| Published Application/Species/Sample/Dilution | Reference |
|---|
- immunohistochemistry - paraffin section; mouse; 1:1000; loading ...; fig 4b
- western blot; mouse; 1:1000; loading ...; fig ef4-1b
| Pakarinen E, Danilova T, Voikar V, Chmielarz P, Piepponen P, Airavaara M, et al. MANF Ablation Causes Prolonged Activation of the UPR without Neurodegeneration in the Mouse Midbrain Dopamine System. Eneuro. 2020;7: pubmed publisher |
- immunohistochemistry; mouse; 1:1000; loading ...; fig 3c
| Giguère N, Delignat Lavaud B, Herborg F, Voisin A, Li Y, Jacquemet V, et al. Increased vulnerability of nigral dopamine neurons after expansion of their axonal arborization size through D2 dopamine receptor conditional knockout. PLoS Genet. 2019;15:e1008352 pubmed publisher |
- western blot; rat; 1:1000; loading ...; fig 1c
- immunocytochemistry; human; loading ...; fig 8c
| Cartier E, Garcia Olivares J, Janezic E, Viana J, Moore M, Lin M, et al. The SUMO-Conjugase Ubc9 Prevents the Degradation of the Dopamine Transporter, Enhancing Its Cell Surface Level and Dopamine Uptake. Front Cell Neurosci. 2019;13:35 pubmed publisher |
- immunohistochemistry - frozen section; mouse; loading ...; tbl 1
| Cao M, Wu Y, Ashrafi G, McCartney A, Wheeler H, Bushong E, et al. Parkinson Sac Domain Mutation in Synaptojanin 1 Impairs Clathrin Uncoating at Synapses and Triggers Dystrophic Changes in Dopaminergic Axons. Neuron. 2017;93:882-896.e5 pubmed publisher |
- immunohistochemistry - free floating section; mouse; 1:200; loading ...; fig 6k
| Stott S, Hayat S, Carnwath T, Garas S, Sleeman J, Barker R. CD24 expression does not affect dopamine neuronal survival in a mouse model of Parkinson's disease. PLoS ONE. 2017;12:e0171748 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 3e
| Stayte S, Rentsch P, Tröscher A, Bamberger M, Li K, Vissel B. Activin A Inhibits MPTP and LPS-Induced Increases in Inflammatory Cell Populations and Loss of Dopamine Neurons in the Mouse Midbrain In Vivo. PLoS ONE. 2017;12:e0167211 pubmed publisher |
- immunohistochemistry; mouse; 1:1000; loading ...
| Cádiz Moretti B, Abellán Álvaro M, Pardo Bellver C, Martinez Garcia F, Lanuza E. Afferent and Efferent Connections of the Cortex-Amygdala Transition Zone in Mice. Front Neuroanat. 2016;10:125 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 4c
| Zha J, Liu X, Zhu J, Liu S, Lu S, Xu P, et al. A scFv antibody targeting common oligomeric epitope has potential for treating several amyloidoses. Sci Rep. 2016;6:36631 pubmed publisher |
- western blot; mouse; loading ...; fig 7a
| Fukada M, Nakayama A, Mamiya T, Yao T, Kawaguchi Y. Dopaminergic abnormalities in Hdac6-deficient mice. Neuropharmacology. 2016;110:470-479 pubmed publisher |
- western blot; mouse; 1:5000; loading ...; fig 1a
| Cockerham R, Liu S, Cachope R, Kiyokage E, Cheer J, Shipley M, et al. Subsecond Regulation of Synaptically Released Dopamine by COMT in the Olfactory Bulb. J Neurosci. 2016;36:7779-85 pubmed publisher |
- immunohistochemistry - frozen section; mouse; 1:1000; loading ...; fig 2f
| Doucet Beaupré H, Gilbert C, Profes M, Chabrat A, Pacelli C, Giguère N, et al. Lmx1a and Lmx1b regulate mitochondrial functions and survival of adult midbrain dopaminergic neurons. Proc Natl Acad Sci U S A. 2016;113:E4387-96 pubmed publisher |
- immunohistochemistry; mouse; 1:1000; fig 2
| Ahn M, Kalume F, Pitstick R, Oehler A, Carlson G, Dearmond S. Brain Aggregates: An Effective In Vitro Cell Culture System Modeling Neurodegenerative Diseases. J Neuropathol Exp Neurol. 2016;75:256-62 pubmed publisher |
- western blot; mouse; 1:200; loading ...; fig s6a
| Ren W, Centeno M, Berger S, Wu Y, Na X, Liu X, et al. The indirect pathway of the nucleus accumbens shell amplifies neuropathic pain. Nat Neurosci. 2016;19:220-2 pubmed publisher |
- immunohistochemistry; mouse; 1:1000; fig 8
| Gazea M, Tasouri E, Tolve M, Bosch V, Kabanova A, Gojak C, et al. Primary cilia are critical for Sonic hedgehog-mediated dopaminergic neurogenesis in the embryonic midbrain. Dev Biol. 2016;409:55-71 pubmed publisher |
- western blot; mouse; loading ...; fig 8b
| Dearborn J, Harmon S, Fowler S, O Malley K, Taylor G, Sands M, et al. Comprehensive functional characterization of murine infantile Batten disease including Parkinson-like behavior and dopaminergic markers. Sci Rep. 2015;5:12752 pubmed publisher |
- immunohistochemistry; mouse; 1:1000; fig 5
| Laguna A, Schintu N, Nobre A, Alvarsson A, Volakakis N, Jacobsen J, et al. Dopaminergic control of autophagic-lysosomal function implicates Lmx1b in Parkinson's disease. Nat Neurosci. 2015;18:826-35 pubmed publisher |
- immunocytochemistry; mouse; 1:1000
| Xenias H, Ibáñez Sandoval O, Koós T, Tepper J. Are striatal tyrosine hydroxylase interneurons dopaminergic?. J Neurosci. 2015;35:6584-99 pubmed publisher |
- immunohistochemistry - frozen section; mouse; 1:1000; loading ...; fig 5a
| Stayte S, Rentsch P, Li K, Vissel B. Activin A protects midbrain neurons in the 6-hydroxydopamine mouse model of Parkinson's disease. PLoS ONE. 2015;10:e0124325 pubmed publisher |
