This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
EMD Millipore
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
product type :
antibody
product name :
MAP2 Antibody, clone AP20, Alexa Fluor® 555 Conjugate
catalog :
MAB3418A5
quantity :
100 µL
clonality :
monoclonal
host :
mouse
conjugate :
Alexa Fluor 555
clone name :
AP20

The same clone is also sold as:
reactivity :
human, rat, chicken, bovine
application :
immunocytochemistry
citations: 68
Reference
Grande V, Manassero G, Vercelli A. Neuroprotective and anti-inflammatory roles of the phosphatase and tensin homolog deleted on chromosome Ten (PTEN) Inhibition in a Mouse Model of Temporal Lobe Epilepsy. PLoS ONE. 2014;9:e114554 pubmed publisher
Carlessi L, Fusar Poli E, Bechi G, Mantegazza M, Pascucci B, Narciso L, et al. Functional and molecular defects of hiPSC-derived neurons from patients with ATM deficiency. Cell Death Dis. 2014;5:e1342 pubmed publisher
Coimbra J, Collin S, Hart N. Topographic specializations in the retinal ganglion cell layer of Australian passerines. J Comp Neurol. 2014;522:3609-28 pubmed publisher
Griffin S, Brinkman N, Hedrick E, Rhodes E, Fout G. Comparison of nucleic acid extraction and reverse transcription-qPCR approaches for detection of GI and GII noroviruses in drinking water. J Virol Methods. 2014;199:76-85 pubmed publisher
Leusch F, Khan S, Gagnon M, Quayle P, Trinh T, Coleman H, et al. Assessment of wastewater and recycled water quality: a comparison of lines of evidence from in vitro, in vivo and chemical analyses. Water Res. 2014;50:420-31 pubmed publisher
Novaes J, Carvalho E. Reproduction, food dynamics and exploitation level of Oreochromis niloticus (Perciformes: Cichlidae) from artisanal fisheries in Barra Bonita Reservoir, Brazil. Rev Biol Trop. 2012;60:721-34 pubmed
Masclaux F, Hotz P, Friedli D, Savova Bianchi D, Oppliger A. High occurrence of hepatitis E virus in samples from wastewater treatment plants in Switzerland and comparison with other enteric viruses. Water Res. 2013;47:5101-9 pubmed publisher
Turaç G, Hindley C, Thomas R, Davis J, Deleidi M, Gasser T, et al. Combined flow cytometric analysis of surface and intracellular antigens reveals surface molecule markers of human neuropoiesis. PLoS ONE. 2013;8:e68519 pubmed publisher
Li L, Ginet V, Liu X, Vergun O, Tuittila M, Mathieu M, et al. The nNOS-p38MAPK pathway is mediated by NOS1AP during neuronal death. J Neurosci. 2013;33:8185-201 pubmed publisher
Arsenault J, Ferrari E, Niranjan D, Cuijpers S, Gu C, Vallis Y, et al. Stapling of the botulinum type A protease to growth factors and neuropeptides allows selective targeting of neuroendocrine cells. J Neurochem. 2013;126:223-33 pubmed publisher
Xu J, Nonogaki M, Madhira R, Ma H, Hermanson O, Kioussi C, et al. Population-specific regulation of Chmp2b by Lbx1 during onset of synaptogenesis in lateral association interneurons. PLoS ONE. 2012;7:e48573 pubmed publisher
De Keuckelaere A, Baert L, Duarte A, Stals A, Uyttendaele M. Evaluation of viral concentration methods from irrigation and processing water. J Virol Methods. 2013;187:294-303 pubmed publisher
Furutani Y, Kawasaki M, Matsuno H, Mitsui S, Mori K, Yoshihara Y. Vitronectin induces phosphorylation of ezrin/radixin/moesin actin-binding proteins through binding to its novel neuronal receptor telencephalin. J Biol Chem. 2012;287:39041-9 pubmed publisher
