Elastin Antibody, clone 10B8 | EMD Millipore MAB2503 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Elastin Antibody, clone 10B8

catalog :

MAB2503

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

10B8

reactivity :

human, mouse

application :

western blot, ELISA, immunocytochemistry, immunoprecipitation, immunohistochemistry - frozen section

citations: 16

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; 1:50; fig 1	Zoppi N, Chiarelli N, Cinquina V, Ritelli M, Colombi M. GLUT10 deficiency leads to oxidative stress and non-canonical Î±vÎ²3 integrin-mediated TGFÎ² signalling associated with extracellular matrix disarray in arterial tortuosity syndrome skin fibroblasts. Hum Mol Genet. 2015;24:6769-87 pubmed publisher
immunohistochemistry - frozen section; human	De Rosa L, Carulli S, Cocchiarella F, Quaglino D, Enzo E, Franchini E, et al. Long-term stability and safety of transgenic cultured epidermal stem cells in gene therapy of junctional epidermolysis bullosa. Stem Cell Reports. 2014;2:1-8 pubmed publisher
western blot; mouse	Ekman M, Bhattachariya A, Dahan D, Uvelius B, Albinsson S, Swärd K. Mir-29 repression in bladder outlet obstruction contributes to matrix remodeling and altered stiffness. PLoS ONE. 2013;8:e82308 pubmed publisher
	Nerurkar N, Mahadevan L, Tabin C. BMP signaling controls buckling forces to modulate looping morphogenesis of the gut. Proc Natl Acad Sci U S A. 2017;114:2277-2282 pubmed publisher
	Kasetti R, Phan T, Millar J, Zode G. Expression of Mutant Myocilin Induces Abnormal Intracellular Accumulation of Selected Extracellular Matrix Proteins in the Trabecular Meshwork. Invest Ophthalmol Vis Sci. 2016;57:6058-6069 pubmed publisher
	Kean T, Dennis J. Synoviocyte Derived-Extracellular Matrix Enhances Human Articular Chondrocyte Proliferation and Maintains Re-Differentiation Capacity at Both Low and Atmospheric Oxygen Tensions. PLoS ONE. 2015;10:e0129961 pubmed publisher
	Liu W, Atturo F, Aldaya R, Santi P, Cureoglu S, Obwegeser S, et al. Macromolecular organization and fine structure of the human basilar membrane - RELEVANCE for cochlear implantation. Cell Tissue Res. 2015;360:245-62 pubmed publisher
	Tan C, Tan E, Luo B, Huang C, Loo J, Choong C, et al. SMAD3 deficiency promotes inflammatory aortic aneurysms in angiotensin II-infused mice via activation of iNOS. J Am Heart Assoc. 2013;2:e000269 pubmed publisher
	Schlötzer Schrehardt U, Hammer C, Krysta A, Hofmann Rummelt C, Pasutto F, Sasaki T, et al. LOXL1 deficiency in the lamina cribrosa as candidate susceptibility factor for a pseudoexfoliation-specific risk of glaucoma. Ophthalmology. 2012;119:1832-43 pubmed publisher
	Lauer N, Mihlan M, Hartmann A, Schlötzer Schrehardt U, Keilhauer C, Scholl H, et al. Complement regulation at necrotic cell lesions is impaired by the age-related macular degeneration-associated factor-H His402 risk variant. J Immunol. 2011;187:4374-83 pubmed publisher
	Zode G, Sethi A, Brun Zinkernagel A, Chang I, Clark A, Wordinger R. Transforming growth factor-?2 increases extracellular matrix proteins in optic nerve head cells via activation of the Smad signaling pathway. Mol Vis. 2011;17:1745-58 pubmed
	Hu Q, Shifren A, Sens C, Choi J, Szabo Z, Starcher B, et al. Mechanisms of emphysema in autosomal dominant cutis laxa. Matrix Biol. 2010;29:621-8 pubmed publisher
	Schlötzer Schrehardt U, Pasutto F, Sommer P, Hornstra I, Kruse F, Naumann G, et al. Genotype-correlated expression of lysyl oxidase-like 1 in ocular tissues of patients with pseudoexfoliation syndrome/glaucoma and normal patients. Am J Pathol. 2008;173:1724-35 pubmed publisher
	Skeie J, Mullins R. Elastin-mediated choroidal endothelial cell migration: possible role in age-related macular degeneration. Invest Ophthalmol Vis Sci. 2008;49:5574-80 pubmed publisher
	Wachi H, Sato F, Nakazawa J, Nonaka R, Szabo Z, Urban Z, et al. Domains 16 and 17 of tropoelastin in elastic fibre formation. Biochem J. 2007;402:63-70 pubmed
	Sato F, Wachi H, Starcher B, Murata H, Amano S, Tajima S, et al. The characteristics of elastic fiber assembled with recombinant tropoelastin isoform. Clin Biochem. 2006;39:746-53 pubmed

product information

Catalog Number :

MAB2503

Subcategory :

Cell Structure

Product Name :

Anti-Elastin Antibody, clone 10B8

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P15502

Host Name :

Mouse

Antigen :

Elastin

Clone :

10B8

Conjugate :

Purified

Isotype :

Product Description :

Anti-Elastin Antibody, clone 10B8

Cross Reactivity :

Human;Mouse;Chicken;Bovine

Immunogen :

Tropoelastin from 17-day old lathyric chick embryo aortae, extracted an purified according to the method of Rich and Foster (1982) Meth. Enzymol. 82: 665-673.

Specificity :

Recognizes human Elastin. The antibody is also reactive with elastin from chicken, and bovine and mouse. Antibody specificity has been determined by immunoblotting of purified chick tropoelastin and immunoprecipitation of tritium-labeled chick tropoelastin from extracts of chick aorta organ cultures.

Package Size :

100 μg

Uses :

ELISA;Immunofluorescence;Immunoprecipitation;Western Blotting

Storage :

Maintain for 1 year at 2–8°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.