- immunohistochemistry - free floating section; mouse; 1:1000
| Depboylu C, Rösler T, de Andrade A, Oertel W, Höglinger G. Systemically administered neuregulin-1β1 rescues nigral dopaminergic neurons via the ErbB4 receptor tyrosine kinase in MPTP mouse models of Parkinson's disease. J Neurochem. 2015;133:590-7 pubmed publisher |
- western blot; rat; 1:2000
| GarcÃa Pérez D, Núñez C, Laorden M, Milanés M. Regulation of dopaminergic markers expression in response to acute and chronic morphine and to morphine withdrawal. Addict Biol. 2016;21:374-86 pubmed publisher |
- immunocytochemistry; mouse; 1:500
| Vergaño Vera E, Diaz Guerra E, Rodríguez Traver E, Méndez Gómez H, Solis O, Pignatelli J, et al. Nurr1 blocks the mitogenic effect of FGF-2 and EGF, inducing olfactory bulb neural stem cells to adopt dopaminergic and dopaminergic-GABAergic neuronal phenotypes. Dev Neurobiol. 2015;75:823-41 pubmed publisher |
- western blot; human; 1:1000
| Bowton E, Saunders C, Reddy I, Campbell N, Hamilton P, Henry L, et al. SLC6A3 coding variant Ala559Val found in two autism probands alters dopamine transporter function and trafficking. Transl Psychiatry. 2014;4:e464 pubmed publisher |
- immunohistochemistry - frozen section; rat; 1:100
| Gao J, Tu S, Liu J, Zhang J, Huang Y, Han M, et al. An-jun-ning, a traditional herbal formula, attenuates spontaneous withdrawal symptoms via modulation of the dopamine system in morphine-dependent rats. BMC Complement Altern Med. 2014;14:308 pubmed publisher |
- immunohistochemistry; mouse; 1:1,000
| Quina L, Tempest L, Ng L, Harris J, Ferguson S, Jhou T, et al. Efferent pathways of the mouse lateral habenula. J Comp Neurol. 2015;523:32-60 pubmed publisher |
- immunocytochemistry; mouse
| Montgomery T, Steinkellner T, Sucic S, Koban F, Schüchner S, Ogris E, et al. Axonal targeting of the serotonin transporter in cultured rat dorsal raphe neurons is specified by SEC24C-dependent export from the endoplasmic reticulum. J Neurosci. 2014;34:6344-6351 pubmed publisher |
- immunohistochemistry - free floating section; mouse; 1:300
| Ting J, Feng G. Recombineering strategies for developing next generation BAC transgenic tools for optogenetics and beyond. Front Behav Neurosci. 2014;8:111 pubmed publisher |
- immunohistochemistry; human; 1:250
| Kim H, Andreazza A, Yeung P, Isaacs Trepanier C, Young L. Oxidation and nitration in dopaminergic areas of the prefrontal cortex from patients with bipolar disorder and schizophrenia. J Psychiatry Neurosci. 2014;39:276-85 pubmed |
- immunohistochemistry; rat; 1:20,000
| Garzón M, Pickel V. Somatodendritic targeting of M5 muscarinic receptor in the rat ventral tegmental area: implications for mesolimbic dopamine transmission. J Comp Neurol. 2013;521:2927-46 pubmed publisher |
- immunohistochemistry - frozen section; mouse; 1:300
| Witkovsky P, G briel R, Krizaj D. Anatomical and neurochemical characterization of dopaminergic interplexiform processes in mouse and rat retinas. J Comp Neurol. 2008;510:158-74 pubmed publisher |
| Lebowitz J, Pino J, Mackie P, Lin M, Hurst C, Divita K, et al. Clustered Kv2.1 decreases dopamine transporter activity and internalization. J Biol Chem. 2019;294:6957-6971 pubmed publisher |
| Bäck S, Necarsulmer J, Whitaker L, Coke L, Koivula P, Heathward E, et al. Neuron-Specific Genome Modification in the Adult Rat Brain Using CRISPR-Cas9 Transgenic Rats. Neuron. 2019;102:105-119.e8 pubmed publisher |
| Rentsch P, Stayte S, Morris G, Vissel B. Time dependent degeneration of the nigrostriatal tract in mice with 6-OHDA lesioned medial forebrain bundle and the effect of activin A on L-Dopa induced dyskinesia. BMC Neurosci. 2019;20:5 pubmed publisher |
| Campbell N, Shekar A, Aguilar J, Peng D, Navratna V, Yang D, et al. Structural, functional, and behavioral insights of dopamine dysfunction revealed by a deletion in SLC6A3. Proc Natl Acad Sci U S A. 2019;116:3853-3862 pubmed publisher |
| Paul E, Kalk E, Tossell K, Irvine E, Franks N, Wisden W, et al. nNOS-Expressing Neurons in the Ventral Tegmental Area and Substantia Nigra Pars Compacta. Eneuro. 2018;5: pubmed publisher |
| Su J, Huang P, Qin M, Lu Q, Sang X, Cai Y, et al. Reduction of HIP2 expression causes motor function impairment and increased vulnerability to dopaminergic degeneration in Parkinson's disease models. Cell Death Dis. 2018;9:1020 pubmed publisher |
| Uenaka T, Satake W, Cha P, Hayakawa H, Baba K, Jiang S, et al. In silico drug screening by using genome-wide association study data repurposed dabrafenib, an anti-melanoma drug, for Parkinson's disease. Hum Mol Genet. 2018;27:3974-3985 pubmed publisher |
| Hong W, Wasko M, Wilkinson D, Hiranita T, Li L, Hayashi S, et al. Dopamine Transporter Dynamics of N-Substituted Benztropine Analogs with Atypical Behavioral Effects. J Pharmacol Exp Ther. 2018;366:527-540 pubmed publisher |
| Soto M, Herzog C, Pacheco J, Fujisaka S, Bullock K, Clish C, et al. Gut microbiota modulate neurobehavior through changes in brain insulin sensitivity and metabolism. Mol Psychiatry. 2018;23:2287-2301 pubmed publisher |