Karnas D, Mordel J, Bonnet D, Pevet P, Hicks D, Meissl H. Heterogeneity of intrinsically photosensitive retinal ganglion cells in the mouse revealed by molecular phenotyping. J Comp Neurol. 2013;521:912-32 pubmed publisher
Cai W, Carlson S, Brelsfoard J, Mannon C, Moncman C, Saatman K, et al. Rit GTPase signaling promotes immature hippocampal neuronal survival. J Neurosci. 2012;32:9887-97 pubmed publisher
Seidl A, Sanchez J, Schecterson L, Tabor K, Wang Y, Kashima D, et al. Transgenic quail as a model for research in the avian nervous system: a comparative study of the auditory brainstem. J Comp Neurol. 2013;521:5-23 pubmed publisher
Oukarroum A, Perreault F, Popovic R. Interactive effects of temperature and copper on photosystem II photochemistry in Chlorella vulgaris. J Photochem Photobiol B. 2012;110:9-14 pubmed publisher
Corrêa A, Rigotto C, Moresco V, Kleemann C, Teixeira A, Poli C, et al. The depuration dynamics of oysters (Crassostrea gigas) artificially contaminated with hepatitis A virus and human adenovirus. Mem Inst Oswaldo Cruz. 2012;107:11-7 pubmed
Abramowski D, Rabe S, Upadhaya A, Reichwald J, Danner S, Staab D, et al. Transgenic expression of intraneuronal A?42 but not A?40 leads to cellular A? lesions, degeneration, and functional impairment without typical Alzheimer's disease pathology. J Neurosci. 2012;32:1273-83 pubmed publisher
Killian R, Flippin J, Herrera C, Almenar Queralt A, Goldstein L. Kinesin light chain 1 suppression impairs human embryonic stem cell neural differentiation and amyloid precursor protein metabolism. PLoS ONE. 2012;7:e29755 pubmed publisher
Oukarroum A, Polchtchikov S, Perreault F, Popovic R. Temperature influence on silver nanoparticles inhibitory effect on photosystem II photochemistry in two green algae, Chlorella vulgaris and Dunaliella tertiolecta. Environ Sci Pollut Res Int. 2012;19:1755-62 pubmed publisher
Kroehne V, Freudenreich D, Hans S, Kaslin J, Brand M. Regeneration of the adult zebrafish brain from neurogenic radial glia-type progenitors. Development. 2011;138:4831-41 pubmed publisher
Borgesius N, de Waard M, van der Pluijm I, Omrani A, Zondag G, van der Horst G, et al. Accelerated age-related cognitive decline and neurodegeneration, caused by deficient DNA repair. J Neurosci. 2011;31:12543-53 pubmed publisher
Rhodes E, Hamilton D, See M, Wymer L. Evaluation of hollow-fiber ultrafiltration primary concentration of pathogens and secondary concentration of viruses from water. J Virol Methods. 2011;176:38-45 pubmed publisher
Tucker A, Driskell L, Pannell L, Wood D. Differential proteomic analysis of Rickettsia prowazekii propagated in diverse host backgrounds. Appl Environ Microbiol. 2011;77:4712-8 pubmed publisher
Novaes J, Carvalho E. Population structure and stock assessment of Hoplias malabaricus (Characiformes: Erythrinidae) caught by artisanal fishermen in river-reservoir transition area in Brazil. Rev Biol Trop. 2011;59:71-83 pubmed
Odraska P, Dolezalova L, Piler P, Oravec M, Blaha L. Utilization of the solid sorbent media in monitoring of airborne cyclophosphamide concentrations and the implications for occupational hygiene. J Environ Monit. 2011;13:1480-7 pubmed publisher
Aroeira R, Ribeiro J, Sebastião A, Valente C. Age-related changes of glycine receptor at the rat hippocampus: from the embryo to the adult. J Neurochem. 2011;118:339-53 pubmed publisher
Perreault F, Dionne J, Didur O, Juneau P, Popovic R. Effect of cadmium on photosystem II activity in Chlamydomonas reinhardtii: alteration of O-J-I-P fluorescence transients indicating the change of apparent activation energies within photosystem II. Photosynth Res. 2011;107:151-7 pubmed publisher
