Serotonin Antibody, clone YC5/45 | EMD Millipore MAB352 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Serotonin Antibody, clone YC5/45

catalog :

MAB352

quantity :

100 μL

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

YC5/45

reactivity :

mouse, rat, pigs , Xenopus laevis

application :

immunohistochemistry, immunohistochemistry - frozen section, immunohistochemistry - free floating section

citations: 37

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - frozen section; mouse; fig 4a	Dias D, Kim H, Holl D, Werne Solnestam B, Lundeberg J, Carlen M, et al. Reducing Pericyte-Derived Scarring Promotes Recovery after Spinal Cord Injury. Cell. 2018;173:153-165.e22 pubmed publisher
immunohistochemistry; Xenopus laevis; 1:100; loading ...; fig 2a	Xavier A, Fontaine R, Bloch S, Affaticati P, Jenett A, Demarque M, et al. Comparative analysis of monoaminergic cerebrospinal fluid-contacting cells in Osteichthyes (bony vertebrates). J Comp Neurol. 2017;525:2265-2283 pubmed publisher
immunohistochemistry; mouse; 1:500; loading ...; tbl 1	Sos K, Mayer M, Cserép C, Takács F, Szonyi A, Freund T, et al. Cellular architecture and transmitter phenotypes of neurons of the mouse median raphe region. Brain Struct Funct. 2017;222:287-299 pubmed publisher
immunohistochemistry; mouse; 1:100; fig 2	Ahn M, Kalume F, Pitstick R, Oehler A, Carlson G, Dearmond S. Brain Aggregates: An Effective In Vitro Cell Culture System Modeling Neurodegenerative Diseases. J Neuropathol Exp Neurol. 2016;75:256-62 pubmed publisher
immunohistochemistry; mouse; 1:500	SzÅ‘nyi A, Mayer M, CserÃ©p C, TakÃ¡cs V, Watanabe M, Freund T, et al. The ascending median raphe projections are mainly glutamatergic in the mouse forebrain. Brain Struct Funct. 2016;221:735-51 pubmed publisher
immunohistochemistry; mouse; 1:200	Chen T, Wang X, Qu J, Wang W, Zhang T, Yanagawa Y, et al. Neurokinin-1 receptor-expressing neurons that contain serotonin and gamma-aminobutyric acid in the rat rostroventromedial medulla are involved in pain processing. J Pain. 2013;14:778-92 pubmed publisher
immunohistochemistry; rat	Xu C, Giuliano F, Sun X, Brisorgueil M, Leclerc P, Vergé D, et al. Serotonin 5-HT2A and 5-HT5A receptors are expressed by different motoneuron populations in rat Onuf's nucleus. J Comp Neurol. 2007;502:620-34 pubmed
immunohistochemistry - free floating section; rat; 1:100	Rosin D, Chang D, Guyenet P. Afferent and efferent connections of the rat retrotrapezoid nucleus. J Comp Neurol. 2006;499:64-89 pubmed
immunohistochemistry; pigs ; 1:200	Liu S, Gao N, Hu H, Wang X, Wang G, Fang X, et al. Distribution and chemical coding of corticotropin-releasing factor-immunoreactive neurons in the guinea pig enteric nervous system. J Comp Neurol. 2006;494:63-74 pubmed
	Kaufman A, Choo E, Koh A, Dando R. Inflammation arising from obesity reduces taste bud abundance and inhibits renewal. PLoS Biol. 2018;16:e2001959 pubmed publisher
	Perrier J, Rasmussen H, Jørgensen L, Berg R. Intense Activity of the Raphe Spinal Pathway Depresses Motor Activity via a Serotonin Dependent Mechanism. Front Neural Circuits. 2017;11:111 pubmed publisher
	Alam T, Maruyama H, Li C, Pastuhov S, Nix P, Bastiani M, et al. Axotomy-induced HIF-serotonin signalling axis promotes axon regeneration in C. elegans. Nat Commun. 2016;7:10388 pubmed publisher
	Jaber L, Zhao F, Kolli T, Herness S. A physiologic role for serotonergic transmission in adult rat taste buds. PLoS ONE. 2014;9:e112152 pubmed publisher
	Toth S, Jonecová Z, Varga J, Stasko P, Kovalčinová B, Maretta M, et al. Immunohistochemical study of jejunal graft mucosa cell populations during the initial adaptation phase in the host body in rats. Acta Histochem. 2013;115:803-9 pubmed publisher
	Sundvik M, Chen Y, Panula P. Presenilin1 regulates histamine neuron development and behavior in zebrafish, danio rerio. J Neurosci. 2013;33:1589-97 pubmed publisher
	Yokogawa T, Hannan M, Burgess H. The dorsal raphe modulates sensory responsiveness during arousal in zebrafish. J Neurosci. 2012;32:15205-15 pubmed publisher
	Fu Y, Peng S, Lin H, Pasricha P, Tang S. 3-D imaging and illustration of mouse intestinal neurovascular complex. Am J Physiol Gastrointest Liver Physiol. 2013;304:G1-11 pubmed publisher
	Razy Krajka F, Brown E, Horie T, Callebert J, Sasakura Y, Joly J, et al. Monoaminergic modulation of photoreception in ascidian: evidence for a proto-hypothalamo-retinal territory. BMC Biol. 2012;10:45 pubmed publisher
	Sundvik M, Panula P. Organization of the histaminergic system in adult zebrafish (Danio rerio) brain: neuron number, location, and cotransmitters. J Comp Neurol. 2012;520:3827-45 pubmed publisher
	Eaton J, Roache L, Nguyen K, Cushing B, Troyer E, Papademetriou E, et al. Organizational effects of oxytocin on serotonin innervation. Dev Psychobiol. 2012;54:92-7 pubmed publisher