| Back M, Ha H, Fu Z, Choi J, Piao Y, Won J, et al. Activation of neutral sphingomyelinase 2 by starvation induces cell-protective autophagy via an increase in Golgi-localized ceramide. Cell Death Dis. 2018;9:670 pubmed publisher |
| Gowrishankar R, Gresch P, Davis G, Katamish R, Riele J, Stewart A, et al. Region-Specific Regulation of Presynaptic Dopamine Homeostasis by D2 Autoreceptors Shapes the In Vivo Impact of the Neuropsychiatric Disease-Associated DAT Variant Val559. J Neurosci. 2018;38:5302-5312 pubmed publisher |
| Sorkina T, Ma S, Larsen M, Watkins S, Sorkin A. Small molecule induced oligomerization, clustering and clathrin-independent endocytosis of the dopamine transporter. elife. 2018;7: pubmed publisher |
| Schommer J, Marwarha G, Schommer T, Flick T, Lund J, Ghribi O. 27-Hydroxycholesterol increases α-synuclein protein levels through proteasomal inhibition in human dopaminergic neurons. BMC Neurosci. 2018;19:17 pubmed publisher |
| Bhattacharya S, Ma Y, Dunn A, Bradner J, Scimemi A, Miller G, et al. NMDA receptor blockade ameliorates abnormalities of spike firing of subthalamic nucleus neurons in a parkinsonian nonhuman primate. J Neurosci Res. 2018;96:1324-1335 pubmed publisher |
| Xu S, Tu S, Gao J, Liu J, Guo Z, Zhang J, et al. Protective and restorative effects of the traditional Chinese medicine Jitai tablet against methamphetamine-induced dopaminergic neurotoxicity. BMC Complement Altern Med. 2018;18:76 pubmed publisher |
| Watanabe M, Narita M, Hamada Y, Yamashita A, Tamura H, Ikegami D, et al. Activation of ventral tegmental area dopaminergic neurons reverses pathological allodynia resulting from nerve injury or bone cancer. Mol Pain. 2018;14:1744806918756406 pubmed publisher |
| Bobela W, Nazeeruddin S, Knott G, Aebischer P, Schneider B. Modulating the catalytic activity of AMPK has neuroprotective effects against ?-synuclein toxicity. Mol Neurodegener. 2017;12:80 pubmed publisher |
| Rahbek Clemmensen T, Lycas M, Erlendsson S, Eriksen J, Apuschkin M, Vilhardt F, et al. Super-resolution microscopy reveals functional organization of dopamine transporters into cholesterol and neuronal activity-dependent nanodomains. Nat Commun. 2017;8:740 pubmed publisher |
| Wu S, Fagan R, Uttamapinant C, Lifshitz L, Fogarty K, Ting A, et al. The Dopamine Transporter Recycles via a Retromer-Dependent Postendocytic Mechanism: Tracking Studies Using a Novel Fluorophore-Coupling Approach. J Neurosci. 2017;37:9438-9452 pubmed publisher |
| Bermingham D, Hardaway J, Refai O, Marks C, Snider S, Sturgeon S, et al. The Atypical MAP Kinase SWIP-13/ERK8 Regulates Dopamine Transporters through a Rho-Dependent Mechanism. J Neurosci. 2017;37:9288-9304 pubmed publisher |
| Green A, Zhan L, Eid A, Zarbl H, Guo G, Richardson J. Valproate increases dopamine transporter expression through histone acetylation and enhanced promoter binding of Nurr1. Neuropharmacology. 2017;125:189-196 pubmed publisher |
| Cheng M, Garcia Olivares J, Wasserman S, DiPietro J, Bahar I. Allosteric modulation of human dopamine transporter activity under conditions promoting its dimerization. J Biol Chem. 2017;292:12471-12482 pubmed publisher |
| Hong W, Yano H, Hiranita T, Chin F, McCurdy C, SU T, et al. The sigma-1 receptor modulates dopamine transporter conformation and cocaine binding and may thereby potentiate cocaine self-administration in rats. J Biol Chem. 2017;292:11250-11261 pubmed publisher |
| Akbar M, Nardo D, Chen M, Elshikha A, Ahamed R, Elsayed E, et al. Alpha-1 antitrypsin inhibits RANKL-induced osteoclast formation and functions. Mol Med. 2017;23:57-69 pubmed publisher |
| Gagnon D, Petryszyn S, Sanchez M, Bories C, Beaulieu J, De Koninck Y, et al. Striatal Neurons Expressing D1 and D2 Receptors are Morphologically Distinct and Differently Affected by Dopamine Denervation in Mice. Sci Rep. 2017;7:41432 pubmed publisher |
| Gracia Rubio I, Martínez Laorden E, Moscoso Castro M, Milanes M, Laorden M, Valverde O. Maternal Separation Impairs Cocaine-Induced Behavioural Sensitization in Adolescent Mice. PLoS ONE. 2016;11:e0167483 pubmed publisher |
| Holm T, Isaksen T, Glerup S, Heuck A, Bøttger P, Füchtbauer E, et al. Cognitive deficits caused by a disease-mutation in the ?3 Na(+)/K(+)-ATPase isoform. Sci Rep. 2016;6:31972 pubmed publisher |
| Stout K, Dunn A, Lohr K, Alter S, Cliburn R, Guillot T, et al. Selective Enhancement of Dopamine Release in the Ventral Pallidum of Methamphetamine-Sensitized Mice. ACS Chem Neurosci. 2016;7:1364-1373 pubmed |
| Aumann T, Raabus M, Tomas D, Prijanto A, Churilov L, Spitzer N, et al. Differences in Number of Midbrain Dopamine Neurons Associated with Summer and Winter Photoperiods in Humans. PLoS ONE. 2016;11:e0158847 pubmed publisher |
| Tomas D, Stanic D, Chua H, White K, Boon W, Horne M. Restoration of the Dopamine Transporter through Cell Therapy Improves Dyskinesia in a Rat Model of Parkinson's Disease. PLoS ONE. 2016;11:e0153424 pubmed publisher |
| Van Kampen J, Baranowski D, Robertson H, Shaw C, Kay D. The Progressive BSSG Rat Model of Parkinson's: Recapitulating Multiple Key Features of the Human Disease. PLoS ONE. 2015;10:e0139694 pubmed publisher |