Alvarez Flores M, Furlin D, Ramos O, Balan A, Konno K, Chudzinski Tavassi A. Losac, the first hemolin that exhibits procogulant activity through selective factor X proteolytic activation. J Biol Chem. 2011;286:6918-28 pubmed publisher
Tabor K, Wong R, Rubel E. Topography and morphology of the inhibitory projection from superior olivary nucleus to nucleus laminaris in chickens (Gallus gallus). J Comp Neurol. 2011;519:358-75 pubmed publisher
Perreault F, Dewez D, Fortin C, Juneau P, Diallo A, Popovic R. Effect of aluminum on cellular division and photosynthetic electron transport in Euglena gracilis and Chlamydomonas acidophila. Environ Toxicol Chem. 2010;29:887-92 pubmed publisher
Terauchi A, Peers G, Kobayashi M, Niyogi K, Merchant S. Trophic status of Chlamydomonas reinhardtii influences the impact of iron deficiency on photosynthesis. Photosynth Res. 2010;105:39-49 pubmed publisher
Spigolon G, Veronesi C, Bonny C, Vercelli A. c-Jun N-terminal kinase signaling pathway in excitotoxic cell death following kainic acid-induced status epilepticus. Eur J Neurosci. 2010;31:1261-72 pubmed publisher
Petit A, Eullaffroy P, Debenest T, Gagné F. Toxicity of PAMAM dendrimers to Chlamydomonas reinhardtii. Aquat Toxicol. 2010;100:187-93 pubmed publisher
Dosnon Olette R, Trotel Aziz P, Couderchet M, Eullaffroy P. Fungicides and herbicide removal in Scenedesmus cell suspensions. Chemosphere. 2010;79:117-23 pubmed publisher
Jiang Z, Belforte J, Lu Y, Yabe Y, Pickel J, Smith C, et al. eIF2alpha Phosphorylation-dependent translation in CA1 pyramidal cells impairs hippocampal memory consolidation without affecting general translation. J Neurosci. 2010;30:2582-94 pubmed publisher
Sangoi A, McKenney J. A tissue microarray-based comparative analysis of novel and traditional immunohistochemical markers in the distinction between adrenal cortical lesions and pheochromocytoma. Am J Surg Pathol. 2010;34:423-32 pubmed publisher
Samuel J, Hendrix L. Laboratory maintenance of Coxiella burnetii. Curr Protoc Microbiol. 2009;Chapter 6:Unit 6C.1 pubmed publisher
Krishnan C, Higgins J, West R, Natkunam Y, Heerema McKenney A, Arber D. Microtubule-associated protein-2 is a sensitive marker of primary and metastatic neuroblastoma. Am J Surg Pathol. 2009;33:1695-704 pubmed publisher
Diez J, Caballero S, Belda F, Otegui M, Gajardo R, Jorquera J. Elimination capacity of a TSE-model agent in the manufacturing process of Alphanate/Fanhdi, a human factor VIII/VWF complex concentrate. Haemophilia. 2009;15:1249-57 pubmed publisher
Nogueira P, Melão M, Lombardi A, Nogueira M, Vieira A. The effects of Anabaena spiroides exopolysaccharides on copper accumulation in an aquatic food chain. Aquat Toxicol. 2009;93:125-30 pubmed publisher
Perreault F, Ait Ali N, Saison C, Popovic R, Juneau P. Dichromate effect on energy dissipation of photosystem II and photosystem I in Chlamydomonas reinhardtii. J Photochem Photobiol B. 2009;96:24-9 pubmed publisher
Leonard B, Mastroeni D, Grover A, Liu Q, Yang K, Gao M, et al. Subventricular zone neural progenitors from rapid brain autopsies of elderly subjects with and without neurodegenerative disease. J Comp Neurol. 2009;515:269-94 pubmed publisher
Francesconi A, Kumari R, Zukin R. Regulation of group I metabotropic glutamate receptor trafficking and signaling by the caveolar/lipid raft pathway. J Neurosci. 2009;29:3590-602 pubmed publisher
