This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
EMD Millipore
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
product type :
antibody
product name :
GABA A Receptor α1 chain Antibody, NT, clone BD24
catalog :
MAB339
quantity :
100 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
BD24
reactivity :
human, bovine, domestic rabbit
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry
citations: 22
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 4c
Fu Y, Zhang B, Mu T. LMAN1 (ERGIC-53) promotes trafficking of neuroreceptors. Biochem Biophys Res Commun. 2019;511:356-362 pubmed publisher
  • western blot; human; loading ...; fig 3a
Hernandez C, Kong W, Hu N, Zhang Y, Shen W, Jackson L, et al. Altered Channel Conductance States and Gating of GABAA Receptors by a Pore Mutation Linked to Dravet Syndrome. Eneuro. 2017;4: pubmed publisher
  • western blot; human; fig 1
Di X, Wang Y, Han D, Fu Y, Duerfeldt A, Blagg B, et al. Grp94 Protein Delivers γ-Aminobutyric Acid Type A (GABAA) Receptors to Hrd1 Protein-mediated Endoplasmic Reticulum-associated Degradation. J Biol Chem. 2016;291:9526-39 pubmed publisher
  • flow cytometry; human
Todd E, Gurba K, Botzolakis E, Stanic A, Macdonald R. GABAA receptor biogenesis is impaired by the ?2 subunit febrile seizure-associated mutation, GABRG2(R177G). Neurobiol Dis. 2014;69:215-24 pubmed publisher
  • immunocytochemistry; domestic rabbit; 4 ug/ml
Jakobs T, Koizumi A, Masland R. The spatial distribution of glutamatergic inputs to dendrites of retinal ganglion cells. J Comp Neurol. 2008;510:221-36 pubmed publisher
Han D, Di X, Fu Y, Mu T. Combining valosin-containing protein (VCP) inhibition and suberanilohydroxamic acid (SAHA) treatment additively enhances the folding, trafficking, and function of epilepsy-associated γ-aminobutyric acid, type A (GABAA) receptors. J Biol Chem. 2015;290:325-37 pubmed publisher
Reid S, Patassini S, Handley R, Rudiger S, McLaughlan C, Osmand A, et al. Further molecular characterisation of the OVT73 transgenic sheep model of Huntington's disease identifies cortical aggregates. J Huntingtons Dis. 2013;2:279-95 pubmed publisher
Puller C, Haverkamp S, Neitz M, Neitz J. Synaptic elements for GABAergic feed-forward signaling between HII horizontal cells and blue cone bipolar cells are enriched beneath primate S-cones. PLoS ONE. 2014;9:e88963 pubmed publisher
Lo W, Lagrange A, Hernandez C, Gurba K, Macdonald R. Co-expression of ?2 subunits hinders processing of N-linked glycans attached to the N104 glycosylation sites of GABAA receptor ?2 subunits. Neurochem Res. 2014;39:1088-103 pubmed publisher
Auferkorte O, Baden T, Kaushalya S, Zabouri N, Rudolph U, Haverkamp S, et al. GABA(A) receptors containing the ?2 subunit are critical for direction-selective inhibition in the retina. PLoS ONE. 2012;7:e35109 pubmed publisher
Rodrigues M, Martins A, Dias I, Viegas C, Neves N, Gomes M, et al. Synergistic effect of scaffold composition and dynamic culturing environment in multilayered systems for bone tissue engineering. J Tissue Eng Regen Med. 2012;6:e24-30 pubmed publisher
Gurba K, Hernandez C, Hu N, Macdonald R. GABRB3 mutation, G32R, associated with childhood absence epilepsy alters ?1?3?2L ?-aminobutyric acid type A (GABAA) receptor expression and channel gating. J Biol Chem. 2012;287:12083-97 pubmed publisher
Neumann S, Haverkamp S, Auferkorte O. Intrinsically photosensitive ganglion cells of the primate retina express distinct combinations of inhibitory neurotransmitter receptors. Neuroscience. 2011;199:24-31 pubmed publisher
Lachance Touchette P, Brown P, Meloche C, Kinirons P, Lapointe L, Lacasse H, et al. Novel ?1 and ?2 GABAA receptor subunit mutations in families with idiopathic generalized epilepsy. Eur J Neurosci. 2011;34:237-49 pubmed publisher
Waldvogel H, Baer K, Faull R. The localization of inhibitory neurotransmitter receptors on dopaminergic neurons of the human substantia nigra. J Neural Transm Suppl. 2009;:59-70 pubmed
Sacco C, Tardif E, Genoud C, Probst A, Tolnay M, Janzer R, et al. GABA receptor subunits in human auditory cortex in normal and stroke cases. Acta Neurobiol Exp (Wars). 2009;69:469-93 pubmed
Waldvogel H, Baer K, Eady E, Allen K, Gilbert R, Mohler H, et al. Differential localization of gamma-aminobutyric acid type A and glycine receptor subunits and gephyrin in the human pons, medulla oblongata and uppermost cervical segment of the spinal cord: an immunohistochemical study. J Comp Neurol. 2010;518:305-28 pubmed publisher
Lo W, Botzolakis E, Tang X, Macdonald R. A conserved Cys-loop receptor aspartate residue in the M3-M4 cytoplasmic loop is required for GABAA receptor assembly. J Biol Chem. 2008;283:29740-52 pubmed publisher
Waldvogel H, Baer K, Gai W, Gilbert R, Rees M, Mohler H, et al. Differential localization of GABAA receptor subunits within the substantia nigra of the human brain: an immunohistochemical study. J Comp Neurol. 2008;506:912-29 pubmed
Waldvogel H, Baer K, Allen K, Rees M, Faull R. Glycine receptors in the striatum, globus pallidus, and substantia nigra of the human brain: an immunohistochemical study. J Comp Neurol. 2007;502:1012-29 pubmed
Karakiulakis G, Papakonstantinou E, Aletras A, Tamm M, Roth M. Cell type-specific effect of hypoxia and platelet-derived growth factor-BB on extracellular matrix turnover and its consequences for lung remodeling. J Biol Chem. 2007;282:908-15 pubmed
Gastinger M, Barber A, Vardi N, Marshak D. Histamine receptors in mammalian retinas. J Comp Neurol. 2006;495:658-67 pubmed
product information
Catalog Number :
MAB339
Subcategory :
Neuroscience
Product Name :
Anti-GABA A Receptor α1 chain Antibody, NT, clone BD24
Product Type :
Antibodies
Clonality :
Monoclonal Antibody
Gene ID :
P14867
Host Name :
Mouse
Antigen :
GABA A Receptor α1 chain
Clone :
BD24
Conjugate :
Purified
Isotype :
IgG1
Product Description :
Anti-GABA A Receptor α1 chain Antibody, NT, clone BD24
Cross Reactivity :
Avian;Bovine;Human;Pig
Immunogen :
Purified GABA/benzodiazepine receptor from bovine cortex.
Specificity :
Reacts with the alpha 1-chain of the GABAA receptor in bovine and human but not rat
Package Size :
100 µg
Uses :
Immunohistochemistry;Immunoprecipitation;Western Blotting
Storage :
Maintain lyophilized material at +2-8°C for up to 12 months. After reconstitution maintain frozen at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.
company information
EMD Millipore
290 Concord Road
Billerica, Massachusetts 01821
bioscienceshelp@emdchemical.com
https://www.emdmillipore.com
888-854-3417
headquarters: United States
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

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