This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
EMD Millipore
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
product type :
antibody
product name :
MAP2 Antibody, clone AP20
catalog :
MAB3418
quantity :
200 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
AP20

The same clone is also sold as:
reactivity :
human, mouse, rat, dogs, chicken, bovine
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, immunohistochemistry - free floating section
citations: 199
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - frozen section; mouse; loading ...; fig s4f
  • immunocytochemistry; mouse; loading ...; fig 2a
  • immunocytochemistry; human; loading ...; fig s3d
Qian H, Kang X, Hu J, Zhang D, Liang Z, Meng F, et al. Reversing a model of Parkinson's disease with in situ converted nigral neurons. Nature. 2020;582:550-556 pubmed publisher
  • immunocytochemistry; human; 1:200; fig 7e
  • western blot; human; 1:1000; fig 1c
Menon V, Thomas R, Elgueta C, Horl M, Osborn T, Hallett P, et al. Comprehensive Cell Surface Antigen Analysis Identifies Transferrin Receptor Protein-1 (CD71) as a Negative Selection Marker for Human Neuronal Cells. Stem Cells. 2019;37:1293-1306 pubmed publisher
  • immunohistochemistry; mouse; 1:200; loading ...; fig 5s1a
Jang M, Gould E, Xu J, Kim E, Kim J. Oligodendrocytes regulate presynaptic properties and neurotransmission through BDNF signaling in the mouse brainstem. elife. 2019;8: pubmed publisher
  • immunohistochemistry; mouse; 1:500; loading ...; fig s1b
Montalbán Loro R, Lozano Ureña A, Ito M, Krueger C, Reik W, Ferguson Smith A, et al. TET3 prevents terminal differentiation of adult NSCs by a non-catalytic action at Snrpn. Nat Commun. 2019;10:1726 pubmed publisher
  • immunocytochemistry; human; loading ...; fig s1l
Wang C, Najm R, Xu Q, Jeong D, Walker D, Balestra M, et al. Gain of toxic apolipoprotein E4 effects in human iPSC-derived neurons is ameliorated by a small-molecule structure corrector. Nat Med. 2018;24:647-657 pubmed publisher
  • immunocytochemistry; mouse; loading ...; fig 2b, s5e
Jacko M, Weyn Vanhentenryck S, Smerdon J, Yan R, Feng H, Williams D, et al. Rbfox Splicing Factors Promote Neuronal Maturation and Axon Initial Segment Assembly. Neuron. 2018;97:853-868.e6 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:500; loading ...; fig 5a
Gant J, Blalock E, Chen K, Kadish I, Thibault O, Porter N, et al. FK506-Binding Protein 12.6/1b, a Negative Regulator of [Ca2+], Rescues Memory and Restores Genomic Regulation in the Hippocampus of Aging Rats. J Neurosci. 2018;38:1030-1041 pubmed publisher
  • immunohistochemistry - frozen section; chicken; 1:1000; loading ...; tbl 1
  • western blot; chicken; 1:1000; loading ...; tbl 1
Sakano H, Zorio D, Wang X, Ting Y, Noble W, MacCoss M, et al. Proteomic analyses of nucleus laminaris identified candidate targets of the fragile X mental retardation protein. J Comp Neurol. 2017;525:3341-3359 pubmed publisher
  • immunocytochemistry; rat; loading ...; fig 2a
Latina V, Caioli S, Zona C, Ciotti M, Amadoro G, Calissano P. Impaired NGF/TrkA Signaling Causes Early AD-Linked Presynaptic Dysfunction in Cholinergic Primary Neurons. Front Cell Neurosci. 2017;11:68 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig s1f
Niu Y, Dai Z, Liu W, Zhang C, Yang Y, Guo Z, et al. Ablation of SNX6 leads to defects in synaptic function of CA1 pyramidal neurons and spatial memory. elife. 2017;6: pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:500; fig 4a
Monaghan C, Nechiporuk T, Jeng S, McWeeney S, Wang J, Rosenfeld M, et al. REST corepressors RCOR1 and RCOR2 and the repressor INSM1 regulate the proliferation-differentiation balance in the developing brain. Proc Natl Acad Sci U S A. 2017;114:E406-E415 pubmed publisher
  • immunocytochemistry; mouse; 1:50; fig s1f
  • western blot; mouse; 1:1000; fig s1e
Kim B, Shin H, Goto J, Carp R, Choi E, Kim Y. Cellular Prion Protein Combined with Galectin-3 and -6 Affects the Infectivity Titer of an Endogenous Retrovirus Assayed in Hippocampal Neuronal Cells. PLoS ONE. 2016;11:e0167293 pubmed publisher
  • western blot; mouse; 1:1000; fig 2c
Lee P, Goh W, Sng J. Network-based characterization of the synaptic proteome reveals that removal of epigenetic regulator Prmt8 restricts proteins associated with synaptic maturation. J Neurochem. 2017;140:613-628 pubmed publisher
  • immunohistochemistry - frozen section; mouse; loading ...; fig 1a
Weatherstone J, Kopp Scheinpflug C, Pilati N, Wang Y, Forsythe I, Rubel E, et al. Maintenance of neuronal size gradient in MNTB requires sound-evoked activity. J Neurophysiol. 2017;117:756-766 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:400; loading ...
