This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
EMD Millipore
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
product type :
antibody
product name :
Glial Fibrillary Acidic Protein Antibody, clone GA5
catalog :
MAB360
quantity :
100 µL
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
GA5

The same clone is also sold as:
reactivity :
tiger salamander, baboons, guinea pig, African green monkey, human, mouse, rat, dogs, chicken, bovine, zebrafish , Xenopus laevis, rhesus macaque
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, immunohistochemistry - free floating section
citations: 506
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:1000; loading ...; fig 5a
Kosuge Y, Kaneko E, Nango H, Miyagishi H, Ishige K, Ito Y. Bidens pilosa Extract Administered after Symptom Onset Attenuates Glial Activation, Improves Motor Performance, and Prolongs Survival in a Mouse Model of Amyotrophic Lateral Sclerosis. Oxid Med Cell Longev. 2020;2020:1020673 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:1000; loading ...; fig 3a
Dause T, KIRBY E. Poor Concordance of Floxed Sequence Recombination in Single Neural Stem Cells: Implications for Cell Autonomous Studies. Eneuro. 2020;7: pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:1000; loading ...; fig 4e
  • western blot; mouse; 1:1000; loading ...; fig 4d
Wei Y, Lu M, Mei M, Wang H, Han Z, Chen M, et al. Pyridoxine induces glutathione synthesis via PKM2-mediated Nrf2 transactivation and confers neuroprotection. Nat Commun. 2020;11:941 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:1000; loading ...; fig 3b
Daun K, Fuchigami T, Koyama N, Maruta N, Ikenaka K, Hitoshi S. Early Maternal and Social Deprivation Expands Neural Stem Cell Population Size and Reduces Hippocampus/Amygdala-Dependent Fear Memory. Front Neurosci. 2020;14:22 pubmed publisher
  • immunocytochemistry; mouse; 1:500; loading ...; fig 1g1
Chen F, Liu X, Chen Y, Liu J, Lu H, Wang W, et al. Sphere-induced reprogramming of RPE cells into dual-potential RPE stem-like cells. EBioMedicine. 2020;52:102618 pubmed publisher
  • western blot; rat; 1:10,000; loading ...; fig 1a, 2b
Zhou L, Shao C, Xie Y, Wang N, Xu S, Luo B, et al. Gab1 mediates PDGF signaling and is essential to oligodendrocyte differentiation and CNS myelination. elife. 2020;9: pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:1000; loading ...; fig 3b
  • immunohistochemistry - paraffin section; mouse; 1:1000; loading ...; fig 4a
Zhang R, Liu Y, Chen Y, Li Q, Marshall C, Wu T, et al. Aquaporin 4 deletion exacerbates brain impairments in a mouse model of chronic sleep disruption. CNS Neurosci Ther. 2020;26:228-239 pubmed publisher
  • immunohistochemistry - frozen section; human; loading ...; fig s9d
Sun A, Yuan Q, Fukuda M, Yu W, Yan H, Lim G, et al. Potassium channel dysfunction in human neuronal models of Angelman syndrome. Science. 2019;366:1486-1492 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:1000; loading ...; fig 9a
Upadhya D, Kodali M, Gitaí D, Castro O, Zanirati G, Upadhya R, et al. A Model of Chronic Temporal Lobe Epilepsy Presenting Constantly Rhythmic and Robust Spontaneous Seizures, Co-morbidities and Hippocampal Neuropathology. Aging Dis. 2019;10:915-936 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:400; loading ...; fig 3a
Grimaldi A, Pediconi N, Oieni F, Pizzarelli R, Rosito M, Giubettini M, et al. Neuroinflammatory Processes, A1 Astrocyte Activation and Protein Aggregation in the Retina of Alzheimer's Disease Patients, Possible Biomarkers for Early Diagnosis. Front Neurosci. 2019;13:925 pubmed publisher
  • immunohistochemistry - frozen section; human; 1:1500; loading ...; fig 4c
Hodge R, Bakken T, Miller J, Smith K, Barkan E, Graybuck L, et al. Conserved cell types with divergent features in human versus mouse cortex. Nature. 2019;573:61-68 pubmed publisher
  • immunohistochemistry - free floating section; mouse; 1:200; loading ...; fig 6a
  • immunohistochemistry; mouse; 1:200; loading ...; fig 6c
  • western blot; mouse; 1:1000; loading ...; fig 7a
Duan W, Guo M, Yi L, Zhang J, Bi Y, Liu Y, et al. Deletion of Tbk1 disrupts autophagy and reproduces behavioral and locomotor symptoms of FTD-ALS in mice. Aging (Albany NY). 2019;11:2457-2476 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:500; loading ...; fig s4b
  • immunocytochemistry; mouse; 1:500; loading ...; fig 2e
Wheeler M, Jaronen M, Covacu R, Zandee S, Scalisi G, Rothhammer V, et al. Environmental Control of Astrocyte Pathogenic Activities in CNS Inflammation. Cell. 2019;176:581-596.e18 pubmed publisher
  • immunohistochemistry; mouse; 1:1000; loading ...; fig 5a
Wu R, Li A, Sun B, Sun J, Zhang J, Zhang T, et al. A novel m6A reader Prrc2a controls oligodendroglial specification and myelination. Cell Res. 2019;29:23-41 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 1b
Webster K, Sun M, Crack P, O Brien T, Shultz S, Semple B. Age-dependent release of high-mobility group box protein-1 and cellular neuroinflammation after traumatic brain injury in mice. J Comp Neurol. 2019;527:1102-1117 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:500; loading ...; fig 3c
López Erauskin J, Tadokoro T, Baughn M, Myers B, McAlonis Downes M, Chillon Marinas C, et al. ALS/FTD-Linked Mutation in FUS Suppresses Intra-axonal Protein Synthesis and Drives Disease Without Nuclear Loss-of-Function of FUS. Neuron. 2018;100:816-830.e7 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:1000; loading ...; fig 4b
Driessen T, Zhao C, Saenz M, Stevenson S, Owada Y, Gammie S. Down-regulation of fatty acid binding protein 7 (Fabp7) is a hallmark of the postpartum brain. J Chem Neuroanat. 2018;92:92-101 pubmed publisher
  • immunocytochemistry; human; 1:50; loading ...; fig s2
Tseligka E, Sobo K, Stoppini L, Cagno V, Abdul F, Piuz I, et al. A VP1 mutation acquired during an enterovirus 71 disseminated infection confers heparan sulfate binding ability and modulates ex vivo tropism. PLoS Pathog. 2018;14:e1007190 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 2s2c
Kaczmarek Hájek K, Zhang J, Kopp R, Grosche A, Rissiek B, Saul A, et al. Re-evaluation of neuronal P2X7 expression using novel mouse models and a P2X7-specific nanobody. elife. 2018;7: pubmed publisher
  • immunohistochemistry - free floating section; mouse; 1:1000; loading ...; fig 2c
Bayguinov P, Ma Y, Gao Y, Zhao X, Jackson M. Imaging Voltage in Genetically Defined Neuronal Subpopulations with a Cre Recombinase-Targeted Hybrid Voltage Sensor. J Neurosci. 2017;37:9305-9319 pubmed publisher
  • immunohistochemistry; guinea pig; 1:200; loading ...; fig 2c
Hatakeyama J, Sato H, Shimamura K. Developing guinea pig brain as a model for cortical folding. Dev Growth Differ. 2017;59:286-301 pubmed publisher
