MAP2 Antibody, Alexa Fluor® 488 conjugated | EMD Millipore MAB3418X product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

MAP2 Antibody, Alexa Fluor® 488 conjugated

catalog :

MAB3418X

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

AF488

clone name :

AP20

The same clone is also sold as:

Novus Biologicals: NB600-1372
Abcam: ab24279, ab63518
Invitrogen: MA5-12823, MA1-25044
OriGene: BM2472, BM2472F, BM2472B
LifeSpan Biosciences: LS-C87980
Santa Cruz Biotechnology: sc-32791
MilliporeSigma: M2320, M1406

reactivity :

human, mouse

application :

immunohistochemistry, immunocytochemistry

citations: 70

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; mouse	Cunningham M, Wirth J, Freeman L, Boger H, Granholm A, Gilkeson G. Estrogen receptor alpha deficiency protects against development of cognitive impairment in murine lupus. J Neuroinflammation. 2014;11:171 pubmed publisher
	Grande V, Manassero G, Vercelli A. Neuroprotective and anti-inflammatory roles of the phosphatase and tensin homolog deleted on chromosome Ten (PTEN) Inhibition in a Mouse Model of Temporal Lobe Epilepsy. PLoS ONE. 2014;9:e114554 pubmed publisher
	Carlessi L, Fusar Poli E, Bechi G, Mantegazza M, Pascucci B, Narciso L, et al. Functional and molecular defects of hiPSC-derived neurons from patients with ATM deficiency. Cell Death Dis. 2014;5:e1342 pubmed publisher
	Coimbra J, Collin S, Hart N. Topographic specializations in the retinal ganglion cell layer of Australian passerines. J Comp Neurol. 2014;522:3609-28 pubmed publisher
	Griffin S, Brinkman N, Hedrick E, Rhodes E, Fout G. Comparison of nucleic acid extraction and reverse transcription-qPCR approaches for detection of GI and GII noroviruses in drinking water. J Virol Methods. 2014;199:76-85 pubmed publisher
	Leusch F, Khan S, Gagnon M, Quayle P, Trinh T, Coleman H, et al. Assessment of wastewater and recycled water quality: a comparison of lines of evidence from in vitro, in vivo and chemical analyses. Water Res. 2014;50:420-31 pubmed publisher
	Novaes J, Carvalho E. Reproduction, food dynamics and exploitation level of Oreochromis niloticus (Perciformes: Cichlidae) from artisanal fisheries in Barra Bonita Reservoir, Brazil. Rev Biol Trop. 2012;60:721-34 pubmed
	Masclaux F, Hotz P, Friedli D, Savova Bianchi D, Oppliger A. High occurrence of hepatitis E virus in samples from wastewater treatment plants in Switzerland and comparison with other enteric viruses. Water Res. 2013;47:5101-9 pubmed publisher
	Turaç G, Hindley C, Thomas R, Davis J, Deleidi M, Gasser T, et al. Combined flow cytometric analysis of surface and intracellular antigens reveals surface molecule markers of human neuropoiesis. PLoS ONE. 2013;8:e68519 pubmed publisher
	Li L, Ginet V, Liu X, Vergun O, Tuittila M, Mathieu M, et al. The nNOS-p38MAPK pathway is mediated by NOS1AP during neuronal death. J Neurosci. 2013;33:8185-201 pubmed publisher
	Arsenault J, Ferrari E, Niranjan D, Cuijpers S, Gu C, Vallis Y, et al. Stapling of the botulinum type A protease to growth factors and neuropeptides allows selective targeting of neuroendocrine cells. J Neurochem. 2013;126:223-33 pubmed publisher
	Xu J, Nonogaki M, Madhira R, Ma H, Hermanson O, Kioussi C, et al. Population-specific regulation of Chmp2b by Lbx1 during onset of synaptogenesis in lateral association interneurons. PLoS ONE. 2012;7:e48573 pubmed publisher
	De Keuckelaere A, Baert L, Duarte A, Stals A, Uyttendaele M. Evaluation of viral concentration methods from irrigation and processing water. J Virol Methods. 2013;187:294-303 pubmed publisher
	Furutani Y, Kawasaki M, Matsuno H, Mitsui S, Mori K, Yoshihara Y. Vitronectin induces phosphorylation of ezrin/radixin/moesin actin-binding proteins through binding to its novel neuronal receptor telencephalin. J Biol Chem. 2012;287:39041-9 pubmed publisher
	Karnas D, Mordel J, Bonnet D, Pevet P, Hicks D, Meissl H. Heterogeneity of intrinsically photosensitive retinal ganglion cells in the mouse revealed by molecular phenotyping. J Comp Neurol. 2013;521:912-32 pubmed publisher