| Eid L, Parent M. Morphological evidence for dopamine interactions with pallidal neurons in primates. Front Neuroanat. 2015;9:111 pubmed publisher |
| Green A, Hossain M, Tee S, Zarbl H, Guo G, Richardson J. Epigenetic Regulation of Dopamine Transporter mRNA Expression in Human Neuroblastoma Cells. Neurochem Res. 2015;40:1372-8 pubmed publisher |
| Koblinger K, Fuzesi T, Ejdrygiewicz J, Krajacic A, Bains J, Whelan P. Characterization of A11 neurons projecting to the spinal cord of mice. PLoS ONE. 2014;9:e109636 pubmed publisher |
| Domanskyi A, Alter H, Vogt M, Gass P, Vinnikov I. Transcription factors Foxa1 and Foxa2 are required for adult dopamine neurons maintenance. Front Cell Neurosci. 2014;8:275 pubmed publisher |
| Gaven F, Marin P, Claeysen S. Primary culture of mouse dopaminergic neurons. J Vis Exp. 2014;:e51751 pubmed publisher |
| Hsieh W, Chiang B. A well-refined in vitro model derived from human embryonic stem cell for screening phytochemicals with midbrain dopaminergic differentiation-boosting potential for improving Parkinson's disease. J Agric Food Chem. 2014;62:6326-36 pubmed publisher |
| Van Kampen J, Baranowski D, Kay D. Progranulin gene delivery protects dopaminergic neurons in a mouse model of Parkinson's disease. PLoS ONE. 2014;9:e97032 pubmed publisher |
| Pertek A, Meier F, Irmler M, Beckers J, Skylaki S, Endele M, et al. Simple derivation of transgene-free iPS cells by a dual recombinase approach. Mol Biotechnol. 2014;56:697-713 pubmed publisher |
| Depboylu C. Non-serine-phosphorylated tyrosine hydroxylase expressing neurons are present in mouse striatum, accumbens and cortex that increase in number following dopaminergic denervation. J Chem Neuroanat. 2014;56:35-44 pubmed publisher |
| Hiranita T, Wilkinson D, Hong W, Zou M, Kopajtic T, Soto P, et al. 2-isoxazol-3-phenyltropane derivatives of cocaine: molecular and atypical system effects at the dopamine transporter. J Pharmacol Exp Ther. 2014;349:297-309 pubmed publisher |
| Fifel K, Vezoli J, Dzahini K, Claustrat B, Leviel V, Kennedy H, et al. Alteration of daily and circadian rhythms following dopamine depletion in MPTP treated non-human primates. PLoS ONE. 2014;9:e86240 pubmed publisher |
| Kanno K, Kokubo H, Takahashi A, Koide T, Ishiura S. Enhanced prepulse inhibition and low sensitivity to a dopamine agonist in HESR1 knockout mice. J Neurosci Res. 2014;92:287-97 pubmed publisher |
| Tripathi P, Di Giovannantonio L, Sanguinetti E, Acampora D, Allegra M, Caleo M, et al. Increased dopaminergic innervation in the brain of conditional mutant mice overexpressing Otx2: effects on locomotor behavior and seizure susceptibility. Neuroscience. 2014;261:173-83 pubmed publisher |
| Ramshaw H, Xu X, Jaehne E, McCarthy P, Greenberg Z, Saleh E, et al. Locomotor hyperactivity in 14-3-3? KO mice is associated with dopamine transporter dysfunction. Transl Psychiatry. 2013;3:e327 pubmed publisher |
| Osório L, Gijsbers R, Oliveras Salvá M, Michiels A, Debyser Z, Van den Haute C, et al. Viral vectors expressing a single microRNA-based short-hairpin RNA result in potent gene silencing in vitro and in vivo. J Biotechnol. 2014;169:71-81 pubmed publisher |
| Gabriel L, Wu S, Kearney P, Bellve K, Standley C, Fogarty K, et al. Dopamine transporter endocytic trafficking in striatal dopaminergic neurons: differential dependence on dynamin and the actin cytoskeleton. J Neurosci. 2013;33:17836-46 pubmed publisher |
| Hayashizaki S, Hirai S, Ito Y, Honda Y, Arime Y, Sora I, et al. Methamphetamine increases locomotion and dopamine transporter activity in dopamine d5 receptor-deficient mice. PLoS ONE. 2013;8:e75975 pubmed publisher |
| Friend D, Keefe K. A role for D1 dopamine receptors in striatal methamphetamine-induced neurotoxicity. Neurosci Lett. 2013;555:243-7 pubmed publisher |
| Rothman S, Griffioen K, Vranis N, Ladenheim B, Cong W, Cadet J, et al. Neuronal expression of familial Parkinson's disease A53T ?-synuclein causes early motor impairment, reduced anxiety and potential sleep disturbances in mice. J Parkinsons Dis. 2013;3:215-29 pubmed publisher |
| Ageta Ishihara N, Yamakado H, Morita T, Hattori S, Takao K, Miyakawa T, et al. Chronic overload of SEPT4, a parkin substrate that aggregates in Parkinson's disease, causes behavioral alterations but not neurodegeneration in mice. Mol Brain. 2013;6:35 pubmed publisher |
| Rickhag M, Owens W, Winkler M, Strandfelt K, Rathje M, Sørensen G, et al. Membrane-permeable C-terminal dopamine transporter peptides attenuate amphetamine-evoked dopamine release. J Biol Chem. 2013;288:27534-44 pubmed publisher |
| Bäck S, Raki M, Tuominen R, Raasmaja A, Bergstrom K, Mannisto P. High correlation between in vivo [123I]?-CIT SPECT/CT imaging and post-mortem immunohistochemical findings in the evaluation of lesions induced by 6-OHDA in rats. EJNMMI Res. 2013;3:46 pubmed publisher |
| Reyes S, Cottam V, Kirik D, Double K, Halliday G. Variability in neuronal expression of dopamine receptors and transporters in the substantia nigra. Mov Disord. 2013;28:1351-9 pubmed publisher |
