This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
EMD Millipore
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
product type :
antibody
product name :
Dopamine β Hydroxylase Antibody, clone 4F10.2
catalog :
MAB308
quantity :
100 µL
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
4F10.2
reactivity :
long-tailed chinchilla, mouse, rat, bovine, pigs , domestic horse
application :
immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, immunohistochemistry - free floating section
citations: 98
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - frozen section; rat; 1:5000; loading ...; fig 4b
Costa Pereira J, Ribeiro J, Martins I, Tavares I. Role of Spinal Cord α2-Adrenoreceptors in Noradrenergic Inhibition of Nociceptive Transmission During Chemotherapy-Induced Peripheral Neuropathy. Front Neurosci. 2019;13:1413 pubmed publisher
  • immunohistochemistry; rat; 1:500; fig 1a1
Ghosh A, Torraville S, Mukherjee B, Walling S, Martin G, Harley C, et al. An experimental model of Braak's pretangle proposal for the origin of Alzheimer's disease: the role of locus coeruleus in early symptom development. Alzheimers Res Ther. 2019;11:59 pubmed publisher
  • immunohistochemistry - free floating section; mouse; fig 1
Schwartz M, Nguyen A, Warrier D, Palmerston J, Thomas A, Morairty S, et al. Locus Coeruleus and Tuberomammillary Nuclei Ablations Attenuate Hypocretin/Orexin Antagonist-Mediated REM Sleep. Eneuro. 2016;3: pubmed publisher
  • immunohistochemistry - frozen section; pigs
Jana B, Całka J, Rytel L, Czarzasta J. Morphological and neurochemical characterization of the ovarian sympathetic chain ganglia perikarya in testosterone-treated sexually matured pigs. Ann Anat. 2015;202:28-35 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:2500
Flak J, Myers B, Solomon M, McKlveen J, Krause E, Herman J. Role of paraventricular nucleus-projecting norepinephrine/epinephrine neurons in acute and chronic stress. Eur J Neurosci. 2014;39:1903-11 pubmed publisher
  • immunohistochemistry - free floating section; long-tailed chinchilla; 1:500
Nowak E. Organisation of autonomic nervous structures in the small intestine of chinchilla (Chinchilla laniger, Molina). Anat Histol Embryol. 2014;43:301-9 pubmed publisher
  • immunohistochemistry; rat
Lipski W, Grace A. Footshock-induced responses in ventral subiculum neurons are mediated by locus coeruleus noradrenergic afferents. Eur Neuropsychopharmacol. 2013;23:1320-8 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:3000
Bruinstroop E, Cano G, Vanderhorst V, Cavalcante J, Wirth J, Sena Esteves M, et al. Spinal projections of the A5, A6 (locus coeruleus), and A7 noradrenergic cell groups in rats. J Comp Neurol. 2012;520:1985-2001 pubmed publisher
  • immunohistochemistry - frozen section; domestic horse; 1:200
Russo D, Bombardi C, Grandis A, Furness J, Spadari A, Bernardini C, et al. Sympathetic innervation of the ileocecal junction in horses. J Comp Neurol. 2010;518:4046-66 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:10,000
Howorth P, Teschemacher A, Pickering A. Retrograde adenoviral vector targeting of nociresponsive pontospinal noradrenergic neurons in the rat in vivo. J Comp Neurol. 2009;512:141-57 pubmed publisher
Hunter D, Smaila B, Lopes D, Takatoh J, Denk F, Ramer M. Advillin Is Expressed in All Adult Neural Crest-Derived Neurons. Eneuro. 2018;5: pubmed publisher
