 pubmed publisher

Tomblin J, Salisbury T. Insulin like growth factor 2 regulation of aryl hydrocarbon receptor in MCF-7 breast cancer cells. Biochem Biophys Res Commun. 2014;443:1092-6 pubmed publisher

Nolly M, Caldiz C, Yeves A, Villa Abrille M, Morgan P, Amado Mondaca N, et al. The signaling pathway for aldosterone-induced mitochondrial production of superoxide anion in the myocardium. J Mol Cell Cardiol. 2014;67:60-8 pubmed publisher

Ching J, Lobanova L, Loewen M. Secreted hCLCA1 is a signaling molecule that activates airway macrophages. PLoS ONE. 2013;8:e83130 pubmed publisher

Park K, Franciosi S, Leavitt B. Postnatal muscle modification by myogenic factors modulates neuropathology and survival in an ALS mouse model. Nat Commun. 2013;4:2906 pubmed publisher

Moritz C, Marz S, Reiss R, Schulenborg T, Friauf E. Epicocconone staining: a powerful loading control for Western blots. Proteomics. 2014;14:162-8 pubmed publisher

Baas R, Lelieveld D, van Teeffelen H, Lijnzaad P, Castelijns B, van Schaik F, et al. A novel microscopy-based high-throughput screening method to identify proteins that regulate global histone modification levels. J Biomol Screen. 2014;19:287-96 pubmed publisher

Datta S, Parajuli N, Tymoszuk P, Ottina E, Parson W, Sgonc R, et al. Replenishment of the B cell compartment after doxorubicin-induced hematopoietic toxicity is facilitated by STAT1. J Leukoc Biol. 2014;95:853-66 pubmed publisher

McDonald C, Wallace D, Ostini L, Subramaniam V. Parenteral vs. oral iron: influence on hepcidin signaling pathways through analysis of Hfe/Tfr2-null mice. Am J Physiol Gastrointest Liver Physiol. 2014;306:G132-9 pubmed publisher

Johnson J, Nishioka M, Chakir J, Risse P, Almaghlouth I, Bazarbashi A, et al. IL-22 contributes to TGF-?1-mediated epithelial-mesenchymal transition in asthmatic bronchial epithelial cells. Respir Res. 2013;14:118 pubmed publisher

Siddesha J, Valente A, Sakamuri S, Gardner J, Delafontaine P, Noda M, et al. Acetylsalicylic acid inhibits IL-18-induced cardiac fibroblast migration through the induction of RECK. J Cell Physiol. 2014;229:845-55 pubmed publisher

Webster M, Fan C. c-MET regulates myoblast motility and myocyte fusion during adult skeletal muscle regeneration. PLoS ONE. 2013;8:e81757 pubmed publisher

Jules J, Maiguel D, Hudson B. Alternative splicing of the RAGE cytoplasmic domain regulates cell signaling and function. PLoS ONE. 2013;8:e78267 pubmed publisher

Hart D, Nilges M, Pollard K, Lynn T, Patsos O, Shiel C, et al. Activation of the G-protein coupled receptor 30 (GPR30) has different effects on anxiety in male and female mice. Steroids. 2014;81:49-56 pubmed publisher

Huang T, Shao Q, Barr K, Simek J, Fishman G, Laird D. Myogenic bladder defects in mouse models of human oculodentodigital dysplasia. Biochem J. 2014;457:441-9 pubmed publisher

Janusz A, Milek J, Perycz M, Pacini L, Bagni C, Kaczmarek L, et al. The Fragile X mental retardation protein regulates matrix metalloproteinase 9 mRNA at synapses. J Neurosci. 2013;33:18234-41 pubmed publisher

Listerman I, Gazzaniga F, Blackburn E. An investigation of the effects of the core protein telomerase reverse transcriptase on Wnt signaling in breast cancer cells. Mol Cell Biol. 2014;34:280-9 pubmed publisher

Leibovich Rivkin T, Buganim Y, Solomon H, Meshel T, Rotter V, Ben Baruch A. Tumor-promoting circuits that regulate a cancer-related chemokine cluster: dominance of inflammatory mediators over oncogenic alterations. Cancers (Basel). 2012;4:55-76 pubmed publisher

Rizqiawan A, Tobiume K, Okui G, Yamamoto K, Shigeishi H, Ono S, et al. Autocrine galectin-1 promotes collective cell migration of squamous cell carcinoma cells through up-regulation of distinct integrins. Biochem Biophys Res Commun. 2013;441:904-10 pubmed publisher

Donnelly J, Engevik A, Engevik M, Schumacher M, Xiao C, Yang L, et al. Gastritis promotes an activated bone marrow-derived mesenchymal stem cell with a phenotype reminiscent of a cancer-promoting cell. Dig Dis Sci. 2014;59:569-82 pubmed publisher

Shin M, Jung W, Kim H, Roh S, Kwak C, Kim C, et al. The ganglioside GQ1b regulates BDNF expression via the NMDA receptor signaling pathway. Neuropharmacology. 2014;77:414-21 pubmed publisher

Geering B, Stoeckle C, Rozman S, Oberson K, Benarafa C, Simon H. DAPK2 positively regulates motility of neutrophils and eosinophils in response to intermediary chemoattractants. J Leukoc Biol. 2014;95:293-303 pubmed publisher

Forrester A, Elias M, Woodward E, Graham M, Williams F, Reynolds N. Induction of a chloracne phenotype in an epidermal equivalent model by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is dependent on aryl hydrocarbon receptor activation and is not reproduced by aryl hydrocarbon receptor knock down. J Dermatol Sci. 2014;73:10-22 pubmed publisher

Queirós A, Eschen C, Fliegner D, Kararigas G, Dworatzek E, Westphal C, et al. Sex- and estrogen-dependent regulation of a miRNA network in the healthy and hypertrophied heart. Int J Cardiol. 2013;169:331-8 pubmed publisher

Chicoine L, Rodino Klapac L, Shao G, Xu R, Bremer W, Camboni M, et al. Vascular delivery of rAAVrh74.MCK.GALGT2 to the gastrocnemius muscle of the rhesus macaque stimulates the expression of dystrophin and laminin ?2 surrogates. Mol Ther. 2014;22:713-24 pubmed publisher

Hoffman Y, Bublik D, Pilpel Y, Oren M. miR-661 downregulates both Mdm2 and Mdm4 to activate p53. Cell Death Differ. 2014;21:302-9 pubmed publisher

Shetty A, Sytnyk V, Leshchyns ka I, Puchkov D, Haucke V, Schachner M. The neural cell adhesion molecule promotes maturation of the presynaptic endocytotic machinery by switching synaptic vesicle recycling from adaptor protein 3 (AP-3)- to AP-2-dependent mechanisms. J Neurosci. 2013;33:16828-45 pubmed publisher

Kim T, Kang Y, Park Z, Kim Y, Hong S, Oh S, et al. SH3RF2 functions as an oncogene by mediating PAK4 protein stability. Carcinogenesis. 2014;35:624-34 pubmed publisher

Lorion C, Faye C, Maret B, Trimaille T, Regnier T, Sommer P, et al. Biosynthetic support based on dendritic poly(L-lysine) improves human skin fibroblasts attachment. J Biomater Sci Polym Ed. 2014;25:136-49 pubmed publisher

Hsu S, Wang B, Kutay H, Bid H, Shreve J, Zhang X, et al. Hepatic loss of miR-122 predisposes mice to hepatobiliary cyst and hepatocellular carcinoma upon diethylnitrosamine exposure. Am J Pathol. 2013;183:1719-1730 pubmed publisher

Steyn F, Lee K, Fogarty M, Veldhuis J, McCombe P, Bellingham M, et al. Growth hormone secretion is correlated with neuromuscular innervation rather than motor neuron number in early-symptomatic male amyotrophic lateral sclerosis mice. Endocrinology. 2013;154:4695-706 pubmed publisher