| Sai T, Uchida K, Nakayama H. Biochemical evaluation of the neurotoxicity of MPTP and MPP? in embryonic and newborn mice. J Toxicol Sci. 2013;38:445-58 pubmed |
| Homma D, Katoh S, Tokuoka H, Ichinose H. The role of tetrahydrobiopterin and catecholamines in the developmental regulation of tyrosine hydroxylase level in the brain. J Neurochem. 2013;126:70-81 pubmed publisher |
| Midde N, Huang X, Gomez A, Booze R, Zhan C, Zhu J. Mutation of tyrosine 470 of human dopamine transporter is critical for HIV-1 Tat-induced inhibition of dopamine transport and transporter conformational transitions. J Neuroimmune Pharmacol. 2013;8:975-87 pubmed publisher |
| Stott S, Metzakopian E, Lin W, Kaestner K, Hen R, Ang S. Foxa1 and foxa2 are required for the maintenance of dopaminergic properties in ventral midbrain neurons at late embryonic stages. J Neurosci. 2013;33:8022-34 pubmed publisher |
| Hong W, Amara S. Differential targeting of the dopamine transporter to recycling or degradative pathways during amphetamine- or PKC-regulated endocytosis in dopamine neurons. FASEB J. 2013;27:2995-3007 pubmed publisher |
| Hara S, Arawaka S, Sato H, Machiya Y, Cui C, Sasaki A, et al. Serine 129 phosphorylation of membrane-associated ?-synuclein modulates dopamine transporter function in a G protein-coupled receptor kinase-dependent manner. Mol Biol Cell. 2013;24:1649-60, S1-3 pubmed publisher |
| Fricks Gleason A, Keefe K. Evaluating the role of neuronal nitric oxide synthase-containing striatal interneurons in methamphetamine-induced dopamine neurotoxicity. Neurotox Res. 2013;24:288-97 pubmed publisher |
| Oaks A, Frankfurt M, Finkelstein D, Sidhu A. Age-dependent effects of A53T alpha-synuclein on behavior and dopaminergic function. PLoS ONE. 2013;8:e60378 pubmed publisher |
| Garcia Olivares J, Torres Salazar D, Owens W, Baust T, Siderovski D, Amara S, et al. Inhibition of dopamine transporter activity by G protein ?? subunits. PLoS ONE. 2013;8:e59788 pubmed publisher |
| Torigoe M, Yamauchi K, Tamada A, Matsuda I, Aiba A, Castellani V, et al. Role of neuropilin-2 in the ipsilateral growth of midbrain dopaminergic axons. Eur J Neurosci. 2013;37:1573-83 pubmed publisher |
| Rickhag M, Hansen F, Sørensen G, Strandfelt K, Andresen B, Gotfryd K, et al. A C-terminal PDZ domain-binding sequence is required for striatal distribution of the dopamine transporter. Nat Commun. 2013;4:1580 pubmed publisher |
| Chen R, Daining C, Sun H, Fraser R, Stokes S, Leitges M, et al. Protein kinase C? is a modulator of the dopamine D2 autoreceptor-activated trafficking of the dopamine transporter. J Neurochem. 2013;125:663-72 pubmed publisher |
| Sorkina T, Caltagarone J, Sorkin A. Flotillins regulate membrane mobility of the dopamine transporter but are not required for its protein kinase C dependent endocytosis. Traffic. 2013;14:709-24 pubmed publisher |
| Friend D, Keefe K. Glial reactivity in resistance to methamphetamine-induced neurotoxicity. J Neurochem. 2013;125:566-74 pubmed publisher |
| Ohara A, Kasahara Y, Yamamoto H, Hata H, Kobayashi H, Numachi Y, et al. Exclusive expression of VMAT2 in noradrenergic neurons increases viability of homozygous VMAT2 knockout mice. Biochem Biophys Res Commun. 2013;432:526-32 pubmed publisher |
| Jaaro Peled H, Niwa M, Foss C, Murai R, de Los Reyes S, Kamiya A, et al. Subcortical dopaminergic deficits in a DISC1 mutant model: a study in direct reference to human molecular brain imaging. Hum Mol Genet. 2013;22:1574-80 pubmed publisher |
| Piltonen M, Savolainen M, Patrikainen S, Baekelandt V, Myöhänen T, Mannisto P. Comparison of motor performance, brain biochemistry and histology of two A30P ?-synuclein transgenic mouse strains. Neuroscience. 2013;231:157-68 pubmed publisher |
| Fortin G, Bourque M, Mendez J, Leo D, Nordenankar K, Birgner C, et al. Glutamate corelease promotes growth and survival of midbrain dopamine neurons. J Neurosci. 2012;32:17477-91 pubmed publisher |
| Nakata Y, Yasuda T, Fukaya M, Yamamori S, Itakura M, Nihira T, et al. Accumulation of ?-synuclein triggered by presynaptic dysfunction. J Neurosci. 2012;32:17186-96 pubmed publisher |
| Sterky F, Pernold K, Harvey B, Lindqvist E, Hoffer B, Olson L. Glial cell line-derived neurotrophic factor partially ameliorates motor symptoms without slowing neurodegeneration in mice with respiratory chain-deficient dopamine neurons. Cell Transplant. 2013;22:1529-39 pubmed publisher |
| Busceti C, Bucci D, Molinaro G, Di Pietro P, Zangrandi L, Gradini R, et al. Lack or inhibition of dopaminergic stimulation induces a development increase of striatal tyrosine hydroxylase-positive interneurons. PLoS ONE. 2012;7:e44025 pubmed publisher |
| Seminerio M, Hansen R, Kaushal N, Zhang H, McCurdy C, Matsumoto R. The evaluation of AZ66, an optimized sigma receptor antagonist, against methamphetamine-induced dopaminergic neurotoxicity and memory impairment in mice. Int J Neuropsychopharmacol. 2013;16:1033-44 pubmed publisher |
| Kaushal N, Seminerio M, Robson M, McCurdy C, Matsumoto R. Pharmacological evaluation of SN79, a sigma (?) receptor ligand, against methamphetamine-induced neurotoxicity in vivo. Eur Neuropsychopharmacol. 2013;23:960-71 pubmed publisher |