Winter A, Ahlbrand R, Naik D, Sah R. Differential behavioral sensitivity to carbon dioxide (CO2) inhalation in rats. Neuroscience. 2017;346:423-433 pubmed publisher
Lee S, Diener K, KAUFMAN S, Krieger J, Pettersen K, Jejelava N, et al. Limiting glucocorticoid secretion increases the anorexigenic property of Exendin-4. Mol Metab. 2016;5:552-565 pubmed publisher
Nedelescu H, Chowdhury T, Wable G, ARBUTHNOTT G, Aoki C. Cerebellar sub-divisions differ in exercise-induced plasticity of noradrenergic axons and in their association with resilience to activity-based anorexia. Brain Struct Funct. 2017;222:317-339 pubmed publisher
Li Y, Hickey L, Perrins R, Werlen E, Patel A, Hirschberg S, et al. Retrograde optogenetic characterization of the pontospinal module of the locus coeruleus with a canine adenoviral vector. Brain Res. 2016;1641:274-90 pubmed publisher
Fyk Kolodziej B, Shimano T, Gafoor D, Mirza N, Griffith R, Gong T, et al. Dopamine in the auditory brainstem and midbrain: co-localization with amino acid neurotransmitters and gene expression following cochlear trauma. Front Neuroanat. 2015;9:88 pubmed publisher
Lepiarczyk E, Bossowska A, Majewski M. Changes in chemical coding of sympathetic chain ganglia (SChG) neurons supplying porcine urinary bladder after botulinum toxin (BTX) treatment. Cell Tissue Res. 2015;360:263-72 pubmed publisher
Menuet C, Sevigny C, Connelly A, Bassi J, Jancovski N, Williams D, et al. Catecholaminergic C3 neurons are sympathoexcitatory and involved in glucose homeostasis. J Neurosci. 2014;34:15110-22 pubmed publisher
Braegger F, Asarian L, Dahl K, Lutz T, Boyle C. The role of the area postrema in the anorectic effects of amylin and salmon calcitonin: behavioral and neuronal phenotyping. Eur J Neurosci. 2014;40:3055-66 pubmed publisher
Shin E, Rogers J, Devoto P, Bjorklund A, Carta M. Noradrenaline neuron degeneration contributes to motor impairments and development of L-DOPA-induced dyskinesia in a rat model of Parkinson's disease. Exp Neurol. 2014;257:25-38 pubmed publisher
Jokiaho A, Donovan C, Watts A. The rate of fall of blood glucose determines the necessity of forebrain-projecting catecholaminergic neurons for male rat sympathoadrenal responses. Diabetes. 2014;63:2854-65 pubmed publisher
Hickey L, Li Y, Fyson S, Watson T, Perrins R, Hewinson J, et al. Optoactivation of locus ceruleus neurons evokes bidirectional changes in thermal nociception in rats. J Neurosci. 2014;34:4148-60 pubmed publisher
Tang F, Lane S, Korsak A, Paton J, Gourine A, Kasparov S, et al. Lactate-mediated glia-neuronal signalling in the mammalian brain. Nat Commun. 2014;5:3284 pubmed publisher
Kreisler A, Davis E, Rinaman L. Differential activation of chemically identified neurons in the caudal nucleus of the solitary tract in non-entrained rats after intake of satiating vs. non-satiating meals. Physiol Behav. 2014;136:47-54 pubmed publisher
Yoshitake S, Kuteeva E, Hokfelt T, Mennicken F, Theodorsson E, Yamaguchi M, et al. Correlation between the effects of local and intracerebroventricular infusions of galanin on 5-HT release studied by microdialysis, and distribution of galanin and galanin receptors in prefrontal cortex, ventral hippocampus, amygdala, hypothalamus, a. Synapse. 2014;68:179-93 pubmed publisher
Messanvi F, Eggens Meijer E, Roozendaal B, van der Want J. A discrete dopaminergic projection from the incertohypothalamic A13 cell group to the dorsolateral periaqueductal gray in rat. Front Neuroanat. 2013;7:41 pubmed publisher
