VCAM-1 (CD106) Antibody, clone 6C7.1 | EMD Millipore MAB2627 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

VCAM-1 (CD106) Antibody, clone 6C7.1

catalog :

MAB2627

quantity :

100 μg

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

6C7.1

The same clone is also sold as:

OriGene: AM26309PU-N
LifeSpan Biosciences: LS-C139930

reactivity :

human, mouse

application :

immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry

citations: 5

Published Application/Species/Sample/Dilution	Reference
ELISA; human; 1:50; loading ...; fig 4a	Lee W, Ku S, Bae J. Anti-inflammatory effects of Baicalin, Baicalein, and Wogonin in vitro and in vivo. Inflammation. 2015;38:110-25 pubmed publisher
ELISA; human; 1:50; loading ...; fig 3	Jumpertz S, Hennes T, Asare Y, Vervoorts J, Bernhagen J, Schütz A. The ?-catenin E3 ubiquitin ligase SIAH-1 is regulated by CSN5/JAB1 in CRC cells. Cell Signal. 2014;26:2051-9 pubmed publisher
immunocytochemistry; human; 1:50; loading ...; fig 3a	Lee W, Ku S, Bae J. Vascular barrier protective effects of orientin and isoorientin in LPS-induced inflammation in vitro and in vivo. Vascul Pharmacol. 2014;62:3-14 pubmed publisher
	Lee W, Ku S, Min B, Lee S, Jee J, Kim J, et al. Vascular barrier protective effects of pellitorine in LPS-induced inflammation in vitro and in vivo. Fitoterapia. 2014;92:177-87 pubmed publisher
	Xing D, Bonanno J. Hypoxia reduces TGFbeta1-induced corneal keratocyte myofibroblast transformation. Mol Vis. 2009;15:1827-34 pubmed

product information

Catalog Number :

MAB2627

Subcategory :

Cell Structure

Product Name :

Anti-VCAM-1 (CD106) Antibody, clone 6C7.1

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P29533

Host Name :

Rat

Antigen :

VCAM-1 (CD106)

Clone :

6C7.1

Conjugate :

Purified

Isotype :

IgG1κ

Product Description :

Anti-VCAM-1 (CD106) Antibody, clone 6C7.1

Cross Reactivity :

Mouse

Background :

Vascular cell adhesion protein 1 (VCAM-1) is a cell surface adhesion molecule belonging to the immunoglobulin cell-cell adhesion receptor family and is comprised of seven Ig-like C2-type domains. VCAM-1 is a crucial component in cell-cell recognition and seems to be involved in cellular adhesion between endothelial cells and leukocytes. It has a regulatory role for both signal transduction and adhesion through its interaction with leukocyte beta-1 integrin VLA4, an interaction that is potentially involved in immune and inflammatory emigration responses of leukocytes. Studies have shown upregulation of VCAM-1 to be critical in responding to inflammatory diseases such as atherosclerosis. VCAM-1 is primarily expressed in endothelial cells and is expressed as two known isoforms found within the cell membrane. Isoform 1 functions as a single-pass type 1 membrane protein, while Isoform 2 acts as a GPI-anchor.

ALT Names :

vascular cell adhesion molecule 1;vascular cell adhesion protein 1;CD106 antigen

Immunogen :

Mouse endothelial cells

Package Size :

100 μg

Uses :

Flow Cytometry;Immunoprecipitation;Immunocytochemistry;Immunohistochemistry

Storage :

Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.