| André P, Saubamea B, Cochois Guégan V, Marie Claire C, Cattelotte J, Smirnova M, et al. Transport of biogenic amine neurotransmitters at the mouse blood-retina and blood-brain barriers by uptake1 and uptake2. J Cereb Blood Flow Metab. 2012;32:1989-2001 pubmed publisher |
| Steinkellner T, Yang J, Montgomery T, Chen W, Winkler M, Sucic S, et al. Ca(2+)/calmodulin-dependent protein kinase II? (?CaMKII) controls the activity of the dopamine transporter: implications for Angelman syndrome. J Biol Chem. 2012;287:29627-35 pubmed publisher |
| Ulusoy A, Bjorklund T, Buck K, Kirik D. Dysregulated dopamine storage increases the vulnerability to ?-synuclein in nigral neurons. Neurobiol Dis. 2012;47:367-77 pubmed publisher |
| Muroyama A, Fujita A, Lv C, Kobayashi S, Fukuyama Y, Mitsumoto Y. Magnolol Protects against MPTP/MPP(+)-Induced Toxicity via Inhibition of Oxidative Stress in In Vivo and In Vitro Models of Parkinson's Disease. Parkinsons Dis. 2012;2012:985157 pubmed publisher |
| Baron O, Ratzka A, Grothe C. Fibroblast growth factor 2 regulates adequate nigrostriatal pathway formation in mice. J Comp Neurol. 2012;520:3949-61 pubmed publisher |
| Szego E, Outeiro T, Kermer P, Schulz J. Impairment of the septal cholinergic neurons in MPTP-treated A30P ?-synuclein mice. Neurobiol Aging. 2013;34:589-601 pubmed publisher |
| Sakrikar D, Mazei Robison M, MERGY M, Richtand N, Han Q, Hamilton P, et al. Attention deficit/hyperactivity disorder-derived coding variation in the dopamine transporter disrupts microdomain targeting and trafficking regulation. J Neurosci. 2012;32:5385-97 pubmed publisher |
| Sánchez Danés A, Richaud Patin Y, Carballo Carbajal I, Jimenez Delgado S, Caig C, Mora S, et al. Disease-specific phenotypes in dopamine neurons from human iPS-based models of genetic and sporadic Parkinson's disease. EMBO Mol Med. 2012;4:380-95 pubmed publisher |
| Cui R, Zhang G, Kang Y, Cheng Q, Tan H, Cui H, et al. Amelioratory effects of testosterone propionate supplement on behavioral, biochemical and morphological parameters in aged rats. Exp Gerontol. 2012;47:67-76 pubmed publisher |
| Fanciulli A, Misasi R, Campanelli D, Buttarelli F, Pontieri F. Dopaminergic drug-induced modulation of the expression of the dopamine transporter in peripheral blood lymphocytes in Parkinson's disease. Pharmacol Rep. 2011;63:1056-60 pubmed |
| Ziegler C, Peng M, Falk M, Polyak E, Tsika E, Ischiropoulos H, et al. Parkinson's disease-like neuromuscular defects occur in prenyl diphosphate synthase subunit 2 (Pdss2) mutant mice. Mitochondrion. 2012;12:248-57 pubmed publisher |
| Airavaara M, Harvey B, Voutilainen M, Shen H, Chou J, Lindholm P, et al. CDNF protects the nigrostriatal dopamine system and promotes recovery after MPTP treatment in mice. Cell Transplant. 2012;21:1213-23 pubmed publisher |
| Fu Y, Yuan Y, Halliday G, Rusznák Z, Watson C, Paxinos G. A cytoarchitectonic and chemoarchitectonic analysis of the dopamine cell groups in the substantia nigra, ventral tegmental area, and retrorubral field in the mouse. Brain Struct Funct. 2012;217:591-612 pubmed publisher |
| Lennington J, Pope S, Goodheart A, Drozdowicz L, Daniels S, Salamone J, et al. Midbrain dopamine neurons associated with reward processing innervate the neurogenic subventricular zone. J Neurosci. 2011;31:13078-87 pubmed publisher |
| Herzig M, Kolly C, Persohn E, Theil D, Schweizer T, Hafner T, et al. LRRK2 protein levels are determined by kinase function and are crucial for kidney and lung homeostasis in mice. Hum Mol Genet. 2011;20:4209-23 pubmed publisher |
| Kaushal N, Seminerio M, Shaikh J, Medina M, Mesangeau C, Wilson L, et al. CM156, a high affinity sigma ligand, attenuates the stimulant and neurotoxic effects of methamphetamine in mice. Neuropharmacology. 2011;61:992-1000 pubmed publisher |
| Kobayashi S, Muroyama A, Matsushima H, Yoshimura I, Mitsumoto Y. Oral administration of coenzyme Q?? reduces MPTP-induced loss of dopaminergic nerve terminals in the striatum in mice. Neurol Sci. 2012;33:195-9 pubmed publisher |
| Domanskyi A, Geissler C, Vinnikov I, Alter H, Schober A, Vogt M, et al. Pten ablation in adult dopaminergic neurons is neuroprotective in Parkinson's disease models. FASEB J. 2011;25:2898-910 pubmed publisher |
| Chadchankar H, Ihalainen J, Tanila H, Yavich L. Decreased reuptake of dopamine in the dorsal striatum in the absence of ?-synuclein. Brain Res. 2011;1382:37-44 pubmed publisher |
| Muroyama A, Kobayashi S, Mitsumoto Y. Loss of striatal dopaminergic terminals during the early stage in response to MPTP injection in C57BL/6 mice. Neurosci Res. 2011;69:352-5 pubmed publisher |
| Allen E, Carlson K, Zigmond M, Cavanaugh J. L-DOPA reverses motor deficits associated with normal aging in mice. Neurosci Lett. 2011;489:1-4 pubmed publisher |
| Sgadò P, Viaggi C, Pinna A, Marrone C, Vaglini F, Pontis S, et al. Behavioral, neurochemical, and electrophysiological changes in an early spontaneous mouse model of nigrostriatal degeneration. Neurotox Res. 2011;20:170-81 pubmed publisher |