  • immunocytochemistry; mouse; 1:1000; loading ...; fig 7e
Jin X, Yu Z, Chen F, Lu G, Ding X, Xie L, et al. Neuronal Nitric Oxide Synthase in Neural Stem Cells Induces Neuronal Fate Commitment via the Inhibition of Histone Deacetylase 2. Front Cell Neurosci. 2017;11:66 pubmed publisher
  • western blot; mouse; loading ...; fig 2d
Po A, Begalli F, Abballe L, Alfano V, Besharat Z, Catanzaro G, et al. ?-Arrestin1/miR-326 Transcription Unit Is Epigenetically Regulated in Neural Stem Cells Where It Controls Stemness and Growth Arrest. Stem Cells Int. 2017;2017:5274171 pubmed publisher
  • immunohistochemistry - frozen section; human; 1:1000; fig 5d
Liddelow S, Guttenplan K, Clarke L, Bennett F, Bohlen C, Schirmer L, et al. Neurotoxic reactive astrocytes are induced by activated microglia. Nature. 2017;541:481-487 pubmed publisher
  • immunocytochemistry; human; 1:200; fig 4o
Liu W, Sun Y, He Y, Zhang H, Zheng Y, Yao Y, et al. IL-1? impedes the chondrogenic differentiation of synovial fluid mesenchymal stem cells in the human temporomandibular joint. Int J Mol Med. 2017;39:317-326 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:400; loading ...; fig 7c
Perland E, Hellsten S, Lekholm E, Eriksson M, Arapi V, Fredriksson R. The Novel Membrane-Bound Proteins MFSD1 and MFSD3 are Putative SLC Transporters Affected by Altered Nutrient Intake. J Mol Neurosci. 2017;61:199-214 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:1000; loading ...; fig 3a
Nagahara Y, Shimazawa M, Ohuchi K, Ito J, Takahashi H, Tsuruma K, et al. GPNMB ameliorates mutant TDP-43-induced motor neuron cell death. J Neurosci Res. 2017;95:1647-1665 pubmed publisher
  • immunohistochemistry - paraffin section; baboons; 1:300; loading ...; fig 4
Pérez Ibave D, González Alvarez R, de La Luz Martinez Fierro M, Ruiz Ayma G, Luna Muñoz M, Martínez de Villarreal L, et al. Olfactomedin-like 2 A and B (OLFML2A and OLFML2B) expression profile in primates (human and baboon). Biol Res. 2016;49:44 pubmed
  • immunohistochemistry - free floating section; rat; 1:1000; loading ...; tbl 2
Shepherd D, Tsai S, O Brien T, Farrer R, Kartje G. Anti-Nogo-A Immunotherapy Does Not Alter Hippocampal Neurogenesis after Stroke in Adult Rats. Front Neurosci. 2016;10:467 pubmed
  • immunohistochemistry; rat; 1:10,000; loading ...; fig s2d
Teo J, Morris M, Jones N. Maternal obesity increases inflammation and exacerbates damage following neonatal hypoxic-ischaemic brain injury in rats. Brain Behav Immun. 2017;63:186-196 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:50; loading ...; fig 2d
Huang L, Cao W, Deng Y, Zhu G, Han Y, Zeng H. Hypertonic saline alleviates experimentally induced cerebral oedema through suppression of vascular endothelial growth factor and its receptor VEGFR2 expression in astrocytes. BMC Neurosci. 2016;17:64 pubmed
  • immunohistochemistry - frozen section; rat; 1:100; loading ...; fig 5
  • western blot; rat; 1:2500; loading ...
Cudré Cung H, Zavadakova P, Do Vale Pereira S, Remacle N, Henry H, Ivanisevic J, et al. Ammonium accumulation is a primary effect of 2-methylcitrate exposure in an in vitro model for brain damage in methylmalonic aciduria. Mol Genet Metab. 2016;119:57-67 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:1000; fig 2e
  • western blot; mouse; 1:2000; fig 1b
Choi S, Roh D, Yoon S, Kwon S, Choi H, Han H, et al. Astrocyte sigma-1 receptors modulate connexin 43 expression leading to the induction of below-level mechanical allodynia in spinal cord injured mice. Neuropharmacology. 2016;111:34-46 pubmed publisher
  • immunohistochemistry; mouse; fig 2
Du R, Wu F, Lu M, Shu X, Ding J, Wu G, et al. Uncoupling protein 2 modulation of the NLRP3 inflammasome in astrocytes and its implications in depression. Redox Biol. 2016;9:178-187 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig s2g
Portillo J, Lopez Corcino Y, Miao Y, Tang J, Sheibani N, Kern T, et al. CD40 in Retinal Müller Cells Induces P2X7-Dependent Cytokine Expression in Macrophages/Microglia in Diabetic Mice and Development of Early Experimental Diabetic Retinopathy. Diabetes. 2017;66:483-493 pubmed publisher
  • immunohistochemistry; rat; 1:5000
Duggett N, Griffiths L, McKenna O, De Santis V, Yongsanguanchai N, Mokori E, et al. Oxidative stress in the development, maintenance and resolution of paclitaxel-induced painful neuropathy. Neuroscience. 2016;333:13-26 pubmed publisher
  • immunocytochemistry; mouse; 1:500; loading ...; fig 3d
  • western blot; mouse; 1:1000; loading ...; fig 3f
Huang Z, Hu J, Pan J, Wang Y, Hu G, Zhou J, et al. YAP stabilizes SMAD1 and promotes BMP2-induced neocortical astrocytic differentiation. Development. 2016;143:2398-409 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 2-s1
Forsberg D, Horn Z, Tserga E, Smedler E, Silberberg G, Shvarev Y, et al. CO2-evoked release of PGE2 modulates sighs and inspiration as demonstrated in brainstem organotypic culture. elife. 2016;5: pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 5b
  • western blot; mouse; 1:1000; loading ...; fig 6a
Yoo S, Motari M, Schnaar R. Agenesis of the corpus callosum in Nogo receptor deficient mice. J Comp Neurol. 2017;525:291-301 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:800; fig 6
Perland E, Lekholm E, Eriksson M, Bagchi S, Arapi V, Fredriksson R. The Putative SLC Transporters Mfsd5 and Mfsd11 Are Abundantly Expressed in the Mouse Brain and Have a Potential Role in Energy Homeostasis. PLoS ONE. 2016;11:e0156912 pubmed publisher
  • immunohistochemistry - free floating section; rat; 1:1200; fig 3
Morales I, Sánchez A, Rodriguez Sabate C, Rodriguez M. The astrocytic response to the dopaminergic denervation of the striatum. J Neurochem. 2016;139:81-95 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:1000; fig 1
Reinhard J, Kriz A, Galic M, Angliker N, Rajalu M, Vogt K, et al. The calcium sensor Copine-6 regulates spine structural plasticity and learning and memory. Nat Commun. 2016;7:11613 pubmed publisher
  • immunocytochemistry; human; 1:800; fig 3
Rosiak K, Smolarz M, Stec W, Peciak J, Grzela D, Winiecka Klimek M, et al. IDH1R132H in Neural Stem Cells: Differentiation Impaired by Increased Apoptosis. PLoS ONE. 2016;11:e0154726 pubmed publisher
  • western blot; mouse; 1:2000; fig s6
Bouvier D, Jones E, Quesseveur G, Davoli M, A Ferreira T, Quirion R, et al. High Resolution Dissection of Reactive Glial Nets in Alzheimer's Disease. Sci Rep. 2016;6:24544 pubmed publisher
  • western blot; mouse; 1:5000; fig 1
Almad A, Doreswamy A, Gross S, Richard J, Huo Y, Haughey N, et al. Connexin 43 in astrocytes contributes to motor neuron toxicity in amyotrophic lateral sclerosis. Glia. 2016;64:1154-69 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:400; loading ...; fig 7j