Bathina C, Rajulapati A, Franzke M, Yamamoto K, Cunningham J, Mifflin S. Knockdown of tyrosine hydroxylase in the nucleus of the solitary tract reduces elevated blood pressure during chronic intermittent hypoxia. Am J Physiol Regul Integr Comp Physiol. 2013;305:R1031-9 pubmed publisher
Jana B, Rytel L, Czarzasta J, Całka J. Reduction of the number of neurones in the caudal mesenteric ganglion innervating the ovary in sexually mature gilts following testosterone administration. J Neuroendocrinol. 2013;25:826-38 pubmed publisher
Hughes S, Hickey L, Hulse R, Lumb B, Pickering A. Endogenous analgesic action of the pontospinal noradrenergic system spatially restricts and temporally delays the progression of neuropathic pain following tibial nerve injury. Pain. 2013;154:1680-90 pubmed publisher
Lackovicova L, Gaykema R, Banovska L, Kiss A, Goehler L, Mravec B. The time-course of hindbrain neuronal activity varies according to location during either intraperitoneal or subcutaneous tumor growth in rats: single Fos and dual Fos/dopamine ?-hydroxylase immunohistochemistry. J Neuroimmunol. 2013;260:37-46 pubmed publisher
Stettner G, Lei Y, Benincasa Herr K, Kubin L. Evidence that adrenergic ventrolateral medullary cells are activated whereas precerebellar lateral reticular nucleus neurons are suppressed during REM sleep. PLoS ONE. 2013;8:e62410 pubmed publisher
Kozłowska A, Wojtkiewicz J, Majewski M, Jana B. The noradrenergic innervation and steroidogenic activity of porcine cystic ovaries. Physiol Res. 2013;62:421-33 pubmed
Laplante F, Mnie Filali O, Sullivan R. A neuroanatomical and neurochemical study of the indusium griseum and anterior hippocampal continuation: comparison with dentate gyrus. J Chem Neuroanat. 2013;50-51:39-47 pubmed publisher
Maniscalco J, Rinaman L. Overnight food deprivation markedly attenuates hindbrain noradrenergic, glucagon-like peptide-1, and hypothalamic neural responses to exogenous cholecystokinin in male rats. Physiol Behav. 2013;121:35-42 pubmed publisher
Herr K, Stettner G, Kubin L. Reduced c-Fos expression in medullary catecholaminergic neurons in rats 20 h after exposure to chronic intermittent hypoxia. Am J Physiol Regul Integr Comp Physiol. 2013;304:R514-22 pubmed publisher
Liu N, Schnell S, Wessendorf M, Gintzler A. Sex, pain, and opioids: interdependent influences of sex and pain modality on dynorphin-mediated antinociception in rats. J Pharmacol Exp Ther. 2013;344:522-30 pubmed publisher
Agster K, Mejías Aponte C, Clark B, Waterhouse B. Evidence for a regional specificity in the density and distribution of noradrenergic varicosities in rat cortex. J Comp Neurol. 2013;521:2195-207 pubmed publisher
Zhang J, Muller J, McDonald A. Noradrenergic innervation of pyramidal cells in the rat basolateral amygdala. Neuroscience. 2013;228:395-408 pubmed publisher
Gutierrez S, Hayashida K, Eisenach J. The puerperium alters spinal cord plasticity following peripheral nerve injury. Neuroscience. 2013;228:301-8 pubmed publisher
Kato K, Yokoyama T, Yamaguchi Yamada M, Yamamoto Y. Short-term hypoxia transiently increases dopamine ?-hydroxylase immunoreactivity in glomus cells of the rat carotid body. J Histochem Cytochem. 2013;61:55-62 pubmed publisher
Marcellino D, Frankowska M, Agnati L, Perez de la Mora M, Vargas Barroso V, Fuxe K, et al. Intercalated and paracapsular cell islands of the adult rat amygdala: a combined rapid-Golgi, ultrastructural, and immunohistochemical account. Neuroscience. 2012;226:324-47 pubmed publisher