| Cohen A, Zigmond M, Smith A. Effects of intrastriatal GDNF on the response of dopamine neurons to 6-hydroxydopamine: time course of protection and neurorestoration. Brain Res. 2011;1370:80-8 pubmed publisher |
| Conversi D, Orsini C, Colelli V, Cruciani F, Cabib S. Association between striatal accumulation of FosB/?FosB and long-term psychomotor sensitization to amphetamine in mice depends on the genetic background. Behav Brain Res. 2011;217:155-64 pubmed publisher |
| Barraud Q, Obeid I, Aubert I, Barrière G, Contamin H, McGuire S, et al. Neuroanatomical study of the A11 diencephalospinal pathway in the non-human primate. PLoS ONE. 2010;5:e13306 pubmed publisher |
| Yang J, Liao C, Pang C, Huang L, Lin Y, Chen Y, et al. Directed differentiation into neural lineages and therapeutic potential of porcine embryonic stem cells in rat Parkinson's disease model. Cell Reprogram. 2010;12:447-61 pubmed publisher |
| Hong W, Amara S. Membrane cholesterol modulates the outward facing conformation of the dopamine transporter and alters cocaine binding. J Biol Chem. 2010;285:32616-26 pubmed publisher |
| Wills J, Jones J, Haggerty T, Duka V, Joyce J, Sidhu A. Elevated tauopathy and alpha-synuclein pathology in postmortem Parkinson's disease brains with and without dementia. Exp Neurol. 2010;225:210-8 pubmed publisher |
| Bowton E, Saunders C, Erreger K, Sakrikar D, Matthies H, Sen N, et al. Dysregulation of dopamine transporters via dopamine D2 autoreceptors triggers anomalous dopamine efflux associated with attention-deficit hyperactivity disorder. J Neurosci. 2010;30:6048-57 pubmed publisher |
| Yu S, Zheng W, Xin N, Chi Z, Wang N, Nie Y, et al. Curcumin prevents dopaminergic neuronal death through inhibition of the c-Jun N-terminal kinase pathway. Rejuvenation Res. 2010;13:55-64 pubmed publisher |
| Tsika E, Moysidou M, Guo J, Cushman M, Gannon P, Sandaltzopoulos R, et al. Distinct region-specific alpha-synuclein oligomers in A53T transgenic mice: implications for neurodegeneration. J Neurosci. 2010;30:3409-18 pubmed publisher |
| Navaroli D, Melikian H. Insertion of tetracysteine motifs into dopamine transporter extracellular domains. PLoS ONE. 2010;5:e9113 pubmed publisher |
| Methner D, Mayfield R. Ethanol alters endosomal recycling of human dopamine transporters. J Biol Chem. 2010;285:10310-7 pubmed publisher |
| Graham D, Sidhu A. Mice expressing the A53T mutant form of human alpha-synuclein exhibit hyperactivity and reduced anxiety-like behavior. J Neurosci Res. 2010;88:1777-83 pubmed publisher |
| Afonso Oramas D, Cruz Muros I, Alvarez de la Rosa D, Abreu P, Giraldez T, Castro Hernandez J, et al. Dopamine transporter glycosylation correlates with the vulnerability of midbrain dopaminergic cells in Parkinson's disease. Neurobiol Dis. 2009;36:494-508 pubmed publisher |
| Furman C, Lo C, Stokes S, Esteban J, Gnegy M. Rab 11 regulates constitutive dopamine transporter trafficking and function in N2A neuroblastoma cells. Neurosci Lett. 2009;463:78-81 pubmed publisher |
| Eriksen J, Rasmussen S, Rasmussen T, Vaegter C, Cha J, Zou M, et al. Visualization of dopamine transporter trafficking in live neurons by use of fluorescent cocaine analogs. J Neurosci. 2009;29:6794-808 pubmed publisher |
| Caldero J, Brunet N, Ciutat D, Hereu M, Esquerda J. Development of microglia in the chick embryo spinal cord: implications in the regulation of motoneuronal survival and death. J Neurosci Res. 2009;87:2447-66 pubmed publisher |
| Egaña L, Cuevas R, Baust T, Parra L, Leak R, Hochendoner S, et al. Physical and functional interaction between the dopamine transporter and the synaptic vesicle protein synaptogyrin-3. J Neurosci. 2009;29:4592-604 pubmed publisher |
| Furman C, Chen R, Guptaroy B, Zhang M, Holz R, Gnegy M. Dopamine and amphetamine rapidly increase dopamine transporter trafficking to the surface: live-cell imaging using total internal reflection fluorescence microscopy. J Neurosci. 2009;29:3328-36 pubmed publisher |
| Chen R, Furman C, Zhang M, Kim M, Gereau R, Leitges M, et al. Protein kinase Cbeta is a critical regulator of dopamine transporter trafficking and regulates the behavioral response to amphetamine in mice. J Pharmacol Exp Ther. 2009;328:912-20 pubmed publisher |
| Matsumoto R, Shaikh J, Wilson L, Vedam S, Coop A. Attenuation of methamphetamine-induced effects through the antagonism of sigma (sigma) receptors: Evidence from in vivo and in vitro studies. Eur Neuropsychopharmacol. 2008;18:871-81 pubmed publisher |
| Binda F, Dipace C, Bowton E, Robertson S, Lute B, Fog J, et al. Syntaxin 1A interaction with the dopamine transporter promotes amphetamine-induced dopamine efflux. Mol Pharmacol. 2008;74:1101-8 pubmed publisher |
| Kanaan N, Kordower J, Collier T. Age-related changes in dopamine transporters and accumulation of 3-nitrotyrosine in rhesus monkey midbrain dopamine neurons: relevance in selective neuronal vulnerability to degeneration. Eur J Neurosci. 2008;27:3205-15 pubmed publisher |