Chen Y, Huang W, Chang S, Chang K, Kao S, Lo J, et al. Enhanced filopodium formation and stem-like phenotypes in a novel metastatic head and neck cancer cell model. Oncol Rep. 2013;30:2829-37 pubmed publisher

Lan K, Chen Y, Chang C, Chang Y, Lin H, Huang K, et al. Up-regulation of SOX9 in sertoli cells from testiculopathic patients accounts for increasing anti-mullerian hormone expression via impaired androgen receptor signaling. PLoS ONE. 2013;8:e76303 pubmed publisher

Reyes Aguirre L, Ferraro S, Quintero H, Sánchez Serrano S, Gomez Montalvo A, Lamas M. Glutamate-induced epigenetic and morphological changes allow rat Müller cell dedifferentiation but not further acquisition of a photoreceptor phenotype. Neuroscience. 2013;254:347-60 pubmed publisher

Chen L, Miao Y, Chen L, Jin P, Zha Y, Chai Y, et al. The role of elevated autophagy on the synaptic plasticity impairment caused by CdSe/ZnS quantum dots. Biomaterials. 2013;34:10172-81 pubmed publisher

Botchkina G, Zuniga E, Rowehl R, Park R, Bhalla R, Bialkowska A, et al. Prostate cancer stem cell-targeted efficacy of a new-generation taxoid, SBT-1214 and novel polyenolic zinc-binding curcuminoid, CMC2.24. PLoS ONE. 2013;8:e69884 pubmed publisher

Zhou Z, Karlsson C, Liang T, Xiong W, Kimura M, Tapocik J, et al. Loss of metabotropic glutamate receptor 2 escalates alcohol consumption. Proc Natl Acad Sci U S A. 2013;110:16963-8 pubmed publisher

Czeisler C, Mikawa T. Microtubules coordinate VEGFR2 signaling and sorting. PLoS ONE. 2013;8:e75833 pubmed publisher

Sachs B, Salahi A, Caron M. Congenital brain serotonin deficiency leads to reduced ethanol sensitivity and increased ethanol consumption in mice. Neuropharmacology. 2014;77:177-84 pubmed publisher

Grasberger H, Chang L, Shih W, Presson A, Sayuk G, Newberry R, et al. Identification of a functional TPH1 polymorphism associated with irritable bowel syndrome bowel habit subtypes. Am J Gastroenterol. 2013;108:1766-74 pubmed publisher

Svendsen A, Winge S, Zimmermann M, Lindvig A, Warzecha C, Sajid W, et al. Down-regulation of cyclin G2 by insulin, IGF-I (insulin-like growth factor 1) and X10 (AspB10 insulin): role in mitogenesis. Biochem J. 2014;457:69-77 pubmed publisher

Vassena L, Giuliani E, Matusali G, Cohen r, Doria M. The human immunodeficiency virus type 1 Vpr protein upregulates PVR via activation of the ATR-mediated DNA damage response pathway. J Gen Virol. 2013;94:2664-9 pubmed publisher

Araki K, Iemura S, Kamiya Y, Ron D, Kato K, Natsume T, et al. Ero1-α and PDIs constitute a hierarchical electron transfer network of endoplasmic reticulum oxidoreductases. J Cell Biol. 2013;202:861-74 pubmed publisher

Harris J, Richards R, Chow C, Lee S, Kim M, Buck M, et al. BMCC1 is an AP-2 associated endosomal protein in prostate cancer cells. PLoS ONE. 2013;8:e73880 pubmed publisher

Ge D, Dauchy R, Liu S, Zhang Q, Mao L, Dauchy E, et al. Insulin and IGF1 enhance IL-17-induced chemokine expression through a GSK3B-dependent mechanism: a new target for melatonin's anti-inflammatory action. J Pineal Res. 2013;55:377-87 pubmed publisher

Yoshino H, Enokida H, Itesako T, Kojima S, Kinoshita T, Tatarano S, et al. Tumor-suppressive microRNA-143/145 cluster targets hexokinase-2 in renal cell carcinoma. Cancer Sci. 2013;104:1567-74 pubmed publisher

Wilde J, Erdmann M, Mertens M, Eiselt G, Schmidt M. Aromatase activity induction in human adipose fibroblasts by retinoic acids via retinoic acid receptor ?. J Mol Endocrinol. 2013;51:247-60 pubmed publisher

Camboni M, Wang C, Miranda C, Yoon J, Xu R, Zygmunt D, et al. Active and passive immunization strategies based on the SDPM1 peptide demonstrate pre-clinical efficacy in the APPswePSEN1dE9 mouse model for Alzheimer's disease. Neurobiol Dis. 2014;62:31-43 pubmed publisher

Liu Y, Käch A, Ziegler U, Ong A, Wallace D, Arcaro A, et al. The role of phospholipase D in modulating the MTOR signaling pathway in polycystic kidney disease. PLoS ONE. 2013;8:e73173 pubmed publisher

Meitzen J, Luoma J, Boulware M, Hedges V, Peterson B, Tuomela K, et al. Palmitoylation of estrogen receptors is essential for neuronal membrane signaling. Endocrinology. 2013;154:4293-304 pubmed publisher

Bezrookove V, De Semir D, Nosrati M, Tong S, Wu C, Thummala S, et al. Prognostic impact of PHIP copy number in melanoma: linkage to ulceration. J Invest Dermatol. 2014;134:783-790 pubmed publisher

Boi M, Rinaldi A, Kwee I, Bonetti P, Todaro M, Tabbò F, et al. PRDM1/BLIMP1 is commonly inactivated in anaplastic large T-cell lymphoma. Blood. 2013;122:2683-93 pubmed publisher

Kim S, Jackson Boeters L, Darling M, Rieder M, Hamilton D. Nifedipine induces periostin expression in gingival fibroblasts through TGF-beta. J Dent Res. 2013;92:1022-8 pubmed publisher

Jiang H, Lu X, Shimada M, Dou Y, Tang Z, Roeder R. Regulation of transcription by the MLL2 complex and MLL complex-associated AKAP95. Nat Struct Mol Biol. 2013;20:1156-63 pubmed publisher

Ramirez C, Pham K, Franco M, Chwa M, Limb A, Kuppermann B, et al. Hydroquinone induces oxidative and mitochondrial damage to human retinal Müller cells (MIO-M1). Neurotoxicology. 2013;39:102-8 pubmed publisher

Harada S, Nakamoto K, Tokuyama S. The involvement of midbrain astrocyte in the development of morphine tolerance. Life Sci. 2013;93:573-8 pubmed publisher

Haflidadóttir B, Larne O, Martin M, Persson M, Edsjö A, Bjartell A, et al. Upregulation of miR-96 enhances cellular proliferation of prostate cancer cells through FOXO1. PLoS ONE. 2013;8:e72400 pubmed publisher

Bhattacharya A, Li Y, Shi Y, Zhang Y. Enhanced inhibition of urinary bladder cancer growth and muscle invasion by allyl isothiocyanate and celecoxib in combination. Carcinogenesis. 2013;34:2593-9 pubmed publisher

Benz P, Merkel C, Offner K, Abeßer M, Ullrich M, Fischer T, et al. Mena/VASP and ?II-Spectrin complexes regulate cytoplasmic actin networks in cardiomyocytes and protect from conduction abnormalities and dilated cardiomyopathy. Cell Commun Signal. 2013;11:56 pubmed publisher

Neutelings T, Lambert C, Nusgens B, Colige A. Effects of mild cold shock (25°C) followed by warming up at 37°C on the cellular stress response. PLoS ONE. 2013;8:e69687 pubmed publisher

Ishikado A, Morino K, Nishio Y, Nakagawa F, Mukose A, Sono Y, et al. 4-Hydroxy hexenal derived from docosahexaenoic acid protects endothelial cells via Nrf2 activation. PLoS ONE. 2013;8:e69415 pubmed publisher

Staffend N, Hedges V, Chemel B, Watts V, Meisel R. Cell-type specific increases in female hamster nucleus accumbens spine density following female sexual experience. Brain Struct Funct. 2014;219:2071-81 pubmed publisher

