product summary
company name :
EMD Millipore
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
product type :
antibody
product name :
MAP2A, 2B, 2C Antibody, clone HM-2
catalog :
MAB364
quantity :
100 µL
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
HM-2

The same clone is also sold as:
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 35
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 2f
Khrimian L, Obri A, Ramos Brossier M, Rousseaud A, Moriceau S, Nicot A, et al. Gpr158 mediates osteocalcin's regulation of cognition. J Exp Med. 2017;214:2859-2873 pubmed publisher
  • immunocytochemistry; mouse; 1:500; fig 5a
Achuta V, Grym H, Putkonen N, Louhivuori V, Kärkkäinen V, Koistinaho J, et al. Metabotropic glutamate receptor 5 responses dictate differentiation of neural progenitors to NMDA-responsive cells in fragile X syndrome. Dev Neurobiol. 2017;77:438-453 pubmed publisher
  • western blot; mouse; 1:500; fig s5b
He W, Bai G, Zhou H, Wei N, White N, Lauer J, et al. CMT2D neuropathy is linked to the neomorphic binding activity of glycyl-tRNA synthetase. Nature. 2015;526:710-4 pubmed publisher
  • immunohistochemistry; mouse; 1:1000
Mao M, Montgomery J, Kubke M, Thorne P. The Structural Development of the Mouse Dorsal Cochlear Nucleus. J Assoc Res Otolaryngol. 2015;16:473-86 pubmed publisher
  • immunohistochemistry; mouse
Rousseaud A, Delépine C, Nectoux J, Billuart P, Bienvenu T. Differential Expression and Regulation of Brain-Derived Neurotrophic Factor (BDNF) mRNA Isoforms in Brain Cells from Mecp2(308/y) Mouse Model. J Mol Neurosci. 2015;56:758-67 pubmed publisher
  • immunocytochemistry; mouse
Louhivuori L, Jansson L, Turunen P, Jäntti M, Nordström T, Louhivuori V, et al. Transient receptor potential channels and their role in modulating radial glial-neuronal interaction: a signaling pathway involving mGluR5. Stem Cells Dev. 2015;24:701-13 pubmed publisher
Molgaard S, Ulrichsen M, Boggild S, Holm M, Vaegter C, Nyengaard J, et al. Immunohistochemical visualization of mouse interneuron subtypes. F1000Res. 2014;3:242 pubmed publisher
Edgington R, Thalhammer A, Welch J, Bongrain A, Bergonzo P, Scorsone E, et al. Patterned neuronal networks using nanodiamonds and the effect of varying nanodiamond properties on neuronal adhesion and outgrowth. J Neural Eng. 2013;10:056022 pubmed publisher
Oku S, Takahashi N, Fukata Y, Fukata M. In silico screening for palmitoyl substrates reveals a role for DHHC1/3/10 (zDHHC1/3/11)-mediated neurochondrin palmitoylation in its targeting to Rab5-positive endosomes. J Biol Chem. 2013;288:19816-29 pubmed publisher
Kuszczyk M, Sanchez S, Pankiewicz J, Kim J, Duszczyk M, Guridi M, et al. Blocking the interaction between apolipoprotein E and A? reduces intraneuronal accumulation of A? and inhibits synaptic degeneration. Am J Pathol. 2013;182:1750-68 pubmed publisher
Jansson L, Louhivuori L, Wigren H, Nordström T, Louhivuori V, Castrén M, et al. Effect of glutamate receptor antagonists on migrating neural progenitor cells. Eur J Neurosci. 2013;37:1369-82 pubmed publisher
Ceci M, Pedraza M, De Carlos J. The embryonic septum and ventral pallium, new sources of olfactory cortex cells. PLoS ONE. 2012;7:e44716 pubmed publisher
Mo Y, Williams C, Miller C. DENN/MADD/IG20 alternative splicing changes and cell death in Alzheimer's disease. J Mol Neurosci. 2012;48:97-110 pubmed publisher
Krajewska M, You Z, Rong J, Kress C, Huang X, Yang J, et al. Neuronal deletion of caspase 8 protects against brain injury in mouse models of controlled cortical impact and kainic acid-induced excitotoxicity. PLoS ONE. 2011;6:e24341 pubmed publisher
Takeuchi H, Mizoguchi H, Doi Y, Jin S, Noda M, Liang J, et al. Blockade of gap junction hemichannel suppresses disease progression in mouse models of amyotrophic lateral sclerosis and Alzheimer's disease. PLoS ONE. 2011;6:e21108 pubmed publisher
Zhuang W, Li B, Long L, Chen L, Huang Q, Liang Z. Induction of autophagy promotes differentiation of glioma-initiating cells and their radiosensitivity. Int J Cancer. 2011;129:2720-31 pubmed publisher
Bolliger M, Martinelli D, Sudhof T. The cell-adhesion G protein-coupled receptor BAI3 is a high-affinity receptor for C1q-like proteins. Proc Natl Acad Sci U S A. 2011;108:2534-9 pubmed publisher
Barak B, Williams A, Bielopolski N, Gottfried I, Okun E, Brown M, et al. Tomosyn expression pattern in the mouse hippocampus suggests both presynaptic and postsynaptic functions. Front Neuroanat. 2010;4:149 pubmed publisher
Griffin G, Ferri Kolwicz S, Reyes B, Van Bockstaele E, Flanagan Cato L. Ovarian hormone-induced reorganization of oxytocin-labeled dendrites and synapses lateral to the hypothalamic ventromedial nucleus in female rats. J Comp Neurol. 2010;518:4531-45 pubmed publisher
Kocherhans S, Madhusudan A, Doehner J, Breu K, Nitsch R, Fritschy J, et al. Reduced Reelin expression accelerates amyloid-beta plaque formation and tau pathology in transgenic Alzheimer's disease mice. J Neurosci. 2010;30:9228-40 pubmed publisher