Bosch P, Fuller L, Sleeth C, Weiner J. Akirin2 is essential for the formation of the cerebral cortex. Neural Dev. 2016;11:21 pubmed
  • immunocytochemistry; human; 1:1000; fig 2
  • western blot; human; fig 5
Xue Y, Qian H, Hu J, Zhou B, Zhou Y, Hu X, et al. Sequential regulatory loops as key gatekeepers for neuronal reprogramming in human cells. Nat Neurosci. 2016;19:807-15 pubmed publisher
  • immunocytochemistry; rat; 1:500; loading ...; tbl 3
Bartelt Kirbach B, Moron M, Glomb M, Beck C, Weller M, Golenhofen N. HspB5/?B-crystallin increases dendritic complexity and protects the dendritic arbor during heat shock in cultured rat hippocampal neurons. Cell Mol Life Sci. 2016;73:3761-75 pubmed publisher
  • western blot; human; 1:1000; fig s3
Wang Y, Jones Tabah J, Chakravarty P, Stewart A, Muotri A, Laposa R, et al. Pharmacological Bypass of Cockayne Syndrome B Function in Neuronal Differentiation. Cell Rep. 2016;14:2554-61 pubmed publisher
  • immunocytochemistry; mouse; fig 4a
Ryu J, Hong B, Kim Y, Yang E, Choi M, Kim H, et al. Neuregulin-1 attenuates cognitive function impairments in a transgenic mouse model of Alzheimer's disease. Cell Death Dis. 2016;7:e2117 pubmed publisher
  • western blot; human; fig 5c
Kim D, Jung J, You E, Ko P, Oh S, Rhee S. mDia1 regulates breast cancer invasion by controlling membrane type 1-matrix metalloproteinase localization. Oncotarget. 2016;7:17829-43 pubmed publisher
  • immunocytochemistry; mouse; 1:2000; fig 5
Liu A, Zhou Z, Dang R, Zhu Y, Qi J, He G, et al. Neuroligin 1 regulates spines and synaptic plasticity via LIMK1/cofilin-mediated actin reorganization. J Cell Biol. 2016;212:449-63 pubmed publisher
  • immunocytochemistry; rat; 1:1000; loading ...; fig s2a
Eckenstaler R, Lessmann V, Brigadski T. CAPS1 effects on intragranular pH and regulation of BDNF release from secretory granules in hippocampal neurons. J Cell Sci. 2016;129:1378-90 pubmed publisher
  • immunocytochemistry; human; fig 5
Rooney G, Goodwin A, Depeille P, Sharir A, Schofield C, Yeh E, et al. Human iPS Cell-Derived Neurons Uncover the Impact of Increased Ras Signaling in Costello Syndrome. J Neurosci. 2016;36:142-52 pubmed publisher
  • immunocytochemistry; human; 1:200; fig 5
Pellett S, Schwartz M, Tepp W, Josephson R, Scherf J, Pier C, et al. Human Induced Pluripotent Stem Cell Derived Neuronal Cells Cultured on Chemically-Defined Hydrogels for Sensitive In Vitro Detection of Botulinum Neurotoxin. Sci Rep. 2015;5:14566 pubmed publisher
  • western blot; rat; 1:1000
Tang H, Hua F, Wang J, Yousuf S, Atif F, Sayeed I, et al. Progesterone and vitamin D combination therapy modulates inflammatory response after traumatic brain injury. Brain Inj. 2015;29:1165-1174 pubmed publisher
  • immunocytochemistry; rat; 1:100
Tang N, Lyu D, Liu T, Chen F, Jing S, Hao T, et al. Different Effects of p52SHC1 and p52SHC3 on the Cell Cycle of Neurons and Neural Stem Cells. J Cell Physiol. 2016;231:172-80 pubmed publisher
  • western blot; mouse; 1 ug/ml; fig s2
Koh H, Chang C, Jeon S, Yoon H, Ahn Y, Kim H, et al. The HIF-1/glial TIM-3 axis controls inflammation-associated brain damage under hypoxia. Nat Commun. 2015;6:6340 pubmed publisher
  • immunohistochemistry; mouse
Weinert M, Selvakumar T, Tierney T, Alavian K. Isolation, culture and long-term maintenance of primary mesencephalic dopaminergic neurons from embryonic rodent brains. J Vis Exp. 2015;: pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:200; fig 2