Papacleovoulou G, Abu Hayyeh S, Nikolopoulou E, Briz O, Owen B, Nikolova V, et al. Maternal cholestasis during pregnancy programs metabolic disease in offspring. J Clin Invest. 2013;123:3172-81 pubmed publisher

Bonetti P, Testoni M, Scandurra M, Ponzoni M, Piva R, Mensah A, et al. Deregulation of ETS1 and FLI1 contributes to the pathogenesis of diffuse large B-cell lymphoma. Blood. 2013;122:2233-41 pubmed publisher

Hagman Z, Haflidadóttir B, Ansari M, Persson M, Bjartell A, Edsjö A, et al. The tumour suppressor miR-34c targets MET in prostate cancer cells. Br J Cancer. 2013;109:1271-8 pubmed publisher

Andrianifahanana M, Wilkes M, Gupta S, Rahimi R, Repellin C, Edens M, et al. Profibrotic TGF? responses require the cooperative action of PDGF and ErbB receptor tyrosine kinases. FASEB J. 2013;27:4444-54 pubmed publisher

Rehan V, Liu J, Sakurai R, Torday J. Perinatal nicotine-induced transgenerational asthma. Am J Physiol Lung Cell Mol Physiol. 2013;305:L501-7 pubmed publisher

Kullmann M, Grubbauer C, Goetsch K, Jakel H, Podmirseg S, Trockenbacher A, et al. The p27-Skp2 axis mediates glucocorticoid-induced cell cycle arrest in T-lymphoma cells. Cell Cycle. 2013;12:2625-35 pubmed publisher

Chen J, Doroudi M, Cheung J, Grozier A, Schwartz Z, Boyan B. Plasma membrane Pdia3 and VDR interact to elicit rapid responses to 1?,25(OH)(2)D(3). Cell Signal. 2013;25:2362-73 pubmed publisher

Yamasaki T, Seki N, Yoshino H, Itesako T, Yamada Y, Tatarano S, et al. Tumor-suppressive microRNA-1291 directly regulates glucose transporter 1 in renal cell carcinoma. Cancer Sci. 2013;104:1411-9 pubmed publisher

Banday A, Lokhandwala M. Transcription factor Nrf2 protects renal dopamine D1 receptor function during oxidative stress. Hypertension. 2013;62:512-7 pubmed publisher

Li C, Ito H, Fujita K, Shiwaku H, Qi Y, Tagawa K, et al. Sox2 transcriptionally regulates PQBP1, an intellectual disability-microcephaly causative gene, in neural stem progenitor cells. PLoS ONE. 2013;8:e68627 pubmed publisher

Truong D, Brabant D, Bashkurov M, Wan L, Braun V, Heo W, et al. Formin-mediated actin polymerization promotes Salmonella invasion. Cell Microbiol. 2013;15:2051-63 pubmed publisher

Lobert S, Graichen M, Morris K. Coordinated regulation of ?-tubulin isotypes and epithelial-to-mesenchymal transition protein ZEB1 in breast cancer cells. Biochemistry. 2013;52:5482-90 pubmed publisher

Suryavanshi N, Ridley A. Determining Rho GTPase activity by an affinity-precipitation assay. Methods Mol Biol. 2013;1046:191-202 pubmed publisher

Dreier B, Thomasy S, Mendonsa R, Raghunathan V, Russell P, Murphy C. Substratum compliance modulates corneal fibroblast to myofibroblast transformation. Invest Ophthalmol Vis Sci. 2013;54:5901-7 pubmed publisher

Ju Y, Yu A, Sun X, Wu D, Zhang H. Glucosamine, a naturally occurring amino monosaccharide, inhibits A549 and H446 cell proliferation by blocking G1/S transition. Mol Med Rep. 2013;8:794-8 pubmed publisher

Martínez Alvarez L, Piña Vázquez C, Zarco W, Padilla Noriega L. The shift from low to high non-structural protein 1 expression in rotavirus-infected MA-104 cells. Mem Inst Oswaldo Cruz. 2013;108:421-8 pubmed publisher

Hagl S, Kocher A, Schiborr C, Eckert S, Ciobanu I, Birringer M, et al. Rice bran extract protects from mitochondrial dysfunction in guinea pig brains. Pharmacol Res. 2013;76:17-27 pubmed publisher

de la Cueva A, Ramirez de Molina A, Alvarez Ayerza N, Ramos M, Cebrian A, del Pulgar T, et al. Combined 5-FU and ChoK? inhibitors as a new alternative therapy of colorectal cancer: evidence in human tumor-derived cell lines and mouse xenografts. PLoS ONE. 2013;8:e64961 pubmed publisher

Tashiro E, Zako T, Muto H, Itoo Y, Sörgjerd K, Terada N, et al. Prefoldin protects neuronal cells from polyglutamine toxicity by preventing aggregation formation. J Biol Chem. 2013;288:19958-72 pubmed publisher

Glukhova V, Tomazela D, Findlay G, Monnat R, MacCoss M. Rapid assessment of RNAi-mediated protein depletion by selected reaction monitoring mass spectrometry. J Proteome Res. 2013;12:3246-54 pubmed publisher

Pacurari M, Addison J, Bondalapati N, Wan Y, Luo D, Qian Y, et al. The microRNA-200 family targets multiple non-small cell lung cancer prognostic markers in H1299 cells and BEAS-2B cells. Int J Oncol. 2013;43:548-60 pubmed publisher

Turczynska K, Bhattachariya A, Säll J, Göransson O, Swärd K, Hellstrand P, et al. Stretch-sensitive down-regulation of the miR-144/451 cluster in vascular smooth muscle and its role in AMP-activated protein kinase signaling. PLoS ONE. 2013;8:e65135 pubmed publisher

Gholizadeh S, Sun N, De Jaeger X, Bechard M, Coolen L, Laviolette S. Early versus late-phase consolidation of opiate reward memories requires distinct molecular and temporal mechanisms in the amygdala-prefrontal cortical pathway. PLoS ONE. 2013;8:e63612 pubmed publisher

Shu X, Li L, Ji M, Cheng Y, Ying J, Fan Y, et al. FEZF2, a novel 3p14 tumor suppressor gene, represses oncogene EZH2 and MDM2 expression and is frequently methylated in nasopharyngeal carcinoma. Carcinogenesis. 2013;34:1984-93 pubmed publisher

Fan W, Stirewalt D, Radich J, Zhao L. Comparison of Two Methods for Detecting Alternative Splice Variants Using GeneChip(®) Exon Arrays. Int J Biomed Sci. 2011;7:172-80 pubmed

Gillis J, Selth L, Centenera M, Townley S, Sun S, Plymate S, et al. Constitutively-active androgen receptor variants function independently of the HSP90 chaperone but do not confer resistance to HSP90 inhibitors. Oncotarget. 2013;4:691-704 pubmed

Sachs B, Rodriguiz R, Siesser W, Kenan A, Royer E, Jacobsen J, et al. The effects of brain serotonin deficiency on behavioural disinhibition and anxiety-like behaviour following mild early life stress. Int J Neuropsychopharmacol. 2013;16:2081-94 pubmed publisher

Shao L, Oshima S, Duong B, Advincula R, Barrera J, Malynn B, et al. A20 restricts wnt signaling in intestinal epithelial cells and suppresses colon carcinogenesis. PLoS ONE. 2013;8:e62223 pubmed publisher

Arima N, Uchida Y, Yu R, Nakayama K, Nishina H. Acetylcholine receptors regulate gene expression that is essential for primitive streak formation in murine embryoid bodies. Biochem Biophys Res Commun. 2013;435:447-53 pubmed publisher

Rodrígues Díez R, Rodrigues Díez R, Rayego Mateos S, Suarez Alvarez B, Lavoz C, Stark Aroeira L, et al. The C-terminal module IV of connective tissue growth factor is a novel immune modulator of the Th17 response. Lab Invest. 2013;93:812-24 pubmed publisher

