This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
EMD Millipore
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
product type :
antibody
product name :
Synaptophysin Antibody, clone SP15
catalog :
MAB329
quantity :
100 µL
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
SP15

The same clone is also sold as:
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
citations: 27
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; loading ...; fig 2a
Odawara A, Katoh H, Matsuda N, Suzuki I. Physiological maturation and drug responses of human induced pluripotent stem cell-derived cortical neuronal networks in long-term culture. Sci Rep. 2016;6:26181 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:4000
Deng X, Li M, Ai W, He L, Lu D, Patrylo P, et al. Lipolysaccharide-Induced Neuroinflammation Is Associated with Alzheimer-Like Amyloidogenic Axonal Pathology and Dendritic Degeneration in Rats. Adv Alzheimer Dis. 2014;3:78-93 pubmed
  • western blot; rat
Belzil C, Neumayer G, Vassilev A, Yap K, Konishi H, Rivest S, et al. A Ca2+-dependent mechanism of neuronal survival mediated by the microtubule-associated protein p600. J Biol Chem. 2013;288:24452-64 pubmed publisher
  • immunohistochemistry; mouse; 1:4000
Li J, Xue Z, Deng S, Luo X, Patrylo P, Rose G, et al. Amyloid plaque pathogenesis in 5XFAD mouse spinal cord: retrograde transneuronal modulation after peripheral nerve injury. Neurotox Res. 2013;24:1-14 pubmed publisher
  • immunohistochemistry; rat; 1:500
Griffin G, Ferri Kolwicz S, Reyes B, Van Bockstaele E, Flanagan Cato L. Ovarian hormone-induced reorganization of oxytocin-labeled dendrites and synapses lateral to the hypothalamic ventromedial nucleus in female rats. J Comp Neurol. 2010;518:4531-45 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:5000
Yan X, Xiong K, Luo X, Struble R, Clough R. beta-Secretase expression in normal and functionally deprived rat olfactory bulbs: inverse correlation with oxidative metabolic activity. J Comp Neurol. 2007;501:52-69 pubmed
  • immunohistochemistry - frozen section; mouse; 1:500
Navarro Quiroga I, Hernandez Valdes M, Lin S, Naegele J. Postnatal cellular contributions of the hippocampus subventricular zone to the dentate gyrus, corpus callosum, fimbria, and cerebral cortex. J Comp Neurol. 2006;497:833-45 pubmed
Roginski R, Lau C, Santoiemma P, Weaver S, Du P, Soteropoulos P, et al. The human GCOM1 complex gene interacts with the NMDA receptor and internexin-alpha. Gene. 2018;648:42-53 pubmed publisher
Sakaguchi K, Iima H, Matsuda K, Okamoto M, Hirayama K, Ikoma S, et al. Intestinal undifferentiated carcinoma in a red-crowned crane (Grus japonensis). J Vet Med Sci. 2013;75:827-30 pubmed
Lin D, Cao L, Wang Z, Li J, Washington J, Zuo Z. Lidocaine attenuates cognitive impairment after isoflurane anesthesia in old rats. Behav Brain Res. 2012;228:319-27 pubmed publisher
Cai Y, Zhang X, Macklin L, Cai H, Luo X, Oddo S, et al. BACE1 elevation is involved in amyloid plaque development in the triple transgenic model of Alzheimer's disease: differential Aβ antibody labeling of early-onset axon terminal pathology. Neurotox Res. 2012;21:160-74 pubmed publisher
Lin D, Feng C, Cao M, Zuo Z. Volatile anesthetics may not induce significant toxicity to human neuron-like cells. Anesth Analg. 2011;112:1194-8 pubmed publisher
Webster M, Elashoff M, Weickert C. Molecular evidence that cortical synaptic growth predominates during the first decade of life in humans. Int J Dev Neurosci. 2011;29:225-36 pubmed publisher
Cai Y, Xiong K, Zhang X, Cai H, Luo X, Feng J, et al. ?-Secretase-1 elevation in aged monkey and Alzheimer's disease human cerebral cortex occurs around the vasculature in partnership with multisystem axon terminal pathogenesis and ?-amyloid accumulation. Eur J Neurosci. 2010;32:1223-38 pubmed publisher