Nagai J, Kitamura Y, Owada K, Yamashita N, Takei K, Goshima Y, et al. Crmp4 deletion promotes recovery from spinal cord injury by neuroprotection and limited scar formation. Sci Rep. 2015;5:8269 pubmed publisher
  • immunocytochemistry; human; 1:250
  • immunocytochemistry; mouse; 1:250
Wan C, O Carroll S, Kim S, Green C, Nicholson L. Spatiotemporal changes in Cx30 and Cx43 expression during neuronal differentiation of P19 EC and NT2/D1 cells. Cell Biol Int Rep (2010). 2013;20:13-23 pubmed
  • immunohistochemistry; mouse; 1:200
Grande V, Manassero G, Vercelli A. Neuroprotective and anti-inflammatory roles of the phosphatase and tensin homolog deleted on chromosome Ten (PTEN) Inhibition in a Mouse Model of Temporal Lobe Epilepsy. PLoS ONE. 2014;9:e114554 pubmed publisher
  • immunocytochemistry; human
Pamies D, Bal Price A, Fabbri M, Gribaldo L, Scelfo B, Harris G, et al. Silencing of PNPLA6, the neuropathy target esterase (NTE) codifying gene, alters neurodifferentiation of human embryonal carcinoma stem cells (NT2). Neuroscience. 2014;281:54-67 pubmed publisher
  • immunocytochemistry; human; 1:200; loading ...; fig 1b
Lee H, Kim K, Lim H, Choi M, Kim H, Ahn H, et al. Priming Wharton's jelly-derived mesenchymal stromal/stem cells with ROCK inhibitor improves recovery in an intracerebral hemorrhage model. J Cell Biochem. 2015;116:310-9 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:200
Greene C, Green C, Sherwin T. Transdifferentiation of chondrocytes into neuron-like cells induced by neuronal lineage specifying growth factors. Cell Biol Int. 2015;39:185-91 pubmed publisher
  • immunocytochemistry; rat; 1:1000
Stansfield K, Bichell T, Bowman A, Guilarte T. BDNF and Huntingtin protein modifications by manganese: implications for striatal medium spiny neuron pathology in manganese neurotoxicity. J Neurochem. 2014;131:655-66 pubmed publisher
  • immunocytochemistry; human
  • western blot; human
Carlessi L, Fusar Poli E, Bechi G, Mantegazza M, Pascucci B, Narciso L, et al. Functional and molecular defects of hiPSC-derived neurons from patients with ATM deficiency. Cell Death Dis. 2014;5:e1342 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:500; fig s10
Lu T, Aron L, Zullo J, Pan Y, Kim H, Chen Y, et al. REST and stress resistance in ageing and Alzheimer's disease. Nature. 2014;507:448-54 pubmed publisher
  • immunohistochemistry - free floating section; mouse; 1:500
Markkanen M, Karhunen T, Llano O, Ludwig A, Rivera C, Uvarov P, et al. Distribution of neuronal KCC2a and KCC2b isoforms in mouse CNS. J Comp Neurol. 2014;522:1897-914 pubmed publisher
  • immunocytochemistry; mouse; 1:1000
Stenfeldt C, Pacheco J, Rodriguez L, Arzt J. Infection dynamics of foot-and-mouth disease virus in pigs using two novel simulated-natural inoculation methods. Res Vet Sci. 2014;96:396-405 pubmed publisher
  • western blot; mouse; 1:2500
Morris D, Pearson R, Cormican P, Kenny E, O Dushlaine C, Perreault L, et al. An inherited duplication at the gene p21 Protein-Activated Kinase 7 (PAK7) is a risk factor for psychosis. Hum Mol Genet. 2014;23:3316-26 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:200
Greene C, Chang C, Fraser C, Nelidova D, Chen J, Lim A, et al. Cells from the adult corneal stroma can be reprogrammed to a neuron-like cell using exogenous growth factors. Exp Cell Res. 2014;322:122-32 pubmed publisher