Ludwig K, Tse E, Wang J. Colon cancer cells adopt an invasive phenotype without mesenchymal transition in 3-D but not 2-D culture upon combined stimulation with EGF and crypt growth factors. BMC Cancer. 2013;13:221 pubmed publisher

Dalvai M, Fleury L, Bellucci L, Kocanova S, Bystricky K. TIP48/Reptin and H2A.Z requirement for initiating chromatin remodeling in estrogen-activated transcription. PLoS Genet. 2013;9:e1003387 pubmed publisher

Doi H, Adachi H, Katsuno M, Minamiyama M, Matsumoto S, Kondo N, et al. p62/SQSTM1 differentially removes the toxic mutant androgen receptor via autophagy and inclusion formation in a spinal and bulbar muscular atrophy mouse model. J Neurosci. 2013;33:7710-27 pubmed publisher

Carroll C, O Connor D, Steinmeyer R, Del Mundo J, McMullan D, Whitt J, et al. The influence of acute resistance exercise on cyclooxygenase-1 and -2 activity and protein levels in human skeletal muscle. Am J Physiol Regul Integr Comp Physiol. 2013;305:R24-30 pubmed publisher

Madar S, Harel E, Goldstein I, Stein Y, Kogan Sakin I, Kamer I, et al. Mutant p53 attenuates the anti-tumorigenic activity of fibroblasts-secreted interferon beta. PLoS ONE. 2013;8:e61353 pubmed publisher

Jensen L, Farook M, Reiter L. Proteomic profiling in Drosophila reveals potential Dube3a regulation of the actin cytoskeleton and neuronal homeostasis. PLoS ONE. 2013;8:e61952 pubmed publisher

Meneghello C, Ousghir B, Rastrelli M, Anesi L, Sommariva A, Montesco M, et al. Nuclear GSK-3? segregation in desmoid-type fibromatosis. Histopathology. 2013;62:1098-108 pubmed publisher

Sedek M, Strous G. SUMOylation is a regulator of the translocation of Jak2 between nucleus and cytosol. Biochem J. 2013;453:231-9 pubmed publisher

Hagman Z, Haflidadóttir B, Ceder J, Larne O, Bjartell A, Lilja H, et al. miR-205 negatively regulates the androgen receptor and is associated with adverse outcome of prostate cancer patients. Br J Cancer. 2013;108:1668-76 pubmed publisher

Adler J, Heller B, Bringman L, Ranahan W, Cocklin R, Goebl M, et al. Amot130 adapts atrophin-1 interacting protein 4 to inhibit yes-associated protein signaling and cell growth. J Biol Chem. 2013;288:15181-93 pubmed publisher

Kersseboom S, Kremers G, Friesema E, Visser W, Klootwijk W, Peeters R, et al. Mutations in MCT8 in patients with Allan-Herndon-Dudley-syndrome affecting its cellular distribution. Mol Endocrinol. 2013;27:801-13 pubmed publisher

Lima de Souza E, Groeneweg S, Visser W, Peeters R, Visser T. Importance of cysteine residues in the thyroid hormone transporter MCT8. Endocrinology. 2013;154:1948-55 pubmed publisher

de Weille J, Fabre C, Gaven C, Bakalara N. Similar pyruvate kinase modifications in glioblastoma cells by 7?-hydroxycholesterol and glutamine withdrawal. Biochem Pharmacol. 2013;86:161-7 pubmed publisher

Elfrink H, Zwart R, Baas F, Scheper W. Inhibition of endoplasmic reticulum associated degradation reduces endoplasmic reticulum stress and alters lysosomal morphology and distribution. Mol Cells. 2013;35:291-7 pubmed publisher

Arimoto J, Wong A, Rozovsky I, Lin S, Morgan T, Finch C. Age increase of estrogen receptor-? (ER?) in cortical astrocytes impairs neurotrophic support in male and female rats. Endocrinology. 2013;154:2101-13 pubmed publisher

Feng L, Fong K, Wang J, Wang W, Chen J. RIF1 counteracts BRCA1-mediated end resection during DNA repair. J Biol Chem. 2013;288:11135-43 pubmed publisher

Gold J, Martini J, Hullmann J, Gao E, Chuprun J, Lee L, et al. Nuclear translocation of cardiac G protein-Coupled Receptor kinase 5 downstream of select Gq-activating hypertrophic ligands is a calmodulin-dependent process. PLoS ONE. 2013;8:e57324 pubmed publisher

Zaade D, Schmitz J, Benke E, Klare S, Seidel K, Kirsch S, et al. Distinct signal transduction pathways downstream of the (P)RR revealed by microarray and ChIP-chip analyses. PLoS ONE. 2013;8:e57674 pubmed publisher

Nam H, Hinton D, Kang N, Kim T, Lee M, Oliveros A, et al. Adenosine transporter ENT1 regulates the acquisition of goal-directed behavior and ethanol drinking through A2A receptor in the dorsomedial striatum. J Neurosci. 2013;33:4329-38 pubmed publisher

Maubach G, Sokolova O, Wolfien M, Rothkötter H, Naumann M. Ca2+/calmodulin-dependent kinase II contributes to inhibitor of nuclear factor-kappa B kinase complex activation in Helicobacter pylori infection. Int J Cancer. 2013;133:1507-12 pubmed publisher

Yamasaki T, Seki N, Yoshino H, Itesako T, Hidaka H, Yamada Y, et al. MicroRNA-218 inhibits cell migration and invasion in renal cell carcinoma through targeting caveolin-2 involved in focal adhesion pathway. J Urol. 2013;190:1059-68 pubmed publisher

Liu F, Xue Z, Deng S, Kun X, Luo X, Patrylo P, et al. γ-secretase binding sites in aged and Alzheimer's disease human cerebrum: the choroid plexus as a putative origin of CSF Aβ. Eur J Neurosci. 2013;37:1714-25 pubmed publisher

Eckert G, Schiborr C, Hagl S, Abdel Kader R, Muller W, Rimbach G, et al. Curcumin prevents mitochondrial dysfunction in the brain of the senescence-accelerated mouse-prone 8. Neurochem Int. 2013;62:595-602 pubmed publisher

Molchadsky A, Ezra O, Amendola P, Krantz D, Kogan Sakin I, Buganim Y, et al. p53 is required for brown adipogenic differentiation and has a protective role against diet-induced obesity. Cell Death Differ. 2013;20:774-83 pubmed publisher

Johnson A, Lee J, Harmon A, Morris Z, Wang X, Fratkin J, et al. A mutation in the start codon of ?-crystallin D leads to nuclear cataracts in the Dahl SS/Jr-Ctr strain. Mamm Genome. 2013;24:95-104 pubmed publisher

Nautiyal J, Steel J, Mane M, Oduwole O, Poliandri A, Alexi X, et al. The transcriptional co-factor RIP140 regulates mammary gland development by promoting the generation of key mitogenic signals. Development. 2013;140:1079-89 pubmed publisher

Robinson E, Nandi M, Wilkinson L, Arrowsmith D, Curtis A, Richardson A. Preclinical evaluation of statins as a treatment for ovarian cancer. Gynecol Oncol. 2013;129:417-24 pubmed publisher

Althoff K, Beckers A, Odersky A, Mestdagh P, Köster J, Bray I, et al. MiR-137 functions as a tumor suppressor in neuroblastoma by downregulating KDM1A. Int J Cancer. 2013;133:1064-73 pubmed publisher

Joubert R, Vignaud A, Le M, Moal C, Messaddeq N, Buj Bello A. Site-specific Mtm1 mutagenesis by an AAV-Cre vector reveals that myotubularin is essential in adult muscle. Hum Mol Genet. 2013;22:1856-66 pubmed publisher

Karasinska J, de Haan W, Franciosi S, Ruddle P, Fan J, Kruit J, et al. ABCA1 influences neuroinflammation and neuronal death. Neurobiol Dis. 2013;54:445-55 pubmed publisher