Koszykowska M, Całka J, Nidzgorska A, Jana B. Exogenous long-term treatment with 17?-oestradiol alters the innervation pattern in pig ovary. Reprod Fertil Dev. 2013;25:661-73 pubmed publisher
Chambers A, Wilson Perez H, McGrath S, Grayson B, Ryan K, D Alessio D, et al. Effect of vertical sleeve gastrectomy on food selection and satiation in rats. Am J Physiol Endocrinol Metab. 2012;303:E1076-84 pubmed publisher
Nedungadi T, Dutta M, Bathina C, Caterina M, Cunningham J. Expression and distribution of TRPV2 in rat brain. Exp Neurol. 2012;237:223-37 pubmed publisher
Aizawa H, Kobayashi M, Tanaka S, Fukai T, Okamoto H. Molecular characterization of the subnuclei in rat habenula. J Comp Neurol. 2012;520:4051-66 pubmed publisher
True C, Grove K, Smith M. Beyond Leptin: Emerging Candidates for the Integration of Metabolic and Reproductive Function during Negative Energy Balance. Front Endocrinol (Lausanne). 2011;2:53 pubmed publisher
Kato K, Wakai J, Matsuda H, Kusakabe T, Yamamoto Y. Increased total volume and dopamine ?-hydroxylase immunoreactivity of carotid body in spontaneously hypertensive rats. Auton Neurosci. 2012;169:49-55 pubmed publisher
Hayashida K, Peters C, Gutierrez S, Eisenach J. Depletion of endogenous noradrenaline does not prevent spinal cord plasticity following peripheral nerve injury. J Pain. 2012;13:49-57 pubmed publisher
Potes C, Boyle C, Wookey P, Riediger T, Lutz T. Involvement of the extracellular signal-regulated kinase 1/2 signaling pathway in amylin's eating inhibitory effect. Am J Physiol Regul Integr Comp Physiol. 2012;302:R340-51 pubmed publisher
Mody P, Rukhadze I, Kubin L. Rats subjected to chronic-intermittent hypoxia have increased density of noradrenergic terminals in the trigeminal sensory and motor nuclei. Neurosci Lett. 2011;505:176-9 pubmed publisher
Lalatta Costerbosa G, Clavenzani P, Petrosino G, Mazzoni M. An immunohistochemical study of the distribution of nitric oxide synthase-immunoreactive neurons and fibers in the reticular groove of suckling lambs. J Anat. 2011;218:439-48 pubmed publisher
Skobowiat C, Calka J, Majewski M. Axotomy induced changes in neuronal plasticity of sympathetic chain ganglia (SChG) neurons supplying descending colon in the pig. Exp Mol Pathol. 2011;90:13-8 pubmed publisher
Gaykema R, Goehler L. Ascending caudal medullary catecholamine pathways drive sickness-induced deficits in exploratory behavior: brain substrates for fatigue?. Brain Behav Immun. 2011;25:443-60 pubmed publisher
Koszykowska M, Calka J, Szwajca P, Jana B. Long-term estradiol-17β administration decreases the number of neurons in the caudal mesenteric ganglion innervating the ovary in sexually mature gilts. J Reprod Dev. 2011;57:62-71 pubmed
Koszykowska M, Kozłowska A, Wojtkiewicz J, Skobowiat C, Majewski M, Jana B. Distribution and chemical coding of sympathetic neurons in the caudal mesenteric ganglion projecting to the ovary in sexually mature gilts. Acta Vet Hung. 2010;58:389-403 pubmed publisher
Northrop L, Polston E, Erskine M. Noradrenergic nuclei that receive sensory input during mating and project to the ventromedial hypothalamus play a role in mating-induced pseudopregnancy in the female rat. J Neuroendocrinol. 2010;22:1061-71 pubmed publisher
Lindstrom S, Azizi N, Weller C, Wilson M. Retinal input to efferent target amacrine cells in the avian retina. Vis Neurosci. 2010;27:103-18 pubmed publisher
