c-met Antibody, clone 4AT44 | EMD Millipore MAB3729 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

c-met Antibody, clone 4AT44

catalog :

MAB3729

quantity :

100 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

4AT44

The same clone is also sold as:

OriGene: TA324318, AM05937PU-N
LifeSpan Biosciences: LS-B6889, LS-C45687
Abnova: MAB1143
Bio-Rad: OBT2042

reactivity :

human, mouse

application :

western blot, flow cytometry

citations: 5

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; 1:500	Petrakova O, Terskikh V, Chernioglo E, Ashapkin V, Bragin E, Shtratnikova V, et al. Comparative analysis reveals similarities between cultured submandibular salivary gland cells and liver progenitor cells. Springerplus. 2014;3:183 pubmed publisher
	Buraschi S, Pal N, Tyler Rubinstein N, Owens R, Neill T, Iozzo R. Decorin antagonizes Met receptor activity and down-regulates {beta}-catenin and Myc levels. J Biol Chem. 2010;285:42075-85 pubmed publisher
	Savas J, Ma B, Deinhardt K, Culver B, Restituito S, Wu L, et al. A role for huntington disease protein in dendritic RNA granules. J Biol Chem. 2010;285:13142-53 pubmed publisher
	Knudsen B, Zhao P, Resau J, Cottingham S, Gherardi E, Xu E, et al. A novel multipurpose monoclonal antibody for evaluating human c-Met expression in preclinical and clinical settings. Appl Immunohistochem Mol Morphol. 2009;17:57-67 pubmed publisher
	Pozner Moulis S, Cregger M, Camp R, Rimm D. Antibody validation by quantitative analysis of protein expression using expression of Met in breast cancer as a model. Lab Invest. 2007;87:251-60 pubmed

product information

Catalog Number :

MAB3729

Subcategory :

Cell Signaling

Product Name :

Anti-c-met Antibody, clone 4AT44

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P08581

Host Name :

Mouse

Antigen :

c-met

Clone :

4AT44

Conjugate :

Purified

Isotype :

IgG1

Product Description :

Anti-c-met Antibody, clone 4AT44

Cross Reactivity :

Human;Mouse

ALT Names :

Hepatocyte Growth Factor Receptor, HGFR

Immunogen :

Purified recombinant catalytic domain of human Met

Specificity :

Reacts with c-met/HGFR (Hepatocyte growth factor receptor). The Met receptor tyrosine kinase is the prototypical member of a small subfamily of growth factor receptors that when activated, induces mitogenic, motogenic, and morphogenic cellular responses. The ligand for c-met is hepatocyte growth factor/scatter factor (HGF/SF) and while normal HGF/SF-Met signaling is required for embryonic development, abnormal c-met signaling has been strongly implicated in tumorigenesis, particularly in the development of invasive and metastatic phenotypes.

Package Size :

100 µg

Uses :

Western Blotting

Storage :

Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.