Chtarto A, Humbert Claude M, Bockstael O, Das A, Boutry S, Breger L, et al. A regulatable AAV vector mediating GDNF biological effects at clinically-approved sub-antimicrobial doxycycline doses. Mol Ther Methods Clin Dev. 2016;5:16027 pubmed publisher
  • immunohistochemistry; rat; 1:100; fig 2b
Isotani A, Yamagata K, Okabe M, Ikawa M. Generation of Hprt-disrupted rat through mouse?rat ES chimeras. Sci Rep. 2016;6:24215 pubmed publisher
  • immunocytochemistry; mouse; 1:200
Du C, Duan Y, Wei W, Cai Y, Chai H, Lv J, et al. Kappa opioid receptor activation alleviates experimental autoimmune encephalomyelitis and promotes oligodendrocyte-mediated remyelination. Nat Commun. 2016;7:11120 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:1000; fig 1g
  • immunocytochemistry; mouse; 1:1000; fig 1l
Nagao M, Ogata T, Sawada Y, Gotoh Y. Zbtb20 promotes astrocytogenesis during neocortical development. Nat Commun. 2016;7:11102 pubmed publisher
  • immunocytochemistry; rat; 1:500; fig 5
Cui Y, Han J, Xiao Z, Chen T, Wang B, Chen B, et al. The miR-20-Rest-Wnt signaling axis regulates neural progenitor cell differentiation. Sci Rep. 2016;6:23300 pubmed publisher
  • immunocytochemistry; mouse; loading ...; fig 3e
  • western blot; mouse; loading ...; fig 3c-d
Wang G, Liu X, Gaertig M, Li S, Li X. Ablation of huntingtin in adult neurons is nondeleterious but its depletion in young mice causes acute pancreatitis. Proc Natl Acad Sci U S A. 2016;113:3359-64 pubmed publisher
  • immunocytochemistry; rat; fig 1
Zhu Y, Gao W, Zhang Y, Jia F, Zhang H, Liu Y, et al. Astrocyte-derived phosphatidic acid promotes dendritic branching. Sci Rep. 2016;6:21096 pubmed publisher
  • western blot; human; fig 2
Catanzaro G, Besharat Z, Garg N, Ronci M, Pieroni L, Miele E, et al. MicroRNAs-Proteomic Networks Characterizing Human Medulloblastoma-SLCs. Stem Cells Int. 2016;2016:2683042 pubmed publisher
  • immunohistochemistry - free floating section; rat; 1:1000; fig 6
  • western blot; rat; 1:400; fig 6
Lee Kubli C, Ingves M, Henry K, Shiao R, Collyer E, Tuszynski M, et al. Analysis of the behavioral, cellular and molecular characteristics of pain in severe rodent spinal cord injury. Exp Neurol. 2016;278:91-104 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:800; loading ...; fig 4a
  • western blot; rat; 1:60,000; loading ...; fig 2b
Najafi E, Stoodley M, Bilston L, Hemley S. Inwardly rectifying potassium channel 4.1 expression in post-traumatic syringomyelia. Neuroscience. 2016;317:23-35 pubmed publisher
  • immunohistochemistry - paraffin section; rat; fig 5
Fang M, Yuan Y, Rangarajan P, Lu J, Wu Y, Wang H, et al. Scutellarin regulates microglia-mediated TNC1 astrocytic reaction and astrogliosis in cerebral ischemia in the adult rats. BMC Neurosci. 2015;16:84 pubmed publisher
  • immunocytochemistry; mouse; 1:1000
Mircsof D, Langouët M, Rio M, Moutton S, Siquier Pernet K, Bole Feysot C, et al. Mutations in NONO lead to syndromic intellectual disability and inhibitory synaptic defects. Nat Neurosci. 2015;18:1731-6 pubmed publisher
  • immunohistochemistry; tiger salamander; 1:400; fig 7
Rodrigo Albors A, Tazaki A, Rost F, Nowoshilow S, Chara O, Tanaka E. Planar cell polarity-mediated induction of neural stem cell expansion during axolotl spinal cord regeneration. elife. 2015;4:e10230 pubmed publisher
  • immunocytochemistry; human; 1:400; fig 6
Winiecka Klimek M, Smolarz M, Walczak M, Zieba J, Hulas Bigoszewska K, Kmieciak B, et al. SOX2 and SOX2-MYC Reprogramming Process of Fibroblasts to the Neural Stem Cells Compromised by Senescence. PLoS ONE. 2015;10:e0141688 pubmed publisher
  • immunocytochemistry; human; 1:500; fig 2
Bonaventura G, Chamayou S, Liprino A, Guglielmino A, Fichera M, Caruso M, et al. Different Tissue-Derived Stem Cells: A Comparison of Neural Differentiation Capability. PLoS ONE. 2015;10:e0140790 pubmed publisher
  • immunocytochemistry; human; fig 1
Telias M, Mayshar Y, Amit A, Ben Yosef D. Molecular mechanisms regulating impaired neurogenesis of fragile X syndrome human embryonic stem cells. Stem Cells Dev. 2015;24:2353-65 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:500
James R, Hillis J, Adorján I, Gration B, Mundim M, Iqbal A, et al. Loss of galectin-3 decreases the number of immune cells in the subventricular zone and restores proliferation in a viral model of multiple sclerosis. Glia. 2016;64:105-21 pubmed publisher
  • immunohistochemistry - frozen section; mouse; fig 3
Rolyan H, Tyurina Y, Hernandez M, Amoscato A, Sparvero L, Nmezi B, et al. Defects of Lipid Synthesis Are Linked to the Age-Dependent Demyelination Caused by Lamin B1 Overexpression. J Neurosci. 2015;35:12002-17 pubmed publisher
  • immunohistochemistry; mouse; 1:100
Angliker N, Burri M, Zaichuk M, Fritschy J, Rüegg M. mTORC1 and mTORC2 have largely distinct functions in Purkinje cells. Eur J Neurosci. 2015;42:2595-612 pubmed publisher
  • immunocytochemistry; human; 1:500; fig s13
Wong F, Fei J, Mora Bermúdez F, Taverna E, Haffner C, Fu J, et al. Sustained Pax6 Expression Generates Primate-like Basal Radial Glia in Developing Mouse Neocortex. PLoS Biol. 2015;13:e1002217 pubmed publisher
  • immunohistochemistry - paraffin section; human; fig 2
Noell S, Fallier Becker P, Mack A, Hoffmeister M, Beschorner R, Ritz R. Water Channels Aquaporin 4 and -1 Expression in Subependymoma Depends on the Localization of the Tumors. PLoS ONE. 2015;10:e0131367 pubmed publisher
  • immunocytochemistry; mouse; 1:1000
Liu Y, Miao Q, Yuan J, Han S, Zhang P, Li S, et al. Ascl1 Converts Dorsal Midbrain Astrocytes into Functional Neurons In Vivo. J Neurosci. 2015;35:9336-55 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:200
  • western blot; rat; 1:1000
Tang H, Hua F, Wang J, Yousuf S, Atif F, Sayeed I, et al. Progesterone and vitamin D combination therapy modulates inflammatory response after traumatic brain injury. Brain Inj. 2015;29:1165-1174 pubmed publisher
  • immunocytochemistry; rat; 1:100
Tang N, Lyu D, Liu T, Chen F, Jing S, Hao T, et al. Different Effects of p52SHC1 and p52SHC3 on the Cell Cycle of Neurons and Neural Stem Cells. J Cell Physiol. 2016;231:172-80 pubmed publisher
  • immunocytochemistry; mouse; 1:400; loading ...; tbl 1
Terzic D, Maxon J, Krevitt L, DiBartolomeo C, Goyal T, Low W, et al. Directed Differentiation of Oligodendrocyte Progenitor Cells From Mouse Induced Pluripotent Stem Cells. Cell Transplant. 2016;25:411-24 pubmed publisher
  • immunohistochemistry; mouse; fig 4
Sheean R, Weston R, Perera N, D Amico A, Nutt S, Turner B. Effect of thymic stimulation of CD4+ T cell expansion on disease onset and progression in mutant SOD1 mice. J Neuroinflammation. 2015;12:40 pubmed publisher
