MMP-3 Antibody, clone SL-1 IID4 | EMD Millipore MAB3369 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

MMP-3 Antibody, clone SL-1 IID4

catalog :

MAB3369

quantity :

100 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

SL-1 IID4

The same clone is also sold as:

Invitrogen: MA5-14210
LifeSpan Biosciences: LS-C88492, LS-C88493, LS-C88494, LS-C85298

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunoprecipitation, immunohistochemistry - paraffin section

citations: 5

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; human; 1:100	Uchiyama A, Motegi S, Okada E, Hirai N, Nagai Y, Tamura A, et al. Cutaneous marginal zone B-cell lymphoma evolving into anetoderma: a role of matrix metalloproteinases?. Acta Derm Venereol. 2015;95:499-500 pubmed publisher
western blot; human	Romero A, Caceres M, Arancibia R, Silva D, Couve E, Martinez C, et al. Cigarette smoke condensate inhibits collagen gel contraction and prostaglandin E2 production in human gingival fibroblasts. J Periodontal Res. 2015;50:371-9 pubmed publisher
	Motegi S, Uchiyama A, Yamada K, Ogino S, Takeuchi Y, Ishikawa O. Blepharochalasis: possibly associated with matrix metalloproteinases. J Dermatol. 2014;41:536-8 pubmed publisher
	Shahed A, Young K. Differential activity of matrix metalloproteinases (MMPs) during photoperiod induced uterine regression and recrudescence in Siberian hamsters (Phodopus sungorus). Mol Reprod Dev. 2008;75:1433-40 pubmed publisher
	Baig S, Kehoe P, Love S. MMP-2, -3 and -9 levels and activity are not related to Abeta load in the frontal cortex in Alzheimer's disease. Neuropathol Appl Neurobiol. 2008;34:205-15 pubmed

product information

Catalog Number :

MAB3369

Subcategory :

Cell Structure

Product Name :

Anti-MMP-3 Antibody, clone SL-1 IID4

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P08254

Host Name :

Mouse

Antigen :

MMP-3

Clone :

SL-1 IID4

Conjugate :

Purified

Isotype :

IgG2b

Product Description :

Anti-MMP-3 Antibody, clone SL-1 IID4

Cross Reactivity :

Human

Background :

MMPs are frequently expressed in malignant neoplastic cells and play crucial roles in tumor invasion and metastasis. Tissue inhibitors of matrix metalloproteinases (TIMPs) control the activitiy of MMPS. The tissue distribution of three major MMPs has been defined in human mammary pathology: 1) collagenase (MMP-1) which degrades fibrillar interstitial collagens; 2) a 72-k/Da gelatinase (MMP-2) which mainly degrades type IV collagen and denatured collagens; and 3) stromelysin (MMP-3) which has a wider range of action, degrading several matrix components including the core proteins of proteoglycans, laminin and non-helical regions of collagens.

ALT Names :

Stromelysin-1; Transin; Proteoglycanase

Immunogen :

APMA (4-Aminophenylmercuric acetate) activated Human stromelysin-1

Specificity :

MAB3369 recognizes one doublet of 54kDa/59kDa and another doublet of 44kDa/49kDa, which are identified as unglycosylated and glycosylated species of pro (latent) and active forms of matrix metalloproteinase-3 (MMP-3; also known as Stromelysin-1 of Transin). MAB3369 shows no cross-reaction with the pro and active forms of other MMPs. CELLULAR LOCALIZATION: Cytoplasmic

Package Size :

100 µg

Uses :

ELISA;Immunoprecipitation;Western Blotting;Immunohistochemistry (Paraffin)

Storage :

Antibody with sodium azide is stable for 12 months when stored at 2-8°C.