EMMPRIN [CD147] Antibody, clone 1S9-2A | EMD Millipore MAB2623 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

EMMPRIN [CD147] Antibody, clone 1S9-2A

catalog :

MAB2623

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1S9-2A

reactivity :

human, mouse

application :

western blot, immunohistochemistry, blocking or activating experiments

citations: 4

Published Application/Species/Sample/Dilution	Reference
blocking or activating experiments; mouse; fig s5i	Krampitz G, George B, Willingham S, Volkmer J, Weiskopf K, Jahchan N, et al. Identification of tumorigenic cells and therapeutic targets in pancreatic neuroendocrine tumors. Proc Natl Acad Sci U S A. 2016;113:4464-9 pubmed publisher
	Updegraff B, Zhou X, Guo Y, Padanad M, Chen P, Yang C, et al. Transmembrane Protease TMPRSS11B Promotes Lung Cancer Growth by Enhancing Lactate Export and Glycolytic Metabolism. Cell Rep. 2018;25:2223-2233.e6 pubmed publisher
	Heath C, Deep N, Beck L, Day K, Sweeny L, Zinn K, et al. Use of panitumumab-IRDye800 to image cutaneous head and neck cancer in mice. Otolaryngol Head Neck Surg. 2013;148:982-90 pubmed publisher
	Heath C, Deep N, Sweeny L, Zinn K, Rosenthal E. Use of panitumumab-IRDye800 to image microscopic head and neck cancer in an orthotopic surgical model. Ann Surg Oncol. 2012;19:3879-87 pubmed publisher

product information

Catalog Number :

MAB2623

Subcategory :

Cell Structure

Product Name :

Anti-EMMPRIN [CD147] Antibody, clone 1S9-2A

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P35613

Host Name :

Mouse

Antigen :

EMMPRIN [CD147]

Clone :

1S9-2A

Conjugate :

Purified

Isotype :

IgG2aκ

Product Description :

Anti-EMMPRIN [CD147] Antibody, clone 1S9-2A

Cross Reactivity :

Human

Background :

Matrix metalloproteinases (MMPs) or gelatinases play an important role in the early invasion of malignant tumors. These enzymes may be released directly from tumor cells, or may be derived from fibroblasts that have been stimulated with the extracellular MMP-inducer EMMPRIN. Studies have demonstrated that EMMPRIN stimulates human fibroblast production of interstitial collagenase, stromelysin-1, and gelatinase A (MMP-2), which is essential for tissue degradation and remodeling during tumor invasion and wound healing.

ALT Names :

Basigin;CD147 antigen;Collagenase stimulatory factor;Extracellular matrix metalloproteinase inducer;Leukocyte activation antigen M6;OK blood group antigen;Tumor cell-derived collagenase stimulatory factor;TCSF

Immunogen :

Human synovial fibroblasts.

Specificity :

The antibody recognizes EMMPRIN.

Package Size :

100 μg

Uses :

Western Blotting;Immunohistochemistry

Storage :

Stable for 1 year at 2-8°C from date of receipt