  • immunohistochemistry; mouse; 1:400
Orije J, Kara F, Guglielmetti C, Praet J, Van der Linden A, Ponsaerts P, et al. Longitudinal monitoring of metabolic alterations in cuprizone mouse model of multiple sclerosis using 1H-magnetic resonance spectroscopy. Neuroimage. 2015;114:128-35 pubmed publisher
  • immunohistochemistry; mouse; 1:1000; fig 5P
Watzlawik J, Kahoud R, Ng S, Painter M, Papke L, Zoecklein L, et al. Polysialic acid as an antigen for monoclonal antibody HIgM12 to treat multiple sclerosis and other neurodegenerative disorders. J Neurochem. 2015;134:865-78 pubmed publisher
  • immunocytochemistry; rat; 1:200; fig s4
Gu Q, Yu D, Hu Z, Liu X, Yang Y, Luo Y, et al. miR-26a and miR-384-5p are required for LTP maintenance and spine enlargement. Nat Commun. 2015;6:6789 pubmed publisher
  • immunohistochemistry; rat; 1:1000
Isaev D, Lushnikova I, Lunko O, Zapukhliak O, Maximyuk O, Romanov A, et al. Contribution of protease-activated receptor 1 in status epilepticus-induced epileptogenesis. Neurobiol Dis. 2015;78:68-76 pubmed publisher
  • immunohistochemistry - paraffin section; mouse
Luna Sánchez M, Díaz Casado E, Barca E, Tejada M, Montilla García Ã, Cobos E, et al. The clinical heterogeneity of coenzyme Q10 deficiency results from genotypic differences in the Coq9 gene. EMBO Mol Med. 2015;7:670-87 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:400
  • immunohistochemistry - paraffin section; human; 1:400
Bedner P, Dupper A, Hüttmann K, Muller J, Herde M, Dublin P, et al. Astrocyte uncoupling as a cause of human temporal lobe epilepsy. Brain. 2015;138:1208-22 pubmed publisher
  • immunohistochemistry; mouse; 1:100
Bouyakdan K, Taïb B, Budry L, Zhao S, Rodaros D, Neess D, et al. A novel role for central ACBP/DBI as a regulator of long-chain fatty acid metabolism in astrocytes. J Neurochem. 2015;133:253-65 pubmed publisher
  • immunohistochemistry - paraffin section; rat; 1:400
  • western blot; rat; 1:1000
Maurya S, Mishra J, Abbas S, Bandyopadhyay S. Cypermethrin Stimulates GSK3β-Dependent Aβ and p-tau Proteins and Cognitive Loss in Young Rats: Reduced HB-EGF Signaling and Downstream Neuroinflammation as Critical Regulators. Mol Neurobiol. 2016;53:968-82 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:500; fig 5
  • immunocytochemistry; mouse; 1:500; fig 4
Sathyamurthy A, Yin D, Barik A, Shen C, Bean J, Figueiredo D, et al. ERBB3-mediated regulation of Bergmann glia proliferation in cerebellar lamination. Development. 2015;142:522-32 pubmed publisher
  • immunohistochemistry; mouse; 1:500
  • immunohistochemistry; rat; 1:500
Li Y, Korgaonkar A, Swietek B, Wang J, Elgammal F, Elkabes S, et al. Toll-like receptor 4 enhancement of non-NMDA synaptic currents increases dentate excitability after brain injury. Neurobiol Dis. 2015;74:240-53 pubmed publisher
  • immunohistochemistry; mouse; 1:100
Zille M, Riabinska A, Terzi M, Balkaya M, Prinz V, Schmerl B, et al. Influence of pigment epithelium-derived factor on outcome after striatal cerebral ischemia in the mouse. PLoS ONE. 2014;9:e114595 pubmed publisher
  • immunohistochemistry; rat; 1:1000
Lazarus R, Buonora J, Jacobowitz D, Mueller G. Protein carbonylation after traumatic brain injury: cell specificity, regional susceptibility, and gender differences. Free Radic Biol Med. 2015;78:89-100 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:2000
Fuentes Santamaría V, Alvarado J, López Muñoz D, Melgar Rojas P, Gabaldón Ull M, Juiz J. Glia-related mechanisms in the anteroventral cochlear nucleus of the adult rat in response to unilateral conductive hearing loss. Front Neurosci. 2014;8:319 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:25,000; loading ...; fig s3
Baek J, Schmidt E, Viceconte N, Strandgren C, Pernold K, Richard T, et al. Expression of progerin in aging mouse brains reveals structural nuclear abnormalities without detectible significant alterations in gene expression, hippocampal stem cells or behavior. Hum Mol Genet. 2015;24:1305-21 pubmed publisher
  • immunohistochemistry - free floating section; mouse; 1:100
Heng Y, Zhou B, Harris L, Harvey T, Smith A, Horne E, et al. NFIX Regulates Proliferation and Migration Within the Murine SVZ Neurogenic Niche. Cereb Cortex. 2015;25:3758-78 pubmed publisher
  • immunohistochemistry - frozen section; human; 1:1000
Tate M, Lindquist R, Nguyen T, Sanai N, Barkovich A, Huang E, et al. Postnatal growth of the human pons: a morphometric and immunohistochemical analysis. J Comp Neurol. 2015;523:449-62 pubmed publisher
  • immunohistochemistry; rat; 1:100
Ashok A, Rai N, Tripathi S, Bandyopadhyay S. Exposure to As-, Cd-, and Pb-mixture induces Aβ, amyloidogenic APP processing and cognitive impairments via oxidative stress-dependent neuroinflammation in young rats. Toxicol Sci. 2015;143:64-80 pubmed publisher
  • immunohistochemistry - paraffin section; mouse
Kaneko M, Noguchi T, Ikegami S, Sakurai T, Kakita A, Toyoshima Y, et al. Zinc transporters ZnT3 and ZnT6 are downregulated in the spinal cords of patients with sporadic amyotrophic lateral sclerosis. J Neurosci Res. 2015;93:370-9 pubmed publisher
  • immunohistochemistry - free floating section; rat; 1:1000
Rajput P, Lyden P, Chen B, Lamb J, Pereira B, Lamb A, et al. Protease activated receptor-1 mediates cytotoxicity during ischemia using in vivo and in vitro models. Neuroscience. 2014;281:229-40 pubmed publisher
  • immunocytochemistry; rat
Zhang J, Sun X, Zheng S, Liu X, Jin J, Ren Y, et al. Myelin basic protein induces neuron-specific toxicity by directly damaging the neuronal plasma membrane. PLoS ONE. 2014;9:e108646 pubmed publisher
  • immunocytochemistry; human; 1:500; loading ...; fig 1b
Lee H, Kim K, Lim H, Choi M, Kim H, Ahn H, et al. Priming Wharton's jelly-derived mesenchymal stromal/stem cells with ROCK inhibitor improves recovery in an intracerebral hemorrhage model. J Cell Biochem. 2015;116:310-9 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:200
Berdugo Vega G, Arias Gil G, Rodriguez Niedenführ M, Davies D, Vázquez T, Pascual Font A. GFAP immunoreactivity within the rat nucleus ambiguus after laryngeal nerve injury. J Anat. 2014;225:492-501 pubmed publisher
  • western blot; mouse; 1:10,000; fig 2
Gruol D, Vo K, Bray J. Increased astrocyte expression of IL-6 or CCL2 in transgenic mice alters levels of hippocampal and cerebellar proteins. Front Cell Neurosci. 2014;8:234 pubmed publisher
  • immunohistochemistry; rat; 1:1000
Fu H, Yang T, Xiao W, Fan L, Wu Y, Terrando N, et al. Prolonged neuroinflammation after lipopolysaccharide exposure in aged rats. PLoS ONE. 2014;9:e106331 pubmed publisher
  • immunohistochemistry; rat; 1:200; fig 6