	Cai W, Carlson S, Brelsfoard J, Mannon C, Moncman C, Saatman K, et al. Rit GTPase signaling promotes immature hippocampal neuronal survival. J Neurosci. 2012;32:9887-97 pubmed publisher
	Seidl A, Sanchez J, Schecterson L, Tabor K, Wang Y, Kashima D, et al. Transgenic quail as a model for research in the avian nervous system: a comparative study of the auditory brainstem. J Comp Neurol. 2013;521:5-23 pubmed publisher
	Oukarroum A, Perreault F, Popovic R. Interactive effects of temperature and copper on photosystem II photochemistry in Chlorella vulgaris. J Photochem Photobiol B. 2012;110:9-14 pubmed publisher
	Corrêa A, Rigotto C, Moresco V, Kleemann C, Teixeira A, Poli C, et al. The depuration dynamics of oysters (Crassostrea gigas) artificially contaminated with hepatitis A virus and human adenovirus. Mem Inst Oswaldo Cruz. 2012;107:11-7 pubmed
	Abramowski D, Rabe S, Upadhaya A, Reichwald J, Danner S, Staab D, et al. Transgenic expression of intraneuronal A?42 but not A?40 leads to cellular A? lesions, degeneration, and functional impairment without typical Alzheimer's disease pathology. J Neurosci. 2012;32:1273-83 pubmed publisher
	Killian R, Flippin J, Herrera C, Almenar Queralt A, Goldstein L. Kinesin light chain 1 suppression impairs human embryonic stem cell neural differentiation and amyloid precursor protein metabolism. PLoS ONE. 2012;7:e29755 pubmed publisher
	Oukarroum A, Polchtchikov S, Perreault F, Popovic R. Temperature influence on silver nanoparticles inhibitory effect on photosystem II photochemistry in two green algae, Chlorella vulgaris and Dunaliella tertiolecta. Environ Sci Pollut Res Int. 2012;19:1755-62 pubmed publisher
	Kroehne V, Freudenreich D, Hans S, Kaslin J, Brand M. Regeneration of the adult zebrafish brain from neurogenic radial glia-type progenitors. Development. 2011;138:4831-41 pubmed publisher
	Borgesius N, de Waard M, van der Pluijm I, Omrani A, Zondag G, van der Horst G, et al. Accelerated age-related cognitive decline and neurodegeneration, caused by deficient DNA repair. J Neurosci. 2011;31:12543-53 pubmed publisher
	Rhodes E, Hamilton D, See M, Wymer L. Evaluation of hollow-fiber ultrafiltration primary concentration of pathogens and secondary concentration of viruses from water. J Virol Methods. 2011;176:38-45 pubmed publisher
	Tucker A, Driskell L, Pannell L, Wood D. Differential proteomic analysis of Rickettsia prowazekii propagated in diverse host backgrounds. Appl Environ Microbiol. 2011;77:4712-8 pubmed publisher
	Novaes J, Carvalho E. Population structure and stock assessment of Hoplias malabaricus (Characiformes: Erythrinidae) caught by artisanal fishermen in river-reservoir transition area in Brazil. Rev Biol Trop. 2011;59:71-83 pubmed
	Odraska P, Dolezalova L, Piler P, Oravec M, Blaha L. Utilization of the solid sorbent media in monitoring of airborne cyclophosphamide concentrations and the implications for occupational hygiene. J Environ Monit. 2011;13:1480-7 pubmed publisher
	Aroeira R, Ribeiro J, Sebastião A, Valente C. Age-related changes of glycine receptor at the rat hippocampus: from the embryo to the adult. J Neurochem. 2011;118:339-53 pubmed publisher
	Perreault F, Dionne J, Didur O, Juneau P, Popovic R. Effect of cadmium on photosystem II activity in Chlamydomonas reinhardtii: alteration of O-J-I-P fluorescence transients indicating the change of apparent activation energies within photosystem II. Photosynth Res. 2011;107:151-7 pubmed publisher
	Alvarez Flores M, Furlin D, Ramos O, Balan A, Konno K, Chudzinski Tavassi A. Losac, the first hemolin that exhibits procogulant activity through selective factor X proteolytic activation. J Biol Chem. 2011;286:6918-28 pubmed publisher
	Tabor K, Wong R, Rubel E. Topography and morphology of the inhibitory projection from superior olivary nucleus to nucleus laminaris in chickens (Gallus gallus). J Comp Neurol. 2011;519:358-75 pubmed publisher