Janex Habibi M, Huyard A, Esperanza M, Bruchet A. Reduction of endocrine disruptor emissions in the environment: the benefit of wastewater treatment. Water Res. 2009;43:1565-76 pubmed publisher
Toyoshima M, Sakurai K, Shimazaki K, Takeda Y, Nakamoto M, Serizawa S, et al. Preferential localization of neural cell recognition molecule NB-2 in developing glutamatergic neurons in the rat auditory brainstem. J Comp Neurol. 2009;513:349-62 pubmed publisher
Nogueira P, Melão M, Lombardi A, Nogueira M. Natural DOM affects copper speciation and bioavailability to bacteria and ciliate. Arch Environ Contam Toxicol. 2009;57:274-81 pubmed publisher
Diniz Mendes L, Paula V, Luz S, Niel C. High prevalence of human Torque teno virus in streams crossing the city of Manaus, Brazilian Amazon. J Appl Microbiol. 2008;105:51-8 pubmed publisher
Miagostovich M, Ferreira F, Guimarães F, Fumian T, Diniz Mendes L, Luz S, et al. Molecular detection and characterization of gastroenteritis viruses occurring naturally in the stream waters of Manaus, central Amazonia, Brazil. Appl Environ Microbiol. 2008;74:375-82 pubmed
Pricelius S, Held C, Murkovic M, Bozic M, Kokol V, Cavaco Paulo A, et al. Enzymatic reduction of azo and indigoid compounds. Appl Microbiol Biotechnol. 2007;77:321-7 pubmed
Ait Ali N, Juneau P, Didur O, Perreault F, Popovic R. Effect of dichromate on photosystem II activity in xanthophyll-deficient mutants of Chlamydomonas reinhardtii. Photosynth Res. 2008;95:45-53 pubmed
Estrela A, Seixas A, Termignoni C. A cysteine endopeptidase from tick (Rhipicephalus (Boophilus) microplus) larvae with vitellin digestion activity. Comp Biochem Physiol B Biochem Mol Biol. 2007;148:410-6 pubmed
Dewez D, Didur O, Vincent Héroux J, Popovic R. Validation of photosynthetic-fluorescence parameters as biomarkers for isoproturon toxic effect on alga Scenedesmus obliquus. Environ Pollut. 2008;151:93-100 pubmed
Fenrich K, Skelton N, MacDermid V, Meehan C, Armstrong S, Neuber Hess M, et al. Axonal regeneration and development of de novo axons from distal dendrites of adult feline commissural interneurons after a proximal axotomy. J Comp Neurol. 2007;502:1079-97 pubmed
Hasegawa A, Naruse M, Hitoshi S, Iwasaki Y, Takebayashi H, Ikenaka K. Regulation of glial development by cystatin C. J Neurochem. 2007;100:12-22 pubmed
Fitzgerald D, Cole S, Hammond A, Seaman C, Cooper H. Characterization of neogenin-expressing neural progenitor populations and migrating neuroblasts in the embryonic mouse forebrain. Neuroscience. 2006;142:703-16 pubmed
Peers G, Price N. Copper-containing plastocyanin used for electron transport by an oceanic diatom. Nature. 2006;441:341-4 pubmed
Carmena D, Martinez J, Benito A, Guisantes J. Shared and non-shared antigens from three different extracts of the metacestode of Echinococcus granulosus. Mem Inst Oswaldo Cruz. 2005;100:861-7 pubmed
Dubois E, Hennechart C, Deboosere N, Merle G, Legeay O, Burger C, et al. Intra-laboratory validation of a concentration method adapted for the enumeration of infectious F-specific RNA coliphage, enterovirus, and hepatitis A virus from inoculated leaves of salad vegetables. Int J Food Microbiol. 2006;108:164-71 pubmed
Shin J, Fang Z, Yu Z, Wang C, Li S, Li X. Expression of mutant huntingtin in glial cells contributes to neuronal excitotoxicity. J Cell Biol. 2005;171:1001-12 pubmed