Chau M, Deveau T, Song M, Gu X, Chen D, Wei L. iPSC Transplantation increases regeneration and functional recovery after ischemic stroke in neonatal rats. Stem Cells. 2014;32:3075-87 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:200
Yarchoan M, Toledo J, Lee E, Arvanitakis Z, Kazi H, Han L, et al. Abnormal serine phosphorylation of insulin receptor substrate 1 is associated with tau pathology in Alzheimer's disease and tauopathies. Acta Neuropathol. 2014;128:679-89 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:500
Hayakawa K, Okazaki R, Morioka K, Nakamura K, Tanaka S, Ogata T. Lipopolysaccharide preconditioning facilitates M2 activation of resident microglia after spinal cord injury. J Neurosci Res. 2014;92:1647-58 pubmed publisher
  • immunohistochemistry; mouse; 1:200; fig  4
Syhr K, Kallenborn Gerhardt W, Lu R, Olbrich K, Schmitz K, Männich J, et al. Lack of effect of a P2Y6 receptor antagonist on neuropathic pain behavior in mice. Pharmacol Biochem Behav. 2014;124:389-95 pubmed publisher
  • immunohistochemistry; zebrafish ; 1:100; fig 3
Makantasi P, Dermon C. Estradiol treatment decreases cell proliferation in the neurogenic zones of adult female zebrafish (Danio rerio) brain. Neuroscience. 2014;277:306-20 pubmed publisher
  • immunocytochemistry; mouse; 1:100
Torrado E, Gomes C, Santos G, Fernandes A, Brites D, Falcão A. Directing mouse embryonic neurosphere differentiation toward an enriched neuronal population. Int J Dev Neurosci. 2014;37:94-9 pubmed publisher
  • immunocytochemistry; rat; 1:100
  • immunohistochemistry; rat; 1:100
  • western blot; rat; 1:100
Huang L, Zhu G, Deng Y, Jiang W, Fang M, Chen C, et al. Hypertonic saline alleviates cerebral edema by inhibiting microglia-derived TNF-? and IL-1?-induced Na-K-Cl Cotransporter up-regulation. J Neuroinflammation. 2014;11:102 pubmed publisher
  • immunohistochemistry; mouse; 1:400
Fallier Becker P, Vollmer J, Bauer H, Noell S, Wolburg H, Mack A. Onset of aquaporin-4 expression in the developing mouse brain. Int J Dev Neurosci. 2014;36:81-9 pubmed publisher
  • immunohistochemistry - free floating section; mouse; 1:1000
Cho S, Jeon J, Chun D, Yeo S, Kim I. Anoctamin 1 expression in the mouse auditory brainstem. Cell Tissue Res. 2014;357:563-9 pubmed publisher
  • immunocytochemistry; Xenopus laevis; 1:400
Hamilton C, Navarro Martín L, Neufeld M, Basak A, Trudeau V. Early expression of aromatase and the membrane estrogen receptor GPER in neuromasts reveals a role for estrogens in the development of the frog lateral line system. Gen Comp Endocrinol. 2014;205:242-50 pubmed publisher
  • immunohistochemistry - free floating section; rat; 1:1000
Singh R, Brewer M, Mashburn C, Lou D, Bondada V, Graham B, et al. Calpain 5 is highly expressed in the central nervous system (CNS), carries dual nuclear localization signals, and is associated with nuclear promyelocytic leukemia protein bodies. J Biol Chem. 2014;289:19383-94 pubmed publisher
  • immunocytochemistry; mouse; 1:1000
Ho V, Dallalzadeh L, Karathanasis N, Keles M, Vangala S, Grogan T, et al. GluA2 mRNA distribution and regulation by miR-124 in hippocampal neurons. Mol Cell Neurosci. 2014;61:1-12 pubmed publisher
  • western blot; mouse; 1:10000
Gruol D, Vo K, Bray J, Roberts A. CCL2-ethanol interactions and hippocampal synaptic protein expression in a transgenic mouse model. Front Integr Neurosci. 2014;8:29 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:1000
  • western blot; mouse; 1:3000
Stein L, Wozniak D, Dearborn J, Kubota S, Apte R, Izumi Y, et al. Expression of Nampt in hippocampal and cortical excitatory neurons is critical for cognitive function. J Neurosci. 2014;34:5800-15 pubmed publisher
  • immunohistochemistry; mouse; 1:500
Okuda H, Tatsumi K, Horii Hayashi N, Morita S, Okuda Yamamoto A, Imaizumi K, et al. OASIS regulates chondroitin 6-O-sulfotransferase 1 gene transcription in the injured adult mouse cerebral cortex. J Neurochem. 2014;130:612-25 pubmed publisher
  • immunohistochemistry - free floating section; human; 1:500
  • immunohistochemistry - free floating section; rhesus macaque; 1:500
Alfaro Cervello C, Cebrian Silla A, Soriano Navarro M, García Tárraga P, Matías Guiu J, Gomez Pinedo U, et al. The adult macaque spinal cord central canal zone contains proliferative cells and closely resembles the human. J Comp Neurol. 2014;522:1800-17 pubmed publisher
  • immunohistochemistry - free floating section; rat; 1:5000
  • western blot; rat; 1:2000
Xu Q, Cheong Y, He S, Tiwari V, Liu J, Wang Y, et al. Suppression of spinal connexin 43 expression attenuates mechanical hypersensitivity in rats after an L5 spinal nerve injury. Neurosci Lett. 2014;566:194-199 pubmed publisher
  • western blot; rat; 1:1000
Xu M, Yang L, Rong J, Ni Y, Gu W, Luo Y, et al. Inhibition of cysteine cathepsin B and L activation in astrocytes contributes to neuroprotection against cerebral ischemia via blocking the tBid-mitochondrial apoptotic signaling pathway. Glia. 2014;62:855-80 pubmed publisher
  • immunohistochemistry - paraffin section; mouse
García Corzo L, Luna Sánchez M, Doerrier C, Ortiz F, Escames G, Acuna Castroviejo D, et al. Ubiquinol-10 ameliorates mitochondrial encephalopathy associated with CoQ deficiency. Biochim Biophys Acta. 2014;1842:893-901 pubmed publisher
  • immunohistochemistry; mouse; 1:500
Haba R, Shintani N, Onaka Y, Kanoh T, Wang H, Takenaga R, et al. Central CRTH2, a second prostaglandin D2 receptor, mediates emotional impairment in the lipopolysaccharide and tumor-induced sickness behavior model. J Neurosci. 2014;34:2514-23 pubmed publisher
  • immunocytochemistry; rat; 1:1000
  • immunohistochemistry; rat; 1:1000
Deng Y, Xie D, Fang M, Zhu G, Chen C, Zeng H, et al. Astrocyte-derived proinflammatory cytokines induce hypomyelination in the periventricular white matter in the hypoxic neonatal brain. PLoS ONE. 2014;9:e87420 pubmed publisher
  • immunohistochemistry - frozen section; mouse
Hagiwara K, Obayashi T, Sakayori N, Yamanishi E, Hayashi R, Osumi N, et al. Molecular and cellular features of murine craniofacial and trunk neural crest cells as stem cell-like cells. PLoS ONE. 2014;9:e84072 pubmed publisher
  • immunohistochemistry; mouse; 1:10000
Balu D, Takagi S, Puhl M, Benneyworth M, Coyle J. D-serine and serine racemase are localized to neurons in the adult mouse and human forebrain. Cell Mol Neurobiol. 2014;34:419-35 pubmed publisher
  • immunohistochemistry; African green monkey; 1:100000
Samaranch L, Sebastián W, Kells A, Salegio E, Heller G, Bringas J, et al. AAV9-mediated expression of a non-self protein in nonhuman primate central nervous system triggers widespread neuroinflammation driven by antigen-presenting cell transduction. Mol Ther. 2014;22:329-337 pubmed publisher
  • immunohistochemistry; rat; 1:200
