This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
EMD Millipore
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
product type :
antibody
product name :
MMP-14 Antibody, hemopexin domain, clone 113-5B7
catalog :
MAB3317
quantity :
100 μg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
113-5B7
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
citations: 21
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - frozen section; rat
Guerra C, Carla Lara Pereira Y, Issa J, Luiz K, Guimarães E, Gerlach R, et al. Histological, histochemical, and protein changes after induced malocclusion by occlusion alteration of Wistar rats. Biomed Res Int. 2014;2014:563463 pubmed publisher
Johnson J, Jenkins N, Huang W, Di Gregoli K, Sala Newby G, Scholtes V, et al. Relationship of MMP-14 and TIMP-3 expression with macrophage activation and human atherosclerotic plaque vulnerability. Mediators Inflamm. 2014;2014:276457 pubmed publisher
Ranjan A, Kalraiya R. Invasive potential of melanoma cells correlates with the expression of MT1-MMP and regulated by modulating its association with motility receptors via N-glycosylation on the receptors. Biomed Res Int. 2014;2014:804680 pubmed publisher
Wang H, Zhang X, Huang L, Li J, Qu S, Pan F. Matrix metalloproteinase-14 expression and its prognostic value in cervical carcinoma. Cell Biochem Biophys. 2014;70:729-34 pubmed publisher
Ceron C, Rizzi E, Guimaraes D, Martins Oliveira A, Cau S, Ramos J, et al. Time course involvement of matrix metalloproteinases in the vascular alterations of renovascular hypertension. Matrix Biol. 2012;31:261-70 pubmed publisher
Aresu L, Giantin M, Morello E, Vascellari M, Castagnaro M, Lopparelli R, et al. Matrix metalloproteinases and their inhibitors in canine mammary tumors. BMC Vet Res. 2011;7:33 pubmed publisher
Lequerica Fernandez P, Pena I, Villalain L, Rosado P, De Vicente J. Carcinoma of the parotid gland: developing prognostic indices. Int J Oral Maxillofac Surg. 2011;40:821-8 pubmed publisher
Smith Pearson P, Greuber E, Yogalingam G, Pendergast A. Abl kinases are required for invadopodia formation and chemokine-induced invasion. J Biol Chem. 2010;285:40201-11 pubmed publisher
Klenotic P, Huang P, Palomo J, Kaur B, Van Meir E, Vogelbaum M, et al. Histidine-rich glycoprotein modulates the anti-angiogenic effects of vasculostatin. Am J Pathol. 2010;176:2039-50 pubmed publisher
Castro M, Rizzi E, Prado C, Rossi M, Tanus Santos J, Gerlach R. Imbalance between matrix metalloproteinases and tissue inhibitor of metalloproteinases in hypertensive vascular remodeling. Matrix Biol. 2010;29:194-201 pubmed publisher
Aplin A, Zhu W, Fogel E, Nicosia R. Vascular regression and survival are differentially regulated by MT1-MMP and TIMPs in the aortic ring model of angiogenesis. Am J Physiol Cell Physiol. 2009;297:C471-80 pubmed publisher
Kaur B, Cork S, Sandberg E, Devi N, Zhang Z, Klenotic P, et al. Vasculostatin inhibits intracranial glioma growth and negatively regulates in vivo angiogenesis through a CD36-dependent mechanism. Cancer Res. 2009;69:1212-20 pubmed publisher
Gooz P, Gooz M, Baldys A, Hoffman S. ADAM-17 regulates endothelial cell morphology, proliferation, and in vitro angiogenesis. Biochem Biophys Res Commun. 2009;380:33-8 pubmed publisher
Guigon C, Zhao L, Lu C, Willingham M, Cheng S. Regulation of beta-catenin by a novel nongenomic action of thyroid hormone beta receptor. Mol Cell Biol. 2008;28:4598-608 pubmed publisher
Liu C, Sun M, Yan X, Han L, Zhang Y, Liu C, et al. Inhibition of hepatic stellate cell activation following Yinchenhao decoction administration to dimethylnitrosamine-treated rats. Hepatol Res. 2008;38:919-29 pubmed publisher
Shahed A, Young K. Differential activity of matrix metalloproteinases (MMPs) during photoperiod induced uterine regression and recrudescence in Siberian hamsters (Phodopus sungorus). Mol Reprod Dev. 2008;75:1433-40 pubmed publisher
De Vicente J, Lequerica Fernandez P, Santamaria J, Fresno M. Expression of MMP-7 and MT1-MMP in oral squamous cell carcinoma as predictive indicator for tumor invasion and prognosis. J Oral Pathol Med. 2007;36:415-24 pubmed
Han Y, Yan C, Zhou L, Qin L, Tsukamoto H. A matrix metalloproteinase-9 activation cascade by hepatic stellate cells in trans-differentiation in the three-dimensional extracellular matrix. J Biol Chem. 2007;282:12928-39 pubmed
Roesch A, Wittschier S, Becker B, Landthaler M, Vogt T. Loss of dipeptidyl peptidase IV immunostaining discriminates malignant melanomas from deep penetrating nevi. Mod Pathol. 2006;19:1378-85 pubmed
Atkinson J, Holmbeck K, Yamada S, Birkedal Hansen H, Parks W, Senior R. Membrane-type 1 matrix metalloproteinase is required for normal alveolar development. Dev Dyn. 2005;232:1079-90 pubmed
Kajita M, Itoh Y, Chiba T, Mori H, Okada A, Kinoh H, et al. Membrane-type 1 matrix metalloproteinase cleaves CD44 and promotes cell migration. J Cell Biol. 2001;153:893-904 pubmed
product information
Catalog Number :
MAB3317
Subcategory :
Cell Structure
Product Name :
Anti-MMP-14 Antibody, hemopexin domain, clone 113-5B7
Product Type :
Antibodies
Clonality :
Monoclonal Antibody
Gene ID :
P50281
Host Name :
Mouse
Antigen :
MMP-14
Clone :
113-5B7
Conjugate :
Purified
Isotype :
IgG3κ
Product Description :
Anti-MMP-14 Antibody, hemopexin domain, clone 113-5B7
Cross Reactivity :
Bovine;Human;Mouse;Rat
ALT Names :
MT1-MMP
Immunogen :
CDGNFDTVAMLRGEM in the hemopexin-like domain of human MT1-MMP
Specificity :
Reacts with human MMP-14, also known as MT1-MMP, with a very slight cross-reactivity to hMMP-3. For unknown reasons this antibody does not react on westerns to CC1043.
Package Size :
100 μg
Uses :
ELISA;Immunohistochemistry (Paraffin);Western Blotting
Storage :
Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
company information
EMD Millipore
290 Concord Road
Billerica, Massachusetts 01821
bioscienceshelp@emdchemical.com
https://www.emdmillipore.com
888-854-3417
headquarters: United States
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

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