Gomez J, Lewis M, Sebastian V, Serrano P, Luine V. Alcohol administration blocks stress-induced impairments in memory and anxiety, and alters hippocampal neurotransmitter receptor expression in male rats. Horm Behav. 2013;63:659-66 pubmed publisher

Reale M, Webb I, Wang X, Baltazar R, Coolen L, Lehman M. The transcription factor Runx2 is under circadian control in the suprachiasmatic nucleus and functions in the control of rhythmic behavior. PLoS ONE. 2013;8:e54317 pubmed publisher

Weterman M, Barth P, van Spaendonck Zwarts K, Aronica E, Poll The B, Brouwer O, et al. Recessive MYL2 mutations cause infantile type I muscle fibre disease and cardiomyopathy. Brain. 2013;136:282-93 pubmed publisher

Inuzuka T, Inokawa A, Chen C, Kizu K, Narita H, Shibata H, et al. ALG-2-interacting Tubby-like protein superfamily member PLSCR3 is secreted by an exosomal pathway and taken up by recipient cultured cells. Biosci Rep. 2013;33:e00026 pubmed publisher

Bellucci L, Dalvai M, Kocanova S, Moutahir F, Bystricky K. Activation of p21 by HDAC inhibitors requires acetylation of H2A.Z. PLoS ONE. 2013;8:e54102 pubmed publisher

Harper M, van den Bosch M, Hers I, Poole A. Absence of platelet phenotype in mice lacking the motor protein myosin Va. PLoS ONE. 2013;8:e53239 pubmed publisher

Han J, Soletti R, Sadarangani A, Sridevi P, Ramirez M, Eckmann L, et al. Nuclear expression of ?-catenin promotes RB stability and resistance to TNF-induced apoptosis in colon cancer cells. Mol Cancer Res. 2013;11:207-18 pubmed publisher

Shin J, Krey J, Hassan A, Metlagel Z, Tauscher A, Pagana J, et al. Molecular architecture of the chick vestibular hair bundle. Nat Neurosci. 2013;16:365-74 pubmed publisher

Fujii Y, Kishi Y, Gotoh Y. IMP2 regulates differentiation potentials of mouse neocortical neural precursor cells. Genes Cells. 2013;18:79-89 pubmed publisher

Yoneda T, Kameyama K, Esumi K, Daimyo Y, Watanabe M, Hata Y. Developmental and visual input-dependent regulation of the CB1 cannabinoid receptor in the mouse visual cortex. PLoS ONE. 2013;8:e53082 pubmed publisher

Frangini M, Franzolin E, Chemello F, Laveder P, Romualdi C, Bianchi V, et al. Synthesis of mitochondrial DNA precursors during myogenesis, an analysis in purified C2C12 myotubes. J Biol Chem. 2013;288:5624-35 pubmed publisher

Kepp O, Martins I, Menger L, Michaud M, Adjemian S, Sukkurwala A, et al. Quantification of cell cycle-arresting proteins. Methods Mol Biol. 2013;965:121-42 pubmed publisher

Nagasawa A, Yoshimura K, Suzuki R, Mikamo A, Yamashita O, Ikeda Y, et al. Important role of the angiotensin II pathway in producing matrix metalloproteinase-9 in human thoracic aortic aneurysms. J Surg Res. 2013;183:472-7 pubmed publisher

Perrin S, Cremer J, Faucher O, Reynes J, Dellamonica P, Micallef J, et al. HIV protease inhibitors do not cause the accumulation of prelamin A in PBMCs from patients receiving first line therapy: the ANRS EP45 "aging" study. PLoS ONE. 2012;7:e53035 pubmed publisher

Ishikado A, Sono Y, Matsumoto M, Robida Stubbs S, Okuno A, Goto M, et al. Willow bark extract increases antioxidant enzymes and reduces oxidative stress through activation of Nrf2 in vascular endothelial cells and Caenorhabditis elegans. Free Radic Biol Med. 2013;65:1506-1515 pubmed publisher

Matsui H, Yokoyama T, Tanaka C, Sunaga H, Koitabashi N, Takizawa T, et al. Pressure mediated hypertrophy and mechanical stretch up-regulate expression of the long form of leptin receptor (ob-Rb) in rat cardiac myocytes. BMC Cell Biol. 2012;13:37 pubmed publisher

Federzoni E, Humbert M, Valk P, Behre G, Leibundgut E, Torbett B, et al. The actin-binding protein CORO1A is a novel PU.1 (SPI1)- and CEBPA-regulated gene with significantly lower expression in APL and CEBPA-mutated AML patients. Br J Haematol. 2013;160:855-9 pubmed publisher

Coradeghini R, Gioria S, Garcia C, Nativo P, Franchini F, Gilliland D, et al. Size-dependent toxicity and cell interaction mechanisms of gold nanoparticles on mouse fibroblasts. Toxicol Lett. 2013;217:205-16 pubmed publisher

Sumi H, Yabuki M, Iwai K, Morimoto M, Hibino R, Inazuka M, et al. Antitumor activity and pharmacodynamic biomarkers of a novel and orally available small-molecule antagonist of inhibitor of apoptosis proteins. Mol Cancer Ther. 2013;12:230-40 pubmed publisher

Vassoler F, White S, Schmidt H, Sadri Vakili G, Pierce R. Epigenetic inheritance of a cocaine-resistance phenotype. Nat Neurosci. 2013;16:42-7 pubmed publisher

Chu E, Sze S, Cheung H, Liu Q, Ng T, Tong Y. An in vitro and in vivo investigation of the antimetastatic effects of a Chinese medicinal decoction, erxian decoction, on human ovarian cancer models. Integr Cancer Ther. 2013;12:336-46 pubmed publisher

Brody M, Hacker T, Patel J, Feng L, Sadoshima J, Tevosian S, et al. Ablation of the cardiac-specific gene leucine-rich repeat containing 10 (Lrrc10) results in dilated cardiomyopathy. PLoS ONE. 2012;7:e51621 pubmed publisher

Shalginskikh N, Poleshko A, Skalka A, Katz R. Retroviral DNA methylation and epigenetic repression are mediated by the antiviral host protein Daxx. J Virol. 2013;87:2137-50 pubmed publisher

Smith L, Belanger J, Oberbauer A. Fibroblast growth factor receptor 3 effects on proliferation and telomerase activity in sheep growth plate chondrocytes. J Anim Sci Biotechnol. 2012;3:39 pubmed publisher

Moghe S, Jiang F, Miura Y, Cerny R, Tsai M, Furukawa M. The CUL3-KLHL18 ligase regulates mitotic entry and ubiquitylates Aurora-A. Biol Open. 2012;1:82-91 pubmed publisher

Yang L, Li Y, Ding Y, Choi K, Kazim A, Zhang Y. Prolidase directly binds and activates epidermal growth factor receptor and stimulates downstream signaling. J Biol Chem. 2013;288:2365-75 pubmed publisher

Sanchez A, Tripathy D, Luo J, Yin X, Martinez J, Grammas P. Neurovascular unit and the effects of dosage in VEGF toxicity: role for oxidative stress and thrombin. J Alzheimers Dis. 2013;34:281-91 pubmed publisher

Chopra V, Quinti L, Kim J, Vollor L, Narayanan K, Edgerly C, et al. The sirtuin 2 inhibitor AK-7 is neuroprotective in Huntington's disease mouse models. Cell Rep. 2012;2:1492-7 pubmed publisher

Yamada Y, Hidaka H, Seki N, Yoshino H, Yamasaki T, Itesako T, et al. Tumor-suppressive microRNA-135a inhibits cancer cell proliferation by targeting the c-MYC oncogene in renal cell carcinoma. Cancer Sci. 2013;104:304-12 pubmed publisher

Buler M, Aatsinki S, Izzi V, Hakkola J. Metformin reduces hepatic expression of SIRT3, the mitochondrial deacetylase controlling energy metabolism. PLoS ONE. 2012;7:e49863 pubmed publisher