Matsumoto Y, Kanamori A, Nakamura M, Takahashi T, Nakashima I, Negi A. Sera from patients with seropositive neuromyelitis optica spectral disorders caused the degeneration of rodent optic nerve. Exp Eye Res. 2014;119:61-9 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:400
Trabalza A, Eleftheriadou I, Sgourou A, Liao T, Patsali P, Lee H, et al. Enhanced central nervous system transduction with lentiviral vectors pseudotyped with RVG/HIV-1gp41 chimeric envelope glycoproteins. J Virol. 2014;88:2877-90 pubmed publisher
  • immunocytochemistry; human
  • immunocytochemistry; rat
Muirhead G, Dev K. The expression of neuronal sorting nexin 8 (SNX8) exacerbates abnormal cholesterol levels. J Mol Neurosci. 2014;53:125-34 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:1500
ElAli A, Theriault P, Prefontaine P, Rivest S. Mild chronic cerebral hypoperfusion induces neurovascular dysfunction, triggering peripheral beta-amyloid brain entry and aggregation. Acta Neuropathol Commun. 2013;1:75 pubmed publisher
  • immunohistochemistry; mouse; 1:500
Robins S, Trudel E, Rotondi O, Liu X, Djogo T, Kryzskaya D, et al. Evidence for NG2-glia derived, adult-born functional neurons in the hypothalamus. PLoS ONE. 2013;8:e78236 pubmed publisher
  • immunohistochemistry - paraffin section; rat; 1:200
Akane H, Shiraki A, Imatanaka N, Akahori Y, Itahashi M, Abe H, et al. Glycidol induces axonopathy and aberrations of hippocampal neurogenesis affecting late-stage differentiation by exposure to rats in a framework of 28-day toxicity study. Toxicol Lett. 2014;224:424-32 pubmed publisher
  • immunocytochemistry; human
Tucker B, Mullins R, Streb L, Anfinson K, Eyestone M, Kaalberg E, et al. Patient-specific iPSC-derived photoreceptor precursor cells as a means to investigate retinitis pigmentosa. elife. 2013;2:e00824 pubmed publisher
  • immunocytochemistry; dogs
Tobias I, Brooks C, Teichroeb J, Betts D. Derivation and culture of canine embryonic stem cells. Methods Mol Biol. 2013;1074:69-83 pubmed publisher
  • immunohistochemistry - free floating section; mouse; 1:4000
  • western blot; mouse
  • immunohistochemistry - free floating section; rat; 1:4000
  • western blot; rat
Sun X, Chen B, Duan L, Xia Y, Luo Z, Wang J, et al. The proform of glia cell line-derived neurotrophic factor: a potentially biologically active protein. Mol Neurobiol. 2014;49:234-50 pubmed publisher
  • immunohistochemistry - frozen section; rat
  • immunohistochemistry - frozen section; mouse; 1:100
Gong N, Li X, Xiao Q, Wang Y. Identification of a novel spinal dorsal horn astroglial D-amino acid oxidase-hydrogen peroxide pathway involved in morphine antinociceptive tolerance. Anesthesiology. 2014;120:962-75 pubmed publisher
  • western blot; mouse; 1:2500; fig 6
Li H, Zhang N, Sun G, Ding S. Inhibition of the group I mGluRs reduces acute brain damage and improves long-term histological outcomes after photothrombosis-induced ischaemia. ASN Neuro. 2013;5:195-207 pubmed publisher
  • immunocytochemistry; rat; 1:500
  • immunohistochemistry; rat; 1:500
  • western blot; rat; 1:1000
Li X, Xiao Z, Han J, Chen L, Xiao H, Ma F, et al. Promotion of neuronal differentiation of neural progenitor cells by using EGFR antibody functionalized collagen scaffolds for spinal cord injury repair. Biomaterials. 2013;34:5107-16 pubmed publisher
  • immunohistochemistry; human; 1:200
  • western blot; human; 1:1000
Zemp F, Lun X, McKenzie B, Zhou H, Maxwell L, Sun B, et al. Treating brain tumor-initiating cells using a combination of myxoma virus and rapamycin. Neuro Oncol. 2013;15:904-20 pubmed publisher
  • immunohistochemistry - frozen section; African green monkey; 1:100000
Samaranch L, Salegio E, San Sebastián W, Kells A, Bringas J, Forsayeth J, et al. Strong cortical and spinal cord transduction after AAV7 and AAV9 delivery into the cerebrospinal fluid of nonhuman primates. Hum Gene Ther. 2013;24:526-32 pubmed publisher
  • immunohistochemistry - paraffin section; rat; 1:800
  • western blot; rat; 1:60000
Hemley S, Bilston L, Cheng S, Chan J, Stoodley M. Aquaporin-4 expression in post-traumatic syringomyelia. J Neurotrauma. 2013;30:1457-67 pubmed publisher
  • immunohistochemistry; mouse; 1:200
Wang L, Ohishi T, Akane H, Shiraki A, Itahashi M, Mitsumori K, et al. Reversible effect of developmental exposure to chlorpyrifos on late-stage neurogenesis in the hippocampal dentate gyrus in mouse offspring. Reprod Toxicol. 2013;38:25-36 pubmed publisher
  • immunohistochemistry - free floating section; rat; 1:1000
Hung Y, Lai M, Tseng Y, Chou C, Lin Y. Monocyte chemoattractant protein-1 affects migration of hippocampal neural progenitors following status epilepticus in rats. J Neuroinflammation. 2013;10:11 pubmed publisher
  • immunocytochemistry; mouse
Pranski E, Dalal N, Sanford C, Herskowitz J, Gearing M, Lazo C, et al. RING finger protein 11 (RNF11) modulates susceptibility to 6-OHDA-induced nigral degeneration and behavioral deficits through NF-?B signaling in dopaminergic cells. Neurobiol Dis. 2013;54:264-79 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:300
Calu D, Kawa A, Marchant N, Navarre B, Henderson M, Chen B, et al. Optogenetic inhibition of dorsal medial prefrontal cortex attenuates stress-induced reinstatement of palatable food seeking in female rats. J Neurosci. 2013;33:214-26 pubmed publisher
  • immunohistochemistry - paraffin section; rat; 1:500
Cao L, Li L, Lin D, Zuo Z. Isoflurane induces learning impairment that is mediated by interleukin 1? in rodents. PLoS ONE. 2012;7:e51431 pubmed publisher
  • immunocytochemistry; rhesus macaque; 1:500
Putkhao K, Kocerha J, Cho I, Yang J, Parnpai R, Chan A. Pathogenic cellular phenotypes are germline transmissible in a transgenic primate model of Huntington's disease. Stem Cells Dev. 2013;22:1198-205 pubmed publisher
  • immunocytochemistry; human; 1:800
  • immunohistochemistry; human; 1:800
Trabalza A, Georgiadis C, Eleftheriadou I, Hislop J, Ellison S, Karavassilis M, et al. Venezuelan equine encephalitis virus glycoprotein pseudotyping confers neurotropism to lentiviral vectors. Gene Ther. 2013;20:723-32 pubmed publisher
  • immunohistochemistry - paraffin section; rat; 1:800
Zhu X, Huang C, Li Q, Guo Q, Wang Y, He X, et al. Temporal distribution of p300/CBP immunoreactivity in the adult rat spinal dorsal horn following chronic constriction injury (CCI). Cell Mol Neurobiol. 2013;33:197-204 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:5000
Ziebell J, Taylor S, Cao T, Harrison J, Lifshitz J. Rod microglia: elongation, alignment, and coupling to form trains across the somatosensory cortex after experimental diffuse brain injury. J Neuroinflammation. 2012;9:247 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:2000
