beta Arrestin 1 Antibody, clone 3H11.2 | EMD Millipore MAB2609 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

beta Arrestin 1 Antibody, clone 3H11.2

catalog :

MAB2609

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3H11.2

reactivity :

human

application :

western blot, immunocytochemistry

product information

Catalog Number :

MAB2609

Subcategory :

Cell Structure

Product Name :

Anti-beta Arrestin 1 Antibody, clone 3H11.2

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P49407

Host Name :

Mouse

Antigen :

beta Arrestin 1

Clone :

clone 3H11.2

Conjugate :

Purified

Isotype :

IgMκ

Product Description :

Anti-beta Arrestin 1 Antibody, clone 3H11.2

Cross Reactivity :

Human

Background :

The Arrestin family consists of four members: Arrestin 1 (visual Arrestin), Arrestin 2 (beta Arrestin 1), Arrestin 3 (beta Arrestin 2), and Arrestin 4 (cone Arrestin). While visual and cone Arrestins are found almost exclusively in the retina, beta Arrestins 1 and 2 are ubiquitously expressed. Beta Arrestins appear to act as negative regulators on G protein-coupled receptors, (Lefkowitz, 1998). Interaction with molecules such as clathrin, AP-2 and NSF directs the clathrin-mediated internalization of G-protein-coupled receptors. Interaction with molecules such as Src, Raf, Erk, ASK1 and JNK3 appears to regulate several pathways that result in the activation of MAP kinases, (Lin, 1998; Miller, 2001).

ALT Names :

Retinal S-antigen;Rod photoreceptor arrestin ;S-antigen; retina and pineal gland (arrestin) ;arrestin 1;retinal S-antigen (48 KDa protein)

Immunogen :

KLH conjugated synthetic peptide corresponding to amino acids 357-372 of human beta arrestin 1.

Specificity :

Reacts with human beta-arrestin 1.

Package Size :

100 μg

Uses :

Western Blotting;Immunofluorescence

Storage :

Maintain at 2-8°C in undiluted aliquots for up to 1 year after date of receipt.