  • immunocytochemistry; mouse; 1:300
Azari H. Isolation and enrichment of defined neural cell populations from heterogeneous neural stem cell progeny. Methods Mol Biol. 2013;1059:95-106 pubmed publisher
  • flow cytometry; human; 1:500
  • immunocytochemistry; human
  • flow cytometry; mouse
  • immunocytochemistry; mouse
Turaç G, Hindley C, Thomas R, Davis J, Deleidi M, Gasser T, et al. Combined flow cytometric analysis of surface and intracellular antigens reveals surface molecule markers of human neuropoiesis. PLoS ONE. 2013;8:e68519 pubmed publisher
  • immunocytochemistry; human; 1:500
  • western blot; human; 1:3000
Arsenault J, Ferrari E, Niranjan D, Cuijpers S, Gu C, Vallis Y, et al. Stapling of the botulinum type A protease to growth factors and neuropeptides allows selective targeting of neuroendocrine cells. J Neurochem. 2013;126:223-33 pubmed publisher
  • western blot; mouse; 1:1000
Oshikawa M, Okada K, Nakajima K, Ajioka I. Cortical excitatory neurons become protected from cell division during neurogenesis in an Rb family-dependent manner. Development. 2013;140:2310-20 pubmed publisher
  • immunocytochemistry; rat; 1:200
  • immunohistochemistry; rat; 1:2000
Arguello A, Ye X, Bozdagi O, Pollonini G, Tronel S, Bambah Mukku D, et al. CCAAT enhancer binding protein ? plays an essential role in memory consolidation and reconsolidation. J Neurosci. 2013;33:3646-58 pubmed publisher
  • immunohistochemistry - frozen section; mouse
Xu J, Nonogaki M, Madhira R, Ma H, Hermanson O, Kioussi C, et al. Population-specific regulation of Chmp2b by Lbx1 during onset of synaptogenesis in lateral association interneurons. PLoS ONE. 2012;7:e48573 pubmed publisher
  • immunohistochemistry - frozen section; dogs; 1:300
  • immunocytochemistry; dogs; 1:300
Walton R, Parmentier T, Wolfe J. Postnatal neural precursor cell regions in the rostral subventricular zone, hippocampal subgranular zone and cerebellum of the dog (Canis lupus familiaris). Histochem Cell Biol. 2013;139:415-29 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:200
Nasonkin I, Lazo K, Hambright D, Brooks M, Fariss R, Swaroop A. Distinct nuclear localization patterns of DNA methyltransferases in developing and mature mammalian retina. J Comp Neurol. 2011;519:1914-30 pubmed publisher
  • immunohistochemistry - free floating section; mouse; 1:1000
Wang Y, Cunningham D, Tempel B, Rubel E. Compartment-specific regulation of plasma membrane calcium ATPase type 2 in the chick auditory brainstem. J Comp Neurol. 2009;514:624-40 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:1000
Toyoshima M, Sakurai K, Shimazaki K, Takeda Y, Nakamoto M, Serizawa S, et al. Preferential localization of neural cell recognition molecule NB-2 in developing glutamatergic neurons in the rat auditory brainstem. J Comp Neurol. 2009;513:349-62 pubmed publisher
  • immunohistochemistry - free floating section; rat; 1:500
  • western blot; rat; 1:500
Papadeas S, Halloran C, McCown T, Breese G, Blake B. Changes in apical dendritic structure correlate with sustained ERK1/2 phosphorylation in medial prefrontal cortex of a rat model of dopamine D1 receptor agonist sensitization. J Comp Neurol. 2008;511:271-85 pubmed publisher
  • immunohistochemistry; human
Ponti G, Peretto P, Bonfanti L. Genesis of neuronal and glial progenitors in the cerebellar cortex of peripuberal and adult rabbits. PLoS ONE. 2008;3:e2366 pubmed publisher