Edwards D, Das M, Molnar P, Hickman J. Addition of glutamate to serum-free culture promotes recovery of electrical activity in adult hippocampal neurons in vitro. J Neurosci Methods. 2010;190:155-63 pubmed publisher
Ceci M, López Mascaraque L, De Carlos J. The influence of the environment on Cajal-Retzius cell migration. Cereb Cortex. 2010;20:2348-60 pubmed publisher
Hawthorne A, Wylie C, Landmesser L, Deneris E, Silver J. Serotonergic neurons migrate radially through the neuroepithelium by dynamin-mediated somal translocation. J Neurosci. 2010;30:420-30 pubmed publisher
Thalhammer A, Edgington R, Cingolani L, Schoepfer R, Jackman R. The use of nanodiamond monolayer coatings to promote the formation of functional neuronal networks. Biomaterials. 2010;31:2097-104 pubmed publisher
Macias M, Nowicka D, Czupryn A, Sulejczak D, Skup M, Skangiel Kramska J, et al. Exercise-induced motor improvement after complete spinal cord transection and its relation to expression of brain-derived neurotrophic factor and presynaptic markers. BMC Neurosci. 2009;10:144 pubmed publisher
Hryciw T, MacDonald J, Phillips R, Seah C, Pasternak S, Meakin S. The fibroblast growth factor receptor substrate 3 adapter is a developmentally regulated microtubule-associated protein expressed in migrating and differentiated neurons. J Neurochem. 2010;112:924-39 pubmed publisher
Kathleen Baxter K, Uittenbogaard M, Yoon J, Chiaramello A. The neurogenic basic helix-loop-helix transcription factor NeuroD6 concomitantly increases mitochondrial mass and regulates cytoskeletal organization in the early stages of neuronal differentiation. ASN Neuro. 2009;1: pubmed publisher
Madhusudan A, Sidler C, Knuesel I. Accumulation of reelin-positive plaques is accompanied by a decline in basal forebrain projection neurons during normal aging. Eur J Neurosci. 2009;30:1064-76 pubmed publisher
Kollins K, Hu J, Bridgman P, Huang Y, Gallo G. Myosin-II negatively regulates minor process extension and the temporal development of neuronal polarity. Dev Neurobiol. 2009;69:279-98 pubmed publisher
Das M, Bhargava N, Bhalkikar A, Kang J, Hickman J. Temporal neurotransmitter conditioning restores the functional activity of adult spinal cord neurons in long-term culture. Exp Neurol. 2008;209:171-80 pubmed
Ying S, Jia F, Abbas S, Hofmann F, Ludwig A, Goldstein P. Dendritic HCN2 channels constrain glutamate-driven excitability in reticular thalamic neurons. J Neurosci. 2007;27:8719-32 pubmed
Li Q, Hosaka N, Cui W, Wang X, Cui Y, Cui Y, et al. Lin(-)CD34(-) bone marrow cells from adult mice can differentiate into neural-like cells. Neurosci Lett. 2006;408:51-6 pubmed
Stadlbauer A, Ganslandt O, Buslei R, Hammen T, Gruber S, Moser E, et al. Gliomas: histopathologic evaluation of changes in directionality and magnitude of water diffusion at diffusion-tensor MR imaging. Radiology. 2006;240:803-10 pubmed
Kamada H, Hayashi T, Sato K, Iwai M, Nagano I, Shoji M, et al. Up-regulation of low-density lipoprotein receptor expression in the ischemic core and the peri-ischemic area after transient MCA occlusion in rats. Brain Res Mol Brain Res. 2005;134:181-8 pubmed
Nagotani S, Hayashi T, Sato K, Zhang W, Deguchi K, Nagano I, et al. Reduction of cerebral infarction in stroke-prone spontaneously hypertensive rats by statins associated with amelioration of oxidative stress. Stroke. 2005;36:670-2 pubmed
product information
Catalog Number :
MAB364
Subcategory :
Neuroscience
Product Name :
Anti-MAP2A, 2B, 2C Antibody, clone HM-2
Product Type :
Antibodies
Clonality :
Monoclonal Antibody
Gene ID :
P11137
Host Name :
Mouse
Antigen :
MAP2A
Clone :
HM-2
Conjugate :
Ascites
Isotype :
IgG1
Product Description :
Anti-MAP2A, 2B, 2C Antibody, clone HM-2
Cross Reactivity :
Bovine;Chicken;Human;Mouse;Rat;Quail
Immunogen :
Rat brain microtubule-associated protein.
Specificity :
Shows selective staining of dendritic trees throughout the brain in immunohistochemical staining of brain tissue. In perkinje neurons, staining is restricted to the dendrites distal to the initial dendrite segment. No staining of cell body in mature Perkinje cells but strong staining of cell bodies of developing Perkinje cells from neonatal rats. No detectable staining of axons or non-neuronal cells. Reacts specifically with all forms of MAP2 (MAP2a ~280 kDa, MAP2b ~280 kDa and MAP2c ~70 kDa) as determined by immunoblot. No cross-reactivity observed to other MAPs or tubulin.
Package Size :
100 µL
Uses :
Western Blotting;Immunohistochemistry
Storage :
Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
more info or order :
company information
EMD Millipore
290 Concord Road
Billerica, Massachusetts 01821
bioscienceshelp@emdchemical.com
https://www.emdmillipore.com
888-854-3417
headquarters: United States
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

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