	Serre A, Snyder E, Mallet J, Buchet D. Overexpression of basic helix-loop-helix transcription factors enhances neuronal differentiation of fetal human neural progenitor cells in various ways. Stem Cells Dev. 2012;21:539-53 pubmed publisher
	Penkova N, Baltadjiev G, Koeva Y, Atanassova P, Andonov V, Trichkova V. Serotonin-producing cells in human gastric mucosa--immunohistochemical and electron microscopic study. Folia Med (Plovdiv). 2010;52:31-7 pubmed
	Kumar A, Nevill G, Brockes J, Forge A. A comparative study of gland cells implicated in the nerve dependence of salamander limb regeneration. J Anat. 2010;217:16-25 pubmed publisher
	Noga B, Johnson D, Riesgo M, Pinzon A. Locomotor-activated neurons of the cat. I. Serotonergic innervation and co-localization of 5-HT7, 5-HT2A, and 5-HT1A receptors in the thoraco-lumbar spinal cord. J Neurophysiol. 2009;102:1560-76 pubmed publisher
	Donohoe D, Jarvis R, Weeks K, Aamodt E, Dwyer D. Behavioral adaptation in C. elegans produced by antipsychotic drugs requires serotonin and is associated with calcium signaling and calcineurin inhibition. Neurosci Res. 2009;64:280-9 pubmed publisher
	Le Verche V, Kaindl A, Verney C, Csaba Z, Peineau S, Olivier P, et al. The somatostatin 2A receptor is enriched in migrating neurons during rat and human brain development and stimulates migration and axonal outgrowth. PLoS ONE. 2009;4:e5509 pubmed publisher
	Rotte C, Witte J, Blenau W, Baumann O, Walz B. Source, topography and excitatory effects of GABAergic innervation in cockroach salivary glands. J Exp Biol. 2009;212:126-36 pubmed publisher
	Lillesaar C, Stigloher C, Tannhäuser B, Wullimann M, Bally Cuif L. Axonal projections originating from raphe serotonergic neurons in the developing and adult zebrafish, Danio rerio, using transgenics to visualize raphe-specific pet1 expression. J Comp Neurol. 2009;512:158-82 pubmed publisher
	Huo F, Chen T, Lv B, Wang J, Zhang T, Qu C, et al. Synaptic connections between GABAergic elements and serotonergic terminals or projecting neurons in the ventrolateral orbital cortex. Cereb Cortex. 2009;19:1263-72 pubmed publisher
	Ubeda Banon I, Novejarque A, Mohedano Moriano A, Pro Sistiaga P, Insausti R, Martinez Garcia F, et al. Vomeronasal inputs to the rodent ventral striatum. Brain Res Bull. 2008;75:467-73 pubmed publisher
	Mulkey D, Rosin D, West G, Takakura A, Moreira T, Bayliss D, et al. Serotonergic neurons activate chemosensitive retrotrapezoid nucleus neurons by a pH-independent mechanism. J Neurosci. 2007;27:14128-38 pubmed
	Casanovas A, Hernandez S, Tarabal O, Rosselló J, Esquerda J. Strong P2X4 purinergic receptor-like immunoreactivity is selectively associated with degenerating neurons in transgenic rodent models of amyotrophic lateral sclerosis. J Comp Neurol. 2008;506:75-92 pubmed
	Tomchik S, Berg S, Kim J, Chaudhari N, Roper S. Breadth of tuning and taste coding in mammalian taste buds. J Neurosci. 2007;27:10840-8 pubmed
	Tyler M, Cameron D. Cellular pattern formation during retinal regeneration: a role for homotypic control of cell fate acquisition. Vision Res. 2007;47:501-11 pubmed
	Lee H, Park S, Song W, Waterhouse B. Retrograde study of hypocretin-1 (orexin-A) projections to subdivisions of the dorsal raphe nucleus in the rat. Brain Res. 2005;1059:35-45 pubmed
	Tyler M, Carney L, Cameron D. Control of cellular pattern formation in the vertebrate inner retina by homotypic regulation of cell-fate decisions. J Neurosci. 2005;25:4565-76 pubmed
	Lee H, Lee B, Waterhouse B. Retrograde study of projections from the tuberomammillary nucleus to the dorsal raphe and the locus coeruleus in the rat. Brain Res. 2005;1043:65-75 pubmed

product information

Catalog Number :

MAB352

Subcategory :

Neuroscience

Product Name :

Anti-Serotonin Antibody, clone YC5/45

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Host Name :

Rat

Antigen :

Serotonin

Clone :

YC5/45

Conjugate :

Culture Supernatant

Isotype :

IgG

Product Description :

Anti-Serotonin Antibody, clone YC5/45

Cross Reactivity :

Human;Pig;Rat;Rabbit;Lizard;Mouse

ALT Names :

5-HT

Immunogen :

Serotonin conjugated to BSA.

Specificity :

Recognizes the formaldehyde conjugate of serotonin. Without paraformaldehyde treatment, it cross-reacts in liquid phase with dopamine and tryptamine in hemagglutination tests. Shows no reactivity with catecholamine-containing neurons in formaldehyde fixed preparations. MAB352 reacts with serotonin in neurons and recognizes serotonergic sites in fixed tissue sections. By cell agglutination, no cross reactivity with 5-hydroxyindolacetic acid, GABA, noradrenaline, 5-hydroxytryptophan, carnosine or melatonin.

Package Size :

100 μL

Uses :

Immunohistochemistry

Storage :

Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.