	Chaitanya G, Eeka P, Munker R, Alexander J, Babu P. Role of cytotoxic protease granzyme-b in neuronal degeneration during human stroke. Brain Pathol. 2011;21:16-30 pubmed publisher
	Perreault F, Dewez D, Fortin C, Juneau P, Diallo A, Popovic R. Effect of aluminum on cellular division and photosynthetic electron transport in Euglena gracilis and Chlamydomonas acidophila. Environ Toxicol Chem. 2010;29:887-92 pubmed publisher
	Terauchi A, Peers G, Kobayashi M, Niyogi K, Merchant S. Trophic status of Chlamydomonas reinhardtii influences the impact of iron deficiency on photosynthesis. Photosynth Res. 2010;105:39-49 pubmed publisher
	Spigolon G, Veronesi C, Bonny C, Vercelli A. c-Jun N-terminal kinase signaling pathway in excitotoxic cell death following kainic acid-induced status epilepticus. Eur J Neurosci. 2010;31:1261-72 pubmed publisher
	Petit A, Eullaffroy P, Debenest T, Gagné F. Toxicity of PAMAM dendrimers to Chlamydomonas reinhardtii. Aquat Toxicol. 2010;100:187-93 pubmed publisher
	Dosnon Olette R, Trotel Aziz P, Couderchet M, Eullaffroy P. Fungicides and herbicide removal in Scenedesmus cell suspensions. Chemosphere. 2010;79:117-23 pubmed publisher
	Jiang Z, Belforte J, Lu Y, Yabe Y, Pickel J, Smith C, et al. eIF2alpha Phosphorylation-dependent translation in CA1 pyramidal cells impairs hippocampal memory consolidation without affecting general translation. J Neurosci. 2010;30:2582-94 pubmed publisher
	Sangoi A, McKenney J. A tissue microarray-based comparative analysis of novel and traditional immunohistochemical markers in the distinction between adrenal cortical lesions and pheochromocytoma. Am J Surg Pathol. 2010;34:423-32 pubmed publisher
	Samuel J, Hendrix L. Laboratory maintenance of Coxiella burnetii. Curr Protoc Microbiol. 2009;Chapter 6:Unit 6C.1 pubmed publisher
	Krishnan C, Higgins J, West R, Natkunam Y, Heerema McKenney A, Arber D. Microtubule-associated protein-2 is a sensitive marker of primary and metastatic neuroblastoma. Am J Surg Pathol. 2009;33:1695-704 pubmed publisher
	Diez J, Caballero S, Belda F, Otegui M, Gajardo R, Jorquera J. Elimination capacity of a TSE-model agent in the manufacturing process of Alphanate/Fanhdi, a human factor VIII/VWF complex concentrate. Haemophilia. 2009;15:1249-57 pubmed publisher
	Nogueira P, Melão M, Lombardi A, Nogueira M, Vieira A. The effects of Anabaena spiroides exopolysaccharides on copper accumulation in an aquatic food chain. Aquat Toxicol. 2009;93:125-30 pubmed publisher
	Perreault F, Ait Ali N, Saison C, Popovic R, Juneau P. Dichromate effect on energy dissipation of photosystem II and photosystem I in Chlamydomonas reinhardtii. J Photochem Photobiol B. 2009;96:24-9 pubmed publisher
	Leonard B, Mastroeni D, Grover A, Liu Q, Yang K, Gao M, et al. Subventricular zone neural progenitors from rapid brain autopsies of elderly subjects with and without neurodegenerative disease. J Comp Neurol. 2009;515:269-94 pubmed publisher
	Francesconi A, Kumari R, Zukin R. Regulation of group I metabotropic glutamate receptor trafficking and signaling by the caveolar/lipid raft pathway. J Neurosci. 2009;29:3590-602 pubmed publisher
	Janex Habibi M, Huyard A, Esperanza M, Bruchet A. Reduction of endocrine disruptor emissions in the environment: the benefit of wastewater treatment. Water Res. 2009;43:1565-76 pubmed publisher
	Toyoshima M, Sakurai K, Shimazaki K, Takeda Y, Nakamoto M, Serizawa S, et al. Preferential localization of neural cell recognition molecule NB-2 in developing glutamatergic neurons in the rat auditory brainstem. J Comp Neurol. 2009;513:349-62 pubmed publisher
	Nogueira P, Melão M, Lombardi A, Nogueira M. Natural DOM affects copper speciation and bioavailability to bacteria and ciliate. Arch Environ Contam Toxicol. 2009;57:274-81 pubmed publisher
	Diniz Mendes L, Paula V, Luz S, Niel C. High prevalence of human Torque teno virus in streams crossing the city of Manaus, Brazilian Amazon. J Appl Microbiol. 2008;105:51-8 pubmed publisher