Hayashida K, Eisenach J. A tropomyosine receptor kinase inhibitor blocks spinal neuroplasticity essential for the anti-hypersensitivity effects of gabapentin and clonidine in rats with peripheral nerve injury. J Pain. 2011;12:94-100 pubmed publisher
Potes C, Turek V, Cole R, Vu C, Roland B, Roth J, et al. Noradrenergic neurons of the area postrema mediate amylin's hypophagic action. Am J Physiol Regul Integr Comp Physiol. 2010;299:R623-31 pubmed publisher
Zhang Y, Kolli T, Hivley R, Jaber L, Zhao F, Yan J, et al. Characterization of the expression pattern of adrenergic receptors in rat taste buds. Neuroscience. 2010;169:1421-37 pubmed publisher
Skobowiat C, Gonkowski S, Calka J. Phenotyping of sympathetic chain ganglia (SChG) neurons in porcine colitis. J Vet Med Sci. 2010;72:1269-74 pubmed
Skobowiat C, Calka J, Wasowicz K, Majewski M. Distribution pattern and chemical coding of neurons of the sympathetic chain ganglia supplying the descending colon in the pig. Acta Vet Hung. 2010;58:189-98 pubmed publisher
Card J, Lois J, Sved A. Distribution and phenotype of Phox2a-containing neurons in the adult sprague-dawley rat. J Comp Neurol. 2010;518:2202-20 pubmed publisher
Suzuki G, Satow A, Ohta H. Effect of CFMTI, an allosteric metabotropic glutamate receptor 1 antagonist with antipsychotic activity, on Fos expression in regions of the brain related to schizophrenia. Neuroscience. 2010;168:787-96 pubmed publisher
Cragg J, Scott A, Ramer M. Depletion of spinal 5-HT accelerates mechanosensory recovery in the deafferented rat spinal cord. Exp Neurol. 2010;222:277-84 pubmed publisher
Carvalho A, Mackie K, Van Bockstaele E. Cannabinoid modulation of limbic forebrain noradrenergic circuitry. Eur J Neurosci. 2010;31:286-301 pubmed publisher
Sienkiewicz W, Dudek A, Kaleczyc J, Chrószcz A. Immunohistochemical characterization of neurones in the hypoglossal nucleus of the pig. Anat Histol Embryol. 2010;39:152-9 pubmed publisher
Hayashida K, Parker R, Eisenach J. Activation of glutamate transporters in the locus coeruleus paradoxically activates descending inhibition in rats. Brain Res. 2010;1317:80-6 pubmed publisher
Sonderegger S, Haslinger P, Sabri A, Leisser C, Otten J, Fiala C, et al. Wingless (Wnt)-3A induces trophoblast migration and matrix metalloproteinase-2 secretion through canonical Wnt signaling and protein kinase B/AKT activation. Endocrinology. 2010;151:211-20 pubmed publisher
Flak J, Ostrander M, Tasker J, Herman J. Chronic stress-induced neurotransmitter plasticity in the PVN. J Comp Neurol. 2009;517:156-65 pubmed publisher
Fuzesi T, Wittmann G, Lechan R, Liposits Z, Fekete C. Noradrenergic innervation of hypophysiotropic thyrotropin-releasing hormone-synthesizing neurons in rats. Brain Res. 2009;1294:38-44 pubmed publisher
Berglöf E, Small B, Bickford P, Stromberg I. Beneficial effects of antioxidant-enriched diet for tyrosine hydroxylase-positive neurons in ventral mesencephalic tissue in oculo grafts. J Comp Neurol. 2009;515:72-82 pubmed publisher
Lee S, Beak S, Park S, Waterhouse B, Lee H. Collateral projection from the locus coeruleus to whisker-related sensory and motor brain regions of the rat. J Comp Neurol. 2009;514:387-402 pubmed publisher
Brightwell J, Taylor B. Noradrenergic neurons in the locus coeruleus contribute to neuropathic pain. Neuroscience. 2009;160:174-85 pubmed publisher