  • immunocytochemistry; rat; 1:1000
King A, Chung R, Vickers J, Dickson T. Localization of glutamate receptors in developing cortical neurons in culture and relationship to susceptibility to excitotoxicity. J Comp Neurol. 2006;498:277-94 pubmed
  • immunohistochemistry - frozen section; mouse; 1:2000
Blanchart A, De Carlos J, López Mascaraque L. Time frame of mitral cell development in the mice olfactory bulb. J Comp Neurol. 2006;496:529-43 pubmed
Botté A, Laine J, Xicota L, Heiligenstein X, Fontaine G, Kasri A, et al. Ultrastructural and dynamic studies of the endosomal compartment in Down syndrome. Acta Neuropathol Commun. 2020;8:89 pubmed publisher
Maslon M, Braunschweig U, Aitken S, Mann A, Kilanowski F, Hunter C, et al. A slow transcription rate causes embryonic lethality and perturbs kinetic coupling of neuronal genes. EMBO J. 2019;38: pubmed publisher
Park S, Mansur R, Lee Y, Lee J, Seo M, Choi A, et al. Liraglutide Activates mTORC1 Signaling and AMPA Receptors in Rat Hippocampal Neurons Under Toxic Conditions. Front Neurosci. 2018;12:756 pubmed publisher
Xia W, Su L, Jiao J. Cold-induced protein RBM3 orchestrates neurogenesis via modulating Yap mRNA stability in cold stress. J Cell Biol. 2018;217:3464-3479 pubmed publisher
Zuo X, Hou Q, Jin J, Chen X, Zhan L, Tang Y, et al. Inhibition of Cathepsins B Induces Neuroprotection Against Secondary Degeneration in Ipsilateral Substantia Nigra After Focal Cortical Infarction in Adult Male Rats. Front Aging Neurosci. 2018;10:125 pubmed publisher
Singh M, Miura P, Renden R. Age-related defects in short-term plasticity are reversed by acetyl-L-carnitine at the mouse calyx of Held. Neurobiol Aging. 2018;67:108-119 pubmed publisher
Torres L, Robinson S, Kim D, Yan A, Cleland T, Bynoe M. Toxoplasma gondii alters NMDAR signaling and induces signs of Alzheimer's disease in wild-type, C57BL/6 mice. J Neuroinflammation. 2018;15:57 pubmed publisher
Tan V, Mockett B, Ohline S, Parfitt K, Wicky H, Peppercorn K, et al. Lentivirus-mediated expression of human secreted amyloid precursor protein-alpha prevents development of memory and plasticity deficits in a mouse model of Alzheimer's disease. Mol Brain. 2018;11:7 pubmed publisher
Oda S, Tsuneoka Y, Yoshida S, Adachi Akahane S, Ito M, Kuroda M, et al. Immunolocalization of muscarinic M1 receptor in the rat medial prefrontal cortex. J Comp Neurol. 2018;526:1329-1350 pubmed publisher
Klein Z, Takahashi H, Ma M, Stagi M, Zhou M, Lam T, et al. Loss of TMEM106B Ameliorates Lysosomal and Frontotemporal Dementia-Related Phenotypes in Progranulin-Deficient Mice. Neuron. 2017;95:281-296.e6 pubmed publisher
Rotem N, Magen I, Ionescu A, Gershoni Emek N, Altman T, Costa C, et al. ALS Along the Axons - Expression of Coding and Noncoding RNA Differs in Axons of ALS models. Sci Rep. 2017;7:44500 pubmed publisher
Zhang J, Michel U, Lenz C, Friedel C, Köster S, D Hedouville Z, et al. Calpain-mediated cleavage of collapsin response mediator protein-2 drives acute axonal degeneration. Sci Rep. 2016;6:37050 pubmed publisher
Rotschafer S, Allen Sharpley M, Cramer K. Axonal Cleaved Caspase-3 Regulates Axon Targeting and Morphogenesis in the Developing Auditory Brainstem. Front Neural Circuits. 2016;10:84 pubmed