Haney C, Buehler P, Gulati A. Synthesis and characterization of a novel DTPA polymerized hemoglobin based oxygen carrier. Biochim Biophys Acta. 2005;1725:358-69 pubmed
Platts Mills J, Custis N, Woodfolk J, Platts Mills T. Airborne endotoxin in homes with domestic animals: implications for cat-specific tolerance. J Allergy Clin Immunol. 2005;116:384-9 pubmed
Dewez D, Geoffroy L, Vernet G, Popovic R. Determination of photosynthetic and enzymatic biomarkers sensitivity used to evaluate toxic effects of copper and fludioxonil in alga Scenedesmus obliquus. Aquat Toxicol. 2005;74:150-9 pubmed
de Jesus Ribeiro C, Ohara M, Gama P. Alternative model to human skin organ culture: a preliminary study with Leibovitz L15 medium. Microsc Res Tech. 2005;66:139-44 pubmed
Pengchai P, Nakajima F, Furumai H. Estimation of origins of polycyclic aromatic hydrocarbons in size-fractionated road dust in Tokyo with multivariate analysis. Water Sci Technol. 2005;51:169-75 pubmed
Platts Mills J, Custis N, Kenney A, Tsay A, Chapman M, Feldman S, et al. The effects of cage design on airborne allergens and endotoxin in animal rooms: high-volume measurements with an ion-charging device. Contemp Top Lab Anim Sci. 2005;44:12-6 pubmed
Cowan A, Freeman M, Björkman P, Nicander B, Sitbon F, Tillberg E. Effects of senescence-induced alteration in cytokinin metabolism on source-sink relationships and ontogenic and stress-induced transitions in tobacco. Planta. 2005;221:801-14 pubmed
product information
Catalog Number :
MAB3418A5
Subcategory :
Neuroscience
Product Name :
Anti-MAP2 Antibody, clone AP20, Alexa Fluor® 555 Conjugate
Product Type :
Antibodies
Clonality :
Monoclonal Antibody
Gene ID :
P11137
Host Name :
Mouse
Antigen :
MAP2
Clone :
AP20
Conjugate :
AlexaFluor®555
Isotype :
IgG
Product Description :
Anti-MAP2 Antibody, clone AP20, Alexa Fluor® 555 Conjugate
Cross Reactivity :
Rat;Bovine;Chicken;Human;Mouse
Background :
The microtubule-associated protein 2 (MAP-2) is an abundant neuronal cytoskeletal protein that binds to tubulin, stabilizes microtubules (Herzog and Weber, 1978), and is an excellent marker for neurons. MAP-2 is essential for the development and maintenance of neuronal morphology (Matus, 1991). Three primary isoforms of MAP-2, the high molecular weight MAP2a and MAP2b, and the low molecular weight MAP2c (resulting from alternate splicing of the MAP2 gene), have been identified in neurons. (Chung et al., 1996). The low molecular weight isoform, MAP2c, is expressed in developing brain and is down-regulated during brain maturation, whereas the high molecular weight MAP2b is expressed in both developing and adult brain. The MAP2a appears only after brain maturation (Tucker, 1990). All these forms bind to microtubules through a domain near the carboxyl terminus that contains either three or four similar repeats of a 31-amino-acid motif (Lewis et al., 1988). MAP-2 together with MAP-4 and tau proteins belong to the family of thermostable proteins associated with microtubules.
ALT Names :
Microtubule-associated protein 2;MAP-2;MAP2
Immunogen :
Bovine brain microtubule protein
Package Size :
100 µL
Uses :
Immunocytochemistry
Storage :
Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.
company information
EMD Millipore
290 Concord Road
Billerica, Massachusetts 01821
bioscienceshelp@emdchemical.com
https://www.emdmillipore.com
888-854-3417
headquarters: United States
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

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