Hayashida K, Obata H, Nakajima K, Eisenach J. Gabapentin acts within the locus coeruleus to alleviate neuropathic pain. Anesthesiology. 2008;109:1077-84 pubmed publisher
Pinard C, Muller J, Mascagni F, McDonald A. Dopaminergic innervation of interneurons in the rat basolateral amygdala. Neuroscience. 2008;157:850-63 pubmed publisher
Cano G, Mochizuki T, Saper C. Neural circuitry of stress-induced insomnia in rats. J Neurosci. 2008;28:10167-84 pubmed publisher
Rivera A, Penafiel A, Megias M, Agnati L, López Téllez J, Gago B, et al. Cellular localization and distribution of dopamine D(4) receptors in the rat cerebral cortex and their relationship with the cortical dopaminergic and noradrenergic nerve terminal networks. Neuroscience. 2008;155:997-1010 pubmed publisher
Ma S, Mifflin S, Cunningham J, Morilak D. Chronic intermittent hypoxia sensitizes acute hypothalamic-pituitary-adrenal stress reactivity and Fos induction in the rat locus coeruleus in response to subsequent immobilization stress. Neuroscience. 2008;154:1639-47 pubmed publisher
Radley J, Williams B, Sawchenko P. Noradrenergic innervation of the dorsal medial prefrontal cortex modulates hypothalamo-pituitary-adrenal responses to acute emotional stress. J Neurosci. 2008;28:5806-16 pubmed publisher
Chiocchetti R, Mazzuoli G, Albanese V, Mazzoni M, Clavenzani P, Lalatta Costerbosa G, et al. Anatomical evidence for ileal Peyer's patches innervation by enteric nervous system: a potential route for prion neuroinvasion?. Cell Tissue Res. 2008;332:185-94 pubmed publisher
Gaykema R, Park S, McKibbin C, Goehler L. Lipopolysaccharide suppresses activation of the tuberomammillary histaminergic system concomitant with behavior: a novel target of immune-sensory pathways. Neuroscience. 2008;152:273-87 pubmed
Gruber C, Kahl A, Lebenheim L, Kowski A, Dittgen A, Veh R. Dopaminergic projections from the VTA substantially contribute to the mesohabenular pathway in the rat. Neurosci Lett. 2007;427:165-70 pubmed
Schiltz J, Sawchenko P. Specificity and generality of the involvement of catecholaminergic afferents in hypothalamic responses to immune insults. J Comp Neurol. 2007;502:455-67 pubmed
Balcita Pedicino J, Rinaman L. Noradrenergic axon terminals contact gastric preautonomic neurons in the paraventricular nucleus of the hypothalamus in rats. J Comp Neurol. 2007;501:608-18 pubmed
Gabbott P, Warner T, Busby S. Catecholaminergic neurons in medullary nuclei are among the post-synaptic targets of descending projections from infralimbic area 25 of the rat medial prefrontal cortex. Neuroscience. 2007;144:623-35 pubmed
Drescher M, Drescher D, Khan K, Hatfield J, Ramakrishnan N, Abu Hamdan M, et al. Pituitary adenylyl cyclase-activating polypeptide (PACAP) and its receptor (PAC1-R) are positioned to modulate afferent signaling in the cochlea. Neuroscience. 2006;142:139-64 pubmed
Ranson R, Santer R, Watson A. The relationship between serotonin, dopamine beta hydroxylase and GABA immunoreactive inputs and spinal preganglionic neurones projecting to the major pelvic ganglion of Wistar rats. Neuroscience. 2006;141:1935-49 pubmed
Roozendaal B, Okuda S, Van der Zee E, McGaugh J. Glucocorticoid enhancement of memory requires arousal-induced noradrenergic activation in the basolateral amygdala. Proc Natl Acad Sci U S A. 2006;103:6741-6 pubmed