Flores B, Dulchavsky M, Krans A, Sawaya M, Paulson H, Todd P, et al. Distinct C9orf72-Associated Dipeptide Repeat Structures Correlate with Neuronal Toxicity. PLoS ONE. 2016;11:e0165084 pubmed publisher
Vogt J, Yang J, Mobascher A, Cheng J, Li Y, Liu X, et al. Molecular cause and functional impact of altered synaptic lipid signaling due to a prg-1 gene SNP. EMBO Mol Med. 2016;8:25-38 pubmed publisher
Choi S, Kim D, Kam T, Yun S, Kim S, Park H, et al. Lysosomal Enzyme Glucocerebrosidase Protects against Aβ1-42 Oligomer-Induced Neurotoxicity. PLoS ONE. 2015;10:e0143854 pubmed publisher
Suberbielle E, Djukic B, Evans M, Kim D, Taneja P, Wang X, et al. DNA repair factor BRCA1 depletion occurs in Alzheimer brains and impairs cognitive function in mice. Nat Commun. 2015;6:8897 pubmed publisher
Beaudet M, Yang Q, Cadau S, Blais M, Bellenfant S, Gros Louis F, et al. High yield extraction of pure spinal motor neurons, astrocytes and microglia from single embryo and adult mouse spinal cord. Sci Rep. 2015;5:16763 pubmed publisher
Baek S, Copeland B, Yun E, Kwon S, Guemez Gamboa A, Schaffer A, et al. An AKT3-FOXG1-reelin network underlies defective migration in human focal malformations of cortical development. Nat Med. 2015;21:1445-54 pubmed publisher
Yuan Y, Seong E, Yuan L, Singh D, Arikkath J. Differential regulation of apical-basolateral dendrite outgrowth by activity in hippocampal neurons. Front Cell Neurosci. 2015;9:314 pubmed publisher
Velazquez F, Prucca C, Etienne O, D Astolfo D, Silvestre D, Boussin F, et al. Brain development is impaired in c-fos -/- mice. Oncotarget. 2015;6:16883-901 pubmed
Shields L, Kim H, Zhu L, Haddad D, Berthet A, Pathak D, et al. Dynamin-related protein 1 is required for normal mitochondrial bioenergetic and synaptic function in CA1 hippocampal neurons. Cell Death Dis. 2015;6:e1725 pubmed publisher
Minami S, Min S, Krabbe G, Wang C, Zhou Y, Asgarov R, et al. Progranulin protects against amyloid β deposition and toxicity in Alzheimer's disease mouse models. Nat Med. 2014;20:1157-64 pubmed publisher
Choschzick I, Hirseland E, Cramer H, Schultz S, Leppert J, Tronnier V, et al. Responsiveness of stem-like human glioma cells to all-trans retinoic acid and requirement of retinoic acid receptor isotypes α, β and γ. Neuroscience. 2014;279:44-64 pubmed publisher
Finn R, Evans C, Lee L. Strain-dependent brain defects in mouse models of primary ciliary dyskinesia with mutations in Pcdp1 and Spef2. Neuroscience. 2014;277:552-67 pubmed publisher
Wang Y, Huang Y, Zhao L, Li Y, Zheng J. Glutaminase 1 is essential for the differentiation, proliferation, and survival of human neural progenitor cells. Stem Cells Dev. 2014;23:2782-90 pubmed publisher
Coimbra J, Collin S, Hart N. Topographic specializations in the retinal ganglion cell layer of Australian passerines. J Comp Neurol. 2014;522:3609-28 pubmed publisher
Farg M, Sundaramoorthy V, Sultana J, Yang S, Atkinson R, Levina V, et al. C9ORF72, implicated in amytrophic lateral sclerosis and frontotemporal dementia, regulates endosomal trafficking. Hum Mol Genet. 2014;23:3579-95 pubmed publisher
Griffin S, Brinkman N, Hedrick E, Rhodes E, Fout G. Comparison of nucleic acid extraction and reverse transcription-qPCR approaches for detection of GI and GII noroviruses in drinking water. J Virol Methods. 2014;199:76-85 pubmed publisher
Bershteyn M, Hayashi Y, Desachy G, Hsiao E, Sami S, Tsang K, et al. Cell-autonomous correction of ring chromosomes in human induced pluripotent stem cells. Nature. 2014;507:99-103 pubmed publisher
