This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
EMD Millipore
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
product type :
antibody
product name :
Substance P Antibody, pain, clone NC1
catalog :
MAB356
quantity :
100 μL
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
NC1
reactivity :
guinea pig, human, mouse, rat, pigs , domestic rabbit, rhesus macaque
application :
immunohistochemistry, immunohistochemistry - frozen section, immunohistochemistry - free floating section
citations: 41
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; 1:500; loading ...; fig 4d
Merchan Sala P, Nardini D, Waclaw R, Campbell K. Selective neuronal expression of the SoxE factor, Sox8, in direct pathway striatal projection neurons of the developing mouse brain. J Comp Neurol. 2017;525:2805-2819 pubmed publisher
  • immunohistochemistry - free floating section; mouse; 1:2000; loading ...; fig 13g
Quina L, Harris J, Zeng H, Turner E. Specific connections of the interpeduncular subnuclei reveal distinct components of the habenulopeduncular pathway. J Comp Neurol. 2017;525:2632-2656 pubmed publisher
  • immunohistochemistry; rat; 1:1000; fig s1
Zhang L, Hernandez V, Vázquez Juárez E, Chay F, Barrio R. Thirst Is Associated with Suppression of Habenula Output and Active Stress Coping: Is there a Role for a Non-canonical Vasopressin-Glutamate Pathway?. Front Neural Circuits. 2016;10:13 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:150
Stenkamp Strahm C, Nyavor Y, Kappmeyer A, Horton S, Gericke M, Balemba O. Prolonged high fat diet ingestion, obesity, and type 2 diabetes symptoms correlate with phenotypic plasticity in myenteric neurons and nerve damage in the mouse duodenum. Cell Tissue Res. 2015;361:411-26 pubmed publisher
  • immunohistochemistry; rat; 1:500
Li J, Wang X, Gao C, Liao Y, Qu J, He Z, et al. Neurochemical phenotype and function of endomorphin 2-immunopositive neurons in the myenteric plexus of the rat colon. Front Neuroanat. 2014;8:149 pubmed publisher
  • immunohistochemistry - free floating section; guinea pig; 1:200; fig 8
Yuan S, Vilimas P, Zagorodnyuk V, Gibbins I. Novel spinal pathways identified by neuronal c-Fos expression after urethrogenital reflex activation in female guinea pigs. Neuroscience. 2015;288:37-50 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:200
Yin J, Wu H, Dong Y, Zhang T, Wang J, Zhang Y, et al. Neurochemical properties of BDNF-containing neurons projecting to rostral ventromedial medulla in the ventrolateral periaqueductal gray. Front Neural Circuits. 2014;8:137 pubmed publisher
  • immunohistochemistry - frozen section; domestic rabbit; 1:200
Hsieh Y, Yang C, Liu S, Chou L, Hong C. Remote dose-dependent effects of dry needling at distant myofascial trigger spots of rabbit skeletal muscles on reduction of substance P levels of proximal muscle and spinal cords. Biomed Res Int. 2014;2014:982121 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:500
Gardon O, Faget L, Chu Sin Chung P, Matifas A, Massotte D, Kieffer B. Expression of mu opioid receptor in dorsal diencephalic conduction system: new insights for the medial habenula. Neuroscience. 2014;277:595-609 pubmed publisher
  • immunohistochemistry - free floating section; mouse; 1:125
Dolan J, Mitchell K. Mutation of Elfn1 in mice causes seizures and hyperactivity. PLoS ONE. 2013;8:e80491 pubmed publisher
  • immunohistochemistry; mouse; 1:200
Chen T, Wang X, Qu J, Wang W, Zhang T, Yanagawa Y, et al. Neurokinin-1 receptor-expressing neurons that contain serotonin and gamma-aminobutyric acid in the rat rostroventromedial medulla are involved in pain processing. J Pain. 2013;14:778-92 pubmed publisher
  • immunohistochemistry; pigs ; 1:500
Sharrad D, Gai W, Brookes S. Selective coexpression of synaptic proteins, ?-synuclein, cysteine string protein-?, synaptophysin, synaptotagmin-1, and synaptobrevin-2 in vesicular acetylcholine transporter-immunoreactive axons in the guinea pig ileum. J Comp Neurol. 2013;521:2523-37 pubmed publisher