	Miagostovich M, Ferreira F, Guimarães F, Fumian T, Diniz Mendes L, Luz S, et al. Molecular detection and characterization of gastroenteritis viruses occurring naturally in the stream waters of Manaus, central Amazonia, Brazil. Appl Environ Microbiol. 2008;74:375-82 pubmed
	Pricelius S, Held C, Murkovic M, Bozic M, Kokol V, Cavaco Paulo A, et al. Enzymatic reduction of azo and indigoid compounds. Appl Microbiol Biotechnol. 2007;77:321-7 pubmed
	Ait Ali N, Juneau P, Didur O, Perreault F, Popovic R. Effect of dichromate on photosystem II activity in xanthophyll-deficient mutants of Chlamydomonas reinhardtii. Photosynth Res. 2008;95:45-53 pubmed
	Estrela A, Seixas A, Termignoni C. A cysteine endopeptidase from tick (Rhipicephalus (Boophilus) microplus) larvae with vitellin digestion activity. Comp Biochem Physiol B Biochem Mol Biol. 2007;148:410-6 pubmed
	Dewez D, Didur O, Vincent Héroux J, Popovic R. Validation of photosynthetic-fluorescence parameters as biomarkers for isoproturon toxic effect on alga Scenedesmus obliquus. Environ Pollut. 2008;151:93-100 pubmed
	Fenrich K, Skelton N, MacDermid V, Meehan C, Armstrong S, Neuber Hess M, et al. Axonal regeneration and development of de novo axons from distal dendrites of adult feline commissural interneurons after a proximal axotomy. J Comp Neurol. 2007;502:1079-97 pubmed
	Hasegawa A, Naruse M, Hitoshi S, Iwasaki Y, Takebayashi H, Ikenaka K. Regulation of glial development by cystatin C. J Neurochem. 2007;100:12-22 pubmed
	Fitzgerald D, Cole S, Hammond A, Seaman C, Cooper H. Characterization of neogenin-expressing neural progenitor populations and migrating neuroblasts in the embryonic mouse forebrain. Neuroscience. 2006;142:703-16 pubmed
	Peers G, Price N. Copper-containing plastocyanin used for electron transport by an oceanic diatom. Nature. 2006;441:341-4 pubmed
	Carmena D, Martinez J, Benito A, Guisantes J. Shared and non-shared antigens from three different extracts of the metacestode of Echinococcus granulosus. Mem Inst Oswaldo Cruz. 2005;100:861-7 pubmed
	Dubois E, Hennechart C, Deboosere N, Merle G, Legeay O, Burger C, et al. Intra-laboratory validation of a concentration method adapted for the enumeration of infectious F-specific RNA coliphage, enterovirus, and hepatitis A virus from inoculated leaves of salad vegetables. Int J Food Microbiol. 2006;108:164-71 pubmed
	Shin J, Fang Z, Yu Z, Wang C, Li S, Li X. Expression of mutant huntingtin in glial cells contributes to neuronal excitotoxicity. J Cell Biol. 2005;171:1001-12 pubmed
	Haney C, Buehler P, Gulati A. Synthesis and characterization of a novel DTPA polymerized hemoglobin based oxygen carrier. Biochim Biophys Acta. 2005;1725:358-69 pubmed
	Platts Mills J, Custis N, Woodfolk J, Platts Mills T. Airborne endotoxin in homes with domestic animals: implications for cat-specific tolerance. J Allergy Clin Immunol. 2005;116:384-9 pubmed
	Dewez D, Geoffroy L, Vernet G, Popovic R. Determination of photosynthetic and enzymatic biomarkers sensitivity used to evaluate toxic effects of copper and fludioxonil in alga Scenedesmus obliquus. Aquat Toxicol. 2005;74:150-9 pubmed
	de Jesus Ribeiro C, Ohara M, Gama P. Alternative model to human skin organ culture: a preliminary study with Leibovitz L15 medium. Microsc Res Tech. 2005;66:139-44 pubmed
	Pengchai P, Nakajima F, Furumai H. Estimation of origins of polycyclic aromatic hydrocarbons in size-fractionated road dust in Tokyo with multivariate analysis. Water Sci Technol. 2005;51:169-75 pubmed
	Platts Mills J, Custis N, Kenney A, Tsay A, Chapman M, Feldman S, et al. The effects of cage design on airborne allergens and endotoxin in animal rooms: high-volume measurements with an ion-charging device. Contemp Top Lab Anim Sci. 2005;44:12-6 pubmed
	Cowan A, Freeman M, Björkman P, Nicander B, Sitbon F, Tillberg E. Effects of senescence-induced alteration in cytokinin metabolism on source-sink relationships and ontogenic and stress-induced transitions in tobacco. Planta. 2005;221:801-14 pubmed