Wang Y, Sakano H, Beebe K, Brown M, de Laat R, Bothwell M, et al. Intense and specialized dendritic localization of the fragile X mental retardation protein in binaural brainstem neurons: a comparative study in the alligator, chicken, gerbil, and human. J Comp Neurol. 2014;522:2107-28 pubmed publisher
Leusch F, Khan S, Gagnon M, Quayle P, Trinh T, Coleman H, et al. Assessment of wastewater and recycled water quality: a comparison of lines of evidence from in vitro, in vivo and chemical analyses. Water Res. 2014;50:420-31 pubmed publisher
Hsieh J, Wang H, Chang S, Liao K, Lee I, Lin W, et al. Mesenchymal stem cells from human umbilical cord express preferentially secreted factors related to neuroprotection, neurogenesis, and angiogenesis. PLoS ONE. 2013;8:e72604 pubmed publisher
Chan W, Sideris A, Sutachan J, Montoya G J, Blanck T, Recio Pinto E. Differential regulation of proliferation and neuronal differentiation in adult rat spinal cord neural stem/progenitors by ERK1/2, Akt, and PLC?. Front Mol Neurosci. 2013;6:23 pubmed publisher
Azizi S, Krynska B. Derivation of neuronal cells from fetal normal human astrocytes (NHA). Methods Mol Biol. 2013;1078:89-96 pubmed publisher
Novaes J, Carvalho E. Reproduction, food dynamics and exploitation level of Oreochromis niloticus (Perciformes: Cichlidae) from artisanal fisheries in Barra Bonita Reservoir, Brazil. Rev Biol Trop. 2012;60:721-34 pubmed
Masclaux F, Hotz P, Friedli D, Savova Bianchi D, Oppliger A. High occurrence of hepatitis E virus in samples from wastewater treatment plants in Switzerland and comparison with other enteric viruses. Water Res. 2013;47:5101-9 pubmed publisher
Jain T, Wager Miller J, Mackie K, Straiker A. Diacylglycerol lipase? (DAGL?) and DAGL? cooperatively regulate the production of 2-arachidonoyl glycerol in autaptic hippocampal neurons. Mol Pharmacol. 2013;84:296-302 pubmed publisher
Li L, Ginet V, Liu X, Vergun O, Tuittila M, Mathieu M, et al. The nNOS-p38MAPK pathway is mediated by NOS1AP during neuronal death. J Neurosci. 2013;33:8185-201 pubmed publisher
García Parra P, Maroto M, Cavaliere F, Naldaiz Gastesi N, Alava J, Garcia A, et al. A neural extracellular matrix-based method for in vitro hippocampal neuron culture and dopaminergic differentiation of neural stem cells. BMC Neurosci. 2013;14:48 pubmed publisher
Guo H, Zhao Z, Yang Q, Wang M, Bell R, Wang S, et al. An activated protein C analog stimulates neuronal production by human neural progenitor cells via a PAR1-PAR3-S1PR1-Akt pathway. J Neurosci. 2013;33:6181-90 pubmed publisher
Mercati O, Danckaert A, André Leroux G, Bellinzoni M, Gouder L, Watanabe K, et al. Contactin 4, -5 and -6 differentially regulate neuritogenesis while they display identical PTPRG binding sites. Biol Open. 2013;2:324-34 pubmed publisher
Takase K, Oda S, Kuroda M, Funato H. Monoaminergic and neuropeptidergic neurons have distinct expression profiles of histone deacetylases. PLoS ONE. 2013;8:e58473 pubmed publisher
Falcão A, Silva R, Vaz A, Silva S, Fernandes A, Brites D. Cross-talk between neurons and astrocytes in response to bilirubin: early beneficial effects. Neurochem Res. 2013;38:644-59 pubmed publisher
Nair R, Lauks J, Jung S, Cooke N, de Wit H, Brose N, et al. Neurobeachin regulates neurotransmitter receptor trafficking to synapses. J Cell Biol. 2013;200:61-80 pubmed publisher
