E-Cadherin Antibody, clone 67A4, Azide & Ascites Free | EMD Millipore MAB3199Z-C product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

E-Cadherin Antibody, clone 67A4, Azide & Ascites Free

catalog :

MAB3199Z-C

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

67A4

The same clone is also sold as:

MilliporeSigma: SAB4700237
Abnova: MAB9850, MAB9989
Novus Biologicals: NBP1-42793
BioLegend: 324118, 324115, 324127, 324103, 324108, 324113, 324116, 324102, 324121, 324110, 324125, 324104, 324106, 324107, 324123, 324112, 324120, 324124, 324105, 324114, 324122, 324101
Bio-Rad: MCA6135PE, MCA6135F, MCA6135APC, MCA6135
Exbio: 1F-588-T100, 1F-588-T025, 11-588-C025, 1P-588-T025, 1A-588-T100, 1A-588-T025, 11-588-C100, 1P-588-T100
LifeSpan Biosciences: LS-C112521, LS-C112614, LS-C204853, LS-C96302, LS-C112437
Santa Cruz Biotechnology: sc-21791, sc-21791 AC
Invitrogen: A15717, MA1-10192, A15757, MA1-10193, A15784, MA1-10194
Miltenyi Biotec: 130-095-413, 130-099-142, 130-099-688, 130-095-412, 130-099-723, 130-101-095, 130-101-148, 130-099-141
BD Biosciences: 563571
OriGene: AM26015PU-N, AM26015AC-N, AM26015FC-N, AM26015RP-N

reactivity :

human

application :

western blot, immunocytochemistry, flow cytometry

product information

Catalog Number :

MAB3199Z-C

Subcategory :

Cell Signaling

Product Name :

Anti-E-Cadherin Antibody, clone 67A4, Azide & Ascites Free

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P12830

Host Name :

Mouse

Antigen :

CDH1

Clone :

67A4

Conjugate :

Purified

Purification Method :

Protein G purified

Isotype :

IgG1κ

Product Description :

Anti-E-Cadherin Antibody, clone 67A4, Azide & Ascites Free

Cross Reactivity :

Human

Background :

Cadherins are a family of transmembrane glycoproteins involved in Ca2+-dependent cell to cell interactions. The members of the family are differentially expressed in various tissues and function in the maintenance of tissue integrity, morphogenesis, and migration. Cadherins are divided into type I and type II subgroups. Type I cadherins include epithelial cadherin (E-cadherin), neural cadherin (N-cadherin), placental cadherin (P-cadherin) and retinal cadherin (R-cadherin). Type II include kidney cadherin (K-cadherin) and osteoblast cadherin (OB-cadherin). One of the best characterized cadherins is E-cadherin (epithelial cadherin or cadherin-1). It consists of calcium binding extracellular domains responsible for interactions with other E-cadherin molecules on neighboring cells and interaction with integrin alphaEbeta7. The cytoplasmic domain of E-cadherin is linked to the actin cytoskeleton through cytoplasmic catenin proteins, thus establishing a complex localized to adherens junctions. In carcinomas E-cadherin is frequently downregulated, which is consistent with its function of an invasion suppressor in normal epithelia.

ALT Names :

Cadherin-1, CAM 120/80, Epithelial cadherin, E-cadherin, Uvomorulin, CD324

Immunogen :

Whole cells corresponding to human E-Cadherin.

Package Size :

100 μg

Uses :

Western Blotting, Flow Cytometry, Inhibition, Immunofluorescence

Storage :

Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.