Zhang X, Xiong K, Cai Y, Cai H, Luo X, Feng J, et al. Functional deprivation promotes amyloid plaque pathogenesis in Tg2576 mouse olfactory bulb and piriform cortex. Eur J Neurosci. 2010;31:710-21 pubmed publisher
Zhang X, Cai Y, Xiong K, Cai H, Luo X, Feng J, et al. Beta-secretase-1 elevation in transgenic mouse models of Alzheimer's disease is associated with synaptic/axonal pathology and amyloidogenesis: implications for neuritic plaque development. Eur J Neurosci. 2009;30:2271-83 pubmed publisher
Roginski R, Goubaeva F, Mikami M, Fried Cassorla E, Nair M, Yang J. GRINL1A colocalizes with N-methyl D-aspartate receptor NR1 subunit and reduces N-methyl D-aspartate toxicity. Neuroreport. 2008;19:1721-6 pubmed publisher
Shim S, Wang J, Asada N, Neumayer G, Tran H, Ishiguro K, et al. Protein 600 is a microtubule/endoplasmic reticulum-associated protein in CNS neurons. J Neurosci. 2008;28:3604-14 pubmed publisher
Goddard M, Zheng Y, Darlington C, Smith P. Synaptic protein expression in the medial temporal lobe and frontal cortex following chronic bilateral vestibular loss. Hippocampus. 2008;18:440-4 pubmed publisher
Boyer F, Dreyer J. Alpha-synuclein in the nucleus accumbens induces changes in cocaine behaviour in rats. Eur J Neurosci. 2007;26:2764-76 pubmed
Yin W, Mendenhall J, Bratton S, Oung T, Janssen W, Morrison J, et al. Novel localization of NMDA receptors within neuroendocrine gonadotropin-releasing hormone terminals. Exp Biol Med (Maywood). 2007;232:662-73 pubmed
Gao J, Maison S, Wu X, Hirose K, Jones S, Bayazitov I, et al. Orphan glutamate receptor delta1 subunit required for high-frequency hearing. Mol Cell Biol. 2007;27:4500-12 pubmed
Xiong K, Cai H, Luo X, Struble R, Clough R, Yan X. Mitochondrial respiratory inhibition and oxidative stress elevate beta-secretase (BACE1) proteins and activity in vivo in the rat retina. Exp Brain Res. 2007;181:435-46 pubmed
Bragina L, Melone M, Fattorini G, Torres Ramos M, Vallejo Illarramendi A, Matute C, et al. GLT-1 down-regulation induced by clozapine in rat frontal cortex is associated with synaptophysin up-regulation. J Neurochem. 2006;99:134-41 pubmed
Kirouac G, Parsons M, Li S. Innervation of the paraventricular nucleus of the thalamus from cocaine- and amphetamine-regulated transcript (CART) containing neurons of the hypothalamus. J Comp Neurol. 2006;497:155-65 pubmed
Klucken J, Ingelsson M, Shin Y, Irizarry M, Hedley Whyte E, Frosch M, et al. Clinical and biochemical correlates of insoluble alpha-synuclein in dementia with Lewy bodies. Acta Neuropathol. 2006;111:101-8 pubmed
Kirouac G, Parsons M, Li S. Orexin (hypocretin) innervation of the paraventricular nucleus of the thalamus. Brain Res. 2005;1059:179-88 pubmed
product information
Catalog Number :
MAB329
Subcategory :
Neuroscience
Product Name :
Anti-Synaptophysin Antibody, clone SP15
Product Type :
Antibodies
Clonality :
Monoclonal Antibody
Gene ID :
P08247
Host Name :
Mouse
Antigen :
Synaptophysin
Clone :
SP15
Conjugate :
Ascites
Isotype :
IgM
Product Description :
Anti-Synaptophysin Antibody, clone SP15
Cross Reactivity :
Human;Hamster;Pig;Rat
ALT Names :
Major Synaptic Vesicle Protein p38
Immunogen :
Crude synaptic immunoprecipitate (Human)
Specificity :
Synaptophysin. Reacts with synaptophysin expressed in CHO cells.
Package Size :
100 µL
Uses :
ELISA;Western Blotting;Immunohistochemistry (Paraffin)
Storage :
Maintain frozen at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
company information
EMD Millipore
290 Concord Road
Billerica, Massachusetts 01821
bioscienceshelp@emdchemical.com
https://www.emdmillipore.com
888-854-3417
headquarters: United States
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

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