Met/HGFR Antibody, phospho-specific (Tyr1234/1235), clone 6AT1877 | EMD Millipore MAB3731 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Met/HGFR Antibody, phospho-specific (Tyr1234/1235), clone 6AT1877

catalog :

MAB3731

quantity :

100 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

antigen modification :

phosphorylated

clone name :

6AT1877

The same clone is also sold as:

Abnova: MAB0115
LifeSpan Biosciences: LS-C96424
OriGene: AM11001PU-N

reactivity :

human

citations: 1

Reference
Savas J, Ma B, Deinhardt K, Culver B, Restituito S, Wu L, et al. A role for huntington disease protein in dendritic RNA granules. J Biol Chem. 2010;285:13142-53 pubmed publisher

product information

Catalog Number :

MAB3731

Subcategory :

Cell Signaling

Product Name :

Anti-Met/HGFR Antibody, phospho-specific (Tyr1234/1235), clone 6AT1877

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P08581

Host Name :

Mouse

Antigen :

Met/HGFR

Clone :

6AT1877

Conjugate :

Purified

Isotype :

IgG1

Product Description :

Anti-Met/HGFR Antibody, phospho-specific (Tyr1234/1235), clone 6AT1877

Cross Reactivity :

Human;Mouse

ALT Names :

c-Met, cmet, HGFR, RCCP2, met proto-oncogene (hepatocyte growth factor receptor)

Immunogen :

Synthetic phospho-peptide corresponding to residues surrounding Tyr1234/1235 of human Met.

Specificity :

Reacts with Met/HGFR (Hepatocyte growth factor receptor) only when phosphorylated at Tyr1234 and Tyr1235. The Met receptor tyrosine kinase is the prototypical member of a small subfamily of growth factor receptors that when activated, induces mitogenic, motogenic, and morphogenic cellular responses. The ligand for Met is hepatocyte growth factor/scatter factor (HGF/SF) and while normal HGF/SF-Met signaling is required for embryonic development, abnormal Met signaling has been strongly implicated in tumorigenesis, particularly in the development of invasive and metastatic phenotypes.

Package Size :

100 µg

Uses :

ELISA

Storage :

Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. During shipment, small volumes of product will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 μL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container's cap.