  • immunohistochemistry; rhesus macaque; 1:200
Gonzales K, Pare J, Wichmann T, Smith Y. GABAergic inputs from direct and indirect striatal projection neurons onto cholinergic interneurons in the primate putamen. J Comp Neurol. 2013;521:2502-22 pubmed publisher
  • immunohistochemistry; pigs ; 1:500
Sharrad D, Chen B, Brookes S. Neurochemical coding compared between varicose axons and cell bodies of myenteric neurons in the guinea-pig ileum. Neurosci Lett. 2013;534:171-6 pubmed publisher
  • immunohistochemistry; guinea pig; 1:500
  • immunohistochemistry; human; 1:500
Sharrad D, de Vries E, Brookes S. Selective expression of ?-synuclein-immunoreactivity in vesicular acetylcholine transporter-immunoreactive axons in the guinea pig rectum and human colon. J Comp Neurol. 2013;521:657-76 pubmed publisher
  • immunohistochemistry - frozen section; human; 1:100
Díaz E, Bravo D, Rojas X, Concha M. Morphologic and immunohistochemical organization of the human habenular complex. J Comp Neurol. 2011;519:3727-47 pubmed publisher
  • immunohistochemistry - free floating section; rat; 1:500
Wolansky T, Pagliardini S, Greer J, Dickson C. Immunohistochemical characterization of substance P receptor (NK(1)R)-expressing interneurons in the entorhinal cortex. J Comp Neurol. 2007;502:427-41 pubmed
  • immunohistochemistry - free floating section; rat; 1:100
Rosin D, Chang D, Guyenet P. Afferent and efferent connections of the rat retrotrapezoid nucleus. J Comp Neurol. 2006;499:64-89 pubmed
  • immunohistochemistry; pigs ; 1:200
Liu S, Gao N, Hu H, Wang X, Wang G, Fang X, et al. Distribution and chemical coding of corticotropin-releasing factor-immunoreactive neurons in the guinea pig enteric nervous system. J Comp Neurol. 2006;494:63-74 pubmed
  • immunohistochemistry; guinea pig; 1:200
Hu H, Gao N, Liu S, Ren J, Wang X, Xia Y, et al. Action of bradykinin in the submucosal plexus of guinea pig small intestine. J Pharmacol Exp Ther. 2004;309:320-7 pubmed
Oliver R, Purohit D, Kharidia K, Mandyam C. Transient Chemogenetic Inhibition of D1-MSNs in the Dorsal Striatum Enhances Methamphetamine Self-Administration. Brain Sci. 2019;9: pubmed publisher
Miyamoto Y, Nagayoshi I, Nishi A, Fukuda T. Three divisions of the mouse caudal striatum differ in the proportions of dopamine D1 and D2 receptor-expressing cells, distribution of dopaminergic axons, and composition of cholinergic and GABAergic interneurons. Brain Struct Funct. 2019;224:2703-2716 pubmed publisher
Tatematsu Y, Khan Q, Blanco T, Bair J, Hodges R, Masli S, et al. Thrombospondin-1 Is Necessary for the Development and Repair of Corneal Nerves. Int J Mol Sci. 2018;19: pubmed publisher
Miyamoto Y, Katayama S, Shigematsu N, Nishi A, Fukuda T. Striosome-based map of the mouse striatum that is conformable to both cortical afferent topography and uneven distributions of dopamine D1 and D2 receptor-expressing cells. Brain Struct Funct. 2018;223:4275-4291 pubmed publisher
Zhong W, Chebolu S, Darmani N. Intracellular emetic signaling evoked by the L-type Ca2+ channel agonist FPL64176 in the least shrew (Cryptotis parva). Eur J Pharmacol. 2018;834:157-168 pubmed publisher
Stenkamp Strahm C, Kappmeyer A, Schmalz J, Gericke M, Balemba O. High-fat diet ingestion correlates with neuropathy in the duodenum myenteric plexus of obese mice with symptoms of type 2 diabetes. Cell Tissue Res. 2013;354:381-94 pubmed publisher
Aizawa H, Kobayashi M, Tanaka S, Fukai T, Okamoto H. Molecular characterization of the subnuclei in rat habenula. J Comp Neurol. 2012;520:4051-66 pubmed publisher
Kurahashi M, Nakano Y, Hennig G, Ward S, Sanders K. Platelet-derived growth factor receptor ?-positive cells in the tunica muscularis of human colon. J Cell Mol Med. 2012;16:1397-404 pubmed publisher