Piskuric N, Vollmer C, Nurse C. Confocal immunofluorescence study of rat aortic body chemoreceptors and associated neurons in situ and in vitro. J Comp Neurol. 2011;519:856-73 pubmed publisher
  • immunocytochemistry; human
  • western blot; human
Burré J, Sharma M, Tsetsenis T, Buchman V, Etherton M, Südhof T. Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro. Science. 2010;329:1663-7 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:1000
Kawano J, Tanizawa Y, Shinoda K. Wolfram syndrome 1 (Wfs1) gene expression in the normal mouse visual system. J Comp Neurol. 2008;510:1-23 pubmed publisher
  • immunohistochemistry; mouse
Zaheer A, Zaheer S, Thangavel R, Wu Y, Sahu S, Yang B. Glia maturation factor modulates beta-amyloid-induced glial activation, inflammatory cytokine/chemokine production and neuronal damage. Brain Res. 2008;1208:192-203 pubmed publisher
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Plachez C, Lindwall C, Sunn N, Piper M, Moldrich R, Campbell C, et al. Nuclear factor I gene expression in the developing forebrain. J Comp Neurol. 2008;508:385-401 pubmed publisher
  • immunohistochemistry; chicken; 1:400
Brunet N, Tarabal O, Portero Otín M, Oppenheim R, Esquerda J, Caldero J. Survival and death of mature avian motoneurons in organotypic slice culture: trophic requirements for survival and different types of degeneration. J Comp Neurol. 2007;501:669-90 pubmed
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Papay R, Gaivin R, Jha A, McCune D, McGrath J, Rodrigo M, et al. Localization of the mouse alpha1A-adrenergic receptor (AR) in the brain: alpha1AAR is expressed in neurons, GABAergic interneurons, and NG2 oligodendrocyte progenitors. J Comp Neurol. 2006;497:209-22 pubmed
Pang D, Yang C, Luo Q, Li C, Liu W, Li L, et al. Soy isoflavones improve the oxidative stress induced hypothalamic inflammation and apoptosis in high fat diet-induced obese male mice through PGC1-alpha pathway. Aging (Albany NY). 2020;12:8710-8727 pubmed publisher
Gӧbel J, Engelhardt E, Pelzer P, Sakthivelu V, Jahn H, Jevtic M, et al. Mitochondria-Endoplasmic Reticulum Contacts in Reactive Astrocytes Promote Vascular Remodeling. Cell Metab. 2020;31:791-808.e8 pubmed publisher
Rohn F, Kordes C, Buschmann T, Reichert D, Wammers M, Poschmann G, et al. Impaired integrin α5 /β1 -mediated hepatocyte growth factor release by stellate cells of the aged liver. Aging Cell. 2020;19:e13131 pubmed publisher
Chao C, Gutiérrez Vázquez C, Rothhammer V, Mayo L, Wheeler M, Tjon E, et al. Metabolic Control of Astrocyte Pathogenic Activity via cPLA2-MAVS. Cell. 2019;179:1483-1498.e22 pubmed publisher
Wu J, Ardah M, Haikal C, Svanbergsson A, Diepenbroek M, Vaikath N, et al. Dihydromyricetin and Salvianolic acid B inhibit alpha-synuclein aggregation and enhance chaperone-mediated autophagy. Transl Neurodegener. 2019;8:18 pubmed publisher
He Q, Gao Y, Wang T, Zhou L, Zhou W, Yuan Z. Deficiency of Yes-Associated Protein Induces Cataract in Mice. Aging Dis. 2019;10:293-306 pubmed publisher
Bouyakdan K, Martin H, Liénard F, Budry L, Taïb B, Rodaros D, et al. The gliotransmitter ACBP controls feeding and energy homeostasis via the melanocortin system. J Clin Invest. 2019;129:2417-2430 pubmed publisher
Liang Y, Chen C, Xia B, Wu W, Tang J, Chen Q, et al. Neuroprotective Effect of Echinacoside in Subacute Mouse Model of Parkinson's Disease. Biomed Res Int. 2019;2019:4379639 pubmed publisher
Khuu M, Pagan C, Nallamothu T, Hevner R, Hodge R, Ramirez J, et al. Intermittent Hypoxia Disrupts Adult Neurogenesis and Synaptic Plasticity in the Dentate Gyrus. J Neurosci. 2019;39:1320-1331 pubmed publisher
Piroli G, Manuel A, Patel T, Walla M, Shi L, Lanci S, et al. Identification of Novel Protein Targets of Dimethyl Fumarate Modification in Neurons and Astrocytes Reveals Actions Independent of Nrf2 Stabilization. Mol Cell Proteomics. 2019;18:504-519 pubmed publisher
Yin W, Satkunendran T, Mo R, Morrissy S, Zhang X, Huang E, et al. Dual Regulatory Functions of SUFU and Targetome of GLI2 in SHH Subgroup Medulloblastoma. Dev Cell. 2019;48:167-183.e5 pubmed publisher
Goulao M, Ghosh B, Urban M, Sahu M, Mercogliano C, Charsar B, et al. Astrocyte progenitor transplantation promotes regeneration of bulbospinal respiratory axons, recovery of diaphragm function, and a reduced macrophage response following cervical spinal cord injury. Glia. 2019;67:452-466 pubmed publisher
Botella Lopez A, Garcia Lopez R, Pombero A, Martinez S. Radial glia fibers translate Fgf8 morphogenetic signals to generate a thalamic nuclear complex protomap in the mantle layer. Brain Struct Funct. 2019;224:661-679 pubmed publisher
Yu W, Shi X, Cui X, Niu Y, Zhang W, Bai X, et al. Jian-Pi-Zhi-Dong-Decoction regulates the expression of glutamate transporters to attenuate glutamate excitotoxicity and exerts anti-tics effects in Tourette syndrome model rats. Neuropsychiatr Dis Treat. 2018;14:3381-3392 pubmed publisher
Weise S, Villarreal A, Heidrich S, Dehghanian F, Schachtrup C, Nestel S, et al. TGFβ-Signaling and FOXG1-Expression Are a Hallmark of Astrocyte Lineage Diversity in the Murine Ventral and Dorsal Forebrain. Front Cell Neurosci. 2018;12:448 pubmed publisher
Beldick S, Hong J, Altamentova S, Khazaei M, Hundal A, Zavvarian M, et al. Severe-combined immunodeficient rats can be used to generate a model of perinatal hypoxic-ischemic brain injury to facilitate studies of engrafted human neural stem cells. PLoS ONE. 2018;13:e0208105 pubmed publisher
Mayoral S, Etxeberria A, Shen Y, Chan J. Initiation of CNS Myelination in the Optic Nerve Is Dependent on Axon Caliber. Cell Rep. 2018;25:544-550.e3 pubmed publisher
Luo F, Tran A, Xin L, Sanapala C, Lang B, Silver J, et al. Modulation of proteoglycan receptor PTPσ enhances MMP-2 activity to promote recovery from multiple sclerosis. Nat Commun. 2018;9:4126 pubmed publisher
Cheng L, Chen L, Wei X, Wang Y, Ren Z, Zeng S, et al. NOD2 promotes dopaminergic degeneration regulated by NADPH oxidase 2 in 6-hydroxydopamine model of Parkinson's disease. J Neuroinflammation. 2018;15:243 pubmed publisher
Welliver R, Polanco J, Seidman R, Sinha A, O Bara M, Khaku Z, et al. Muscarinic Receptor M3R Signaling Prevents Efficient Remyelination by Human and Mouse Oligodendrocyte Progenitor Cells. J Neurosci. 2018;38:6921-6932 pubmed publisher
Rangaraju S, Dammer E, Raza S, Gao T, Xiao H, Betarbet R, et al. Quantitative proteomics of acutely-isolated mouse microglia identifies novel immune Alzheimer's disease-related proteins. Mol Neurodegener. 2018;13:34 pubmed publisher
Kelley M, Cardarelli R, Smalley J, Ollerhead T, Andrew P, Brandon N, et al. Locally Reducing KCC2 Activity in the Hippocampus is Sufficient to Induce Temporal Lobe Epilepsy. EBioMedicine. 2018;32:62-71 pubmed publisher