Naem E, Haas M, Wong N, Mooradian A. Endoplasmic reticulum stress in HepG2 cells inhibits apolipoprotein A-I secretion. Life Sci. 2013;92:72-80 pubmed publisher

Helias V, Saison C, Peyrard T, Vera E, Prehu C, Cartron J, et al. Molecular analysis of the rare in(Lu) blood type: toward decoding the phenotypic outcome of haploinsufficiency for the transcription factor KLF1. Hum Mutat. 2013;34:221-8 pubmed publisher

Zhang K, Dai X, Wallingford M, Mager J. Depletion of Suds3 reveals an essential role in early lineage specification. Dev Biol. 2013;373:359-72 pubmed publisher

Raftogianni A, Stamatakis A, Papadopoulou A, Vougas K, Anagnostopoulos A, Stylianopoulou F, et al. Effects of an early experience of reward through maternal contact or its denial on laterality of protein expression in the developing rat hippocampus. PLoS ONE. 2012;7:e48337 pubmed publisher

Dalvai M, Bellucci L, Fleury L, Lavigne A, Moutahir F, Bystricky K. H2A.Z-dependent crosstalk between enhancer and promoter regulates cyclin D1 expression. Oncogene. 2013;32:4243-51 pubmed publisher

Yu M, Chen Y, He Y, Podd A, Fu G, Wright J, et al. Critical role of B cell lymphoma 10 in BAFF-regulated NF-?B activation and survival of anergic B cells. J Immunol. 2012;189:5185-93 pubmed publisher

Dziembowska M, Milek J, Janusz A, Rejmak E, Romanowska E, Gorkiewicz T, et al. Activity-dependent local translation of matrix metalloproteinase-9. J Neurosci. 2012;32:14538-47 pubmed publisher

Hong M, Bao L, Kefaloyianni E, Agullo Pascual E, Chkourko H, Foster M, et al. Heterogeneity of ATP-sensitive K+ channels in cardiac myocytes: enrichment at the intercalated disk. J Biol Chem. 2012;287:41258-67 pubmed publisher

Goldstein I, Rivlin N, Shoshana O, Ezra O, Madar S, Goldfinger N, et al. Chemotherapeutic agents induce the expression and activity of their clearing enzyme CYP3A4 by activating p53. Carcinogenesis. 2013;34:190-8 pubmed publisher

Feldkirchner S, Schessl J, Muller S, Schoser B, Hanisch F. Patient-specific protein aggregates in myofibrillar myopathies: laser microdissection and differential proteomics for identification of plaque components. Proteomics. 2012;12:3598-609 pubmed publisher

Grassian A, Lin F, Barrett R, Liu Y, Jiang W, Korpal M, et al. Isocitrate dehydrogenase (IDH) mutations promote a reversible ZEB1/microRNA (miR)-200-dependent epithelial-mesenchymal transition (EMT). J Biol Chem. 2012;287:42180-94 pubmed publisher

Vargovic P, Ukropec J, Laukova M, Kurdiova T, Balaz M, Manz B, et al. Repeated immobilization stress induces catecholamine production in rat mesenteric adipocytes. Stress. 2013;16:340-52 pubmed publisher

Matsubara T, Tanaka N, Sato M, Kang D, Krausz K, Flanders K, et al. TGF-?-SMAD3 signaling mediates hepatic bile acid and phospholipid metabolism following lithocholic acid-induced liver injury. J Lipid Res. 2012;53:2698-707 pubmed publisher

Tiedje C, Ronkina N, Tehrani M, Dhamija S, Laass K, Holtmann H, et al. The p38/MK2-driven exchange between tristetraprolin and HuR regulates AU-rich element-dependent translation. PLoS Genet. 2012;8:e1002977 pubmed publisher

Wither R, Lang M, Zhang L, Eubanks J. Regional MeCP2 expression levels in the female MeCP2-deficient mouse brain correlate with specific behavioral impairments. Exp Neurol. 2013;239:49-59 pubmed publisher

González Santamaría J, Campagna M, Ortega Molina A, Marcos Villar L, de la Cruz Herrera C, Gonzalez D, et al. Regulation of the tumor suppressor PTEN by SUMO. Cell Death Dis. 2012;3:e393 pubmed publisher

Shibuya T, Tsujimoto Y. Deleterious effects of mitochondrial ROS generated by KillerRed photodynamic action in human cell lines and C. elegans. J Photochem Photobiol B. 2012;117:1-12 pubmed publisher

Brosh R, Assia Alroy Y, Molchadsky A, Bornstein C, Dekel E, Madar S, et al. p53 counteracts reprogramming by inhibiting mesenchymal-to-epithelial transition. Cell Death Differ. 2013;20:312-20 pubmed publisher

Humbert M, Mueller C, Fey M, Tschan M. Inhibition of damage-regulated autophagy modulator-1 (DRAM-1) impairs neutrophil differentiation of NB4 APL cells. Leuk Res. 2012;36:1552-6 pubmed publisher

Linz D, Hohl M, Mahfoud F, Reil J, Linz W, Hübschle T, et al. Cardiac remodeling and myocardial dysfunction in obese spontaneously hypertensive rats. J Transl Med. 2012;10:187 pubmed publisher

Lee J, Lee J, Trembly J, Wilusz J, Tian B, Wilusz C. The PARN deadenylase targets a discrete set of mRNAs for decay and regulates cell motility in mouse myoblasts. PLoS Genet. 2012;8:e1002901 pubmed publisher

Richerioux N, Blondeau C, Wiedemann A, Remy S, Vautherot J, Denesvre C. Rho-ROCK and Rac-PAK signaling pathways have opposing effects on the cell-to-cell spread of Marek's Disease Virus. PLoS ONE. 2012;7:e44072 pubmed publisher

Dorval V, Smith P, Delay C, Calvo E, Planel E, Zommer N, et al. Gene network and pathway analysis of mice with conditional ablation of Dicer in post-mitotic neurons. PLoS ONE. 2012;7:e44060 pubmed publisher

Chaves K, Turaça L, Pesquero J, Mennecier G, Dagli M, Chammas R, et al. Fibronectin expression is decreased in metastatic renal cell carcinoma following endostatin gene therapy. Biomed Pharmacother. 2012;66:464-8 pubmed publisher

Kleinschmidt M, de Graaf P, van Teeffelen H, Timmers H. Cell cycle regulation by the PRMT6 arginine methyltransferase through repression of cyclin-dependent kinase inhibitors. PLoS ONE. 2012;7:e41446 pubmed publisher

Kumar P, Kumar P, Lindberg L, Thirkill T, Ji J, Martsching L, et al. The MUC1 extracellular domain subunit is found in nuclear speckles and associates with spliceosomes. PLoS ONE. 2012;7:e42712 pubmed publisher

Kutay H, Klepper C, Wang B, Hsu S, Datta J, Yu L, et al. Reduced susceptibility of DNA methyltransferase 1 hypomorphic (Dnmt1N/+) mice to hepatic steatosis upon feeding liquid alcohol diet. PLoS ONE. 2012;7:e41949 pubmed publisher

Kalo E, Kogan Sakin I, Solomon H, Bar Nathan E, Shay M, Shetzer Y, et al. Mutant p53R273H attenuates the expression of phase 2 detoxifying enzymes and promotes the survival of cells with high levels of reactive oxygen species. J Cell Sci. 2012;125:5578-86 pubmed publisher

Datta J, Ghoshal K, Motiwala T, Jacob S. Novel Insights into the Molecular Mechanism of Action of DNA Hypomethylating Agents: Role of Protein Kinase C ? in Decitabine-Induced Degradation of DNA Methyltransferase 1. Genes Cancer. 2012;3:71-81 pubmed publisher

Dominguez M, Ayoub A, Rakic P. POU-III transcription factors (Brn1, Brn2, and Oct6) influence neurogenesis, molecular identity, and migratory destination of upper-layer cells of the cerebral cortex. Cereb Cortex. 2013;23:2632-43 pubmed publisher