Mariano C, Palmela I, Pereira P, Fernandes A, Falcão A, Cardoso F, et al. Tricellulin expression in brain endothelial and neural cells. Cell Tissue Res. 2013;351:397-407 pubmed publisher
De Keuckelaere A, Baert L, Duarte A, Stals A, Uyttendaele M. Evaluation of viral concentration methods from irrigation and processing water. J Virol Methods. 2013;187:294-303 pubmed publisher
Liu Y, Staal J, Canty A, Kirkcaldie M, King A, Bibari O, et al. Cytoskeletal changes during development and aging in the cortex of neurofilament light protein knockout mice. J Comp Neurol. 2013;521:1817-27 pubmed publisher
Puttonen K, Ruponen M, Kauppinen R, Wojciechowski S, Hovatta O, Koistinaho J. Improved method of producing human neural progenitor cells of high purity and in large quantities from pluripotent stem cells for transplantation studies. Cell Transplant. 2013;22:1753-66 pubmed publisher
Wu Q, Hwang C, Zheng H, Wagley Y, Lin H, Kim D, et al. MicroRNA 339 down-regulates ?-opioid receptor at the post-transcriptional level in response to opioid treatment. FASEB J. 2013;27:522-35 pubmed publisher
Furutani Y, Kawasaki M, Matsuno H, Mitsui S, Mori K, Yoshihara Y. Vitronectin induces phosphorylation of ezrin/radixin/moesin actin-binding proteins through binding to its novel neuronal receptor telencephalin. J Biol Chem. 2012;287:39041-9 pubmed publisher
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product information
Catalog Number :
MAB3418
Subcategory :
Neuroscience
Product Name :
Anti-MAP2 Antibody, clone AP20
Product Type :
Antibodies
Clonality :
Monoclonal Antibody
Gene ID :
P11137
Host Name :
Mouse
Antigen :
MAP2
Clone :
AP20
Conjugate :
Purified
Isotype :
IgG
Product Description :
Anti-MAP2 Antibody, clone AP20
Cross Reactivity :
Bovine;Chicken;Human;Mouse;Rat;Xenopus;Quail
Background :
MAP-2 (microtubule associated protein-2) is one of several high molecular weight proteins that play an important role in brain neuron microtubule assembly. In addition to its association with microtubules, MAP-2 associates with neurofilaments and actin filaments suggesting that it may guide interaction among microtubules, other cytoskeletal elements, and cytoplasmic organelles. MAP-2 is a stringent marker for neurons. In addition, MAP-2 displays intracellular specificity. In the central nervous system, MAP-2 is confined to neuronal cell bodies and dendrites. There are exceptions, however, where some axons stain positive for small amounts of MAP-2. MAP-2 is uniformly distributed throughout the cell when first expressed in cultured neurons but becomes selectively localized as dendritic development proceeds. (Caceres, 1986; Dotti, 1987).
ALT Names :
Microtubule Associated Protein;MAP2A and 2B
Immunogen :
Bovine brain microtubule protein.
Specificity :
MAB3418 binds specifically to MAP-2.
Package Size :
200 µg
Uses :
Immunohistochemistry;Western Blotting
Storage :
Stable for 6 months at 2-8°C in undiluted aliquots from date of receipt. During shipment, small volumes of product will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap.
company information
EMD Millipore
290 Concord Road
Billerica, Massachusetts 01821
bioscienceshelp@emdchemical.com
https://www.emdmillipore.com
888-854-3417
headquarters: United States
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

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