Luo F, Zhang J, Burke K, Romito Digiacomo R, Miller R, Yang Y. Oligodendrocyte-specific loss of Cdk5 disrupts the architecture of nodes of Ranvier as well as learning and memory. Exp Neurol. 2018;306:92-104 pubmed publisher
GALLOWAY A, Adeluyi A, O Donovan B, Fisher M, Rao C, Critchfield P, et al. Dopamine Triggers CTCF-Dependent Morphological and Genomic Remodeling of Astrocytes. J Neurosci. 2018;38:4846-4858 pubmed publisher
Mukhamedshina Y, Akhmetzyanova E, Kostennikov A, Zakirova E, Galieva L, Garanina E, et al. Adipose-Derived Mesenchymal Stem Cell Application Combined With Fibrin Matrix Promotes Structural and Functional Recovery Following Spinal Cord Injury in Rats. Front Pharmacol. 2018;9:343 pubmed publisher
Oldrini B, Curiel García A, Marques C, Matia V, Uluçkan O, Graña Castro O, et al. Somatic genome editing with the RCAS-TVA-CRISPR-Cas9 system for precision tumor modeling. Nat Commun. 2018;9:1466 pubmed publisher
Beckel J, Gómez N, Lu W, Campagno K, Nabet B, Albalawi F, et al. Stimulation of TLR3 triggers release of lysosomal ATP in astrocytes and epithelial cells that requires TRPML1 channels. Sci Rep. 2018;8:5726 pubmed publisher
Fröhlich D, Suchowerska A, Voss C, He R, Wolvetang E, von Jonquieres G, et al. Expression Pattern of the Aspartyl-tRNA Synthetase DARS in the Human Brain. Front Mol Neurosci. 2018;11:81 pubmed publisher
Gong Z, Zhou Q. Dnmt3a in the dorsal dentate gyrus is a key regulator of fear renewal. Sci Rep. 2018;8:5093 pubmed publisher
Kim H, Koo Y, Shin M, Kim S, Shin Y, Choi B, et al. Combination of Constraint-Induced Movement Therapy with Electroacupuncture Improves Functional Recovery following Neonatal Hypoxic-Ischemic Brain Injury in Rats. Biomed Res Int. 2018;2018:8638294 pubmed publisher
Wang R, Zhao X, Xu J, Wen Y, Li A, Lu M, et al. Astrocytic JWA deletion exacerbates dopaminergic neurodegeneration by decreasing glutamate transporters in mice. Cell Death Dis. 2018;9:352 pubmed publisher
Tatsumi K, Isonishi A, Yamasaki M, Kawabe Y, Morita Takemura S, Nakahara K, et al. Olig2-Lineage Astrocytes: A Distinct Subtype of Astrocytes That Differs from GFAP Astrocytes. Front Neuroanat. 2018;12:8 pubmed publisher
Piao Y, Gwon D, Kang D, Hwang T, Shin N, Kwon H, et al. TLR4-mediated autophagic impairment contributes to neuropathic pain in chronic constriction injury mice. Mol Brain. 2018;11:11 pubmed publisher
Tzeng T, Chen C, Chen C, Tsay H, Lee L, Chen W, et al. The Cyanthin Diterpenoid and Sesterterpene Constituents of Hericium erinaceus Mycelium Ameliorate Alzheimer's Disease-Related Pathologies in APP/PS1 Transgenic Mice. Int J Mol Sci. 2018;19: pubmed publisher
Oda S, Tsuneoka Y, Yoshida S, Adachi Akahane S, Ito M, Kuroda M, et al. Immunolocalization of muscarinic M1 receptor in the rat medial prefrontal cortex. J Comp Neurol. 2018;526:1329-1350 pubmed publisher
Wu D, Lee S, Luo J, Xia H, Gushchina S, Richardson P, et al. Intraneural Injection of ATP Stimulates Regeneration of Primary Sensory Axons in the Spinal Cord. J Neurosci. 2018;38:1351-1365 pubmed publisher
Janova H, Arinrad S, Balmuth E, Mitjans M, Hertel J, Habes M, et al. Microglia ablation alleviates myelin-associated catatonic signs in mice. J Clin Invest. 2018;128:734-745 pubmed publisher
Olde Engberink A, Hernandez R, de Graan P, Gruol D. Rapamycin-Sensitive Late-LTP is Enhanced in the Hippocampus of IL-6 Transgenic Mice. Neuroscience. 2017;367:200-210 pubmed publisher
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Li D, Liu C, Yang C, Wang D, Wu D, Qi Y, et al. Slow Intrathecal Injection of rAAVrh10 Enhances its Transduction of Spinal Cord and Therapeutic Efficacy in a Mutant SOD1 Model of ALS. Neuroscience. 2017;365:192-205 pubmed publisher
Basu R, Duan X, Taylor M, Martin E, Muralidhar S, Wang Y, et al. Heterophilic Type II Cadherins Are Required for High-Magnitude Synaptic Potentiation in the Hippocampus. Neuron. 2017;96:160-176.e8 pubmed publisher
Hong Y, Zhao T, Li X, Li S. Mutant Huntingtin Inhibits αB-Crystallin Expression and Impairs Exosome Secretion from Astrocytes. J Neurosci. 2017;37:9550-9563 pubmed publisher
Yang Y, Yang S, Guo J, Cui Y, Tang B, Li X, et al. Synergistic Toxicity of Polyglutamine-Expanded TATA-Binding Protein in Glia and Neuronal Cells: Therapeutic Implications for Spinocerebellar Ataxia 17. J Neurosci. 2017;37:9101-9115 pubmed publisher
Stein L, Zorumski C, Izumi Y. Hippocampal slice preparation in rats acutely suppresses immunoreactivity of microtubule-associated protein (Map2) and glycogen levels without affecting numbers of glia or levels of the glutamate transporter VGlut1. Brain Behav. 2017;7:e00736 pubmed publisher
Long Q, Upadhya D, Hattiangady B, Kim D, An S, Shuai B, et al. Intranasal MSC-derived A1-exosomes ease inflammation, and prevent abnormal neurogenesis and memory dysfunction after status epilepticus. Proc Natl Acad Sci U S A. 2017;114:E3536-E3545 pubmed publisher
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product information
Catalog Number :
MAB360
Subcategory :
Neuroscience
Product Name :
Anti-Glial Fibrillary Acidic Protein Antibody, clone GA5
Product Type :
Antibodies
Clonality :
Monoclonal Antibody
Gene ID :
P14136
Host Name :
Mouse
Antigen :
Glial Fibrillary Acidic Protein
Clone :
GA5
Conjugate :
Ascites
Isotype :
IgG1
Product Description :
Anti-Glial Fibrillary Acidic Protein Antibody, clone GA5
Cross Reactivity :
Bovine;Chicken;Human;Mouse;Pig;Rat;Rabbit
Background :
Glial fibrillary acidic protein is a class-III intermediate filament. GFAP is the main constituent of intermediate filaments in astrocytes and serves as a cell specific marker that distinguishes differentiated astrocytes from other glial cells during the development of the central nervous system.
ALT Names :
GFAP
Immunogen :
Purified GFAP from porcine spinal cord.
Specificity :
Glial fibrillar acidic protein. On western blots of extracts from a human glioma cell line (U33CG/343MG), MAB360 recognizes a band at approximately 51 kDa corresponding to GFAP (Debus, 1983). By immunohistochemistry it recognizes astrocytes and Bergmann glia cells, glioma and glial cell derived tumors. Shows no cross-reactivity with vimentin.
Package Size :
100 µL
Uses :
Immunocytochemistry;Immunohistochemistry;Immunohistochemistry (Paraffin);Western Blotting
Storage :
Stable for 1 year at -20ºC from date of receipt. Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
company information
EMD Millipore
290 Concord Road
Billerica, Massachusetts 01821
bioscienceshelp@emdchemical.com
https://www.emdmillipore.com
888-854-3417
headquarters: United States
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

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