Ramalingam S, Daughtridge G, Johnston M, Gracz A, Magness S. Distinct levels of Sox9 expression mark colon epithelial stem cells that form colonoids in culture. Am J Physiol Gastrointest Liver Physiol. 2012;302:G10-20 pubmed publisher
Hu H, Rusbridge C, Constantino Casas F, Jeffery N. Distribution of substance P and calcitonin gene-related peptide in the spinal cord of Cavalier King Charles Spaniels affected by symptomatic syringomyelia. Res Vet Sci. 2012;93:318-20 pubmed publisher
Yuan S, Gibbins I, Zagorodnyuk V, Morris J. Sacro-lumbar intersegmental spinal reflex in autonomic pathways mediating female sexual function. J Sex Med. 2011;8:1931-42 pubmed publisher
Ding S, Chi M, Scull B, Rigby R, Schwerbrock N, MAGNESS S, et al. High-fat diet: bacteria interactions promote intestinal inflammation which precedes and correlates with obesity and insulin resistance in mouse. PLoS ONE. 2010;5:e12191 pubmed publisher
Gracz A, Ramalingam S, Magness S. Sox9 expression marks a subset of CD24-expressing small intestine epithelial stem cells that form organoids in vitro. Am J Physiol Gastrointest Liver Physiol. 2010;298:G590-600 pubmed publisher
Ray A, Chebolu S, Darmani N. Receptor-selective agonists induce emesis and Fos expression in the brain and enteric nervous system of the least shrew (Cryptotis parva). Pharmacol Biochem Behav. 2009;94:211-8 pubmed publisher
Niu L, Chen T, Wang Y, Li Y. Neurochemical phenotypes of endomorphin-2-containing neurons in vagal nodose neurons of the adult rat. Neurochem Int. 2009;55:542-51 pubmed publisher
Formeister E, Sionas A, Lorance D, Barkley C, Lee G, Magness S. Distinct SOX9 levels differentially mark stem/progenitor populations and enteroendocrine cells of the small intestine epithelium. Am J Physiol Gastrointest Liver Physiol. 2009;296:G1108-18 pubmed publisher
Dellarole A, Grilli M. Adult dorsal root ganglia sensory neurons express the early neuronal fate marker doublecortin. J Comp Neurol. 2008;511:318-28 pubmed publisher
Sekizawa S, Chen C, Bechtold A, Tabor J, Bric J, Pinkerton K, et al. Extended secondhand tobacco smoke exposure induces plasticity in nucleus tractus solitarius second-order lung afferent neurons in young guinea pigs. Eur J Neurosci. 2008;28:771-81 pubmed publisher
Schneider D, Yan H, Fry L, Alverson J, White S, O Rourke K. Myenteric neurons of the ileum that express somatostatin are a target of prion neuroinvasion in an alimentary model of sheep scrapie. Acta Neuropathol. 2008;115:651-61 pubmed publisher
Mulkey D, Rosin D, West G, Takakura A, Moreira T, Bayliss D, et al. Serotonergic neurons activate chemosensitive retrotrapezoid nucleus neurons by a pH-independent mechanism. J Neurosci. 2007;27:14128-38 pubmed
Liu S, Gao X, Gao N, Wang X, Fang X, Hu H, et al. Expression of type 1 corticotropin-releasing factor receptor in the guinea pig enteric nervous system. J Comp Neurol. 2005;481:284-98 pubmed
product information
Catalog Number :
MAB356
Subcategory :
Neuroscience
Product Name :
Anti-Substance P Antibody, pain, clone NC1
Product Type :
Antibodies
Clonality :
Monoclonal Antibody
Gene ID :
P20366
Host Name :
Rat
Antigen :
Substance P
Clone :
NC1
Conjugate :
Culture Supernatant
Isotype :
IgG2a
Product Description :
Anti-Substance P Antibody, pain, clone NC1
Cross Reactivity :
Human;Mammals
Immunogen :
Substance P conjugated to BSA.
Specificity :
Reacts with COOH-terminal end of Substance P. No cross-reactivity to Leu- or Met- enkephalin, somatostatin or beta-endorphin. Eledoisin 5%.
Package Size :
100 μL
Uses :
Immunohistochemistry
Storage :
Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
company information
EMD Millipore
290 Concord Road
Billerica, Massachusetts 01821
bioscienceshelp@emdchemical.com
https://www.emdmillipore.com
888-854-3417
headquarters: United States
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

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