ATG5 Antibody, clone 177.19 | EMD Millipore MAB2605 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

ATG5 Antibody, clone 177.19

catalog :

MAB2605

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

177.19

The same clone is also sold as:

BioLegend: 847410, 847401, 847405, 847408, 847402, 847407, 847406, 847409, 847403

reactivity :

human

application :

western blot, immunocytochemistry, immunoprecipitation, proximity ligation assay

citations: 3

Published Application/Species/Sample/Dilution	Reference
proximity ligation assay; human; loading ...; fig 5e, 7b immunoprecipitation; human; loading ...; fig 5a immunocytochemistry; human; loading ...; fig 5b, s8c western blot; human; loading ...; fig 5a, 6e	Lin T, Chan H, Chen S, Sarvagalla S, Chen P, Coumar M, et al. BIRC5/Survivin is a novel ATG12-ATG5 conjugate interactor and an autophagy-induced DNA damage suppressor in human cancer and mouse embryonic fibroblast cells. Autophagy. 2019;:1-18 pubmed publisher
	Jiang S, Xu W, Emery A, Gerfen C, Eiden M, Eiden L. NCS-Rapgef2, the Protein Product of the Neuronal Rapgef2 Gene, Is a Specific Activator of D1 Dopamine Receptor-Dependent ERK Phosphorylation in Mouse Brain. Eneuro. 2017;4: pubmed publisher
	Nakata Y, Brignier A, Jin S, Shen Y, Rudnick S, Sugita M, et al. c-Myb, Menin, GATA-3, and MLL form a dynamic transcription complex that plays a pivotal role in human T helper type 2 cell development. Blood. 2010;116:1280-90 pubmed publisher

product information

Catalog Number :

MAB2605

Subcategory :

Apoptosis & Cancer

Product Name :

Anti-ATG5 Antibody, clone 177.19

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

Q9H1Y0

Host Name :

Mouse

Antigen :

ATG5

Clone :

177.19

Conjugate :

Purified

Isotype :

IgG2bκ

Product Description :

Anti-ATG5 Antibody, clone 177.19

Cross Reactivity :

Human

Background :

ATG5 is required for autophagy. It conjugates to ATG12 and associates with isolation membrane to form autophagosomes. The conjugate detaches from the membrane immediately before or after autophagosome formation is completed. Conjugation to ATG12 is essential for autophagy, but is not required for association with isolation membrane. ATG5 also plays an important role in the apoptotic process. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity

ALT Names :

APG5 autophagy 5-like;APG5 autophagy 5-like (S. cerevisiae);APG5 (autophagy 5, S. cerevisiae)-like;ATG5 autophagy related 5 homolog (S. cerevisiae) ;ATG5 autophagy related 5-like;Apoptosis-specific protein;apoptosis specific protein

Immunogen :

Linear Peptide, aa: 8-318

Specificity :

The antibody reacts with the 50 kDa ATG5 protein.

Package Size :

100 μg

Uses :

Western Blotting;Immunoprecipitation

Storage :

Stable for 1 year at 2-8°C from date of receipt