Stocker S, Wilson M, Madden C, Lone U, Sved A. Intravenous 6-hydroxydopamine attenuates vasopressin and oxytocin secretion stimulated by hemorrhage and hypotension but not hyperosmolality in rats. Am J Physiol Regul Integr Comp Physiol. 2006;291:R59-67 pubmed
Dey S, MacTutus C, Booze R, Snow D. Specificity of prenatal cocaine on inhibition of locus coeruleus neurite outgrowth. Neuroscience. 2006;139:899-907 pubmed
Matsunaga W, Isobe K, Shirokawa T. Involvement of neurotrophic factors in aging of noradrenergic innervations in hippocampus and frontal cortex. Neurosci Res. 2006;54:313-8 pubmed
Bréjot T, Blanchard S, Hocquemiller M, Haase G, Liu S, Nosjean A, et al. Forced expression of the motor neuron determinant HB9 in neural stem cells affects neurogenesis. Exp Neurol. 2006;198:167-82 pubmed
Nakai S, Matsunaga W, Isobe K, Shirokawa T. Age-dependent interactive changes in serotonergic and noradrenergic cortical axon terminals in F344 rats. Neurosci Res. 2006;54:220-9 pubmed
Nakai S, Matsunaga W, Ishida Y, Isobe K, Shirokawa T. Effects of BDNF infusion on the axon terminals of locus coeruleus neurons of aging rats. Neurosci Res. 2006;54:213-9 pubmed
Belcher S, Zsarnovszky A, Crawford P, Hemani H, Spurling L, Kirley T. Immunolocalization of ecto-nucleoside triphosphate diphosphohydrolase 3 in rat brain: implications for modulation of multiple homeostatic systems including feeding and sleep-wake behaviors. Neuroscience. 2006;137:1331-46 pubmed
Reynolds A, Kaasinen S, Hendry I. Retrograde axonal transport of dopamine beta hydroxylase antibodies by neurons in the trigeminal ganglion. Neurochem Res. 2005;30:703-12 pubmed
Fu Y, Cheng Y, Lin M, Cheng H, Chu P, Chou S, et al. Conversion of human umbilical cord mesenchymal stem cells in Wharton's jelly to dopaminergic neurons in vitro: potential therapeutic application for Parkinsonism. Stem Cells. 2006;24:115-24 pubmed
product information
Catalog Number :
MAB308
Subcategory :
Neuroscience
Product Name :
Anti-Dopamine β Hydroxylase Antibody, clone 4F10.2
Product Type :
Antibodies
Clonality :
Monoclonal Antibody
Gene ID :
P09172
Host Name :
Mouse
Antigen :
Dopamine β Hydroxylase
Clone :
4F10.2
Conjugate :
Ascites
Isotype :
IgG1
Product Description :
Anti-Dopamine β Hydroxylase Antibody, clone 4F10.2
Cross Reactivity :
Bovine;Rat;Sheep
Background :
Dopamine Beta Hydroxylase (DBH), the structural locus encoding DβH enzyme, is a major quantitative trait locus influencing plasma DβH activity, with one single nucleotide polymorphism (SNP) accounting for up to 50% of the variance. Mutations at DBH appear to be responsible for the rare syndrome of DβH deficiency. It functions as the only enzyme involved in the synthesis of small-molecule neurotransmitters that is membrane-bound, making norepinephrine and epinephrine the only transmitters synthesized inside vesicles. It is expressed in noradrenergic nerve terminals of the central and peripheral nervous systems, as well as in chromaffin cells of the adrenal medulla.
ALT Names :
DBH
Immunogen :
Purified bovine DBH.
Specificity :
Dopamine beta hydroxylase (DBH).
Package Size :
100 µL
Uses :
Immunohistochemistry;Immunohistochemistry (Paraffin);Immunofluorescence
Storage :
Stable for 1 year at -20ºC from date of receipt.
company information
EMD Millipore
290 Concord Road
Billerica, Massachusetts 01821
bioscienceshelp@emdchemical.com
https://www.emdmillipore.com
888-854-3417
headquarters: United States
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

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