Saykally J, Rachmany L, Hatic H, Shaer A, Rubovitch V, Pick C, et al. The nuclear factor erythroid 2-like 2 activator, tert-butylhydroquinone, improves cognitive performance in mice after mild traumatic brain injury. Neuroscience. 2012;223:305-14 pubmed publisher

Wanka C, Steinbach J, Rieger J. Tp53-induced glycolysis and apoptosis regulator (TIGAR) protects glioma cells from starvation-induced cell death by up-regulating respiration and improving cellular redox homeostasis. J Biol Chem. 2012;287:33436-46 pubmed

Sanchez A, Tripathy D, Yin X, Desobry K, Martinez J, Riley J, et al. p38 MAPK: a mediator of hypoxia-induced cerebrovascular inflammation. J Alzheimers Dis. 2012;32:587-97 pubmed publisher

Huang W, Sala Newby G, Susana A, Johnson J, Newby A. Classical macrophage activation up-regulates several matrix metalloproteinases through mitogen activated protein kinases and nuclear factor-?B. PLoS ONE. 2012;7:e42507 pubmed publisher

Tai H, Serrano Pozo A, Hashimoto T, Frosch M, Spires Jones T, Hyman B. The synaptic accumulation of hyperphosphorylated tau oligomers in Alzheimer disease is associated with dysfunction of the ubiquitin-proteasome system. Am J Pathol. 2012;181:1426-35 pubmed publisher

Lehmann F, Feicht S, Helm F, Maurberger A, Ladinig C, Zimber Strobl U, et al. Humanized c-Myc mouse. PLoS ONE. 2012;7:e42021 pubmed publisher

Pejanovic N, Hochrainer K, Liu T, Aerne B, Soares M, Anrather J. Regulation of nuclear factor ?B (NF-?B) transcriptional activity via p65 acetylation by the chaperonin containing TCP1 (CCT). PLoS ONE. 2012;7:e42020 pubmed publisher

Zhou H, Chen S, Byun H, Chen H, Li L, Han H, et al. N-methyl-D-aspartate receptor- and calpain-mediated proteolytic cleavage of K+-Cl- cotransporter-2 impairs spinal chloride homeostasis in neuropathic pain. J Biol Chem. 2012;287:33853-64 pubmed

Chang K, Kao S, Wu Y, Tsai M, Tu H, Liu C, et al. Passenger strand miRNA miR-31* regulates the phenotypes of oral cancer cells by targeting RhoA. Oral Oncol. 2013;49:27-33 pubmed publisher

Chamberlain C, Ranum L. Mouse model of muscleblind-like 1 overexpression: skeletal muscle effects and therapeutic promise. Hum Mol Genet. 2012;21:4645-54 pubmed publisher

Taxman D, Swanson K, Broglie P, Wen H, Holley Guthrie E, Huang M, et al. Porphyromonas gingivalis mediates inflammasome repression in polymicrobial cultures through a novel mechanism involving reduced endocytosis. J Biol Chem. 2012;287:32791-9 pubmed

Chavali V, Tyagi S, Mishra P. MicroRNA-133a regulates DNA methylation in diabetic cardiomyocytes. Biochem Biophys Res Commun. 2012;425:668-72 pubmed publisher

Walker K, Kang E, Whalen M, Shen Y, Tesco G. Depletion of GGA1 and GGA3 mediates postinjury elevation of BACE1. J Neurosci. 2012;32:10423-37 pubmed publisher

Lin M, Frieboes L, Forootan M, Palispis W, Mozaffar T, Jafari M, et al. Biophysical stimulation induces demyelination via an integrin-dependent mechanism. Ann Neurol. 2012;72:112-23 pubmed publisher

Lv L, Zhang T, Yi Q, Huang Y, Wang Z, Hou H, et al. Tetraploid cells from cytokinesis failure induce aneuploidy and spontaneous transformation of mouse ovarian surface epithelial cells. Cell Cycle. 2012;11:2864-75 pubmed publisher

Ezponda T, Popovic R, Shah M, Martinez Garcia E, Zheng Y, Min D, et al. The histone methyltransferase MMSET/WHSC1 activates TWIST1 to promote an epithelial-mesenchymal transition and invasive properties of prostate cancer. Oncogene. 2013;32:2882-90 pubmed publisher

Gosmain Y, Cheyssac C, Masson M, Guerardel A, Poisson C, Philippe J. Pax6 is a key component of regulated glucagon secretion. Endocrinology. 2012;153:4204-15 pubmed publisher

Churko J, Kelly J, Macdonald A, Lee J, SAMPSON J, Bai D, et al. The G60S Cx43 mutant enhances keratinocyte proliferation and differentiation. Exp Dermatol. 2012;21:612-8 pubmed publisher

Yamasaki T, Seki N, Yamada Y, Yoshino H, Hidaka H, Chiyomaru T, et al. Tumor suppressive microRNA?138 contributes to cell migration and invasion through its targeting of vimentin in renal cell carcinoma. Int J Oncol. 2012;41:805-17 pubmed publisher

Simeonova I, Lejour V, Bardot B, Bouarich Bourimi R, Morin A, Fang M, et al. Fuzzy tandem repeats containing p53 response elements may define species-specific p53 target genes. PLoS Genet. 2012;8:e1002731 pubmed publisher

Danglot L, Freret T, Le Roux N, Narboux Nême N, Burgo A, Hyenne V, et al. Vezatin is essential for dendritic spine morphogenesis and functional synaptic maturation. J Neurosci. 2012;32:9007-22 pubmed publisher

Martelli A, Friedman L, Reutenauer L, Messaddeq N, Perlman S, Lynch D, et al. Clinical data and characterization of the liver conditional mouse model exclude neoplasia as a non-neurological manifestation associated with Friedreich's ataxia. Dis Model Mech. 2012;5:860-9 pubmed publisher

Reverte I, Klein A, Ratner C, Domingo J, Colomina M. Behavioral phenotype and BDNF differences related to apoE isoforms and sex in young transgenic mice. Exp Neurol. 2012;237:116-25 pubmed publisher

Ye Z, Li D, Byun H, Li L, Pan H. NKCC1 upregulation disrupts chloride homeostasis in the hypothalamus and increases neuronal activity-sympathetic drive in hypertension. J Neurosci. 2012;32:8560-8 pubmed publisher

Nakagawa S, Ip J, Shioi G, Tripathi V, Zong X, Hirose T, et al. Malat1 is not an essential component of nuclear speckles in mice. RNA. 2012;18:1487-99 pubmed publisher

Shibasaki T, Tokunaga A, Sakamoto R, Sagara H, Noguchi S, Sasaoka T, et al. PTB deficiency causes the loss of adherens junctions in the dorsal telencephalon and leads to lethal hydrocephalus. Cereb Cortex. 2013;23:1824-35 pubmed publisher

Hu Z, Du J, Yang L, Zhu Y, Yang Y, Zheng D, et al. GEP100/Arf6 is required for epidermal growth factor-induced ERK/Rac1 signaling and cell migration in human hepatoma HepG2 cells. PLoS ONE. 2012;7:e38777 pubmed publisher

Urasaki Y, Johlfs M, Fiscus R, Le T. Imaging immune and metabolic cells of visceral adipose tissues with multimodal nonlinear optical microscopy. PLoS ONE. 2012;7:e38418 pubmed publisher

Bielenberg D, Seth A, Shimizu A, Pelton K, Cristofaro V, Ramachandran A, et al. Increased smooth muscle contractility in mice deficient for neuropilin 2. Am J Pathol. 2012;181:548-59 pubmed publisher

Horiuchi R, Akimoto T, Hong Z, Ushida T. Cyclic mechanical strain maintains Nanog expression through PI3K/Akt signaling in mouse embryonic stem cells. Exp Cell Res. 2012;318:1726-32 pubmed publisher