product information

Catalog Number :

MAB3418X

Subcategory :

Neuroscience

Product Name :

Anti-MAP2 Antibody, Alexa Fluor® 488 conjugated

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P11137

Host Name :

Mouse

Antigen :

MAP2

Clone :

AP20

Conjugate :

AlexaFluor®488

Isotype :

IgG1

Product Description :

Anti-MAP2 Antibody, Alexa Fluor® 488 conjugated

Cross Reactivity :

Bovine;Chicken;Human;Mouse;Rat

Immunogen :

Bovine brain microtubule protein.

Specificity :

Recognizes MAP-2 (microtubule associated protein-2). MAP-2 is one of several high molecular weight proteins that play an important role in brain microtubule assembly. In addition to its association with microtubules, MAP-2 associates with neurofilaments and actin filaments suggesting that it may guide interaction among microtubules, other cytoskeletal elements, and cytoplasmic organelles (1). MAP-2 is a stringent marker for neurons. In addition, MAP-2 displays intracellular specificity. In the central nervous system, MAP-2 is confined to neuronal cell bodies and dendrites. There are exceptions, however, where some axons stain positive for small amounts of MAP-2 (2,3). MAP-2 is uniformly distributed throughout the cell when first expressed in cultured neurons but becomes selectively localized as dendritic development proceeds (4,5). SDS-PAGE Profiles: In SDS-PAGE MAP-2 from adult rat migrates as a closely associated doublet having a molecular weight of approximately 300 kD. However, early in brain development (postnatal day 10 in rats), MAP-2 migrates as a single band that is identical to the lower molecular weight band of the adult MAP-2 doublet (MAP-2b). Later in development (postnatal days 17-18), the mobility of MAP-2 changes to the adult doublet form. (In the spinal cord, conversion to the adult form occurs earlier).

Package Size :

100 μg

Uses :

Immunohistochemistry

Storage :

Maintain for 1 year at 2–8°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.