| Garcia Cabezas M, Martínez Sánchez P, Sánchez González M, Garzón M, Cavada C. Dopamine innervation in the thalamus: monkey versus rat. Cereb Cortex. 2009;19:424-34 pubmed publisher |
| Delis F, Mitsacos A, Giompres P. Pharmacological characterization and anatomical distribution of the dopamine transporter in the mouse cerebellum. Cerebellum. 2008;7:242-51 pubmed publisher |
| Bianco L, Wiesinger J, Earley C, Jones B, Beard J. Iron deficiency alters dopamine uptake and response to L-DOPA injection in Sprague-Dawley rats. J Neurochem. 2008;106:205-15 pubmed publisher |
| Salahpour A, Ramsey A, Medvedev I, Kile B, Sotnikova T, Holmstrand E, et al. Increased amphetamine-induced hyperactivity and reward in mice overexpressing the dopamine transporter. Proc Natl Acad Sci U S A. 2008;105:4405-10 pubmed publisher |
| Fukakusa A, Mizoguchi H, Koike H, Nabeshima T, Takuma K, Yamada K. Tissue plasminogen activator is not involved in methamphetamine-induced neurotoxicity. J Pharmacol Sci. 2008;106:321-4 pubmed |
| Conversi D, Bonito Oliva A, Orsini C, Colelli V, Cabib S. DeltaFosB accumulation in ventro-medial caudate underlies the induction but not the expression of behavioral sensitization by both repeated amphetamine and stress. Eur J Neurosci. 2008;27:191-201 pubmed publisher |
| Cruz Muros I, Afonso Oramas D, Abreu P, Pérez Delgado M, Rodriguez M, Gonzalez Hernandez T. Aging effects on the dopamine transporter expression and compensatory mechanisms. Neurobiol Aging. 2009;30:973-86 pubmed |
| Keshet G, Tolwani R, Trejo A, Kraft P, Doyonnas R, Clayberger C, et al. Increased host neuronal survival and motor function in BMT Parkinsonian mice: involvement of immunosuppression. J Comp Neurol. 2007;504:690-701 pubmed |
| Adkins E, Samuvel D, Fog J, Eriksen J, Jayanthi L, Vaegter C, et al. Membrane mobility and microdomain association of the dopamine transporter studied with fluorescence correlation spectroscopy and fluorescence recovery after photobleaching. Biochemistry. 2007;46:10484-97 pubmed |
| Bolan E, Kivell B, Jaligam V, Oz M, Jayanthi L, Han Y, et al. D2 receptors regulate dopamine transporter function via an extracellular signal-regulated kinases 1 and 2-dependent and phosphoinositide 3 kinase-independent mechanism. Mol Pharmacol. 2007;71:1222-32 pubmed |
| Garcia Cabezas M, Rico B, Sánchez González M, Cavada C. Distribution of the dopamine innervation in the macaque and human thalamus. Neuroimage. 2007;34:965-84 pubmed |
| Garzón M, Pickel V. Subcellular distribution of M2 muscarinic receptors in relation to dopaminergic neurons of the rat ventral tegmental area. J Comp Neurol. 2006;498:821-39 pubmed |
| Salahpour A, Medvedev I, Beaulieu J, Gainetdinov R, Caron M. Local knockdown of genes in the brain using small interfering RNA: a phenotypic comparison with knockout animals. Biol Psychiatry. 2007;61:65-9 pubmed |
| Maiya R, Ponomarev I, Linse K, Harris R, Mayfield R. Defining the dopamine transporter proteome by convergent biochemical and in silico analyses. Genes Brain Behav. 2007;6:97-106 pubmed |
| Yamaguchi H, Kajitani K, Dan Y, Furuichi M, Ohno M, Sakumi K, et al. MTH1, an oxidized purine nucleoside triphosphatase, protects the dopamine neurons from oxidative damage in nucleic acids caused by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Cell Death Differ. 2006;13:551-63 pubmed |
| Sánchez González M, Garcia Cabezas M, Rico B, Cavada C. The primate thalamus is a key target for brain dopamine. J Neurosci. 2005;25:6076-83 pubmed |
| López Pérez S, Vergara P, Ventura Valenzuela J, Ureña Guerrero M, Segovia J, Beas Zarate C. Modification of dopaminergic markers expression in the striatum by neonatal exposure to glutamate during development. Int J Dev Neurosci. 2005;23:335-42 pubmed |
| Ukairo O, Bondi C, Newman A, Kulkarni S, Kozikowski A, Pan S, et al. Recognition of benztropine by the dopamine transporter (DAT) differs from that of the classical dopamine uptake inhibitors cocaine, methylphenidate, and mazindol as a function of a DAT transmembrane 1 aspartic acid residue. J Pharmacol Exp Ther. 2005;314:575-83 pubmed |
| Cyr M, Caron M, Johnson G, Laakso A. Magnetic resonance imaging at microscopic resolution reveals subtle morphological changes in a mouse model of dopaminergic hyperfunction. Neuroimage. 2005;26:83-90 pubmed |
| Osborne P, Halliday G, Cooper H, Keast J. Localization of immunoreactivity for deleted in colorectal cancer (DCC), the receptor for the guidance factor netrin-1, in ventral tier dopamine projection pathways in adult rodents. Neuroscience. 2005;131:671-81 pubmed |
| Koike K, Hashimoto K, Fukami G, Okamura N, Zhang L, Ohgake S, et al. The immunophilin ligand FK506 protects against methamphetamine-induced dopaminergic neurotoxicity in mouse striatum. Neuropharmacology. 2005;48:391-7 pubmed |
| Mori A, Ohashi S, Nakai M, Moriizumi T, Mitsumoto Y. Neural mechanisms underlying motor dysfunction as detected by the tail suspension test in MPTP-treated C57BL/6 mice. Neurosci Res. 2005;51:265-74 pubmed |
| Johnson L, Guptaroy B, Lund D, Shamban S, Gnegy M. Regulation of amphetamine-stimulated dopamine efflux by protein kinase C beta. J Biol Chem. 2005;280:10914-9 pubmed |