Lin H, Chen Y, Hsu W, Yang C, Kao C, Tsai T. Resveratrol helps recovery from fatty liver and protects against hepatocellular carcinoma induced by hepatitis B virus X protein in a mouse model. Cancer Prev Res (Phila). 2012;5:952-62 pubmed publisher

Karbalaei M, Rippe C, Albinsson S, Ekman M, Mansten A, Uvelius B, et al. Impaired contractility and detrusor hypertrophy in cavin-1-deficient mice. Eur J Pharmacol. 2012;689:179-85 pubmed publisher

Steyn F, Ngo S, Lee J, Leong J, Buckley A, Veldhuis J, et al. Impairments to the GH-IGF-I axis in hSOD1G93A mice give insight into possible mechanisms of GH dysregulation in patients with amyotrophic lateral sclerosis. Endocrinology. 2012;153:3735-46 pubmed publisher

Rodrigues L, Chung Y, Al Saffar N, Sharp S, Jackson L, Banerji U, et al. Effects of HSP90 inhibitor 17-allylamino-17-demethoxygeldanamycin (17-AAG) on NEU/HER2 overexpressing mammary tumours in MMTV-NEU-NT mice monitored by Magnetic Resonance Spectroscopy. BMC Res Notes. 2012;5:250 pubmed publisher

Zimmermann M, Arachchige Don A, Donaldson M, Dallapiazza R, Cowan C, Horne M. Elevated cyclin G2 expression intersects with DNA damage checkpoint signaling and is required for a potent G2/M checkpoint arrest response to doxorubicin. J Biol Chem. 2012;287:22838-53 pubmed publisher

Bedoyan J, Schaibley V, Peng W, Bai Y, Mondal K, Shetty A, et al. Disruption of RAB40AL function leads to Martin--Probst syndrome, a rare X-linked multisystem neurodevelopmental human disorder. J Med Genet. 2012;49:332-40 pubmed publisher

Kinoshita Y, Kalir T, Dottino P, Kohtz D. Nuclear distributions of NUP62 and NUP214 suggest architectural diversity and spatial patterning among nuclear pore complexes. PLoS ONE. 2012;7:e36137 pubmed publisher

Li Y, Paonessa J, Zhang Y. Mechanism of chemical activation of Nrf2. PLoS ONE. 2012;7:e35122 pubmed publisher

Lim S, Trzeciakowski J, Sreenivasappa H, Dangott L, Trache A. RhoA-induced cytoskeletal tension controls adaptive cellular remodeling to mechanical signaling. Integr Biol (Camb). 2012;4:615-27 pubmed publisher

Majumder M, Tutunea Fatan E, Xin X, Rodriguez Torres M, Torres Garcia J, Wiebe R, et al. Co-expression of ?9?1 integrin and VEGF-D confers lymphatic metastatic ability to a human breast cancer cell line MDA-MB-468LN. PLoS ONE. 2012;7:e35094 pubmed publisher

Lacruz R, Nakayama Y, Holcroft J, Nguyen V, Somogyi Ganss E, Snead M, et al. Targeted overexpression of amelotin disrupts the microstructure of dental enamel. PLoS ONE. 2012;7:e35200 pubmed publisher

Parikh N, Shuck R, Nguyen T, Herron A, Donehower L. Mouse tissues that undergo neoplastic progression after K-Ras activation are distinguished by nuclear translocation of phospho-Erk1/2 and robust tumor suppressor responses. Mol Cancer Res. 2012;10:845-55 pubmed publisher

Oh S, Sullivan K, Wilkinson J, Backus C, Hayes J, Sakowski S, et al. Neurodegeneration and early lethality in superoxide dismutase 2-deficient mice: a comprehensive analysis of the central and peripheral nervous systems. Neuroscience. 2012;212:201-13 pubmed publisher

Chhatriwala M, Cipolat S, Sevilla L, Nachat R, Watt F. Exons 5-15 of kazrin are dispensable for murine epidermal morphogenesis and homeostasis. J Invest Dermatol. 2012;132:1977-87 pubmed publisher

Evdokimovskaya Y, Skarga Y, Vrublevskaya V, Morenkov O. Release of the glucose-regulated protein 94 by baby hamster kidney cells. Cell Biochem Funct. 2012;30:558-62 pubmed publisher

Federzoni E, Valk P, Torbett B, Haferlach T, Lowenberg B, Fey M, et al. PU.1 is linking the glycolytic enzyme HK3 in neutrophil differentiation and survival of APL cells. Blood. 2012;119:4963-70 pubmed publisher

Doroudi M, Schwartz Z, Boyan B. Phospholipase A2 activating protein is required for 1?,25-dihydroxyvitamin D3 dependent rapid activation of protein kinase C via Pdia3. J Steroid Biochem Mol Biol. 2012;132:48-56 pubmed publisher

Sato A, Ohtaki H, Tsumuraya T, Song D, Ohara K, Asano M, et al. Interleukin-1 participates in the classical and alternative activation of microglia/macrophages after spinal cord injury. J Neuroinflammation. 2012;9:65 pubmed publisher

Corona B, Machingal M, Criswell T, Vadhavkar M, Dannahower A, Bergman C, et al. Further development of a tissue engineered muscle repair construct in vitro for enhanced functional recovery following implantation in vivo in a murine model of volumetric muscle loss injury. Tissue Eng Part A. 2012;18:1213-28 pubmed publisher

Lee Y, Sooranna S, Terzidou V, Christian M, Brosens J, Huhtinen K, et al. Interactions between inflammatory signals and the progesterone receptor in regulating gene expression in pregnant human uterine myocytes. J Cell Mol Med. 2012;16:2487-503 pubmed publisher

Orr S, Boutz D, Wang R, Chronis C, Lea N, Thayaparan T, et al. Proteomic and protein interaction network analysis of human T lymphocytes during cell-cycle entry. Mol Syst Biol. 2012;8:573 pubmed publisher

Thway K, Selfe J, Shipley J. Immunohistochemical detection of glypican-5 in paraffin-embedded material: an optimized method for a novel research antibody. Appl Immunohistochem Mol Morphol. 2012;20:189-95 pubmed publisher

Balestrini J, Chaudhry S, Sarrazy V, Koehler A, Hinz B. The mechanical memory of lung myofibroblasts. Integr Biol (Camb). 2012;4:410-21 pubmed publisher

Fiszer A, Olejniczak M, Switonski P, Wroblewska J, Wisniewska Kruk J, Mykowska A, et al. An evaluation of oligonucleotide-based therapeutic strategies for polyQ diseases. BMC Mol Biol. 2012;13:6 pubmed publisher

Youn M, Yokoyama A, Fujiyama Nakamura S, Ohtake F, Minehata K, Yasuda H, et al. JMJD5, a Jumonji C (JmjC) domain-containing protein, negatively regulates osteoclastogenesis by facilitating NFATc1 protein degradation. J Biol Chem. 2012;287:12994-3004 pubmed publisher

Yamashita T, Tadami C, Nishimoto Y, Hideyama T, Kimura D, Suzuki T, et al. RNA editing of the Q/R site of GluA2 in different cultured cell lines that constitutively express different levels of RNA editing enzyme ADAR2. Neurosci Res. 2012;73:42-8 pubmed publisher

Qi Y, Fu X, Xiong Z, Zhang H, Hill S, Rowan B, et al. Methylseleninic acid enhances paclitaxel efficacy for the treatment of triple-negative breast cancer. PLoS ONE. 2012;7:e31539 pubmed publisher

Dryden N, Sperone A, Martin Almedina S, Hannah R, Birdsey G, Khan S, et al. The transcription factor Erg controls endothelial cell quiescence by repressing activity of nuclear factor (NF)-κB p65. J Biol Chem. 2012;287:12331-42 pubmed publisher

Turlo K, Noel O, Vora R, Larussa M, Fassler R, Hall Glenn F, et al. An essential requirement for ?1 integrin in the assembly of extracellular matrix proteins within the vascular wall. Dev Biol. 2012;365:23-35 pubmed publisher